| PMC full text: | Arch Neurol. Author manuscript; available in PMC 2009 Jan 23. Published in final edited form as: Arch Neurol. 2008 Aug; 65(8): 1066–1073. doi: 10.1001/archneur.65.8.1066 |
Table 3
Case-Control Analyses for Diabetes Defined as Self-Report or as Abnormal Fasting Blood Glucose)
| Variable | Cases with MCI (n=329) n (%) | Controls (n=1640) n (%) | Model 1* | Model 2† | ||||
|---|---|---|---|---|---|---|---|---|
| Odds Ratio | 95% CI | P Value | Odds Ratio | 95% CI | P Value | |||
| Diabetes | ||||||||
 No diabetes | 249 (75.7) | 1309 (79.9) | 1.00 | -- | -- | 1.00 | -- | -- |
| Diabetes | 80 (24.3) | 330 (20.1) | 1.24‡ | 0.93-1.66 | .14 | 1.33 | 0.98-1.81 | .07 |
| Treatment type§ | ||||||||
| Diabetes, no treatment | 29 (8.8) | 148 (9.0) | 0.99 | 0.64-1.52 | .96 | 1.10 | 0.70-1.72 | .67 |
| Oral hypoglycemic | 26 (7.9) | 118 (7.2) | 1.13 | 0.72-1.80 | .59 | 1.18 | 0.73-1.91 | .49 |
| Insulin | 25 (7.6) | 64 (3.9) | 2.05 | 1.25-3.39 | .005 | 2.23 | 1.30-3.81 | .004 |
| Complications§ | ||||||||
| No complications | 53 (16.1) | 254 (15.5) | 1.06 | 0.76-1.49 | .72 | 1.16 | 0.81-1.65 | .41 |
| Any Complications | 27 (8.2) | 76 (4.6) | 1.84 | 1.15-2.95 | .01 | 1.93 | 1.16-3.21 | .01 |
| Neuropathy | 19 (5.8) | 49 (3.0) | 1.91 | 1.09-3.34 | .02 | 1.87 | 1.02-3.42 | .04 |
| Retinopathy | 13 (4.0) | 30 (1.8) | 2.15 | 1.09-4.22 | .03 | 2.36 | 1.17-4.79 | .02 |
| Nephropathy | 6 (1.8) | 21 (1.3) | 1.49 | 0.58-3.82 | .40 | 1.58 | 0.61-4.13 | .35 |
*Model 1: Adjusted for age, sex, and education.
†Model 2: Adjusted for age, sex, education, hypertension, stroke or transient ischemic attack, cigarette smoking, coronary artery disease, and body mass index.
‡The OR was 1.10 (95% CI, 0.78-1.53; P= .59) for a-MCI and 1.63 (95% CI, 1.01-2.63; P=.05) for na-MCI.
§The reference group included subjects without diabetes (same as first line in table).