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Search life-sciences literature (45,104,145 articles, preprints and more)

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Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy.
Oliveira-Santos A, Dagda M, Wittmann J, Smalley R, Burkin DJ
Dis Model Mech, 16(6):dmm049916, 10 May 2023
Cited by: 3 articles | PMID: 37021539 | PMCID: PMC10184677
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The alpha7 integrin subunit in astrocytes promotes endothelial blood-brain barrier integrity.
Chen Z, Kelly JR, Morales JE, Sun RC, De A, Burkin DJ, McCarty JH
Development, 150(6):dev201356, 24 Mar 2023
Cited by: 2 articles | PMID: 36960827 | PMCID: PMC10112902
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A gene therapy approach for the treatment of limb-girdle muscular dystrophy 2C/R5.
Hermann H, Wuebbles RD, Burkin DJ
Mol Ther Methods Clin Dev, 29:160-161, 30 Mar 2023
Cited by: 1 article | PMID: 37063481 | PMCID: PMC10101990
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Integrin α7 Mutations Are Associated With Adult-Onset Cardiac Dysfunction in Humans and Mice.
Bugiardini E, Nunes AM, Oliveira-Santos A, Dagda M, Fontelonga TM, Barraza-Flores P, Pittman AM, Morrow JM, Parton M, Houlden H, Elliott PM, Syrris P, Maas RP, Akhtar MM, Küsters B, Raaphorst J, Schouten M, Kamsteeg EJ, van Engelen B, [...] Burkin DJ
J Am Heart Assoc, 11(23):e026494, 29 Nov 2022
Cited by: 5 articles | PMID: 36444867 | PMCID: PMC9851448
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Transgenic overexpression of α7 integrin in smooth muscle attenuates allergen-induced airway inflammation in a murine model of asthma.
Ba MA, Aiyuk A, Hernández K, Evasovic JM, Wuebbles RD, Burkin DJ, Singer CA
FASEB Bioadv, 4(11):724-740, 12 Sep 2022
Cited by: 2 articles | PMID: 36349295 | PMCID: PMC9635010
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Sunitinib inhibits STAT3 phosphorylation in cardiac muscle and prevents cardiomyopathy in the mdx mouse model of Duchenne muscular dystrophy.
Oliveira-Santos A, Dagda M, Burkin DJ
Hum Mol Genet, 31(14):2358-2369, 01 Jul 2022
Cited by: 3 articles | PMID: 35157045 | PMCID: PMC9307308
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Tetrahydrobiopterin shifts the balance from oxidative stress to NO signalling in Duchenne muscular dystrophy.
Wuebbles RD, Oliveira-Santos A, Burkin DJ
Acta Physiol (Oxf), 232(3):e13675, 26 May 2021
Cited by: 0 articles | PMID: 33998148
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Laminin-111 Improves the Anabolic Response to Mechanical Load in Aged Skeletal Muscle.
Garg K, Mahmassani ZS, Dvoretskiy S, Valero MC, Huntsman HD, Lapp S, Wu YF, Hauschka SD, Burkin DJ, Boppart MD
J Gerontol A Biol Sci Med Sci, 76(4):586-590, 01 Mar 2021
Cited by: 2 articles | PMID: 33284954 | PMCID: PMC8011696
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Laminin-111 protein therapy after disease onset slows muscle disease in a mouse model of laminin-α2 related congenital muscular dystrophy.
Barraza-Flores P, Bukovec KE, Dagda M, Conner BW, Oliveira-Santos A, Grange RW, Burkin DJ
Hum Mol Genet, 29(13):2162-2170, 01 Aug 2020
Cited by: 2 articles | PMID: 32472139 | PMCID: PMC7526790
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Laminin and Integrin in LAMA2-Related Congenital Muscular Dystrophy: From Disease to Therapeutics.
Barraza-Flores P, Bates CR, Oliveira-Santos A, Burkin DJ
Front Mol Neurosci, 13:1, 11 Feb 2020
Cited by: 16 articles | PMID: 32116540 | PMCID: PMC7026472
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Human laminin-111 and laminin-211 protein therapy prevents muscle disease progression in an immunodeficient mouse model of LAMA2-CMD.
Barraza-Flores P, Hermann HJ, Bates CR, Allen TG, Grunert TT, Burkin DJ
Skelet Muscle, 10(1):18, 04 Jun 2020
Cited by: 4 articles | PMID: 32498713 | PMCID: PMC7271547
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Human Laminin-111 and Laminin-211 protein therapy prevents muscle disease progression in an immune deficient mouse model of LAMA2-CMD
Barraza-Flores P, Hermann HJ, Bates CR, Allen TG, Grunert TT, Burkin DJ
Research Square, 20 May 2020
Cited by: 0 articles | PPR: PPR165282
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Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity.
Jones TI, Chew GL, Barraza-Flores P, Schreier S, Ramirez M, Wuebbles RD, Burkin DJ, Bradley RK, Jones PL
Skelet Muscle, 10(1):8, 11 Apr 2020
Cited by: 35 articles | PMID: 32278354 | PMCID: PMC7149937
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A retooled drug that restores ionic balance and cardiac function in dystrophin deficient hearts.
Wuebbles RD, Burkin DJ
Int J Cardiol, 319:115-116, 03 Jun 2020
Cited by: 0 articles | PMID: 32504721
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Laminin-111 protein therapy enhances muscle regeneration and repair in the GRMD dog model of Duchenne muscular dystrophy.
Barraza-Flores P, Fontelonga TM, Wuebbles RD, Hermann HJ, Nunes AM, Kornegay JN, Burkin DJ
Hum Mol Genet, 28(16):2686-2695, 01 Aug 2019
Cited by: 15 articles | PMID: 31179490 | PMCID: PMC6687953
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Human Galectin-1 Improves Sarcolemma Stability and Muscle Vascularization in the mdx Mouse Model of Duchenne Muscular Dystrophy.
Wuebbles RD, Cruz V, Van Ry P, Barraza-Flores P, Brewer PD, Jones P, Burkin DJ
Mol Ther Methods Clin Dev, 13:145-153, 22 Jan 2019
Cited by: 7 articles | PMID: 30788383 | PMCID: PMC6369265
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Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy.
Fontelonga TM, Jordan B, Nunes AM, Barraza-Flores P, Bolden N, Wuebbles RD, Griner LM, Hu X, Ferrer M, Marugan J, Southall N, Burkin DJ
Hum Mol Genet, 28(13):2120-2132, 01 Jul 2019
Cited by: 7 articles | PMID: 30806670 | PMCID: PMC6586148
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Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity
Jones TI, Chew G, Barraza-Flores P, Schreier S, Ramirez M, Wuebbles RD, Burkin DJ, Bradley RK, Jones PL
bioRxiv, 15 Nov 2018
Cited by: 0 articles | PPR: PPR62165
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Integrin α7: a major driver and therapeutic target for glioblastoma malignancy.
Nunes AM, Barraza-Flores P, Smith CR, Burkin DJ
Stem Cell Investig, 4:97, 18 Dec 2017
Cited by: 3 articles | PMID: 29359136 | PMCID: PMC5763033
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ECM-Related Myopathies and Muscular Dystrophies: Pros and Cons of Protein Therapies.
Van Ry PM, Fontelonga TM, Barraza-Flores P, Sarathy A, Nunes AM, Burkin DJ
Compr Physiol, 7(4):1519-1536, 12 Sep 2017
Cited by: 6 articles | PMID: 28915335
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Commentary: SU9516 increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy.
Sarathy A, Nunes AM, Fontelonga TM, Ogata TY, Burkin DJ
J Rare Dis Res Treat, 2(5):1-4, 29 Aug 2017
Cited by: 0 articles | PMID: 30882096 | PMCID: PMC6417831
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Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.
Nunes AM, Wuebbles RD, Sarathy A, Fontelonga TM, Deries M, Burkin DJ, Thorsteinsdóttir S
Hum Mol Genet, 26(11):2018-2033, 01 Jun 2017
Cited by: 15 articles | PMID: 28334989 | PMCID: PMC6075618
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Evaluation of the behavioral characteristics of the mdx mouse model of duchenne muscular dystrophy through operant conditioning procedures.
Lewon M, Peters CM, Van Ry PM, Burkin DJ, Hunter KW, Hayes LJ
Behav Processes, 142:8-20, 19 May 2017
Cited by: 7 articles | PMID: 28532665
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SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy.
Sarathy A, Wuebbles RD, Fontelonga TM, Tarchione AR, Mathews Griner LA, Heredia DJ, Nunes AM, Duan S, Brewer PD, Van Ry T, Hennig GW, Gould TW, Dulcey AE, Wang A, Xu X, Chen CZ, Hu X, Zheng W, Southall N, [...] Burkin DJ
Mol Ther, 25(6):1395-1407, 05 Apr 2017
Cited by: 14 articles | PMID: 28391962 | PMCID: PMC5474963
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PTRH2 gene mutation causes progressive congenital skeletal muscle pathology.
Doe J, Kaindl AM, Jijiwa M, de la Vega M, Hu H, Griffiths GS, Fontelonga TM, Barraza P, Cruz V, Van Ry P, Ramos JW, Burkin DJ, Matter ML
Hum Mol Genet, 26(8):1458-1464, 01 Apr 2017
Cited by: 8 articles | PMID: 28175314 | PMCID: PMC6075508
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