| PMC full text: | Published online 2018 Jul 17. doi: 10.7554/eLife.35224
|
Table 1.
Representative listing of aggregate and aggregate associated proteins in oocyt nuclei.
Table 1—source data 1.
Retained proteins following depletion of soluble nuclear components.Click here to view.(94K, docx)
Table 1—source data 2.
Key with brief descriptions of the data sets.Click here to view.(66K, docx)
| Process | Gene name | Function (summarized from www.genecards.org) |
|---|---|---|
| DNA Replication | ||
| TOP2A | Topoisomerase II Alpha, DNA topoisomerase | |
| MCM2 | Minichromosome Maintenance Complex Component 2, involved in replication initiation | |
| POLE | DNA Polymerase Epsilon, Contributes to DNA repair and replication | |
| WRN | Werner Syndrome RecQ Like Helicase, DEAH 5' to 3' DNA with 3' to 5' exonuclease activity | |
| PRIM2 | Primase Subunit 2, DNA directed RNA polymerase that generates lagging | |
| RNA Processing | ||
| GTF2H2 | General Transcription Factor IIH Subunit 2, member of RNA pol II transcription initiation factor IIH complex | |
| SRRM1 | Serine and Arginine Repetitive Matrix 1, Part of pre- and post-splicing multiprotein mRNP complexes | |
| XAB2 | XPA Binding Protein 2, participates in mRNA splicing and nucleotide excision repair | |
| NOLC1 | Nucleolar and Coiled-Body Phosphoprotein, heavily modified regulator of RNA pol I | |
| SRSF5 | Serine Arginine Rich Splicing Factor 5, spliceosome component with an RRM and RS domains | |
| Transcription, DNA-templated | ||
| POLR1C | RNA Pol I subunit C, component of RNA Pol I and III complexes | |
| HSPA8 | Heat Shock Protein Family A Member 8, constitutively expressed member of HSP70 family | |
| NCL | Nucleolin, binds histone H1 to decondense DNA | |
| POLR1A | RNA pol I subunit A, catalytic and largest subunit or RNA Pol I complex | |
| POLR2E | RNA Pol II subunit E, subunit shared between RNA Pol I, II, and III | |
| Ribonucleoprotein Complex Biogenesis | ||
| PES1 | pescadillo, member of PeBoW complex and contributes to ribosome biogenesis, binds BRCA1 | |
| BOP1 | Block of Proliferation 1, participates in rRNA processing and is a member of PeBoW complex | |
| NPM1 | Nucleophosmin, multi-functional nucleolar phosphoprotein | |
| DDX21 | DEAD-Box Helicase 21, facilitates processing or RNA Pol I and II transcripts | |
| FBL | Fibrillarin, rRNA and protein methyltransferase | |