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Search life-sciences literature (45,104,145 articles, preprints and more)

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TMED inhibition suppresses cell surface PD-1 expression and overcomes T cell dysfunction.
Vredevoogd DW, Apriamashvili G, Levy PL, Sinha S, Huinen ZR, Visser NL, de Bruijn B, Boshuizen J, van Hal-van Veen SE, Ligtenberg MA, Bleijerveld OB, Lin CP, Díaz-Gómez J, Sánchez SD, Markovits E, Simon Nieto J, van Vliet A, Krijgsman O, Markel G, [...] Peeper DS
J Immunother Cancer, 12(11):e010145, 07 Nov 2024
Cited by: 0 articles | PMID: 39510795 | PMCID: PMC11552591
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Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness.
Lin CP, Levy PL, Alflen A, Apriamashvili G, Ligtenberg MA, Vredevoogd DW, Bleijerveld OB, Alkan F, Malka Y, Hoekman L, Markovits E, George A, Traets JJH, Krijgsman O, van Vliet A, Poźniak J, Pulido-Vicuña CA, de Bruijn B, van Hal-van Veen SE, [...] Peeper DS
Cancer Cell, 42(4):623-645.e10, 14 Mar 2024
Cited by: 0 articles | PMID: 38490212 | PMCID: PMC11003465
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Genetic Modification of Tumor-Infiltrating Lymphocytes, Peripheral T Cells, and T-Cell Model Cell Lines.
Weinstein-Marom H, Blokon-Kogan D, Levi-Mann M, Katzman C, Shalev S, Zaitsev M, Besser MJ, Shapira-Frommer R, Gross G, Itzhaki O, Nissim L
Methods Mol Biol, 2748:167-186, 01 Jan 2024
Cited by: 0 articles | PMID: 38070115
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Automated production of gene-modified chimeric antigen receptor T cells using the Cocoon Platform.
Trainor N, Purpura KA, Middleton K, Fargo K, Hails L, Vicentini-Hogan M, McRobie C, Daniels R, Densham P, Gardin P, Fouks M, Brayer H, Malka RG, Rodin A, Ogen T, Besser MJ, Smith T, Leonard D, Bryan A
Cytotherapy, 25(12):1349-1360, 09 Sep 2023
Cited by: 5 articles | PMID: 37690020
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MYC Induces Immunotherapy and IFNγ Resistance Through Downregulation of JAK2.
Markovits E, Harush O, Baruch EN, Shulman ED, Debby A, Itzhaki O, Anafi L, Danilevsky A, Shomron N, Ben-Betzalel G, Asher N, Shapira-Frommer R, Schachter J, Barshack I, Geiger T, Elkon R, Besser MJ, Markel G
Cancer Immunol Res, 11(7):909-924, 01 Jul 2023
Cited by: 1 article | PMID: 37074069
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Modulating the proliferative and cytotoxic properties of patient-derived TIL by a synthetic immune niche of immobilized CCL21 and ICAM1.
Yunger S, Geiger B, Friedman N, Besser MJ, Adutler-Lieber S
Front Oncol, 13:1116328, 03 Mar 2023
Cited by: 3 articles | PMID: 36937426 | PMCID: PMC10020329
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Mitochondrial augmentation of hematopoietic stem cells in children with single large-scale mitochondrial DNA deletion syndromes.
Jacoby E, Bar-Yosef O, Gruber N, Lahav E, Varda-Bloom N, Bolkier Y, Bar D, Blumkin MB, Barak S, Eisenstein E, Ahonniska-Assa J, Silberg T, Krasovsky T, Bar O, Erez N, Bielorai B, Golan H, Dekel B, Besser MJ, [...] Toren A
Sci Transl Med, 14(676):eabo3724, 21 Dec 2022
Cited by: 14 articles | PMID: 36542693
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Outcomes of first therapy after CD19-CAR-T treatment failure in large B-cell lymphoma.
Alarcon Tomas A, Fein JA, Fried S, Flynn JR, Devlin SM, Fingrut WB, Anagnostou T, Alperovich A, Shah N, Fraint E, Lin RJ, Scordo M, Batlevi CL, Besser MJ, Dahi PB, Danylesko I, Giralt S, Imber BS, Jacoby E, [...] Shouval R
Leukemia, 37(1):154-163, 05 Nov 2022
Cited by: 23 articles | PMID: 36335261 | PMCID: PMC9892211
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Impact of cryopreservation on CAR T production and clinical response.
Brezinger-Dayan K, Itzhaki O, Melnichenko J, Kubi A, Zeltzer LA, Jacoby E, Avigdor A, Shapira Frommer R, Besser MJ
Front Oncol, 12:1024362, 06 Oct 2022
Cited by: 7 articles | PMID: 36276077 | PMCID: PMC9582437
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Adenosine-Deaminase-Acting-on-RNA-1 Facilitates T-cell Migration toward Human Melanoma Cells.
Margolis N, Moalem H, Meirson T, Galore-Haskel G, Markovits E, Baruch EN, Vizel B, Yeffet A, Kanterman-Rifman J, Debby A, Besser MJ, Schachter J, Markel G
Cancer Immunol Res, 10(9):1127-1140, 01 Sep 2022
Cited by: 3 articles | PMID: 35731225
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Point-of-care CAR T-cell therapy as salvage strategy for out-of-specification tisagenlecleucel.
Fried S, Shouval R, Varda-Bloom N, Besser MJ, Yerushalmi R, Shem-Tov N, Danylesko I, Jacoby E, Teihman S, Itzhaki O, Fein JA, Kedmi M, Shimoni A, Nagler A, Avigdor A
Leuk Lymphoma, 63(14):3385-3393, 16 Sep 2022
Cited by: 3 articles | PMID: 36111694
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Modulating the proliferative and cytotoxic properties of human TIL by a synthetic immune niche of immobilized CCL21 and ICAM1
Yunger S, Geiger B, Friedman N, Besser MJ, Adutler-Lieber S
bioRxiv, 07 Jul 2022
Cited by: 0 articles | PPR: PPR515277
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Molecular and Functional Signatures Associated with CAR T Cell Exhaustion and Impaired Clinical Response in Patients with B Cell Malignancies.
Beider K, Itzhaki O, Schachter J, Grushchenko-Polaq AH, Voevoda-Dimenshtein V, Rosenberg E, Ostrovsky O, Devillers O, Shapira Frommer R, Zeltzer LA, Toren A, Jacoby E, Shimoni A, Avigdor A, Nagler A, Besser MJ
Cells, 11(7):1140, 28 Mar 2022
Cited by: 9 articles | PMID: 35406703 | PMCID: PMC8997745
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Parameters of long-term response with CD28-based CD19 chimaeric antigen receptor-modified T cells in children and young adults with B-acute lymphoblastic leukaemia.
Jacoby E, Bielorai B, Hutt D, Itzhaki O, Adam E, Bar D, Besser MJ, Toren A
Br J Haematol, 197(4):475-481, 27 Feb 2022
Cited by: 9 articles | PMID: 35224724
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Epigenetic Profiling and Response to CD19 Chimeric Antigen Receptor T-Cell Therapy in B-Cell Malignancies.
Garcia-Prieto CA, Villanueva L, Bueno-Costa A, Davalos V, González-Navarro EA, Juan M, Urbano-Ispizua Á, Delgado J, Ortiz-Maldonado V, Del Bufalo F, Locatelli F, Quintarelli C, Sinibaldi M, Soler M, Castro de Moura M, Ferrer G, Urdinguio RG, Fernandez AF, Fraga MF, [...] Esteller M
J Natl Cancer Inst, 114(3):436-445, 01 Mar 2022
Cited by: 22 articles | PMID: 34581788 | PMCID: PMC8902331
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Impact of TP53 Genomic Alterations in Large B-Cell Lymphoma Treated With CD19-Chimeric Antigen Receptor T-Cell Therapy.
Shouval R, Alarcon Tomas A, Fein JA, Flynn JR, Markovits E, Mayer S, Olaide Afuye A, Alperovich A, Anagnostou T, Besser MJ, Batlevi CL, Dahi PB, Devlin SM, Fingrut WB, Giralt SA, Lin RJ, Markel G, Salles G, Sauter CS, [...] Palomba ML
J Clin Oncol, 40(4):369-381, 03 Dec 2021
Cited by: 49 articles | PMID: 34860572 | PMCID: PMC8797602
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Identification of bacteria-derived HLA-bound peptides in melanoma.
Kalaora S, Nagler A, Nejman D, Alon M, Barbolin C, Barnea E, Ketelaars SLC, Cheng K, Vervier K, Shental N, Bussi Y, Rotkopf R, Levy R, Benedek G, Trabish S, Dadosh T, Levin-Zaidman S, Geller LT, Wang K, [...] Samuels Y
Nature, 592(7852):138-143, 17 Mar 2021
Cited by: 152 articles | PMID: 33731925 | PMCID: PMC9717498
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Characteristics and risk factors of infections following CD28-based CD19 CAR-T cells.
Wittmann Dayagi T, Sherman G, Bielorai B, Adam E, Besser MJ, Shimoni A, Nagler A, Toren A, Jacoby E, Avigdor A
Leuk Lymphoma, 62(7):1692-1701, 10 Feb 2021
Cited by: 14 articles | PMID: 33563059
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Genetic Modification of Tumor-Infiltrating Lymphocytes via Retroviral Transduction.
Weinstein-Marom H, Gross G, Levi M, Brayer H, Schachter J, Itzhaki O, Besser MJ
Front Immunol, 11:584148, 07 Jan 2021
Cited by: 1 article | PMID: 33488585 | PMCID: PMC7817656
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Comparison of non-myeloablative lymphodepleting preconditioning regimens in patients undergoing adoptive T cell therapy.
Nissani A, Lev-Ari S, Meirson T, Jacoby E, Asher N, Ben-Betzalel G, Itzhaki O, Shapira-Frommer R, Schachter J, Markel G, Besser MJ
J Immunother Cancer, 9(5):e001743, 01 May 2021
Cited by: 21 articles | PMID: 33990415 | PMCID: PMC8127974
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Immune imitation of tumor progression after anti-CD19 chimeric antigen receptor T cells treatment in aggressive B-cell lymphoma.
Danylesko I, Shouval R, Shem-Tov N, Yerushalmi R, Jacoby E, Besser MJ, Shimoni A, Davidson T, Beider K, Mevorach D, Fried S, Nagler A, Avigdor A
Bone Marrow Transplant, 56(5):1134-1143, 03 Dec 2020
Cited by: 13 articles | PMID: 33268830 | PMCID: PMC8113054
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microRNA expression patterns in tumor infiltrating lymphocytes are strongly associated with response to adoptive cell transfer therapy.
Galore-Haskel G, Greenberg E, Yahav I, Markovits E, Ortenberg R, Shapira-Fromer R, Itzhaki O, Schachter J, Besser MJ, Markel G
Cancer Immunol Immunother, 70(6):1541-1555, 17 Nov 2020
Cited by: 2 articles | PMID: 33201337 | PMCID: PMC10991936
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ADAR1 regulates melanoma cell invasiveness by controlling beta3-integrin via microRNA-30 family members.
Nemlich Y, Besser MJ, Schachter J, Markel G
Am J Cancer Res, 10(8):2677-2686, 01 Aug 2020
Cited by: 5 articles | PMID: 32905549 | PMCID: PMC7471345
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Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia.
Rozenbaum M, Meir A, Aharony Y, Itzhaki O, Schachter J, Bank I, Jacoby E, Besser MJ
Front Immunol, 11:1347, 02 Jul 2020
Cited by: 115 articles | PMID: 32714329 | PMCID: PMC7343910
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Feasibility of leukapheresis for CAR T-cell production in heavily pre-treated pediatric patients.
Hutt D, Bielorai B, Baturov B, Z'orbinski I, Ilin N, Adam E, Itzhaki O, Besser MJ, Toren A, Jacoby E
Transfus Apher Sci, 59(4):102769, 25 Apr 2020
Cited by: 10 articles | PMID: 32414613
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1-25 of 88 results

1 2 3 Next ...

Search life-sciences literature (45,104,145 articles, preprints and more)

Search results

TMED inhibition suppresses cell surface PD-1 expression and overcomes T cell dysfunction.

Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness.

Genetic Modification of Tumor-Infiltrating Lymphocytes, Peripheral T Cells, and T-Cell Model Cell Lines.

Automated production of gene-modified chimeric antigen receptor T cells using the Cocoon Platform.

MYC Induces Immunotherapy and IFNγ Resistance Through Downregulation of JAK2.

Modulating the proliferative and cytotoxic properties of patient-derived TIL by a synthetic immune niche of immobilized CCL21 and ICAM1.

Mitochondrial augmentation of hematopoietic stem cells in children with single large-scale mitochondrial DNA deletion syndromes.

Outcomes of first therapy after CD19-CAR-T treatment failure in large B-cell lymphoma.

Impact of cryopreservation on CAR T production and clinical response.

Adenosine-Deaminase-Acting-on-RNA-1 Facilitates T-cell Migration toward Human Melanoma Cells.

Point-of-care CAR T-cell therapy as salvage strategy for out-of-specification tisagenlecleucel.

Modulating the proliferative and cytotoxic properties of human TIL by a synthetic immune niche of immobilized CCL21 and ICAM1

Molecular and Functional Signatures Associated with CAR T Cell Exhaustion and Impaired Clinical Response in Patients with B Cell Malignancies.

Parameters of long-term response with CD28-based CD19 chimaeric antigen receptor-modified T cells in children and young adults with B-acute lymphoblastic leukaemia.

Epigenetic Profiling and Response to CD19 Chimeric Antigen Receptor T-Cell Therapy in B-Cell Malignancies.

Impact of TP53 Genomic Alterations in Large B-Cell Lymphoma Treated With CD19-Chimeric Antigen Receptor T-Cell Therapy.

Identification of bacteria-derived HLA-bound peptides in melanoma.

Characteristics and risk factors of infections following CD28-based CD19 CAR-T cells.

Genetic Modification of Tumor-Infiltrating Lymphocytes via Retroviral Transduction.

Comparison of non-myeloablative lymphodepleting preconditioning regimens in patients undergoing adoptive T cell therapy.

Immune imitation of tumor progression after anti-CD19 chimeric antigen receptor T cells treatment in aggressive B-cell lymphoma.

microRNA expression patterns in tumor infiltrating lymphocytes are strongly associated with response to adoptive cell transfer therapy.

ADAR1 regulates melanoma cell invasiveness by controlling beta3-integrin via microRNA-30 family members.

Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia.

Feasibility of leukapheresis for CAR T-cell production in heavily pre-treated pediatric patients.

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