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Role of the risk signature in immunotherapeutic responses. (a) ESTIMATE algorithm was used to investigate the correlation between the two groups in immune scores and stromal scores. (b)–(e) The correlation between immunophenoscore and different risk groups. Low-risk subgroup was positively correlated with a lower IC50 of Docetaxel (f), Bleomycin (g), and Trametinb (j), while a higher IC50 of 5-Fluorouracil (h) and Mitomycin C (i). p < 0.01, p < 0.001, ns p > 0.05.