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Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice
Freytag D, Giorgiutti S, Wadier N, Depauw S, Hopsomer G, Mertz P, Augé F, Carapito R, Couillin I, Korganow A, Pala F, Bosticardo M, Notarangelo LD, Rieux-Laucat F, Riteau N, Kirstetter P, Soulas-Sprauel P
bioRxiv, 06 Nov 2024
Cited by: 0 articles | PPR: PPR936609
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Pharmacological inhibition of cathepsin S and of NSPs-AAP-1 (a novel, alternative protease driving the activation of neutrophil serine proteases).
Domain R, Seren S, Jerke U, Makridakis M, Chen KJ, Zoidakis J, Rhimi M, Zhang X, Bonvent T, Croix C, Gonzalez L, Li D, Basso J, Paget C, Viaud-Massuard MC, Lalmanach G, Shi GP, Aghdassi A, Vlahou A, [...] Korkmaz B
Biochem Pharmacol, 229:116114, 16 Sep 2024
Cited by: 0 articles | PMID: 39455238
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NLRP1 inflammasome promotes senescence and senescence-associated secretory phenotype.
Muela-Zarzuela I, Suarez-Rivero JM, Gallardo-Orihuela A, Wang C, Izawa K, de Gregorio-Procopio M, Couillin I, Ryffel B, Kitaura J, Sanz A, von Zglinicki T, Mbalaviele G, Cordero MD
Inflamm Res, 73(8):1253-1266, 21 Jun 2024
Cited by: 2 articles | PMID: 38907167 | PMCID: PMC11281979
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NLRP6 controls pulmonary inflammation from cigarette smoke in a gut microbiota-dependent manner.
Nascimento M, Huot-Marchand S, Fanny M, Straube M, Le Bert M, Savigny F, Apetoh L, Van Snick J, Trovero F, Chamaillard M, Quesniaux VFJ, Ryffel B, Gosset P, Gombault A, Riteau N, Sokol H, Couillin I
Front Immunol, 14:1224383, 11 Dec 2023
Cited by: 1 article | PMID: 38146368 | PMCID: PMC10749332
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Lung inflammation and interstitial fibrosis by targeted alveolar epithelial type I cell death.
Carignon S, De Moura Rodrigues D, Gosset D, Culerier E, Huot-Marchand S, Savigny F, Kaya E, Quesniaux V, Gombault A, Couillin I, Ryffel B, Le Bert M, Riteau N
Front Immunol, 14:1261483, 28 Sep 2023
Cited by: 1 article | PMID: 37841243 | PMCID: PMC10568624
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Pannexin 1 activity in astroglia sets hippocampal neuronal network patterns.
Vasile F, Dossi E, Moulard J, Ezan P, Lecoin L, Cohen-Salmon M, Mailly P, Le Bert M, Couillin I, Bemelmans A, Rouach N
PLoS Biol, 20(12):e3001891, 07 Dec 2022
Cited by: 6 articles | PMID: 36477165 | PMCID: PMC9728857
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STING Targeting in Lung Diseases.
de Moura Rodrigues D, Lacerda-Queiroz N, Couillin I, Riteau N
Cells, 11(21):3483, 03 Nov 2022
Cited by: 3 articles | PMID: 36359882 | PMCID: PMC9657237
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Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3.
Huot-Marchand S, Nascimento M, Culerier E, Bourenane M, Savigny F, Panek C, Serdjebi C, Le Bert M, Quesniaux VFJ, Ryffel B, Broz P, Riteau N, Gombault A, Couillin I
Front Immunol, 13:918507, 15 Aug 2022
Cited by: 10 articles | PMID: 36045672 | PMCID: PMC9421433
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STING Signaling and Sterile Inflammation.
Couillin I, Riteau N
Front Immunol, 12:753789, 01 Oct 2021
Cited by: 25 articles | PMID: 34659260 | PMCID: PMC8517477
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Gasdermins mediate cellular release of mitochondrial DNA during pyroptosis and apoptosis.
de Torre-Minguela C, Gómez AI, Couillin I, Pelegrín P
FASEB J, 35(8):e21757, 01 Aug 2021
Cited by: 48 articles | PMID: 34233045
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Chronic Pseudomonas aeruginosa Lung Infection Is IL-1R Independent, but Relies on MyD88 Signaling.
Mackowiak C, Marchiol T, Paljetak HC, Fauconnier L, Palomo J, Secher T, Panek C, Sedda D, Savigny F, Erard F, Bragonzi A, Huaux F, Stoeger T, Schiller HB, Sirard JC, Le Bert M, Couillin I, Quesniaux VFJ, Togbe D, Ryffel B
Immunohorizons, 5(5):273-283, 06 May 2021
Cited by: 1 article | PMID: 33958388
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Protective Role of the Nucleic Acid Sensor STING in Pulmonary Fibrosis.
Savigny F, Schricke C, Lacerda-Queiroz N, Meda M, Nascimento M, Huot-Marchand S, Da Gama Monteiro F, Ryffel B, Gombault A, Le Bert M, Couillin I, Riteau N
Front Immunol, 11:588799, 08 Jan 2021
Cited by: 12 articles | PMID: 33488589 | PMCID: PMC7820752
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Author Correction: Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization.
Baroja-Mazo A, Compan V, Martín-Sánchez F, Tapia-Abellán A, Couillin I, Pelegrín P
Sci Rep, 10(1):21356, 01 Dec 2020
Cited by: 0 articles | PMID: 33262522 | PMCID: PMC7708481
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B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure.
Nascimento M, Huot-Marchand S, Gombault A, Panek C, Bourinet M, Fanny M, Savigny F, Schneider P, Le Bert M, Ryffel B, Riteau N, Quesniaux VFJ, Couillin I
Front Immunol, 11:1622, 29 Jul 2020
Cited by: 10 articles | PMID: 32849550 | PMCID: PMC7405926
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Corrigendum: Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression.
Ryffel B, Huang F, Robinet P, Panek C, Couillin I, Erard F, Piotet J, Le Bert M, Mackowiak C, Torres Arias M, Dimier-Poisson I, Zheng SG
Front Immunol, 11:592865, 28 Oct 2020
Cited by: 0 articles | PMID: 33193440 | PMCID: PMC7656990
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Molecular basis of carrageenan-induced cytokines production in macrophages.
Lopes AH, Silva RL, Fonseca MD, Gomes FI, Maganin AG, Ribeiro LS, Marques LMM, Cunha FQ, Alves-Filho JC, Zamboni DS, Lopes NP, Franklin BS, Gombault A, Ramalho FS, Quesniaux VFJ, Couillin I, Ryffel B, Cunha TM
Cell Commun Signal, 18(1):141, 07 Sep 2020
Cited by: 11 articles | PMID: 32894139 | PMCID: PMC7487827
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P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment.
Brisson L, Chadet S, Lopez-Charcas O, Jelassi B, Ternant D, Chamouton J, Lerondel S, Le Pape A, Couillin I, Gombault A, Trovero F, Chevalier S, Besson P, Jiang LH, Roger S
Cancers (Basel), 12(9):E2342, 19 Aug 2020
Cited by: 17 articles | PMID: 32825056 | PMCID: PMC7565976
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IL-17 suppresses the therapeutic activity of cancer vaccines through the inhibition of CD8⁺ T-cell responses.
Dadaglio G, Fayolle C, Oberkampf M, Tang A, Rudilla F, Couillin I, Torheim EA, Rosenbaum P, Leclerc C
Oncoimmunology, 9(1):1758606, 12 May 2020
Cited by: 8 articles | PMID: 32923117 | PMCID: PMC7458594
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Self-DNA release and STING-dependent sensing drives inflammation to cigarette smoke in mice.
Nascimento M, Gombault A, Lacerda-Queiroz N, Panek C, Savigny F, Sbeity M, Bourinet M, Le Bert M, Riteau N, Ryffel B, Quesniaux VFJ, Couillin I
Sci Rep, 9(1):14848, 16 Oct 2019
Cited by: 33 articles | PMID: 31619733 | PMCID: PMC6795997
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Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression.
Ryffel B, Huang F, Robinet P, Panek C, Couillin I, Erard F, Piotet J, Le Bert M, Mackowiak C, Torres Arias M, Dimier-Poisson I, Zheng SG
Front Immunol, 10:702, 18 Apr 2019
Cited by: 9 articles | PMID: 31057534 | PMCID: PMC6482336
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Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization.
Baroja-Mazo A, Compan V, Martín-Sánchez F, Tapia-Abellán A, Couillin I, Pelegrín P
Sci Rep, 9(1):5788, 08 Apr 2019
Cited by: 16 articles | PMID: 30962463 | PMCID: PMC6453936
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The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin.
Fanny M, Nascimento M, Baron L, Schricke C, Maillet I, Akbal M, Riteau N, Le Bert M, Quesniaux V, Ryffel B, Gombault A, Même S, Même W, Couillin I
Front Immunol, 9:1476, 25 Jun 2018
Cited by: 19 articles | PMID: 29988569 | PMCID: PMC6026799
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Inflammation drives nitric oxide synthase 2 expression by γδ T cells and affects the balance between melanoma and vitiligo associated melanoma.
Douguet L, Bod L, Bod L, Labarthe L, Lengagne R, Kato M, Couillin I, Prévost-Blondel A
Oncoimmunology, 7(9):e1484979, 30 Jul 2018
Cited by: 9 articles | PMID: 30228955 | PMCID: PMC6140581
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Pannexin-1 channels contribute to seizure generation in human epileptic brain tissue and in a mouse model of epilepsy.
Dossi E, Blauwblomme T, Moulard J, Chever O, Vasile F, Guinard E, Le Bert M, Couillin I, Pallud J, Capelle L, Huberfeld G, Rouach N
Sci Transl Med, 10(443):eaar3796, 01 May 2018
Cited by: 54 articles | PMID: 29848662
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Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension.
Parpaleix A, Amsellem V, Houssaini A, Abid S, Breau M, Marcos E, Sawaki D, Delcroix M, Quarck R, Maillard A, Couillin I, Ryffel B, Adnot S
Eur Respir J, 48(2):470-483, 13 Jul 2016
Cited by: 57 articles | PMID: 27418552
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1-25 of 75 results

1 2 3

Search life-sciences literature (45,100,050 articles, preprints and more)

Search results

Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice

Pharmacological inhibition of cathepsin S and of NSPs-AAP-1 (a novel, alternative protease driving the activation of neutrophil serine proteases).

NLRP1 inflammasome promotes senescence and senescence-associated secretory phenotype.

NLRP6 controls pulmonary inflammation from cigarette smoke in a gut microbiota-dependent manner.

Lung inflammation and interstitial fibrosis by targeted alveolar epithelial type I cell death.

Pannexin 1 activity in astroglia sets hippocampal neuronal network patterns.

STING Targeting in Lung Diseases.

Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3.

STING Signaling and Sterile Inflammation.

Gasdermins mediate cellular release of mitochondrial DNA during pyroptosis and apoptosis.

Chronic Pseudomonas aeruginosa Lung Infection Is IL-1R Independent, but Relies on MyD88 Signaling.

Protective Role of the Nucleic Acid Sensor STING in Pulmonary Fibrosis.

Author Correction: Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization.

B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure.

Corrigendum: Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression.

Molecular basis of carrageenan-induced cytokines production in macrophages.

P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment.

IL-17 suppresses the therapeutic activity of cancer vaccines through the inhibition of CD8⁺ T-cell responses.

Self-DNA release and STING-dependent sensing drives inflammation to cigarette smoke in mice.

Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression.

Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization.

The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin.

Inflammation drives nitric oxide synthase 2 expression by γδ T cells and affects the balance between melanoma and vitiligo associated melanoma.

Pannexin-1 channels contribute to seizure generation in human epileptic brain tissue and in a mouse model of epilepsy.

Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension.

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