Telomeric silencing defects of cac1 alleles. Tenfold serial dilutions of cells containing the URA3-VIIL telomere and the indicated cac1 alleles were plated onto SC −Trp or SC −Trp +FOA plates and grown for 5 days at 30°C. Strains used were (A) PKY619 (cac1Δ), (B) PKY618 (cac1Δ hir1Δ), and (C) PKY950 (cac1Δ asf1Δ).