Europe PMC requires Javascript to function effectively.

Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page.

Search life-sciences literature (45,103,589 articles, preprints and more)

Search results

1-25 of 33 results

Sort by:

Relevance ^{Relevance: This is determined based on a ranking of criteria including term frequency, rarity of term, recency of article, whether there is a Title or Author field match, etc.}

Times cited

Date

1 2

Randomized Phase II Study of the Safety and Efficacy of Semorinemab in Participants With Mild-to-Moderate Alzheimer Disease: Lauriet.
Monteiro C, Toth B, Brunstein F, Bobbala A, Datta S, Ceniceros R, Sanabria Bohorquez SM, Anania VG, Wildsmith KR, Schauer SP, Lee J, Dolton MJ, Ramakrishnan V, Abramzon D, Teng E, Lauriet investigators
Neurology, 101(14):e1391-e1401, 29 Aug 2023
Cited by: 16 articles | PMID: 37643887 | PMCID: PMC10573141
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease: A Randomized Clinical Trial.
Teng E, Manser PT, Pickthorn K, Brunstein F, Blendstrup M, Sanabria Bohorquez S, Wildsmith KR, Toth B, Dolton M, Ramakrishnan V, Bobbala A, Sikkes SAM, Ward M, Fuji RN, Kerchner GA, Tauriel Investigators
JAMA Neurol, 79(8):758-767, 01 Aug 2022
Cited by: 49 articles | PMID: 35696185 | PMCID: PMC9194753
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS.
Katz JS, Rothstein JD, Cudkowicz ME, Genge A, Oskarsson B, Hains AB, Chen C, Galanter J, Burgess BL, Cho W, Kerchner GA, Yeh FL, Ghosh AS, Cheeti S, Brooks L, Honigberg L, Couch JA, Rothenberg ME, Brunstein F, [...] Glass JD
Ann Clin Transl Neurol, 9(1):50-66, 10 Jan 2022
Cited by: 12 articles | PMID: 35014217 | PMCID: PMC8791798
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Phase 1 Study of the Anti-HtrA1 Antibody-binding Fragment FHTR2163 in Geographic Atrophy Secondary to Age-related Macular Degeneration.
Khanani AM, Hershberger VS, Pieramici DJ, Khurana RN, Brunstein F, Ma L, Maass KF, Honigberg LA, Tom I, Chen H, Strauss EC, Lai P, Phase I Investigators
Am J Ophthalmol, 232:49-57, 29 Jun 2021
Cited by: 16 articles | PMID: 34214452
Add to export list
Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease.
Ayalon G, Lee SH, Adolfsson O, Foo-Atkins C, Atwal JK, Blendstrup M, Booler H, Bravo J, Brendza R, Brunstein F, Chan R, Chandra P, Couch JA, Datwani A, Demeule B, DiCara D, Erickson R, Ernst JA, Foreman O, [...] Kerchner GA
Sci Transl Med, 13(593):eabb2639, 01 May 2021
Cited by: 33 articles | PMID: 33980574
Add to export list
A Phase I Study of DLYE5953A, an Anti-LY6E Antibody Covalently Linked to Monomethyl Auristatin E, in Patients with Refractory Solid Tumors.
Tolaney SM, Do KT, Eder JP, LoRusso PM, Weekes CD, Chandarlapaty S, Chang CW, Chen SC, Nazzal D, Schuth E, Brunstein F, Carrasco-Triguero M, Darbonne WC, Giltnane JM, Flanagan WM, Commerford SR, Ungewickell A, Shapiro GI, Modi S
Clin Cancer Res, 26(21):5588-5597, 21 Jul 2020
Cited by: 9 articles | PMID: 32694157 | PMCID: PMC9899652
Add to export list Free full text in Europe PMC
Phase I Study of DSTP3086S, an Antibody-Drug Conjugate Targeting Six-Transmembrane Epithelial Antigen of Prostate 1, in Metastatic Castration-Resistant Prostate Cancer.
Danila DC, Szmulewitz RZ, Vaishampayan U, Higano CS, Baron AD, Gilbert HN, Brunstein F, Milojic-Blair M, Wang B, Kabbarah O, Mamounas M, Fine BM, Maslyar DJ, Ungewickell A, Scher HI
J Clin Oncol, 37(36):3518-3527, 05 Nov 2019
Cited by: 37 articles | PMID: 31689155 | PMCID: PMC7351321
Add to export list Free full text in Europe PMC
A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers.
Staton TL, Peng K, Owen R, Choy DF, Cabanski CR, Fong A, Brunstein F, Alatsis KR, Chen H
BMC Pulm Med, 19(1):5, 07 Jan 2019
Cited by: 16 articles | PMID: 30616547 | PMCID: PMC6323662
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma.
Sandhu S, McNeil CM, LoRusso P, Patel MR, Kabbarah O, Li C, Sanabria S, Flanagan WM, Yeh RF, Brunstein F, Nazzal D, Hicks R, Lemahieu V, Meng R, Hamid O, Infante JR
Invest New Drugs, 38(3):844-854, 05 Aug 2019
Cited by: 14 articles | PMID: 31385109
Add to export list
Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer's disease (BLAZE).
Salloway S, Honigberg LA, Cho W, Ward M, Friesenhahn M, Brunstein F, Quartino A, Clayton D, Mortensen D, Bittner T, Ho C, Rabe C, Schauer SP, Wildsmith KR, Fuji RN, Suliman S, Reiman EM, Chen K, Paul R
Alzheimers Res Ther, 10(1):96, 19 Sep 2018
Cited by: 60 articles | PMID: 30231896 | PMCID: PMC6146627
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
ABBY: A phase 2 randomized trial of crenezumab in mild to moderate Alzheimer disease.
Cummings JL, Cohen S, van Dyck CH, Brody M, Curtis C, Cho W, Ward M, Friesenhahn M, Rabe C, Brunstein F, Quartino A, Honigberg LA, Fuji RN, Clayton D, Mortensen D, Ho C, Paul R
Neurology, 90(21):e1889-e1897, 25 Apr 2018
Cited by: 109 articles | PMID: 29695589 | PMCID: PMC5962917
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Peripheral neuropathy with microtubule inhibitor containing antibody drug conjugates: Challenges and perspectives in translatability from nonclinical toxicology studies to the clinic.
Stagg NJ, Shen BQ, Brunstein F, Li C, Kamath AV, Zhong F, Schutten M, Fine BM
Regul Toxicol Pharmacol, 82:1-13, 20 Oct 2016
Cited by: 26 articles | PMID: 27773754
Add to export list Review
Phase I Study of DMOT4039A, an Antibody-Drug Conjugate Targeting Mesothelin, in Patients with Unresectable Pancreatic or Platinum-Resistant Ovarian Cancer.
Weekes CD, Lamberts LE, Borad MJ, Voortman J, McWilliams RR, Diamond JR, de Vries EG, Verheul HM, Lieu CH, Kim GP, Wang Y, Scales SJ, Samineni D, Brunstein F, Choi Y, Maslyar DJ, Colon-Otero G
Mol Cancer Ther, 15(3):439-447, 28 Jan 2016
Cited by: 59 articles | PMID: 26823490
Add to export list
Isolated hypoxic hepatic perfusion with melphalan in patients with irresectable ocular melanoma metastases.
van Etten B, de Wilt JH, Brunstein F, Eggermont AM, Verhoef C
Eur J Surg Oncol, 35(5):539-545, 28 Aug 2008
Cited by: 13 articles | PMID: 18760560
Add to export list
Isolated hypoxic hepatic perfusion with retrograde outflow in patients with irresectable liver metastases; a new simplified technique in isolated hepatic perfusion.
Verhoef C, de Wilt JH, Brunstein F, Marinelli AW, van Etten B, Vermaas M, Guetens G, de Boeck G, de Bruijn EA, Eggermont AM
Ann Surg Oncol, 15(5):1367-1374, 01 Feb 2008
Cited by: 12 articles | PMID: 18239976 | PMCID: PMC2277449
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Decreased response rates by the combination of histamine and IL-2 in melphalan-based isolated limb perfusion.
Brunstein F, Hoving S, aan de Wiel-Ambagtsheer G, de Bruijn EA, Guetens G, Eggermont AM, ten Hagen TL
Cancer Immunol Immunother, 56(4):573-580, 01 Aug 2006
Cited by: 7 articles | PMID: 16896966 | PMCID: PMC11030146
Add to export list Free full text in Europe PMC
Telomerase activity in prognostic histopathologic features of melanoma.
Carvalho L, Lipay M, Belfort F, Santos I, Andrade J, Haddad A, Brunstein F, Ferreira L
J Plast Reconstr Aesthet Surg, 59(9):961-968, 03 Apr 2006
Cited by: 13 articles | PMID: 16920589
Add to export list
Histamine, a vasoactive agent with vascular disrupting potential, improves tumour response by enhancing local drug delivery.
Brunstein F, Rens J, van Tiel ST, Eggermont AM, ten Hagen TL
Br J Cancer, 95(12):1663-1669, 14 Nov 2006
Cited by: 10 articles | PMID: 17106443 | PMCID: PMC2360755
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Synergistic antitumor effects of histamine plus melphalan in isolated hepatic perfusion for liver metastases.
Brunstein F, Eggermont AM, de Wiel-Ambagtsheer Ga, van Tiel ST, Rens J, ten Hagen TL
Ann Surg Oncol, 14(2):795-801, 10 Nov 2006
Cited by: 8 articles | PMID: 17096052
Add to export list
Synergistic antitumor response of interleukin 2 with melphalan in isolated limb perfusion in soft tissue sarcoma-bearing rats.
Hoving S, Brunstein F, aan de Wiel-Ambagtsheer G, van Tiel ST, de Boeck G, de Bruijn EA, Eggermont AM, ten Hagen TL
Cancer Res, 65(10):4300-4308, 01 May 2005
Cited by: 23 articles | PMID: 15899822
Add to export list
Intratumoural expression of TNF-R1 and EMAP-II in relation to response of patients treated with TNF-based isolated limb perfusion.
van Horssen R, Rens JA, Brunstein F, Guns V, van Gils M, Hagen TL, Eggermont AM
Int J Cancer, 119(6):1481-1490, 01 Sep 2006
Cited by: 8 articles | PMID: 16615114
Add to export list
Isolated hypoxic hepatic perfusion with orthograde or retrograde flow in patients with irresectable liver metastases using percutaneous balloon catheter techniques: a phase I and II study.
van Etten B, Brunstein F, van IJken MG, Marinelli AW, Verhoef C, van der Sijp JR, Guetens G, de Boeck G, de Bruijn EA, de Wilt JH, Eggermont AM
Ann Surg Oncol, 11(6):598-605, 01 Jun 2004
Cited by: 23 articles | PMID: 15172933
Add to export list
Bio-chemotherapeutic strategies and the (dis) utility of hypoxic perfusion of liver, abdomen and pelvis using balloon catheter techniques.
van Ijken MG, van Etten B, Brunstein F, ten Hagen TL, Guetens G, de Wilt JH, de Bruijn EA, Eggermont AM
Eur J Surg Oncol, 31(8):807-816, 01 Oct 2005
Cited by: 4 articles | PMID: 15951150
Add to export list Review
Isolated limb perfusion with tumor necrosis factor and melphalan prevents amputation in patients with multiple sarcomas in arm or leg.
Grünhagen DJ, Brunstein F, Graveland WJ, van Geel AN, de Wilt JH, Eggermont AM
Ann Surg Oncol, 12(6):473-479, 19 Apr 2005
Cited by: 10 articles | PMID: 15864484
Add to export list
One hundred consecutive isolated limb perfusions with TNF-alpha and melphalan in melanoma patients with multiple in-transit metastases.
Grünhagen DJ, Brunstein F, Graveland WJ, van Geel AN, de Wilt JH, Eggermont AM
Ann Surg, 240(6):939-47; discussion 947-8, 01 Dec 2004
Cited by: 73 articles | PMID: 15570199
Add to export list

1-25 of 33 results

1 2

Search life-sciences literature (45,103,589 articles, preprints and more)

Search results

Partnerships & funding