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Search life-sciences literature (45,100,050 articles, preprints and more)

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Structures of the human transcription factor brachyury offer insights into DNA recognition, and identify small molecule binders for the development of degraders for cancer therapy
Newman JA, Gavard AE, Imprachim N, Aitkenhead H, Sheppard HE, Clarke PA, Hossain MA, Temme L, Oh HJ, Wells CI, Davis-Gilbert ZW, Workman P, Gileadi O, Drewry DH
bioRxiv, 06 Jun 2024
Cited by: 0 articles | PPR: PPR863760
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Incidental Detection of Classical Galactosemia through Newborn Screening for Phenylketonuria: A 10-Year Retrospective Audit to Determine the Efficacy of This Approach.
Cantley NWP, Barski R, Kemp H, Hogg SL, Wu HYT, Bowron A, Collingwood C, Cundick J, Hart C, Shakespeare L, Preece MA, Aitkenhead H, Smith S, Carling RS, Moat SJ
Int J Neonatal Screen, 10(1):2, 22 Dec 2023
Cited by: 1 article | PMID: 38248630 | PMCID: PMC10801530
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Structural comparison of typical and atypical E2 pestivirus glycoproteins.
Aitkenhead H, Riedel C, Cowieson N, Rümenapf HT, Stuart DI, El Omari K
Structure, 32(3):273-281.e4, 03 Jan 2024
Cited by: 3 articles | PMID: 38176409
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Structure of Bovine CD46 Ectodomain.
Aitkenhead H, Stuart DI, El Omari K
Viruses, 15(7):1424, 23 Jun 2023
Cited by: 1 article | PMID: 37515111 | PMCID: PMC10385506
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Inaccuracies in plasma oxytocin extraction and enzyme immunoassay techniques.
Gan HW, Leeson C, Aitkenhead H, Dattani M
Compr Psychoneuroendocrinol, 15:100188, 08 Jun 2023
Cited by: 4 articles | PMID: 37360277 | PMCID: PMC10285453
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UK National audit of the measurement of ammonia.
Aitkenhead H
Ann Clin Biochem, 60(2):117-125, 17 Jan 2023
Cited by: 0 articles | PMID: 36604773
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Cross-sectional audit assessing the quality of dried bloodspot specimens received by UK metabolic biochemistry laboratories for the biochemical monitoring of individuals with Phenylketonuria.
Hogg SL, Carling RS, Cantley NW, Hamilton G, Goddard P, Aitkenhead H, Barski R, Collingwood C, Moat SJ, Kemp HJ
Ann Clin Biochem, 60(3):208-211, 10 Feb 2023
Cited by: 2 articles | PMID: 36762708
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A Single-Center, Observational Study of 607 Children and Young People Presenting With Differences of Sex Development (DSD).
Man E, Mushtaq I, Barnicoat A, Carmichael P, Hughes CR, Davies K, Aitkenhead H, Amin R, Buchanan CR, Cherian A, Costa NJ, Creighton SM, Duffy PG, Hewson E, Hindmarsh PC, Monzani LC, Peters CJ, Ransley PG, Smeulders N, [...] Achermann JC
J Endocr Soc, 7(1):bvac165, 28 Oct 2022
Cited by: 5 articles | PMID: 36419940 | PMCID: PMC9676112
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Establishing risk factors and outcomes for congenital hypothyroidism with gland in situ using population-based data linkage methods: study protocol.
Ruiz Nishiki M, Cabecinha M, Knowles R, Peters C, Aitkenhead H, Ifederu A, Schoenmakers N, Sebire NJ, Walker E, Hardelid P
BMJ Paediatr Open, 6(1):e001341, 01 Mar 2022
Cited by: 0 articles | PMID: 36053651 | PMCID: PMC8969044
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Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive close contacts
Ye M, Makola M, Newman JA, Fairhead M, Maclean E, Wright ND, Koekemoer L, Thompson A, Bezerra GA, Yi G, Li H, Rangel VL, Mamalis D, Aitkenhead H, Davis BG, Gilbert RJ, Duerr K, Gileadi O, von Delft F
bioRxiv, 26 Jul 2022
Cited by: 0 articles | PPR: PPR524612
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Atypical Porcine Pestiviruses: Relationships and Conserved Structural Features.
Riedel C, Aitkenhead H, El Omari K, Rümenapf T
Viruses, 13(5):760, 26 Apr 2021
Cited by: 5 articles | PMID: 33926056 | PMCID: PMC8146772
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The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity.
Newman JA, Aitkenhead H, Gavard AE, Rota IA, Handel AE, Hollander GA, Gileadi O
J Biol Chem, 295(10):2948-2958, 30 Dec 2019
Cited by: 14 articles | PMID: 31914405 | PMCID: PMC7062188
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Free 25-hydroxyvitamin-D concentrations are lower in children with renal transplant compared with chronic kidney disease.
Preka E, Wan M, Price KL, Long DA, Aitkenhead H, Shroff R
Pediatr Nephrol, 35(6):1069-1079, 22 Jan 2020
Cited by: 3 articles | PMID: 31970483 | PMCID: PMC7184055
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A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.
Lim M, Newman JA, Williams HL, Masino L, Aitkenhead H, Gravard AE, Gileadi O, Svejstrup JQ
Structure, 27(8):1316-1325.e6, 13 Jun 2019
Cited by: 16 articles | PMID: 31204252 | PMCID: PMC6688830
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Effects of Hemodiafiltration versus Conventional Hemodialysis in Children with ESKD: The HDF, Heart and Height Study.
Shroff R, Smith C, Ranchin B, Bayazit AK, Stefanidis CJ, Askiti V, Azukaitis K, Canpolat N, Ağbaş A, Aitkenhead H, Anarat A, Aoun B, Aofolaju D, Bakkaloglu SA, Bhowruth D, Borzych-Dużałka D, Bulut IK, Büscher R, Deanfield J, [...] Schaefer F
J Am Soc Nephrol, 30(4):678-691, 07 Mar 2019
Cited by: 30 articles | PMID: 30846560 | PMCID: PMC6442347
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The structural basis for forkhead box family specificity revealed by the crystal structure of human FOXN1 in complex with DNA
Newman JA, Aitkenhead H, Gravard A, Rota IA, Handel AE, Hollander GA, Gileadi O
bioRxiv, 26 Sep 2018
Cited by: 0 articles | PPR: PPR57109
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A Ubiquitin-Binding Domain that Does Not Bind Ubiquitin
Lim M, Newman JA, Williams HL, Aitkenhead H, Gileadi O, Svejstrup JQ
bioRxiv, 24 Jul 2018
Cited by: 0 articles | PPR: PPR45840
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Effects of nutritional vitamin D supplementation on markers of bone and mineral metabolism in children with chronic kidney disease.
Lerch C, Shroff R, Wan M, Rees L, Aitkenhead H, Kaplan Bulut I, Thurn D, Karabay Bayazit A, Niemirska A, Canpolat N, Duzova A, Azukaitis K, Yilmaz E, Yalcinkaya F, Harambat J, Kiyak A, Alpay H, Habbig S, Zaloszyc A, [...] ESPN CKD-MBD working group
Nephrol Dial Transplant, 33(12):2208-2217, 01 Dec 2018
Cited by: 16 articles | PMID: 29481636
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Hemodiafiltration is associated with reduced inflammation, oxidative stress and improved endothelial risk profile compared to high-flux hemodialysis in children.
Ağbaş A, Canpolat N, Çalışkan S, Yılmaz A, Ekmekçi H, Mayes M, Aitkenhead H, Schaefer F, Sever L, Shroff R
PLoS One, 13(6):e0198320, 18 Jun 2018
Cited by: 21 articles | PMID: 29912924 | PMCID: PMC6005477
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Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
Newman JA, Aitkenhead H, Savitsky P, Gileadi O
Nucleic Acids Res, 45(7):4231-4243, 01 Apr 2017
Cited by: 13 articles | PMID: 28100692 | PMCID: PMC5397160
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Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.
Vaz B, Popovic M, Newman JA, Fielden J, Aitkenhead H, Halder S, Singh AN, Vendrell I, Fischer R, Torrecilla I, Drobnitzky N, Freire R, Amor DJ, Lockhart PJ, Kessler BM, McKenna GW, Gileadi O, Ramadan K
Mol Cell, 64(4):704-719, 27 Oct 2016
Cited by: 139 articles | PMID: 27871366 | PMCID: PMC5128727
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Measuring Erythrocyte Thiopurine Methyltransferase Activity in Children-Is It Helpful?
Ma AL, Bale G, Aitkenhead H, Marks SD
J Pediatr, 179:216-218, 15 Sep 2016
Cited by: 2 articles | PMID: 27640357
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Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.
Newman JA, Cooper CDO, Aitkenhead H, Gileadi O
Structure, 23(12):2319-2330, 01 Dec 2015
Cited by: 57 articles | PMID: 26636256 | PMCID: PMC4671958
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Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Newman JA, Cooper CD, Roos AK, Aitkenhead H, Oppermann UC, Cho HJ, Osman R, Gileadi O
PLoS One, 11(2):e0148762, 24 Feb 2016
Cited by: 19 articles | PMID: 26910052 | PMCID: PMC4766014
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Normal 25-Hydroxyvitamin D Levels Are Associated with Less Proteinuria and Attenuate Renal Failure Progression in Children with CKD.
Shroff R, Aitkenhead H, Costa N, Trivelli A, Litwin M, Picca S, Anarat A, Sallay P, Ozaltin F, Zurowska A, Jankauskiene A, Montini G, Charbit M, Schaefer F, Wühl E, ESCAPE Trial Group
J Am Soc Nephrol, 27(1):314-322, 11 Jun 2015
Cited by: 26 articles | PMID: 26069294 | PMCID: PMC4696567
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