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Statistics and ethics in medical research: III How large a sample?

British Medical Journal, 01 Nov 1980, 281(6251):1336-1338
https://doi.org/10.1136/bmj.281.6251.1336 PMID: 7437789 PMCID: PMC1714734

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Br Med J. 1980 Nov 15; 281(6251): 1336–1338.
PMCID: PMC1714734
PMID: 7437789

Statistics and ethics in medical research: III How large a sample?

D G Altman
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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Freiman JA, Chalmers TC, Smith H, Jr, Kuebler RR. The importance of beta, the type II error and sample size in the design and interpretation of the randomized control trial. Survey of 71 "negative" trials. N Engl J Med. 1978 Sep 28;299(13):690–694. [Abstract] [Google Scholar]
  • Newell DJ. Type II errors and ethics. Br Med J. 1978 Dec 23;2(6154):a1789–1789. [Europe PMC free article] [Google Scholar]
  • Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J, Smith PG. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. Br J Cancer. 1976 Dec;34(6):585–612. [Europe PMC free article] [Abstract] [Google Scholar]
  • Boag JW, Haybittle JL, Fowler JF, Emery EW. The number of patients required in a clinical trial. Br J Radiol. 1971 Feb;44(518):122–125. [Abstract] [Google Scholar]
  • Mould RF. Clinical trial design in cancer. Clin Radiol. 1979 Jul;30(4):371–381. [Abstract] [Google Scholar]
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