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Evidence for the evolving role of neoadjuvant and perioperative immunotherapy in resectable non-small cell lung cancer.
Hansen T, Hill J, Tincknell G, Siu D, Brungs D, Clingan P, Chantrill L, Nindra U
Explor Target Antitumor Ther, 5(6):1247-1260, 29 Sep 2024
Cited by: 0 articles | PMID: 39465010 | PMCID: PMC11502072
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Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer.
Burdett NL, Willis MO, Pandey A, Twomey L, Alaei S, Australian Ovarian Cancer Study Group, Bowtell DDL, Christie EL
Nat Commun, 15(1):6069, 18 Jul 2024
Cited by: 2 articles | PMID: 39025846 | PMCID: PMC11258338
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BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance.
Nesic K, Krais JJ, Wang Y, Vandenberg CJ, Patel P, Cai KQ, Kwan T, Lieschke E, Ho GY, Barker HE, Bedo J, Casadei S, Farrell A, Radke M, Shield-Artin K, Penington JS, Geissler F, Kyran E, Betsch R, [...] Wakefield MJ
Mol Cancer, 23(1):158, 05 Aug 2024
Cited by: 1 article | PMID: 39103848 | PMCID: PMC11299415
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Pembrolizumab with platinum-based chemotherapy with or without epacadostat as first-line treatment for metastatic non-small cell lung cancer: a randomized, partially double-blind, placebo-controlled phase II study.
Boyer M, Hui R, Urban D, Clingan P, Su WC, Devaux C, Gadgeel S, Garassino M, Leopold L, Daniel J, Munteanu MC, Samkari A, Luo Y, Abreu DR
BMC Cancer, 23(suppl 1):1250, 25 Jul 2024
Cited by: 0 articles | PMID: 39054462 | PMCID: PMC11270757
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RESILIENT Part 2: A Randomized, Open-Label Phase III Study of Liposomal Irinotecan Versus Topotecan in Adults With Relapsed Small Cell Lung Cancer.
Spigel DR, Dowlati A, Chen Y, Navarro A, Yang JC, Stojanovic G, Jove M, Rich P, Andric ZG, Wu YL, Rudin CM, Chen H, Zhang L, Yeung S, Benzaghou F, Paz-Ares L, Bunn PA, RESILIENT Trial Investigators
J Clin Oncol, 42(19):2317-2326, 22 Apr 2024
Cited by: 2 articles | PMID: 38648575 | PMCID: PMC11210946
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Small-scale mutations are infrequent as mechanisms of resistance in post-PARP inhibitor tumour samples in high grade serous ovarian cancer.
Burdett NL, Willis MO, Pandey A, Fereday S, AOCS Study Group, DeFazio A, Bowtell DDL, Christie EL
Sci Rep, 13(1):21884, 11 Dec 2023
Cited by: 2 articles | PMID: 38072854 | PMCID: PMC10711013
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The PD-1- and LAG-3-targeting bispecific molecule tebotelimab in solid tumors and hematologic cancers: a phase 1 trial.
Luke JJ, Patel MR, Blumenschein GR, Hamilton E, Chmielowski B, Ulahannan SV, Connolly RM, Santa-Maria CA, Wang J, Bahadur SW, Weickhardt A, Asch AS, Mallesara G, Clingan P, Dlugosz-Danecka M, Tomaszewska-Kiecana M, Pylypenko H, Hamad N, Kindler HL, [...] Moore PA
Nat Med, 29(11):2814-2824, 19 Oct 2023
Cited by: 23 articles | PMID: 37857711 | PMCID: PMC10667103
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Efficacy and safety of cosibelimab, an anti-PD-L1 antibody, in metastatic cutaneous squamous cell carcinoma.
Clingan P, Ladwa R, Brungs D, Harris DL, McGrath M, Arnold S, Coward J, Fourie S, Kurochkin A, Malan DR, Mant A, Sharma V, Shue H, Tazbirkova A, Berciano-Guerrero MA, Charoentum C, Dalle S, Dechaphunkul A, Dudnichenko O, [...] Desai J
J Immunother Cancer, 11(10):e007637, 01 Oct 2023
Cited by: 5 articles | PMID: 37848259 | PMCID: PMC10582968
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Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci.
DeVries AA, Dennis J, Tyrer JP, Peng PC, Coetzee SG, Reyes AL, Plummer JT, Davis BD, Chen SS, Dezem FS, Aben KKH, Anton-Culver H, Antonenkova NN, Beckmann MW, Beeghly-Fadiel A, Berchuck A, Bogdanova NV, Bogdanova-Markov N, Brenton JD, [...] Jones MR
J Natl Cancer Inst, 114(11):1533-1544, 01 Nov 2022
Cited by: 5 articles | PMID: 36210504 | PMCID: PMC9949586
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Pembrolizumab plus Chemotherapy in Advanced Triple-Negative Breast Cancer.
Cortes J, Rugo HS, Cescon DW, Im SA, Yusof MM, Gallardo C, Lipatov O, Barrios CH, Perez-Garcia J, Iwata H, Masuda N, Torregroza Otero M, Gokmen E, Loi S, Guo Z, Zhou X, Karantza V, Pan W, Schmid P, KEYNOTE-355 Investigators
N Engl J Med, 387(3):217-226, 01 Jul 2022
Cited by: 267 articles | PMID: 35857659
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Treatment With Etirinotecan Pegol for Patients With Metastatic Breast Cancer and Brain Metastases: Final Results From the Phase 3 ATTAIN Randomized Clinical Trial.
Tripathy D, Tolaney SM, Seidman AD, Anders CK, Ibrahim N, Rugo HS, Twelves C, Diéras V, Müller V, Du Y, Currie SL, Hoch U, Tagliaferri M, Hannah AL, Cortés J, ATTAIN Investigators
JAMA Oncol, 8(7):1047-1052, 01 Jul 2022
Cited by: 5 articles | PMID: 35552364 | PMCID: PMC9100460
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Immune checkpoint inhibitor-induced myocarditis, myositis, myasthenia gravis and transaminitis: a case series and review.
Wai Siu DH, O'Neill RS, Harris CA, Wang J, Ardolino L, Downton T, Tong M, Hong JH, Chin V, Clingan PR, Aghmesheh M, Soudy H
Immunotherapy, 14(7):511-520, 24 Mar 2022
Cited by: 5 articles | PMID: 35321560
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A Phase 1 Proof of Concept Study Evaluating the Addition of an LSD1 Inhibitor to Nab-Paclitaxel in Advanced or Metastatic Breast Cancer (EPI-PRIMED).
Prasanna T, Malik L, McCuaig RD, Tu WJ, Wu F, Lim PS, Tan AHY, Dahlstrom JE, Clingan P, Moylan E, Chrisp J, Fuller D, Rao S, Yip D
Front Oncol, 12:862427, 03 Jun 2022
Cited by: 2 articles | PMID: 35719960 | PMCID: PMC9205212
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Clinical and molecular profile of young adults with early-onset colorectal cancer: Experience from four Australian tertiary centers.
Siu DHW, Ali A, Tjokrowidjaja A, De Silva M, Lee J, Clingan PR, Aghmesheh M, Brungs D, Mapagu C, Goldstein D, O'Neill S, Liauw WS, Sjoquist KM, Thomas D, Pavlakis N, Clarke SJ, Diakos C, Chantrill LA
Asia Pac J Clin Oncol, 18(6):660-668, 30 Jan 2022
Cited by: 0 articles | PMID: 35098672
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Veliparib in Combination With Platinum-Based Chemotherapy for First-Line Treatment of Advanced Squamous Cell Lung Cancer: A Randomized, Multicenter Phase III Study.
Ramalingam SS, Novello S, Guclu SZ, Bentsion D, Zvirbule Z, Szilasi M, Bernabe R, Syrigos K, Byers LA, Clingan P, Bar J, Vokes EE, Govindan R, Dunbar M, Ansell P, He L, Huang X, Sehgal V, Glasgow J, [...] Mazieres J
J Clin Oncol, 39(32):3633-3644, 26 Aug 2021
Cited by: 18 articles | PMID: 34436928 | PMCID: PMC8577684
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Cemiplimab monotherapy for first-line treatment of advanced non-small-cell lung cancer with PD-L1 of at least 50%: a multicentre, open-label, global, phase 3, randomised, controlled trial.
Sezer A, Kilickap S, Gümüş M, Bondarenko I, Özgüroğlu M, Gogishvili M, Turk HM, Cicin I, Bentsion D, Gladkov O, Clingan P, Sriuranpong V, Rizvi N, Gao B, Li S, Lee S, McGuire K, Chen CI, Makharadze T, [...] Rietschel P
Lancet, 397(10274):592-604, 01 Feb 2021
Cited by: 332 articles | PMID: 33581821
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Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses.
Kang EY, Cheasley D, LePage C, Wakefield MJ, da Cunha Torres M, Rowley S, Salazar C, Xing Z, Allan P, Bowtell DDL, Mes-Masson AM, Provencher DM, Rahimi K, Kelemen LE, Fasching PA, Doherty JA, Goodman MT, Goode EL, Deen S, [...] GAMuT Collaborators
Mod Pathol, 34(1):194-206, 28 Jul 2020
Cited by: 11 articles | PMID: 32724153 | PMCID: PMC9704519
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Prognostic gene expression signature for high-grade serous ovarian cancer.
Millstein J, Budden T, Goode EL, Anglesio MS, Talhouk A, Intermaggio MP, Leong HS, Chen S, Elatre W, Gilks B, Nazeran T, Volchek M, Bentley RC, Wang C, Chiu DS, Kommoss S, Leung SCY, Senz J, Lum A, [...] Ramus SJ
Ann Oncol, 31(9):1240-1250, 28 May 2020
Cited by: 71 articles | PMID: 32473302 | PMCID: PMC7484370
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Updated Analysis From KEYNOTE-189: Pembrolizumab or Placebo Plus Pemetrexed and Platinum for Previously Untreated Metastatic Nonsquamous Non-Small-Cell Lung Cancer.
Gadgeel S, Rodríguez-Abreu D, Speranza G, Esteban E, Felip E, Dómine M, Hui R, Hochmair MJ, Clingan P, Powell SF, Cheng SY, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Garon EB, Novello S, Rubio-Viqueira B, [...] Garassino MC
J Clin Oncol, 38(14):1505-1517, 09 Mar 2020
Cited by: 497 articles | PMID: 32150489
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First-in-human phase I study of infusional and bolus schedules of Deflexifol, a novel 5-fluorouracil and leucovorin formulation, after failure of standard treatment.
Clingan PR, Ackland SP, Brungs D, de Souza P, Aghmesheh M, Garg MB, Garg MB, Ranson RD, Parker S, Jokela R, Ranson M
Asia Pac J Clin Oncol, 15(3):151-157, 06 Mar 2019
Cited by: 0 articles | PMID: 30843362
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Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma.
Kondrashova O, Topp M, Nesic K, Lieschke E, Ho GY, Harrell MI, Zapparoli GV, Hadley A, Holian R, Boehm E, Heong V, Sanij E, Pearson RB, Krais JJ, Johnson N, McNally O, Ananda S, Alsop K, Hutt KJ, [...] Scott CL
Nat Commun, 9(1):3970, 28 Sep 2018
Cited by: 144 articles | PMID: 30266954 | PMCID: PMC6162272
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Safety and Efficacy of Oxaliplatin Doublet Adjuvant Chemotherapy in Elderly Patients With Stage III Colon Cancer.
Brungs D, Aghmesheh M, de Souza P, Carolan M, Clingan P, Rose J, Ranson M
Clin Colorectal Cancer, 17(3):e549-e555, 31 May 2018
Cited by: 12 articles | PMID: 29861156
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nab-Paclitaxel plus gemcitabine in metastatic pancreatic adenocarcinoma: Australian subset analyses of the phase III MPACT trial.
Young R, Mainwaring P, Clingan P, Parnis FX, Asghari G, Beale P, Aly A, Botteman M, Romano A, Ferrara S, Margunato-Debay S, Harris M
Asia Pac J Clin Oncol, 14(5):e325-e331, 22 Jun 2018
Cited by: 2 articles | PMID: 29932294
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MyD88 and TLR4 Expression in Epithelial Ovarian Cancer.
Block MS, Vierkant RA, Rambau PF, Winham SJ, Wagner P, Traficante N, Tołoczko A, Tiezzi DG, Taran FA, Sinn P, Sieh W, Sharma R, Rothstein JH, Ramón Y Cajal T, Paz-Ares L, Oszurek O, Orsulic S, Ness RB, Nelson G, [...] Goode EL
Mayo Clin Proc, 93(3):307-320, 01 Mar 2018
Cited by: 14 articles | PMID: 29502561 | PMCID: PMC5870793
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Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.
Gandhi L, Rodríguez-Abreu D, Gadgeel S, Esteban E, Felip E, De Angelis F, Domine M, Clingan P, Hochmair MJ, Powell SF, Cheng SY, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Hui R, Garon EB, Boyer M, [...] KEYNOTE-189 Investigators
N Engl J Med, 378(22):2078-2092, 16 Apr 2018
Cited by: 3079 articles | PMID: 29658856
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