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Search life-sciences literature (45,103,589 articles, preprints and more)

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Platelet PI3Kβ regulates breast cancer metastasis
Graff RC, Haimowitz A, Aguilan JT, Levine A, Zhang J, Yuan W, Roose-Girma M, Seshagiri S, Porcelli SA, Gamble MJ, Sidoli S, Bresnick AR, Backer JM
bioRxiv, 14 Sep 2024
Cited by: 0 articles | PPR: PPR911534
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Macropinocytosis: mechanisms and regulation.
Salloum G, Bresnick AR, Backer JM
Biochem J, 480(5):335-362, 01 Mar 2023
Cited by: 17 articles | PMID: 36920093
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PIP₃ abundance overcomes PI3K signaling selectivity in invadopodia.
Jakubik CT, Weckerly CC, Hammond GRV, Bresnick AR, Backer JM
FEBS Lett, 596(4):417-426, 12 Jan 2022
Cited by: 0 articles | PMID: 34990021 | PMCID: PMC8885911
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Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract.
Maddala R, Gao J, Mathias RT, Lewis TR, Arshavsky VY, Levine A, Backer JM, Bresnick AR, Rao PV
Sci Rep, 11(1):2203, 26 Jan 2021
Cited by: 11 articles | PMID: 33500475 | PMCID: PMC7838418
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, [...] Tong CK
Autophagy, 17(1):1-382, 01 Jan 2021
Cited by: 1148 articles | PMID: 33634751 | PMCID: PMC7996087
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Imaging Early-Stage Metastases Using an ¹⁸F-Labeled VEGFR-1-Specific Single Chain VEGF Mutant.
Mason CA, Carter LM, Mandleywala K, de Souza Franca PD, Meyer JP, Mamun T, Backer JM, Backer MV, Reiner T, Lewis JS
Mol Imaging Biol, 23(3):340-349, 06 Nov 2020
Cited by: 3 articles | PMID: 33156495 | PMCID: PMC8099920
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PI3Kβ is selectively required for growth factor-stimulated macropinocytosis.
Salloum G, Jakubik CT, Erami Z, Heitz SD, Bresnick AR, Backer JM
J Cell Sci, 132(16):jcs231639, 16 Aug 2019
Cited by: 12 articles | PMID: 31409694 | PMCID: PMC6737911
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PI3Kβ links integrin activation and PI(3,4)P₂ production during invadopodial maturation.
Erami Z, Heitz S, Bresnick AR, Backer JM
Mol Biol Cell, 30(18):2367-2376, 18 Jul 2019
Cited by: 5 articles | PMID: 31318314 | PMCID: PMC6741064
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PI3Kβ-A Versatile Transducer for GPCR, RTK, and Small GTPase Signaling.
Bresnick AR, Backer JM
Endocrinology, 160(3):536-555, 01 Mar 2019
Cited by: 19 articles | PMID: 30601996 | PMCID: PMC6375709
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A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion.
Heitz SD, Hamelin DJ, Hoffmann RM, Greenberg N, Salloum G, Erami Z, Khalil BD, Shymanets A, Steidle EA, Gong GQ, Nürnberg B, Burke JE, Flanagan JU, Bresnick AR, Backer JM
J Biol Chem, 294(12):4621-4633, 18 Jan 2019
Cited by: 7 articles | PMID: 30659094 | PMCID: PMC6433078
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Targeting Fluorescent Nanodiamonds to Vascular Endothelial Growth Factor Receptors in Tumor.
Torelli MD, Rickard AG, Backer MV, Filonov DS, Nunn NA, Kinev AV, Backer JM, Palmer GM, Shenderova OA
Bioconjug Chem, 30(3):604-613, 31 Jan 2019
Cited by: 12 articles | PMID: 30633508 | PMCID: PMC7605622
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Myosin-IIA heavy chain phosphorylation on S1943 regulates tumor metastasis.
Norwood Toro LE, Wang Y, Condeelis JS, Jones JG, Backer JM, Bresnick AR
Exp Cell Res, 370(2):273-282, 25 Jun 2018
Cited by: 8 articles | PMID: 29953877 | PMCID: PMC6117828
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Selective Imaging of Vascular Endothelial Growth Factor Receptor-1 and Receptor-2 in Atherosclerotic Lesions in Diabetic and Non-diabetic ApoE^-/- Mice.
Tekabe Y, Johnson LL, Rodriquez K, Li Q, Backer M, Backer JM
Mol Imaging Biol, 20(1):85-93, 01 Feb 2018
Cited by: 9 articles | PMID: 28421362
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S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms.
Dulyaninova NG, Ruiz PD, Gamble MJ, Backer JM, Bresnick AR
Mol Biol Cell, 29(5):632-642, 27 Dec 2017
Cited by: 15 articles | PMID: 29282275 | PMCID: PMC6004585
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Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.
Bilanges B, Alliouachene S, Pearce W, Morelli D, Szabadkai G, Chung YL, Chicanne G, Valet C, Hill JM, Voshol PJ, Collinson L, Peddie C, Ali K, Ghazaly E, Rajeeve V, Trichas G, Srinivas S, Chaussade C, Salamon RS, [...] Vanhaesebroeck B
Nat Commun, 8(1):1804, 27 Nov 2017
Cited by: 41 articles | PMID: 29180704 | PMCID: PMC5703854
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Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.
Erami Z, Khalil BD, Salloum G, Yao Y, LoPiccolo J, Shymanets A, Nürnberg B, Bresnick AR, Backer JM
Biochem J, 474(23):3903-3914, 16 Nov 2017
Cited by: 14 articles | PMID: 29046393 | PMCID: PMC5858185
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A "Dock and Lock" Approach to Preparation of Targeted Liposomes.
Backer MV, Backer JM
Methods Mol Biol, 1522:83-92, 01 Jan 2017
Cited by: 0 articles | PMID: 27837532
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The intricate regulation and complex functions of the Class III phosphoinositide 3-kinase Vps34.
Backer JM
Biochem J, 473(15):2251-2271, 01 Aug 2016
Cited by: 117 articles | PMID: 27470591
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Selective Imaging of VEGFR-1 and VEGFR-2 Using 89Zr-Labeled Single-Chain VEGF Mutants.
Meyer JP, Edwards KJ, Kozlowski P, Backer MV, Backer JM, Lewis JS
J Nucl Med, 57(11):1811-1816, 07 Jul 2016
Cited by: 16 articles | PMID: 27390161 | PMCID: PMC5095510
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Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells.
Houslay DM, Anderson KE, Chessa T, Kulkarni S, Fritsch R, Downward J, Backer JM, Stephens LR, Hawkins PT
Sci Signal, 9(441):ra82, 16 Aug 2016
Cited by: 35 articles | PMID: 27531651 | PMCID: PMC5417692
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GPCR Signaling Mediates Tumor Metastasis via PI3Kβ.
Khalil BD, Hsueh C, Cao Y, Abi Saab WF, Wang Y, Condeelis JS, Bresnick AR, Backer JM
Cancer Res, 76(10):2944-2953, 24 Mar 2016
Cited by: 38 articles | PMID: 27013201 | PMCID: PMC4915222
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Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy.
Rusckowski M, Wang Y, Blankenberg FG, Levashova Z, Backer MV, Backer JM
EJNMMI Res, 6(1):4, 16 Jan 2016
Cited by: 8 articles | PMID: 26780081 | PMCID: PMC4715132
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Identification of Atypical Peri-Nuclear Multivesicular Bodies in Oxidative and Glycolytic Skeletal Muscle of Aged and Pompe's Disease Mouse Models.
Neel BA, Zong H, Backer JM, Pessin JE
Front Physiol, 6:393, 21 Dec 2015
Cited by: 2 articles | PMID: 26733885 | PMCID: PMC4685069
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, [...] Zughaier SM
Autophagy, 12(1):1-222, 01 Jan 2016
Cited by: 3223 articles | PMID: 26799652 | PMCID: PMC4835977
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Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity.
Alliouachene S, Bilanges B, Chicanne G, Anderson KE, Pearce W, Ali K, Valet C, Posor Y, Low PC, Chaussade C, Scudamore CL, Salamon RS, Backer JM, Stephens L, Hawkins PT, Payrastre B, Vanhaesebroeck B
Cell Rep, 13(9):1881-1894, 19 Nov 2015
Cited by: 43 articles | PMID: 26655903 | PMCID: PMC4675724
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