Aortic root dimensions as a correlate for aortic regurgitation’s severity

doi:10.1007/s10554-021-02337-6

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Int J Cardiovasc Imaging. 2021; 37(12): 3439–3449.

Published online 2021 Jul 7. doi: 10.1007/s10554-021-02337-6

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Table 2

Echocardiographic findings of the study population stratified by AR severity

	No AR (n=7007)	Mild AR (n=932)	Moderate/Severe AR (n=228)	p-value
Concomitant valvular disease
Mild AS	86 (1.3)	23 (2.8)	7 (3.4)	<0.001
Moderate/severe MR	189 (2.3)	74 (7.9)	19 (8.3)	<0.001
Moderate/severe TR	623 (8.9)	193 (20.7)	46 (20.2)	<0.001
Echocardiographic data
LVEF 2D, %	58.5±5.2	58.3+5.0	57.6±5.6	0.045
LVEF 3D, %	59.6±6.8	59.2±6.6	58.3±6.8	0.178
LVEDD, mm	47.7±5.2	47.9±5.3	48.9±6.4	0.004
LVEDV, ml	114.9±31.8	108.4±30.6	118.9±34.6	<0.001
TAPSE, mm	24.4±4.3	23.8±4.4	23.4±4.2	0.001
RV FAC, %	43.2±8.0	43.7±7.7	42.7±8.4	0.217
IVSD, mm	9.9±1.7	10.3±1.8	10.7±1.9	<0.001
E/e ‘	7.6±2.1	7.8±2.4	8.5±2.9	<0.001
LAVI, ml/m²	27.5±8.4	27.9±8.9	30.2±10.8	<0.001
LA Global Peak strain, %	39.8±14.4	38.5±15.4	37.0±14.5	0.014

Data are given as n (%) or mean±standard deviation, p-value for intergroup differences. All subjects with moderate/severe aortic stenosis or bicuspid valves were excluded from the analysis

AS aortic stenosis, IVST interventricular septum thickness, LA left atrial, LAVI left atrial volume index, LVEDD left ventricular end-diastolic diameter, LVEDV left ventricular end-diastolic volume, LVEF left ventricular ejection fraction, MR mitral regurgitation, MS mitral stenosis, RV FAC right ventricular fractional area change, TAPSE tricuspid annular peak systolic excursion, TR tricuspid regurgitation