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Search life-sciences literature (45,103,589 articles, preprints and more)

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TMEM106B amyloid filaments in the Biondi bodies of ependymal cells.
Ghetti B, Schweighauser M, Jacobsen MH, Gray D, Bacioglu M, Murzin AG, Glazier BS, Katsinelos T, Vidal R, Newell KL, Gao S, Garringer HJ, Spillantini MG, Scheres SHW, Goedert M
Acta Neuropathol, 148(1):60, 06 Nov 2024
Cited by: 0 articles | PMID: 39503754 | PMCID: PMC11541264
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Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP type C.
Arseni D, Nonaka T, Jacobsen MH, Murzin AG, Cracco L, Peak-Chew SY, Garringer HJ, Kawakami I, Suzuki H, Onaya M, Saito Y, Murayama S, Geula C, Vidal R, Newell KL, Mesulam M, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature, 634(8034):662-668, 11 Sep 2024
Cited by: 1 article | PMID: 39260416 | PMCID: PMC11485244
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Novel tau filament folds in individuals withMAPTmutations P301L and P301T
Schweighauser M, Shi Y, Murzin AG, Garringer HJ, Vidal R, Murrell JR, Erro ME, Seelaar H, Ferrer I, van Swieten JC, Ghetti B, Scheres SH, Goedert M
bioRxiv, 17 Aug 2024
Cited by: 0 articles | PPR: PPR897362
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Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C
Arseni D, Nonaka T, Jacobsen MH, Murzin AG, Cracco L, Peak-Chew SY, Garringer HJ, Kawakami I, Suzuki H, Onaya M, Saito Y, Murayama S, Geula C, Vidal R, Newell KL, Mesulam M, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
bioRxiv, 26 Jun 2024
Cited by: 0 articles | PPR: PPR873179
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Tau filaments with the Alzheimer fold in cases withMAPTmutations V337M and R406W
Qi C, Lövestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SH, Goedert M
bioRxiv, 30 Apr 2024
Cited by: 0 articles | PPR: PPR846426
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Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
Proc Natl Acad Sci U S A, 120(51):e2306767120, 15 Dec 2023
Cited by: 12 articles | PMID: 38100415 | PMCID: PMC10743375
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TAF15 amyloid filaments in frontotemporal lobar degeneration.
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature, 625(7994):345-351, 06 Dec 2023
Cited by: 8 articles | PMID: 38057661 | PMCID: PMC10781619
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Cryo-EM structures of Aβ40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.
Yang Y, Murzin AG, Peak-Chew S, Franco C, Garringer HJ, Newell KL, Ghetti B, Goedert M, Scheres SHW
Acta Neuropathol Commun, 11(1):191, 04 Dec 2023
Cited by: 6 articles | PMID: 38049918 | PMCID: PMC10694933
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Disease-specific tau filaments assemble via polymorphic intermediates.
Lövestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW
Nature, 625(7993):119-125, 29 Nov 2023
Cited by: 27 articles | PMID: 38030728 | PMCID: PMC10764278
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Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Schweighauser M, Murzin AG, Macdonald J, Lavenir I, Crowther RA, Scheres SHW, Goedert M
Acta Neuropathol Commun, 11(1):160, 05 Oct 2023
Cited by: 11 articles | PMID: 37798679 | PMCID: PMC10552433
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TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature, 620(7975):898-903, 02 Aug 2023
Cited by: 34 articles | PMID: 37532939 | PMCID: PMC10447236
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Cryo-EM structures of Aβ40 filaments from the leptomeninges of individuals with Alzheimer’s disease and cerebral amyloid angiopathy
Yang Y, Murzin AG, Peak-Chew S, Franco C, Newell KL, Ghetti B, Goedert M, Scheres SH
bioRxiv, 07 Oct 2023
Cited by: 0 articles | PPR: PPR738042
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Cryo-EM structures of Tau filaments from the brains of mice transgenic for human mutant P301S Tau
Schweighauser M, Murzin AG, Macdonald J, Lavenir IL, Crowther RA, Scheres SH, Goedert M
bioRxiv, 01 Sep 2023
Cited by: 0 articles | PPR: PPR717687
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Disease-specific tau filaments assemble via polymorphic intermediates
Lövestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SM, Goedert M, Scheres SH
bioRxiv, 26 Jul 2023
Cited by: 0 articles | PPR: PPR697663
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Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SH, Goedert M
bioRxiv, 28 Apr 2023
Cited by: 0 articles | PPR: PPR652091
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New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy.
Yang Y, Garringer HJ, Shi Y, Lövestam S, Peak-Chew S, Zhang X, Kotecha A, Bacioglu M, Koto A, Takao M, Spillantini MG, Ghetti B, Vidal R, Murzin AG, Scheres SHW, Goedert M
Acta Neuropathol, 145(5):561-572, 27 Feb 2023
Cited by: 20 articles | PMID: 36847833 | PMCID: PMC10119069
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Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains.
Yang Y, Zhang W, Murzin AG, Schweighauser M, Huang M, Lövestam S, Peak-Chew SY, Saito T, Saido TC, Macdonald J, Lavenir I, Ghetti B, Graff C, Kumar A, Nordberg A, Goedert M, Scheres SHW
Acta Neuropathol, 145(3):325-333, 07 Jan 2023
Cited by: 24 articles | PMID: 36611124 | PMCID: PMC9925504
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NewSNCAmutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy
Yang Y, Garringer HJ, Shi Y, Lövestam S, Zhang X, Kotecha A, Bacioglu M, Koto A, Takao M, Spillantini MG, Ghetti B, Vidal R, Murzin AG, Scheres SH, Goedert M
bioRxiv, 28 Nov 2022
Cited by: 0 articles | PPR: PPR576400
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Cryo-EM Structures of Amyloid-β Filaments With the Arctic Mutation (E22G) From Human and Mouse Brains
Yang Y, Zhang W, Murzin AG, Schweighauser M, Huang M, Lövestam S, Peak-Chew SY, Saito T, Saido TC, Macdonald J, Lavenir I, Ghetti B, Graff C, Kumar A, Nordberg A, Goedert M, Scheres SH
bioRxiv, 07 Nov 2022
Cited by: 0 articles | PPR: PPR568003
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Structures of α-synuclein filaments from human brains with Lewy pathology.
Yang Y, Shi Y, Schweighauser M, Zhang X, Kotecha A, Murzin AG, Garringer HJ, Cullinane PW, Saito Y, Foroud T, Warner TT, Hasegawa K, Vidal R, Murayama S, Revesz T, Ghetti B, Hasegawa M, Lashley T, Scheres SHW, Goedert M
Nature, 610(7933):791-795, 15 Sep 2022
Cited by: 131 articles | PMID: 36108674 | PMCID: PMC7613749
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Cryo-EM structures of α-synuclein filaments from Parkinson’s disease and dementia with Lewy bodies
Yang Y, Shi Y, Schweighauser M, Zhang X, Kotecha A, Murzin AG, Garringer HJ, Cullinane PW, Saito Y, Foroud T, Warner TT, Hasegawa K, Vidal R, Murayama S, Revesz T, Ghetti B, Hasegawa M, Lashley T, Scheres SH, Goedert M
bioRxiv, 12 Jul 2022
Cited by: 0 articles | PPR: PPR517231
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Age-dependent formation of TMEM106B amyloid filaments in human brains.
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lövestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, Miyazaki M, Saito Y, Yoshida M, Hasegawa K, [...] Scheres SHW
Nature, 605(7909):310-314, 28 Mar 2022
Cited by: 86 articles | PMID: 35344985 | PMCID: PMC9095482
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Structure of pathological TDP-43 filaments from ALS with FTLD.
Arseni D, Hasegawa M, Murzin AG, Kametani F, Arai M, Yoshida M, Ryskeldi-Falcon B
Nature, 601(7891):139-143, 08 Dec 2021
Cited by: 122 articles | PMID: 34880495 | PMCID: PMC7612255
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Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Lövestam S, Koh FA, van Knippenberg B, Kotecha A, Murzin AG, Goedert M, Scheres SHW
Elife, 11:e76494, 04 Mar 2022
Cited by: 107 articles | PMID: 35244536 | PMCID: PMC8983045
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Cryo-EM Structures of Amyloid-β 42 Filaments from Human Brain
Yang Y, Arseni D, Zhang W, Huang M, Lövestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew SY, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, Vidal R, Ghetti B, Falcon B, Scheres SH, Goedert M
bioRxiv, 19 Oct 2021
Cited by: 0 articles | PPR: PPR409041
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