Figure 3.

Immunological staining of DNAJC13 in brain sections from p.Asn855Ser mutation carriers SK1 II-7 (A–C) and SK1 II-9 (D–F). (A) Negative staining in hypoglossal motor neurons. (B) Finely granular cytoplasmic immunoreactivity in dorsal motor nucleus of vagus. A subset of Lewy bodies (<50%) were positively labeled (arrows). Some Lewy bodies were completely unstained (C) two in a locus coeruleus neuron; others had weak staining (D) dorsal motor nucleus and some had dark immunoreactivity (E and F) substantia nigra.