Logo of nihpaLink to Publisher's site
PMC full text:
Nano Lett. Author manuscript; available in PMC 2017 Jan 13.
Published in final edited form as:
Nano Lett. 2015 Apr 8; 15(4): 2249–2256.
Published online 2015 Mar 12. doi: 10.1021/nl504044p

Scheme 1

An external file that holds a picture, illustration, etc. Object name is nihms840084f6.jpg
Schematic Illustration of the Working Mechanism of X-PDTa

aA nanoscintillator core made of SAO is coated with two layers of silica, an inner solid layer and an outer mesoporous layer. Into the mesoporous silica layer, a photosensitizer, MC540, is loaded. Under X-ray irradiation, SAO converts X-rays to visible light photons (XEOL). The visible light photons, in turn, activate near-by MC540 molecules to produce cytotoxic 1O2 that destroys nearby cancer cells. 3O2 is the ground-state oxygen.

Images in this article

  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4
  • Figure 5
  • Scheme 1
Click on the image to see a larger version.