| PMC full text: | Published online 2017 Apr 21. doi: 10.1016/j.tranon.2017.03.008
|
Table 2
Univariate Cox Proportional Hazards Regression Analysis of Single Predictors for Recurrence-Free and Disease Specific Survival.
| Cytoband | Alteration | Disease Specific Survival | Recurrence-Free Survival | ||
|---|---|---|---|---|---|
| BH Corrected P-Value | CPH Coef. | BH Corrected P-Value | CPH Coef. | ||
| 1p36.33* | Amplification | 0.0327 | 1.0292 | 0.013 | 0.9185 |
| 1q23.2 | Amplification | 0.0269 | 0.8763 | 0.0934 | 0.574 |
| 3q27.2 | Amplification | 0.2467 | 0.436 | 0.2171 | 0.3823 |
| 11q13.3 | Amplification | 0.1232 | 0.4237 | 0.2142 | 0.2804 |
| 16p13.3 | Amplification | 0.0655 | 0.6641 | 0.0658 | 0.5375 |
| 16p11.2 | Amplification | 0.0497 | 0.8665 | 0.0549 | 0.6726 |
| 16q12.2 | Amplification | 0.0607 | 0.6662 | 0.0308 | 0.6497 |
| 2p11.2 | Deletion | 0.0473 | 1.0051 | 0.0844 | 0.777 |
| 2q22.1 | Deletion | 0.0147 | 1.0214 | 0.0623 | 0.6329 |
| 2q34 | Deletion | 0.0644 | 0.7772 | 0.0281 | 0.745 |
| 3p14.2 | Deletion | 0.1976 | 0.5665 | 0.2202 | 0.4236 |
| 4q13.2 | Deletion | 0.0582 | 0.8036 | 0.1775 | 0.4836 |
| 4q22.1 | Deletion | 0.0998 | 0.7098 | 0.2113 | 0.4591 |
| 9p23 | Deletion | 0.0969 | 0.711 | 0.1339 | 0.5327 |
| 11q22.3 | Deletion | 0.0829 | 0.7902 | 0.099 | 0.6467 |
| 6p21.1 | Amplification | 0.2198 | 0.4606 | - | - |
| 11q22.1 | Amplification | 0.1543 | 0.5204 | - | - |
| 18p11.31 | Amplification | 0.2227 | 0.5128 | - | - |
| 22q11.21 | Amplification | 0.1832 | −0.6038 | - | - |
| 1q31.3 | Deletion | 0.2371 | 0.5055 | - | - |
| 3p11.1 | Deletion | 0.0809 | 0.7957 | - | - |
| 4q13.2 | Deletion | 0.09 | 0.7457 | - | - |
| 5p14.3 | Deletion | 0.112 | 0.7583 | - | - |
| 7q31.1 | Deletion | 0.1624 | 0.598 | - | - |
| 13q21.32 | Deletion | 0.2166 | 0.5221 | - | - |
| 21q21.3 | Deletion | 0.1385 | 0.6243 | - | - |
| 2q37.3 | Amplification | - | - | 0.2185 | 0.3978 |
| 5p15.33 | Amplification | - | - | 0.223 | 0.3284 |
| 11p15.5 | Amplification | - | - | 0.1793 | 0.4287 |
| 13q21.33 | Amplification | - | - | 0.2436 | −0.7795 |
| 16q21 | Amplification | - | - | 0.1975 | 0.4048 |
| 19p13.3 | Amplification | - | - | 0.1465 | 0.3602 |
| 22q11.23 | Amplification | - | - | 0.1986 | −0.4272 |
| 9p21.3 | Deletion | - | - | 0.2007 | 0.4494 |
| 14q11.2 | Deletion | - | - | 0.1116 | 0.5358 |
| 17p13.1 | Deletion | - | - | 0.0346 | 0.7927 |
BH: Benjamini-Hochberg multiple testing correction method; CPH coef.: Cox Proportional Hazard coefficient. A positive regression coefficient means that the hazard is higher, thus the prognosis is worse; * Targets selected for validation; − represents not applicable.