The long‐term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status

doi:10.1111/j.1440-1843.2010.01720.x

PMC full text:

Respirology. 2010 Apr; 15(3): 543–550.

Published online 2010 Mar 19. doi: 10.1111/j.1440-1843.2010.01720.x

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Table 2

Results of serial pulmonary function tests and respiratory muscle strength (% of predicted) among SARS survivors (n=55)

Tests conducted % predicted^†	3months	6months	12months	18months	24months	P‐value for trend
FVC	93.3 (13.7)	95.1 (13.7)	95.2 (12.9)	93.6 (12.6)	92.7 (13.1)	0.13
FEV₁	94.2 (12.5)	94.3 (12.2)	94.2 (12.1)	93.7 (12.3)	91.0 (14.2)	0.09
FEF_25–75	105.4 (30.6)	99.1 (30.6)	99.1 (32.3)	99.5 (30.1)	94.0 (35.4)	0.03^*
TLC	99.9 (20.0)	104.6 (18.4)	101.6 (18.4)	100.9 (14.9)	97.6 (15.4)	0.10
VC	97.2 (15.9)	97.7 (15.8)	97.6 (14.3)	95.5 (14.1)	95.0 (14.7)	0.05
RV	103.5 (50.6)	117.0 (39.1)	108.2 (47.1)	110.1 (29.1)	100.5 (34.2)	0.27
DL_CO	81.2 (18.8)	78.5 (19.1)	76.8 (15.4)	77.8 (13.5)	77.7 (13.3)	0.43
KCO	88.0 (15.6)	89.4 (12.3)	94.8 (10.5)	93.5 (11.6)	95.1 (10.4)	0.003^*
PImax	118.4 (30.1)	116.3 (27.4)	116.0 (29.6)	114.4 (21.3)	102.4 (33.3)	0.02^*
PEmax	76.3 (16.0)	80.0 (15.5)	81.0 (18.2)	74.2 (17.5)	75.1 (23.2)	0.11

Data presented as mean (SD).

^* P value

0.05.

^† FEV₁, FVC and FEF_25–75 reference values: Ip etal. 22

VC and TLC reference value: Da Costa. 20

DL_CO and KCO reference value: Ip etal. 23

FEF, forced expiratory flow; KCO, gas transfer corrected for alveolar volume; Pemax, maximum static expiratory pressure; Pimax, maximum static inspiratory pressure.