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Search life-sciences literature (45,100,050 articles, preprints and more)

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The role of mesenchymal cells in cholangiocarcinoma.
Sueca-Comes M, Rusu EC, Ashworth JC, Collier P, Probert C, Ritchie A, Meakin M, Mongan NP, Egbuniwe IU, Andersen JB, Bates DO, Grabowska AM
Dis Model Mech, dmm.050716, 04 Nov 2024
Cited by: 0 articles | PMID: 39492622
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Single-cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of WT1 kidney disease.
Chandler JC, Jafree DJ, Malik S, Pomeranz G, Ball M, Kolatsi-Joannou M, Piapi A, Mason WJ, Benest AV, Bates DO, Letunovska A, Al-Saadi R, Rabant M, Boyer O, Pritchard-Jones K, Winyard PJ, Mason AS, Woolf AS, Waters AM, Long DA
J Pathol, 264(2):212-227, 23 Aug 2024
Cited by: 0 articles | PMID: 39177649
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The splicing factor kinase SRPK1 is a therapeutic target for Peripheral Vascular Disease
Bhalla SR, Wahid M, Amartey J, Riu F, Gao Y, Agrawal J, Lynch AP, Machado MJ, Hawtrey T, Kikuchi R, Green KR, Teboul L, Allen C, Blackley Z, Rajaji K, Marsden D, Batson J, Harper SJ, Oltean S, [...] Bates DO
bioRxiv, 22 Apr 2024
Cited by: 0 articles | PPR: PPR841279
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Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes.
Gamez M, Elhegni HE, Fawaz S, Ho KH, Campbell NW, Copland DA, Onions KL, Butler MJ, Wasson EJ, Crompton M, Ramnath RD, Qiu Y, Yamaguchi Y, Arkill KP, Bates DO, Turnbull JE, Zubkova OV, Welsh GI, Atan D, [...] Foster RR
Cardiovasc Diabetol, 23(1):50, 01 Feb 2024
Cited by: 2 articles | PMID: 38302978 | PMCID: PMC10835837
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Therapeutic Implications of Ceritinib in Cholangiocarcinoma beyond ALK Expression and Mutation.
Myint KZ, Balasubramanian B, Venkatraman S, Phimsen S, Sripramote S, Jantra J, Choeiphuk C, Mingphruedhi S, Muangkaew P, Rungsakulkij N, Tangtawee P, Suragul W, Farquharson WV, Wongprasert K, Chutipongtanate S, Sanvarinda P, Ponpuak M, Poungvarin N, Janvilisri T, [...] Tohtong R
Pharmaceuticals (Basel), 17(2):197, 02 Feb 2024
Cited by: 0 articles | PMID: 38399413 | PMCID: PMC10892566
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Angiotensin II type 1 receptor activation facilitates pain hypersensitivity via dorsal horn pericyte mediated vasoconstriction
Hardowar LD, Sheavyn M, McTernan PG, Bates DO, Hulse RP
bioRxiv, 13 Dec 2023
Cited by: 0 articles | PPR: PPR773724
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CP-673451, a Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitor, Induces Apoptosis in <i>Opisthorchis viverrini</i>-Associated Cholangiocarcinoma via Nrf2 Suppression and Enhanced ROS.
Duangdara J, Boonsri B, Sayinta A, Supradit K, Thintharua P, Kumkate S, Suriyonplengsaeng C, Larbcharoensub N, Mingphruedhi S, Rungsakulkij N, Muangkaew P, Tangtawee P, Vassanasiri W, Suragul W, Janvilisri T, Tohtong R, Bates DO, Wongprasert K
Pharmaceuticals (Basel), 17(1):9, 20 Dec 2023
Cited by: 0 articles | PMID: 38275995 | PMCID: PMC10821224
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Preclinical evidence for anaplastic lymphoma kinase inhibitors as novel therapeutic treatments for cholangiocarcinoma.
Myint KZ, Sueca-Comes M, Collier P, Balasubramanian B, Venkatraman S, Gordan J, Zaitoun AM, Mukherjee A, Arora A, Larbcharoensub N, Suriyonplengsaeng C, Wongprasert K, Janvilisri T, Gomez D, Grabowska AM, Tohtong R, Bates DO, Yacqub-Usman K
Front Oncol, 13:1184900, 07 Dec 2023
Cited by: 1 article | PMID: 38144528 | PMCID: PMC10748508
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Targeting alternative splicing as a new cancer immunotherapy-phosphorylation of serine arginine-rich splicing factor (SRSF1) by SR protein kinase 1 (SRPK1) regulates alternative splicing of PD1 to generate a soluble antagonistic isoform that prevents T cell exhaustion.
Wahid M, Pratoomthai B, Egbuniwe IU, Evans HR, Babaei-Jadidi R, Amartey JO, Erdelyi V, Yacqub-Usman K, Jackson AM, Morris JC, Patel PM, Bates DO
Cancer Immunol Immunother, 72(12):4001-4014, 16 Nov 2023
Cited by: 7 articles | PMID: 37973660 | PMCID: PMC10700477
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Elevated PLAUR is observed in the airway epithelium of asthma patients and blocking improves barrier integrity.
Portelli MA, Bhaker S, Pang V, Bates DO, Johnson SR, Mazar AP, Shaw D, Brightling C, Sayers I
Clin Transl Allergy, 13(10):e12293, 01 Oct 2023
Cited by: 1 article | PMID: 37876037 | PMCID: PMC10542610
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Alternative Splicing Events and Their Clinical Significance in Colorectal Cancer: Targeted Therapeutic Opportunities.
Manabile MA, Hull R, Khanyile R, Molefi T, Damane BP, Mongan NP, Bates DO, Dlamini Z
Cancers (Basel), 15(15):3999, 07 Aug 2023
Cited by: 3 articles | PMID: 37568815 | PMCID: PMC10417810
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Vascular endothelial growth factor isoforms differentially protect neurons against neurotoxic events associated with Alzheimer's disease.
Alalwany RH, Hawtrey T, Morgan K, Morris JC, Donaldson LF, Bates DO
Front Mol Neurosci, 16:1181626, 27 Jun 2023
Cited by: 2 articles | PMID: 37456522 | PMCID: PMC10349181
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Measurement of solute permeability in the mouse spinal cord.
Lobo MEDV, Bates DO, Arkill KP, Hulse RP
J Neurosci Methods, 393:109880, 11 May 2023
Cited by: 0 articles | PMID: 37178727
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Targeting FGFRs Using PD173074 as a Novel Therapeutic Strategy in Cholangiocarcinoma.
Balasubramanian B, Yacqub-Usman K, Venkatraman S, Myint KZ, Juengsamarn J, Sarkhampee P, Lertsawatvicha N, Sripa J, Kuakpaetoon T, Suriyonplengsaeng C, Wongprasert K, Grabowska AM, Bates DO, Janvilisri T, Tohtong R
Cancers (Basel), 15(9):2528, 28 Apr 2023
Cited by: 0 articles | PMID: 37173994 | PMCID: PMC10177182
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Genomic Interplay between Neoneurogenesis and Neoangiogenesis in Carcinogenesis: Therapeutic Interventions.
Dlamini Z, Khanyile R, Molefi T, Damane BP, Bates DO, Hull R
Cancers (Basel), 15(6):1805, 16 Mar 2023
Cited by: 1 article | PMID: 36980690 | PMCID: PMC10046518
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Novel Approach to Measure Transepithelial Electrical Resistance in Intestinal Cells.
Marva G, Ünsal S, Benest AV, Bates DO, Ordóñez-Morán P
Methods Mol Biol, 2650:35-42, 01 Jan 2023
Cited by: 0 articles | PMID: 37310621
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Looking Under the Lamppost: The Search for New Cancer Targets in the Human Kinome.
Sueca-Comes M, Rusu EC, Grabowska AM, Bates DO
Pharmacol Rev, 74(4):1136-1145, 01 Oct 2022
Cited by: 1 article | PMID: 36180110
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Competing Endogenous RNA (ceRNA) Networks and Splicing Switches in Cervical Cancer: HPV Oncogenesis, Clinical Significance and Therapeutic Opportunities.
Basera A, Hull R, Demetriou D, Bates DO, Kaufmann AM, Dlamini Z, Marima R
Microorganisms, 10(9):1852, 16 Sep 2022
Cited by: 6 articles | PMID: 36144454 | PMCID: PMC9501168
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Inhibition of serine/arginine-rich protein kinase-1 (SRPK1) prevents cholangiocarcinoma cells induced angiogenesis.
Supradit K, Boonsri B, Duangdara J, Thitiphatphuvanon T, Suriyonplengsaeng C, Kangsamaksin T, Janvilisri T, Tohtong R, Yacqub-Usman K, Grabowska AM, Bates DO, Wongprasert K
Toxicol In Vitro, 82:105385, 11 May 2022
Cited by: 2 articles | PMID: 35568131
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Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts.
Sharpe BP, Hayden A, Manousopoulou A, Cowie A, Walker RC, Harrington J, Izadi F, Breininger SP, Gibson J, Pickering O, Jaynes E, Kyle E, Saunders JH, Parsons SL, Ritchie AA, Clarke PA, Collier P, Mongan NP, Bates DO, [...] Underwood TJ
Cell Rep Med, 3(6):100541, 01 Jun 2022
Cited by: 3 articles | PMID: 35732148 | PMCID: PMC9244979
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Hypoxia-induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain.
Da Vitoria Lobo ME, Weir N, Hardowar L, Al Ojaimi Y, Madden R, Gibson A, Bestall SM, Hirashima M, Schaffer CB, Donaldson LF, Bates DO, Hulse RP
Pain, 163(11):2264-2279, 29 Mar 2022
Cited by: 3 articles | PMID: 35353768 | PMCID: PMC9578530
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Serine-arginine-rich protein kinase-1 inhibition for the treatment of diabetic retinopathy.
Malhi NK, Allen CL, Stewart E, Horton KL, Riu F, Batson J, Amoaku W, Morris JC, Arkill KP, Bates DO
Am J Physiol Heart Circ Physiol, 322(6):H1014-H1027, 18 Mar 2022
Cited by: 5 articles | PMID: 35302878 | PMCID: PMC9109797
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Quantification of Angiogenesis in Laser Choroidal Neovascularization.
Green KR, Beazley-Long N, Lynch AP, Allen CL, Bates DO, Benest AV
Methods Mol Biol, 2441:223-231, 01 Jan 2022
Cited by: 0 articles | PMID: 35099740
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Noninvasive Measurement of Retinal Microvascular Permeability During Loss of Endothelial Quiescence.
Malhi NK, Bates DO, Arkill KP, Allen CL
Methods Mol Biol, 2441:135-156, 01 Jan 2022
Cited by: 0 articles | PMID: 35099734
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Measurement of Revascularization in the Hind Limb After Experimental Ischemia in Mice.
Bhalla SR, Riu F, Machado MJC, Bates DO
Methods Mol Biol, 2441:105-113, 01 Jan 2022
Cited by: 0 articles | PMID: 35099732
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