Glioblastoma: therapeutic challenges, what lies ahead.
Lima FR, Kahn SA, Soletti RC, Biasoli D, Alves T, da Fonseca AC, Garcia C, Romão L, Brito J, Holanda-Afonso R, Faria J, Borges H, Moura-Neto V
Biochim Biophys Acta, 1826(2):338-349, 05 Jun 2012
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Review
Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage.
Chao C, Wu Z, Mazur SJ, Borges H, Rossi M, Lin T, Wang JY, Anderson CW, Appella E, Xu Y
Mol Cell Biol, 26(18):6859-6869, 01 Sep 2006
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DNA damage-induced cell death: lessons from the central nervous system.
Cell Res, 18(1):17-26, 01 Jan 2008
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Review Free full text in Europe PMC
Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes.
Ledur PF, Karmirian K, Pedrosa CDSG, Souza LRQ, Assis-de-Lemos G, Martins TM, Ferreira JCCG, de Azevedo Reis GF, Silva ES, Silva D, Salerno JA, Ornelas IM, Devalle S, Madeiro da Costa RF, Goto-Silva L, Higa LM, Melo A, Tanuri A, Chimelli L, [...] Rehen SK
Sci Rep, 10(1):1218, 27 Jan 2020
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Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb.
Chau BN, Borges HL, Chen TT, Masselli A, Hunton IC, Wang JY
Nat Cell Biol, 4(10):757-765, 01 Oct 2002
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Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway.
Amado NG, Predes D, Fonseca BF, Cerqueira DM, Reis AH, Dudenhoeffer AC, Borges HL, Mendes FA, Abreu JG
J Biol Chem, 289(51):35456-35467, 30 Oct 2014
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Radiation-induced apoptosis in developing mouse retina exhibits dose-dependent requirement for ATM phosphorylation of p53.
Borges HL, Chao C, Xu Y, Linden R, Wang JY
Cell Death Differ, 11(5):494-502, 01 May 2004
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Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis, and favors glioblastoma resistance to etoposide.
Biasoli D, Kahn SA, Cornélio TA, Furtado M, Campanati L, Chneiweiss H, Moura-Neto V, Borges HL
Cell Death Dis, 4:e767, 15 Aug 2013
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Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Highlights in Resistance Mechanism Pathways for Combination Therapy.
Delou JMA, Souza ASO, Souza LCM, Borges HL
Cells, 8(9):E1013, 30 Aug 2019
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Review
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Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy.
Biasoli D, Sobrinho MF, da Fonseca AC, de Matos DG, Romão L, de Moraes Maciel R, Rehen SK, Moura-Neto V, Borges HL, Lima FR
Oncogenesis, 3:e123, 20 Oct 2014
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Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Potentiation of anticancer-drug cytotoxicity by sea anemone pore-forming proteins in human glioblastoma cells.
Soletti RC, de Faria GP, Vernal J, Terenzi H, Anderluh G, Borges HL, Moura-Neto V, Gabilan NH
Anticancer Drugs, 19(5):517-525, 01 Jun 2008
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Peptide gomesin triggers cell death through L-type channel calcium influx, MAPK/ERK, PKC and PI3K signaling and generation of reactive oxygen species.
Soletti RC, del Barrio L, Daffre S, Miranda A, Borges HL, Moura-Neto V, Lopez MG, Gabilan NH
Chem Biol Interact, 186(2):135-143, 28 Apr 2010
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The Chalcone Lonchocarpin Inhibits Wnt/β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation.
Predes D, Oliveira LFS, Ferreira LSS, Maia LA, Delou JMA, Faletti A, Oliveira I, Amado NG, Reis AH, Reis AH, Fraga CAM, Kuster R, Mendes FA, Borges HL, Abreu JG
Cancers (Basel), 11(12):E1968, 07 Dec 2019
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Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Tumor promotion by caspase-resistant retinoblastoma protein.
Borges HL, Bird J, Wasson K, Cardiff RD, Varki N, Eckmann L, Wang JY
Proc Natl Acad Sci U S A, 102(43):15587-15592, 14 Oct 2005
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Agathisflavone enhances retinoic acid-induced neurogenesis and its receptors α and β in pluripotent stem cells.
Paulsen BS, Souza CS, Chicaybam L, Bonamino MH, Bahia M, Costa SL, Borges HL, Rehen SK
Stem Cells Dev, 20(10):1711-1721, 18 Mar 2011
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Nuclear expression of β-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells.
Han J, Soletti RC, Sadarangani A, Sridevi P, Ramirez ME, Eckmann L, Borges HL, Wang JY
Mol Cancer Res, 11(3):207-218, 21 Jan 2013
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The Complex Link between Apoptosis and Autophagy: a Promising New Role for RB.
Delou JM, Biasoli D, Borges HL
An Acad Bras Cienc, 88(4):2257-2275, 01 Oct 2016
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Review
Therapeutic Potential of Naturally Occurring Small Molecules to Target the Wnt/β-Catenin Signaling Pathway in Colorectal Cancer.
Oliveira LFS, Predes D, Borges HL, Abreu JG
Cancers (Basel), 14(2):403, 14 Jan 2022
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Review
Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Inhibition of MAPK/ERK, PKC and CaMKII signaling blocks cytolysin-induced human glioma cell death.
Soletti RC, Alves T, Vernal J, Terenzi H, Anderluh G, Borges HL, Gabilan NH, Moura-Neto V
Anticancer Res, 30(4):1209-1215, 01 Apr 2010
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Non-permissive SARS-CoV-2 infection in human neurospheres.
Pedrosa CDSG, Goto-Silva L, Temerozo JR, Souza LRQ, Vitória G, Ornelas IM, Karmirian K, Mendes MA, Gomes IC, Sacramento CQ, Fintelman-Rodrigues N, Cardoso Soares V, Silva Gomes Dias SD, Salerno JA, Puig-Pijuan T, Oliveira JT, Aragão LGHS, Torquato TCQ, Veríssimo C, [...] Guimarães MZP
Stem Cell Res, 54:102436, 20 Jun 2021
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Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.p53 Signaling on Microenvironment and Its Contribution to Tissue Chemoresistance.
Souza LCME, Faletti A, Veríssimo CP, Stelling MP, Borges HL
Membranes (Basel), 12(2):202, 09 Feb 2022
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Review
Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Implications of aneuploidy for stem cell biology and brain therapeutics.
Devalle S, Sartore RC, Paulsen BS, Borges HL, Martins RA, Rehen SK
Front Cell Neurosci, 6:36, 05 Sep 2012
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Review
Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Reduction of apoptosis in Rb-deficient embryos via Abl knockout.
Oncogene, 26(26):3868-3877, 18 Dec 2006
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Death in a dish: controls of apoptosis within the developing retinal tissue.
Linden R, Rehen SK, Chiarini LB, Nakatani M, Rocha M, Campos CB, Borges HL, Varella MH, Freitas FG, Correa DF, Guimarães CA
Rev Bras Biol, 56 Su 1 Pt 1:89-103, 01 Dec 1996
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Review
WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2.
Aragão LGHS, Oliveira JT, Temerozo JR, Mendes MA, Salerno JA, Pedrosa CSG, Puig-Pijuan T, Veríssimo CP, Ornelas IM, Torquato T, Vitória G, Sacramento CQ, Fintelman-Rodrigues N, da Silva Gomes Dias S, Cardoso Soares V, Souza LRQ, Karmirian K, Goto-Silva L, Biagi D, [...] Rehen SK
PeerJ, 9:e12262, 08 Oct 2021
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Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Inhibition of pRB Pathway Differentially Modulates Apoptosis in Esophageal Cancer Cells.
Soletti RC, Biasoli D, Rodrigues NALV, Delou JMA, Maciel R, Chagas VLA, Martins RAP, Rehen SK, Borges HL
Transl Oncol, 10(5):726-733, 19 Jul 2017
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Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Immunohistochemical analysis of retinoblastoma and β-catenin as an assistant tool in the differential diagnosis between Crohn's disease and ulcerative colitis.
Soletti RC, Rodrigues NA, Biasoli D, Luiz RR, de Souza HS, Borges HL
PLoS One, 8(8):e70786, 14 Aug 2013
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Free full text in Europe PMCThis article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.Specific Cytostatic and Cytotoxic Effect of Dihydrochelerythrine in Glioblastoma Cells: Role of NF-κB/β-catenin and STAT3/IL-6 Pathways.
Silva TCC, de Faria Lopes GP, de J Menezes-Filho N, de Oliveira DM, Pereira E, Pitanga BPS, Dos Santos Costa R, da Silva Velozo E, Freire SM, Clarêncio J, Borges HL, Rehen SK, Moura-Neto V, Costa SL
Anticancer Agents Med Chem, 18(10):1386-1393, 01 Jan 2018
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Features of in vitro ultrasound biomicroscopic imaging and colonoscopy for detection of colon tumor in mice.
Alves KZ, Borges HL, Soletti RC, Viana AL, Petrella LI, Soldan M, Chagas VL, Schanaider A, Machado JC
Ultrasound Med Biol, 37(12):2086-2095, 26 Oct 2011
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In vivo endoluminal ultrasound biomicroscopic imaging in a mouse model of colorectal cancer.
Alves KZ, Soletti RC, de Britto MA, de Matos DG, Soldan M, Borges HL, Machado JC
Acad Radiol, 20(1):90-98, 05 Sep 2012
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Simultaneous follow-up of mouse colon lesions by colonoscopy and endoluminal ultrasound biomicroscopy.
Soletti RC, Alves KZ, de Britto MA, de Matos DG, Soldan M, Borges HL, Machado JC
World J Gastroenterol, 19(44):8056-8064, 01 Nov 2013
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3-D Endoluminal Ultrasound Biomicroscopic Imaging and Volumetry of Mouse Colon Tumors.
de Oliveira RP, Baptista RP, Martins CBC, Faletti A, Soletti RC, Borges HL, Machado JC
Ultrasound Med Biol, 47(10):2990-3001, 23 Jul 2021
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Could combinations of new and old drugs enhance tumor cell death?
Future Oncol, 14(23):2319-2322, 24 Aug 2018
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Trp53 Deletion Promotes Exacerbated Colitis, Facilitates Lgr5+ Cancer Stem Cell Expansion, and Fuels Tumorigenesis in AOM/DSS-Induced Colorectal Cancer.
Cunha AF, Delou JM, Barbosa PS, Conceição JSM, Souza KCS, Chagas V, Soletti RC, de Souza HSP, Borges HL
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Detection of Mice Colorectal Tumors by Endoluminal Ultrasound Biomicroscopic Images and Quantification of Image Augmented Gray Values Following Injection of VEGFR-2 Targeted Contrast Agent.
Soletti RC, de Britto MAP, Borges HL, Machado JC
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