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Suggested authors matching "AUTH:Adorini L" with an ORCID

Luciano Adorini
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Increased hepatoprotective effects of the novel farnesoid X receptor agonist INT-787 versus obeticholic acid in a mouse model of nonalcoholic steatohepatitis.
Adorini L, Rigbolt K, Feigh M, Roth J, Erickson M
PLoS One, 19(4):e0300809, 25 Apr 2024
Cited by: 0 articles | PMID: 38662778 | PMCID: PMC11045142
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FXR agonists INT-787 and OCA increase RECK and inhibit liver steatosis and inflammation in diet-induced ob/ob mouse model of NASH.
Di Pasqua LG, Cagna M, Palladini G, Croce AC, Cadamuro M, Fabris L, Perlini S, Adorini L, Ferrigno A, Vairetti M
Liver Int, 44(1):214-227, 30 Oct 2023
Cited by: 5 articles | PMID: 37904642
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Farnesoid X receptor enhances epithelial ACE2 expression and inhibits virally induced IL-6 secretion: implications for intestinal symptoms of SARS-CoV-2.
Smyth JS, Truong JK, Rao A, Lin R, Foulke-Abel J, Adorini L, Donowitz M, Dawson PA, Keely SJ
Am J Physiol Gastrointest Liver Physiol, 325(5):G446-G452, 12 Sep 2023
Cited by: 2 articles | PMID: 37697930 | PMCID: PMC10887846
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FXR agonists in NASH treatment.
Adorini L, Trauner M
J Hepatol, 79(5):1317-1331, 09 Aug 2023
Cited by: 12 articles | PMID: 37562746
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An integrated analysis of fecal microbiome and metabolomic features distinguish non-cirrhotic NASH from healthy control populations.
Carr RM, Li Y, Chau L, Chau L, Friedman ES, Lee JJ, Adorini L, Adorini L, Erickson M, Zaru L, Shringarpure R, MacConell L, Bittinger K, Li H, Wu GD
Hepatology, 78(6):1843-1857, 25 May 2023
Cited by: 1 article | PMID: 37222264
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The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice.
Wang XX, Xie C, Libby AE, Ranjit S, Levi J, Myakala K, Bhasin K, Jones BA, Orlicky DJ, Takahashi S, Dvornikov A, Kleiner DE, Hewitt SM, Adorini L, Kopp JB, Krausz KW, Rosenberg A, McManaman JL, Robertson CE, [...] Levi M
J Biol Chem, 298(11):102530, 07 Oct 2022
Cited by: 14 articles | PMID: 36209823 | PMCID: PMC9638804
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Altered ethanol metabolism and increased oxidative stress enhance alcohol-associated liver injury in farnesoid X receptor-deficient mice.
Morel C, Chowdhary V, Thevkar Nagesh P, Ribeiro M, Hawryluk D, Catalano D, Adorini L, Szabo G
Liver Int, 43(1):100-114, 08 Aug 2022
Cited by: 1 article | PMID: 35869657 | PMCID: PMC10501031
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Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow.
Marzano M, Fosso B, Colliva C, Notario E, Passeri D, Intranuovo M, Gioiello A, Adorini L, Pesole G, Pellicciari R, Moschetta A, Gadaleta RM
Biomed Pharmacother, 153:113380, 19 Jul 2022
Cited by: 7 articles | PMID: 36076475
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Enterohepatic Takeda G-Protein Coupled Receptor 5 Agonism in Metabolic Dysfunction-Associated Fatty Liver Disease and Related Glucose Dysmetabolism.
Gillard J, Picalausa C, Ullmer C, Adorini L, Staels B, Tailleux A, Leclercq IA
Nutrients, 14(13):2707, 29 Jun 2022
Cited by: 7 articles | PMID: 35807885 | PMCID: PMC9268629
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UDCA and INT-777 suppress cardiac fibrosis triggered by IL-11 through involvement of TGR5
Reilly-O’Donnell B, Ferraro E, Tikhomirov R, Nunez-Toldra R, Shchendrygina A, Patel L, Wu Y, Mitchell AL, Endo A, Adorini L, Chowdhury RA, Srivastava PK, Ng FS, Terracciano CM, Williamson C, Gorelik J
medRxiv, 16 May 2022
Cited by: 0 articles | PPR: PPR493474
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Obeticholic Acid Reduces Kidney Matrix Metalloproteinase Activation Following Partial Hepatic Ischemia/Reperfusion Injury in Rats.
Palladini G, Cagna M, Di Pasqua LG, Adorini L, Croce AC, Perlini S, Ferrigno A, Berardo C, Vairetti M
Pharmaceuticals (Basel), 15(5):524, 24 Apr 2022
Cited by: 1 article | PMID: 35631351 | PMCID: PMC9145209
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Inhibition of autotaxin by bile salts and bile salt-like molecules increases its expression by feedback regulation.
Langedijk JAGM, Tolenaars D, Bolier R, Lee YT, Meurs A, Williamson C, Adorini L, van de Graaf SFJ, Beuers U, Elferink RO
Biochim Biophys Acta Mol Basis Dis, 1867(11):166239, 10 Aug 2021
Cited by: 3 articles | PMID: 34389475
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Obeticholic acid reduces biliary and hepatic matrix metalloproteinases activity in rat hepatic ischemia/reperfusion injury.
Ferrigno A, Palladini G, Di Pasqua LG, Berardo C, Richelmi P, Cadamuro M, Fabris L, Perlini S, Adorini L, Vairetti M
PLoS One, 15(9):e0238543, 10 Sep 2020
Cited by: 8 articles | PMID: 32911524 | PMCID: PMC7482919
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Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia.
Pataia V, McIlvride S, Papacleovoulou G, Ovadia C, McDonald JAK, Wahlström A, Jansen E, Adorini L, Shapiro D, Marchesi JR, Marschall HU, Williamson C
Am J Physiol Gastrointest Liver Physiol, 319(2):G197-G211, 29 Jun 2020
Cited by: 3 articles | PMID: 32597707 | PMCID: PMC7500267
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Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH.
Baandrup Kristiansen MN, Veidal SS, Christoffersen C, Feigh M, Vrang N, Roth JD, Erickson M, Adorini L, Jelsing J
BMC Gastroenterol, 19(1):228, 28 Dec 2019
Cited by: 7 articles | PMID: 31883514 | PMCID: PMC6935483
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Obeticholic acid and INT-767 modulate collagen deposition in a NASH in vitro model.
Anfuso B, Tiribelli C, Adorini L, Rosso N
Sci Rep, 10(1):1699, 03 Feb 2020
Cited by: 18 articles | PMID: 32015483 | PMCID: PMC6997404
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Obeticholic acid ameliorates dyslipidemia but not glucose tolerance in mouse model of gestational diabetes.
McIlvride S, Nikolova V, Fan HM, McDonald JAK, Wahlström A, Bellafante E, Jansen E, Adorini L, Shapiro D, Jones P, Marchesi JR, Marschall HU, Williamson C
Am J Physiol Endocrinol Metab, 317(2):E399-E410, 25 Jun 2019
Cited by: 7 articles | PMID: 31237448 | PMCID: PMC6732461
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Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development.
Mouries J, Brescia P, Silvestri A, Spadoni I, Sorribas M, Wiest R, Mileti E, Galbiati M, Invernizzi P, Adorini L, Penna G, Rescigno M
J Hepatol, 71(6):1216-1228, 13 Aug 2019
Cited by: 258 articles | PMID: 31419514 | PMCID: PMC6880766
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Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH.
Roth JD, Veidal SS, Fensholdt LKD, Rigbolt KTG, Papazyan R, Nielsen JC, Feigh M, Vrang N, Young M, Jelsing J, Adorini L, Hansen HH
Sci Rep, 9(1):9046, 21 Jun 2019
Cited by: 22 articles | PMID: 31227742 | PMCID: PMC6588626
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Therapeutic effects of the selective farnesoid X receptor agonist obeticholic acid in a monocrotaline-induced pulmonary hypertension rat model.
Comeglio P, Filippi S, Sarchielli E, Morelli A, Cellai I, Corno C, Adorini L, Vannelli GB, Maggi M, Vignozzi L
J Endocrinol Invest, 42(8):951-965, 23 Jan 2019
Cited by: 6 articles | PMID: 30674010
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The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma.
Di Matteo S, Nevi L, Costantini D, Overi D, Carpino G, Safarikia S, Giulitti F, Napoletano C, Manzi E, De Rose AM, Melandro F, Bragazzi M, Berloco PB, Giuliante F, Grazi G, Giorgi A, Cardinale V, Adorini L, Gaudio E, Alvaro D
PLoS One, 14(1):e0210077, 24 Jan 2019
Cited by: 19 articles | PMID: 30677052 | PMCID: PMC6345424
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FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice.
Iracheta-Vellve A, Calenda CD, Petrasek J, Ambade A, Kodys K, Adorini L, Szabo G
Hepatol Commun, 2(11):1379-1391, 15 Oct 2018
Cited by: 42 articles | PMID: 30411084 | PMCID: PMC6211332
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FXR-Dependent Modulation of the Human Small Intestinal Microbiome by the Bile Acid Derivative Obeticholic Acid.
Friedman ES, Li Y, Shen TD, Jiang J, Chau L, Adorini L, Babakhani F, Edwards J, Shapiro D, Zhao C, Carr RM, Bittinger K, Li H, Wu GD
Gastroenterology, 155(6):1741-1752.e5, 23 Aug 2018
Cited by: 63 articles | PMID: 30144429 | PMCID: PMC6279623
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TGR5 activation induces cytoprotective changes in the heart and improves myocardial adaptability to physiologic, inotropic, and pressure-induced stress in mice.
Eblimit Z, Thevananther S, Karpen SJ, Taegtmeyer H, Moore DD, Adorini L, Penny DJ, Desai MS
Cardiovasc Ther, 36(5):e12462, 22 Aug 2018
Cited by: 35 articles | PMID: 30070769 | PMCID: PMC6800140
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Therapeutic effects of obeticholic acid (OCA) treatment in a bleomycin-induced pulmonary fibrosis rat model.
Comeglio P, Filippi S, Sarchielli E, Morelli A, Cellai I, Corno C, Pini A, Adorini L, Vannelli GB, Maggi M, Vignozzi L
J Endocrinol Invest, 42(3):283-294, 19 Jun 2018
Cited by: 8 articles | PMID: 29923060
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