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Mol Cell Biol. 2022 May; 42(5): e00546-21.
Published online 2022 Apr 12. https://doi.org/10.1128/mcb.00546-21
PMCID: PMC9119042
PMID: 35412342

Retraction for Ghoshal et al., “5-Aza-Deoxycytidine Induces Selective Degradation of DNA Methyltransferase 1 by a Proteasomal Pathway That Requires the KEN Box, Bromo-Adjacent Homology Domain, and Nuclear Localization Signal”

RETRACTION

The American Society for Microbiology (ASM) and Molecular and Cellular Biology hereby retract this article:

  Ghoshal K, Datta J, Majumder M, Bai S, Kutay H, Motiwala T, Jacob ST. 2005. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal. 25:4727–4741. https://doi.org/10.1128/MCB.25.11.4727-4741.2005.

The Ohio State University (OSU) informed Molecular and Cellular Biology and ASM that following an investigation of research misconduct, they found “falsified data” in Fig. 1A and B, 3D, and 6C-1 and C-2.

Based on these findings and an unsatifactory response from the authors, per ASM Publishing Ethics Policies and Procedures, we are abiding by the OSU retraction request. The integrity of the data presented was compromised; therefore, this publication is retracted in its entirety.

We apologize to the readers of Molecular and Cellular Biology and regret any inconvenience that this causes.


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