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Search life-sciences literature (45,103,589 articles, preprints and more)

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1-25 of 31 results

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Correction: Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates.
Burdo TH, Chen C, Kaminski R, Sariyer IK, Mancuso P, Donadoni M, Smith MD, Sariyer R, Caocci M, Liao S, Liu H, Huo W, Zhao H, Misamore J, Lewis MG, Simonyan V, Thompson EE, Xu EY, Cradick TJ, [...] Khalili K
Gene Ther, 31(7-8):434-435, 01 Jul 2024
Cited by: 0 articles | PMID: 38212405 | PMCID: PMC11257951
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Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates.
Burdo TH, Chen C, Kaminski R, Sariyer IK, Mancuso P, Donadoni M, Smith MD, Sariyer R, Caocci M, Liao S, Liu H, Huo W, Zhao H, Misamore J, Lewis MG, Simonyan V, Thompson EE, Thompson EE, Xu EY, [...] Khalili K
Gene Ther, 31(5-6):224-233, 17 Aug 2023
Cited by: 7 articles | PMID: 37587230 | PMCID: PMC11090835
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Strategic self-limiting production of infectious HIV particles by CRISPR in permissive cells.
Liu H, Chen C, Liao S, Sohaii DK, Cruz CRY, Burdo TH, Cradick TJ, Mehta A, Barrero C, Florez M, Gordon J, Grauzam S, Dressman J, Amini S, Bollard CM, Kaminski R, Khalili K
Mol Ther Nucleic Acids, 32:1010-1025, 19 May 2023
Cited by: 3 articles | PMID: 37346975 | PMCID: PMC10280355
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In vivo genome editing at the albumin locus to treat methylmalonic acidemia.
Schneller JL, Lee CM, Venturoni LE, Chandler RJ, Li A, Myung S, Cradick TJ, Hurley AE, Lagor WR, Bao G, Venditti CP
Mol Ther Methods Clin Dev, 23:619-632, 11 Nov 2021
Cited by: 8 articles | PMID: 34901307 | PMCID: PMC8634044
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Base Editors Flex Sights on Sickle-Cell Disease.
Cereseto A, Cradick TJ, Davies K
CRISPR J, 4(2):166-168, 01 Apr 2021
Cited by: 0 articles | PMID: 33876950
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Evaluation of Homology-Independent CRISPR-Cas9 Off-Target Assessment Methods.
Chaudhari HG, Penterman J, Whitton HJ, Spencer SJ, Flanagan N, Lei Zhang MC, Huang E, Khedkar AS, Toomey JM, Shearer CA, Needham AW, Ho TW, Kulman JD, Cradick TJ, Kernytsky A
CRISPR J, 3(6):440-453, 01 Dec 2020
Cited by: 19 articles | PMID: 33346710 | PMCID: PMC7757695
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Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus.
Antoniani C, Meneghini V, Lattanzi A, Felix T, Romano O, Magrin E, Weber L, Pavani G, El Hoss S, Kurita R, Nakamura Y, Cradick TJ, Lundberg AS, Porteus M, Amendola M, El Nemer W, Cavazzana M, Mavilio F, Miccio A
Blood, 131(17):1960-1973, 08 Mar 2018
Cited by: 102 articles | PMID: 29519807
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Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome.
Müller M, Lee CM, Gasiunas G, Davis TH, Cradick TJ, Siksnys V, Bao G, Cathomen T, Mussolino C
Mol Ther, 24(3):636-644, 14 Dec 2015
Cited by: 129 articles | PMID: 26658966 | PMCID: PMC4786917
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A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood.
Zhao J, Akinsanmi I, Arafat D, Cradick TJ, Lee CM, Banskota S, Marigorta UM, Bao G, Gibson G
Am J Hum Genet, 98(2):299-309, 01 Feb 2016
Cited by: 50 articles | PMID: 26849112 | PMCID: PMC4746369
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The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells.
Lee CM, Cradick TJ, Bao G
Mol Ther, 24(3):645-654, 19 Jan 2016
Cited by: 120 articles | PMID: 26782639 | PMCID: PMC4786937
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Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing.
Lee CM, Cradick TJ, Fine EJ, Bao G
Mol Ther, 24(3):475-487, 11 Jan 2016
Cited by: 54 articles | PMID: 26750397 | PMCID: PMC4786925
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TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs.
Suzuki S, Sargent RG, Illek B, Fischer H, Esmaeili-Shandiz A, Yezzi MJ, Lee A, Yang Y, Kim S, Renz P, Qi Z, Yu J, Muench MO, Beyer AI, Guimarães AO, Ye L, Chang J, Fine EJ, Cradick TJ, [...] Gruenert DC
Mol Ther Nucleic Acids, 5:e273, 05 Jan 2016
Cited by: 29 articles | PMID: 26730810 | PMCID: PMC5012545
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An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage.
Fine EJ, Cradick TJ, Zhao CL, Lin Y, Bao G
Nucleic Acids Res, 42(6):e42, 30 Dec 2013
Cited by: 78 articles | PMID: 24381193 | PMCID: PMC3973315
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SAPTA: a new design tool for improving TALE nuclease activity.
Lin Y, Fine EJ, Zheng Z, Antico CJ, Voit RA, Porteus MH, Cradick TJ, Bao G
Nucleic Acids Res, 42(6):e47, 16 Jan 2014
Cited by: 31 articles | PMID: 24442582 | PMCID: PMC3973288
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CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences.
Lin Y, Cradick TJ, Brown MT, Deshmukh H, Ranjan P, Sarode N, Wile BM, Vertino PM, Stewart FJ, Bao G
Nucleic Acids Res, 42(11):7473-7485, 16 May 2014
Cited by: 353 articles | PMID: 24838573 | PMCID: PMC4066799
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High-throughput cellular screening of engineered nuclease activity using the single-strand annealing assay and luciferase reporter.
Cradick TJ, Antico CJ, Bao G
Methods Mol Biol, 1114:339-352, 01 Jan 2014
Cited by: 7 articles | PMID: 24557914
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Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models.
Fine EJ, Cradick TJ, Bao G
Methods Mol Biol, 1114:371-383, 01 Jan 2014
Cited by: 2 articles | PMID: 24557916
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COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites.
Cradick TJ, Qiu P, Lee CM, Fine EJ, Bao G
Mol Ther Nucleic Acids, 3:e214, 02 Dec 2014
Cited by: 222 articles | PMID: 25462530 | PMCID: PMC4272406
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Codon swapping of zinc finger nucleases confers expression in primary cells and in vivo from a single lentiviral vector.
Abarrategui-Pontes C, Créneguy A, Thinard R, Fine EJ, Thepenier V, Fournier le RL, Cradick TJ, Bao G, Tesson L, Podevin G, Anegon I, Nguyen TH
Curr Gene Ther, 14(5):365-376, 01 Jan 2014
Cited by: 4 articles | PMID: 25687502
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Nanomedicine: tiny particles and machines give huge gains.
Tong S, Fine EJ, Lin Y, Cradick TJ, Bao G
Ann Biomed Eng, 42(2):243-259, 03 Dec 2013
Cited by: 12 articles | PMID: 24297494 | PMCID: PMC3962788
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Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection.
Ye L, Wang J, Beyer AI, Teque F, Cradick TJ, Qi Z, Chang JC, Bao G, Muench MO, Yu J, Levy JA, Kan YW
Proc Natl Acad Sci U S A, 111(26):9591-9596, 09 Jun 2014
Cited by: 187 articles | PMID: 24927590 | PMCID: PMC4084478
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TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity.
Mussolino C, Alzubi J, Fine EJ, Morbitzer R, Cradick TJ, Lahaye T, Bao G, Cathomen T
Nucleic Acids Res, 42(10):6762-6773, 03 May 2014
Cited by: 102 articles | PMID: 24792154 | PMCID: PMC4041469
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DNA targeting specificity of RNA-guided Cas9 nucleases.
Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F
Nat Biotechnol, 31(9):827-832, 21 Jul 2013
Cited by: 2645 articles | PMID: 23873081 | PMCID: PMC3969858
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Designing and testing the activities of TAL effector nucleases.
Lin Y, Cradick TJ, Bao G
Methods Mol Biol, 1114:203-219, 01 Jan 2014
Cited by: 6 articles | PMID: 24557905
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Engineering imaging probes and molecular machines for nanomedicine.
Tong S, Cradick TJ, Ma Y, Dai Z, Bao G
Sci China Life Sci, 55(10):843-861, 31 Oct 2012
Cited by: 3 articles | PMID: 23108862
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1-25 of 31 results

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Search life-sciences literature (45,103,589 articles, preprints and more)

Search results

Correction: Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates.

Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates.

Strategic self-limiting production of infectious HIV particles by CRISPR in permissive cells.

In vivo genome editing at the albumin locus to treat methylmalonic acidemia.

Base Editors Flex Sights on Sickle-Cell Disease.

Evaluation of Homology-Independent CRISPR-Cas9 Off-Target Assessment Methods.

Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus.

Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome.

A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood.

The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells.

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing.

TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs.

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage.

SAPTA: a new design tool for improving TALE nuclease activity.

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences.

High-throughput cellular screening of engineered nuclease activity using the single-strand annealing assay and luciferase reporter.

Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models.

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites.

Codon swapping of zinc finger nucleases confers expression in primary cells and in vivo from a single lentiviral vector.

Nanomedicine: tiny particles and machines give huge gains.

Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection.

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity.

DNA targeting specificity of RNA-guided Cas9 nucleases.

Designing and testing the activities of TAL effector nucleases.

Engineering imaging probes and molecular machines for nanomedicine.

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