| PMC full text: | Published online 2023 Nov 15. doi: 10.5080/u27122
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Figure 1
The Mechanism of Action of Endocannabinoids
Endocannabinoids released from the postsynaptic neuron stimulate CB1 receptors in the presynaptic cell. Stimulation of CB1 receptors inhibits neurotransmitter release through both inhibition of presynaptic Ca+2 channels and reduction of cAMP levels.
ECB: endocannabinoids, CB1R: CB1 receptor, NT: neurotransmitter