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Search life-sciences literature (45,100,050 articles, preprints and more)

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Publisher Correction: Novel immunotherapeutics against LGR5 to target multiple cancer types.
Chen HC, Mueller N, Stott K, Kapeni C, Rivers E, Sauer CM, Beke F, Walsh SJ, Ashman N, O'Brien L, Rafati Fard A, Ghodsinia A, Li C, Joud F, Giger O, Zlobec I, Olan I, Aitken SJ, Hoare M, [...] de la Roche M
EMBO Mol Med, 16(11):3026, 01 Nov 2024
Cited by: 0 articles | PMID: 39322863 | PMCID: PMC11555075
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Immunological and molecular features of the tumor microenvironment of long-term survivors of ovarian cancer.
Nelson BH, Hamilton PT, Phung MT, Milne K, Harris B, Thornton S, Stevens DL, Kalaria S, Singh K, Laumont CM, Moss E, Alimujiang A, Meagher NS, Bolithon A, Fereday S, Kennedy CJ, Hendley J, Ariyaratne D, Alsop K, [...] Pearce CL
J Clin Invest, e179501, 29 Oct 2024
Cited by: 0 articles | PMID: 39470729
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PTEN Loss Shapes Macrophage Dynamics in High-Grade Serous Ovarian Carcinoma.
Spear S, Le Saux O, Mirza HB, Iyer N, Tyson K, Grundland Freile F, Walton JB, Woodman C, Jarvis S, Ennis DP, Aguirre Hernandez C, Xu Y, Spiliopoulou P, Brenton JD, Costa-Pereira AP, Cook DP, Vanderhyden BC, Keun HC, Triantafyllou E, [...] McNeish IA
Cancer Res, 84(22):3772-3787, 01 Nov 2024
Cited by: 0 articles | PMID: 39186679 | PMCID: PMC7616669
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AUGMENT: a framework for robust assessment of the clinical utility of segmentation algorithms
McCague C, Buddenkotte T, Escudero Sanchez L, Hulse D, Pintican R, Rundo L, AUGMENT study team, Brenton JD, Couturier D, Öktem O, Woitek R, Schönlieb C, Sala E, Crispin Ortuzar M
medRxiv, 23 Sep 2024
Cited by: 0 articles | PPR: PPR914404
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Clinical validation of a DNA methylation biomarker to predict overall survival of relapsed ovarian cancer patients
Habiburrahman M, Masrour N, Patel N, Piskorz AM, Brown R, Brenton JD, McNeish IA, Flanagan JM
medRxiv, 19 Sep 2024
Cited by: 0 articles | PPR: PPR912209
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Primary culture of high grade serous ovarian cancer cells, selection and derivation of three cell lines
Brenton JD, Vias M, Sauer CM, Funingana G, Piskorz AM, Moore E, Chilamakuri C, Hall D, Goranova T, Van Oudenhove E, Earl HM, Goldlust I
bioRxiv, 19 Aug 2024
Cited by: 0 articles | PPR: PPR897915
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British Gynaecological Cancer Society/British Association of Gynaecological Pathology consensus for genetic testing in epithelial ovarian cancer in the United Kingdom.
Leung EY, Nicum S, Morrison J, Brenton JD, Funingana IG, Morgan RD, Ghaem-Maghami S, Miles T, Manchanda R, Bowen R, Andreou A, Loughborough W, Freeman S, Gajjar K, Coleridge S, Jimenez-Linan M, Balega J, Frost J, Keightley A, [...] Ganesan R
Int J Gynecol Cancer, 34(9):1334-1343, 02 Sep 2024
Cited by: 0 articles | PMID: 39222974
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Novel immunotherapeutics against LGR5 to target multiple cancer types.
Chen HC, Mueller N, Stott K, Kapeni C, Rivers E, Sauer CM, Beke F, Walsh SJ, Ashman N, O'Brien L, Rafati Fard A, Ghodsinia A, Li C, Joud F, Giger O, Zlobec I, Olan I, Aitken SJ, Hoare M, [...] de la Roche M
EMBO Mol Med, 16(9):2233-2261, 21 Aug 2024
Cited by: 0 articles | PMID: 39169164 | PMCID: PMC11393416
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Concurrent RB1 Loss and BRCA Deficiency Predicts Enhanced Immunologic Response and Long-term Survival in Tubo-ovarian High-grade Serous Carcinoma.
Saner FAM, Takahashi K, Budden T, Pandey A, Ariyaratne D, Zwimpfer TA, Meagher NS, Fereday S, Twomey L, Pishas KI, Hoang T, Bolithon A, Traficante N, Australian Ovarian Cancer Study Group, Alsop K, Christie EL, Kang EY, Nelson GS, Ghatage P, [...] Garsed DW
Clin Cancer Res, 30(16):3481-3498, 01 Aug 2024
Cited by: 0 articles | PMID: 38837893 | PMCID: PMC11325151
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Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions.
Dareng EO, Coetzee SG, Tyrer JP, Peng PC, Rosenow W, Chen S, Davis BD, Dezem FS, Seo JH, Nameki R, Reyes AL, Aben KKH, Anton-Culver H, Antonenkova NN, Aravantinos G, Bandera EV, Beane Freeman LE, Beckmann MW, Beeghly-Fadiel A, [...] Gayther SA
Am J Hum Genet, 111(6):1061-1083, 08 May 2024
Cited by: 3 articles | PMID: 38723632
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Exome sequencing identifiesHELBas a novel susceptibility gene for non-mucinous, non-high-grade-serous epithelial ovarian cancer
Dicks EM, Tyrer JP, Ezquina S, Jones M, Baierl J, Peng P, Diaz M, Goode E, Winham SJ, Dörk T, Van Gorp T, De Fazio A, Bowtell D, Odunsi K, Moysich K, Pavanello M, Campbell I, Brenton JD, Ramus SJ, [...] Pharoah PDP
medRxiv, 03 Apr 2024
Cited by: 0 articles | PPR: PPR831595
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Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk
Barnes DR, Tyrer JP, Dennis J, Leslie G, Bolla MK, Lush M, Aeilts AM, Aittomäki K, Andrieu N, Andrulis IL, Anton-Culver H, Arason A, Arun BK, Balmaña J, Bandera EV, Barkardottir RB, Berger LP, Berrington de Gonzalez A, Berthet P, [...] Pharoah PD
medRxiv, 04 Mar 2024
Cited by: 0 articles | PPR: PPR816124
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scAbsolute: measuring single-cell ploidy and replication status.
Schneider MP, Cullen AE, Pangonyte J, Skelton J, Major H, Van Oudenhove E, Garcia MJ, Chaves Urbano B, Piskorz AM, Brenton JD, Macintyre G, Markowetz F
Genome Biol, 25(1):62, 04 Mar 2024
Cited by: 4 articles | PMID: 38438920
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Deep learning-based segmentation of multisite disease in ovarian cancer.
Buddenkotte T, Rundo L, Woitek R, Escudero Sanchez L, Beer L, Crispin-Ortuzar M, Etmann C, Mukherjee S, Bura V, McCague C, Sahin H, Pintican R, Zerunian M, Allajbeu I, Singh N, Sahdev A, Havrilesky L, Cohn DE, Bateman NW, [...] Schönlieb CB
Eur Radiol Exp, 7(1):77, 07 Dec 2023
Cited by: 2 articles | PMID: 38057616 | PMCID: PMC10700248
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Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment.
Neilson LJ, Cartwright D, Risteli M, Jokinen EM, McGarry L, Sandvik T, Nikolatou K, Hodge K, Atkinson S, Vias M, Kay EJ, Brenton JD, Carlin LM, Bryant DM, Salo T, Zanivan S
Matrix Biol Plus, 19-20:100136, 22 Nov 2023
Cited by: 0 articles | PMID: 38223308 | PMCID: PMC10784634
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Concurrent RB1 loss andBRCA-deficiency predicts enhanced immunological response and long-term survival in tubo-ovarian high-grade serous carcinoma
Saner FAM, Takahashi K, Budden T, Pandey A, Ariyaratne D, Zwimpfer TA, Meagher NS, Fereday S, Twomey L, Pishas KI, Hoang T, Bolithon A, Traficante N, Alsop K, Christie EL, Kang E, Nelson GS, Ghatage P, Lee C, [...] Garsed DW
medRxiv, 10 Nov 2023
Cited by: 0 articles | PPR: PPR757426
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Integrated radiogenomics models predict response to neoadjuvant chemotherapy in high grade serous ovarian cancer.
Crispin-Ortuzar M, Woitek R, Reinius MAV, Moore E, Beer L, Bura V, Rundo L, McCague C, Ursprung S, Escudero Sanchez L, Martin-Gonzalez P, Mouliere F, Chandrananda D, Morris J, Goranova T, Piskorz AM, Singh N, Sahdev A, Pintican R, [...] Brenton JD
Nat Commun, 14(1):6756, 24 Oct 2023
Cited by: 5 articles | PMID: 37875466 | PMCID: PMC10598212
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Molecular landscape and functional characterization of centrosome amplification in ovarian cancer.
Sauer CM, Hall JA, Couturier DL, Bradley T, Piskorz AM, Griffiths J, Sawle A, Eldridge MD, Smith P, Hosking K, Reinius MAV, Morrill Gavarró L, Mes-Masson AM, Ennis D, Millan D, Hoyle A, McNeish IA, Jimenez-Linan M, Martins FC, [...] Brenton JD
Nat Commun, 14(1):6505, 16 Oct 2023
Cited by: 3 articles | PMID: 37845213 | PMCID: PMC10579337
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Author Correction: The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma.
Smith P, Bradley T, Gavarró LM, Goranova T, Ennis DP, Mirza HB, De Silva D, Piskorz AM, Sauer CM, Al-Khalidi S, Funingana IG, Reinius MAV, Giannone G, Lewsley LA, Stobo J, McQueen J, Bryson G, Eldridge M, BriTROC Investigators, [...] McNeish IA
Nat Commun, 14(1):5992, 26 Sep 2023
Cited by: 0 articles | PMID: 37752102 | PMCID: PMC10522588
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Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study.
Morgan RD, Clamp AR, Barnes BM, Timms K, Schlecht H, Yarram-Smith L, Wallis Y, Valganon-Petrizan M, MacMahon S, White R, Morgan S, McKenna S, Hudson E, Tookman L, George A, Manchanda R, Sundar SS, Nicum S, Brenton JD, [...] Jayson GC
Int J Gynecol Cancer, 33(8):1253-1259, 07 Aug 2023
Cited by: 5 articles | PMID: 37072323
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Heme oxygenase-1 expressing omental macrophages as a therapeutic target in ovarian high grade serous carcinoma
Spear S, Le Saux O, Mirza HB, Tyson K, Bickel J, Freile FG, Siskos AP, Balcells C, Walton JB, Woodman C, Ennis DP, Iyer N, Hernandez CA, Xu Y, Spiliopoulou P, Brenton JD, Costa-Pereira AP, Keun HC, Triantafyllou E, [...] McNeish IA
bioRxiv, 19 Jul 2023
Cited by: 0 articles | PPR: PPR693959
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The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma.
Smith P, Bradley T, Gavarró LM, Goranova T, Ennis DP, Mirza HB, De Silva D, Piskorz AM, Sauer CM, Al-Khalidi S, Funingana IG, Reinius MAV, Giannone G, Lewsley LA, Stobo J, McQueen J, Bryson G, Eldridge M, BriTROC Investigators, [...] McNeish IA
Nat Commun, 14(1):4387, 20 Jul 2023
Cited by: 9 articles | PMID: 37474499 | PMCID: PMC10359414
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Identification of Tissue-Resident Natural Killer and T Lymphocytes with Anti-Tumor Properties in Ascites of Ovarian Cancer Patients.
Bernson E, Huhn O, Karlsson V, Hawkes D, Lycke M, Cazzetta V, Mikulak J, Hall J, Piskorz AM, Portuesi R, Vitobello D, Fiamengo B, Siesto G, Horowitz A, Ghadially H, Mavilio D, Brenton JD, Sundfeldt K, Colucci F
Cancers (Basel), 15(13):3362, 27 Jun 2023
Cited by: 1 article | PMID: 37444472 | PMCID: PMC10340516
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Calibrating ensembles for scalable uncertainty quantification in deep learning-based medical image segmentation.
Buddenkotte T, Escudero Sanchez L, Crispin-Ortuzar M, Woitek R, McCague C, Brenton JD, Öktem O, Sala E, Rundo L
Comput Biol Med, 163:107096, 01 Jun 2023
Cited by: 5 articles | PMID: 37302375
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Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics.
Morse DB, Michalowski AM, Ceribelli M, De Jonghe J, Vias M, Riley D, Davies-Hill T, Voss T, Pittaluga S, Muus C, Liu J, Boyle S, Weitz DA, Brenton JD, Buenrostro JD, Knowles TPJ, Thomas CJ
Cell Syst, 14(6):464-481.e7, 01 Jun 2023
Cited by: 1 article | PMID: 37348462 | PMCID: PMC10424188
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