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Search life-sciences literature (45,105,671 articles, preprints and more)

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Pharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes.
Truesdell P, Chang J, Coto Villa D, Dai M, Zhao Y, McIlwain R, Young S, Hiley S, Craig AW, Babak T
NPJ Precis Oncol, 8(1):186, 28 Aug 2024
Cited by: 0 articles | PMID: 39198692 | PMCID: PMC11358483
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Blockade of TGF-β and PD-L1 by bintrafusp alfa promotes survival in preclinical ovarian cancer models by promoting T effector and NK cell responses.
Kment J, Newsted D, Young S, Vermeulen MC, Laight BJ, Greer PA, Lan Y, Craig AW
Br J Cancer, 130(12):2003-2015, 15 Apr 2024
Cited by: 1 article | PMID: 38622286 | PMCID: PMC11183086
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Fes-deficient macrophages enhance CD8⁺T cell priming and tumour control through increased pro-inflammatory cytokine production and localization
Laight BJ, Harper D, Dmytryk N, Zhang S, Garven A, Shi C, Nauman R, Kment J, Alotaibi F, Shapavalov I, Gao Y, Mewburn J, Vlasschaert C, LeBrun D, Tyryshkin K, Berman D, Simpson A, Graham C, Craig AW, [...] Greer PA
bioRxiv, 02 Mar 2024
Cited by: 0 articles | PPR: PPR813560
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Toward a Template for Synthetic Actin-Targeting Macrolide Analogues That Inhibit Cancer Cell Invasiveness.
Trofimova DN, Aeluri M, Veeranna KD, Jiang Y, Grange RL, Pipaliya BV, Subaramanian M, Craig AW, Evans PA, Allingham JS
J Med Chem, 67(7):5315-5332, 24 Feb 2024
Cited by: 0 articles | PMID: 38401158
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Advancing cancer immunotherapy: from innovative preclinical models to clinical insights.
Craig AW, Frieboes HB, Videira PA
Sci Rep, 14(1):1205, 12 Jan 2024
Cited by: 0 articles | PMID: 38216668 | PMCID: PMC10786836
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Pharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes
Truesdell P, Chang J, Villa DC, Dai M, Zhao Y, McIlwain R, Young S, Hiley S, Craig AW, Babak T
bioRxiv, 07 Jan 2024
Cited by: 0 articles | PPR: PPR783506
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Synergistic effects of inhibitors targeting PI3K and Aurora Kinase A in preclinical inflammatory breast cancer models
Al Ali N, Kment J, Young S, Craig AW
bioRxiv, 13 Aug 2023
Cited by: 0 articles | PPR: PPR706454
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Autophagy mediates cancer cell resistance to doxorubicin induced by the Programmed Death 1/Programmed Death Ligand 1 immune checkpoint axis
Minassian L, Sanwalka D, Paré J, Macdonald-Goodfellow S, Sutherland RL, Ghaffari A, Margerum CL, Koti M, Craig AW, Cotechini T, Siemens DR, Chan E, Graham CH
bioRxiv, 18 Jan 2023
Cited by: 0 articles | PPR: PPR598425
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Estrogen mediates inflammatory role of mast cells in endometriosis pathophysiology.
McCallion A, Nasirzadeh Y, Lingegowda H, Miller JE, Khalaj K, Ahn S, Monsanto SP, Bidarimath M, Sisnett DJ, Craig AW, Young SL, Lessey BA, Koti M, Tayade C
Front Immunol, 13:961599, 09 Aug 2022
Cited by: 14 articles | PMID: 36016927 | PMCID: PMC9396281
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Wild-type p53 suppresses formin-binding protein-17 (FBP17) to reduce invasion.
Suman P, Mehta V, Craig AWB, Chander H
Carcinogenesis, 43(5):494-503, 01 Jun 2022
Cited by: 3 articles | PMID: 35134126
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Truncated Actin-Targeting Macrolide Derivative Blocks Cancer Cell Motility and Invasion of Extracellular Matrix.
Pipaliya BV, Trofimova DN, Grange RL, Aeluri M, Deng X, Shah K, Craig AW, Allingham JS, Evans PA
J Am Chem Soc, 143(18):6847-6854, 03 May 2021
Cited by: 7 articles | PMID: 33938740
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Impact of Endocytosis Mechanisms for the Receptors Targeted by the Currently Approved Antibody-Drug Conjugates (ADCs)-A Necessity for Future ADC Research and Development.
Hammood M, Craig AW, Leyton JV
Pharmaceuticals (Basel), 14(7):674, 15 Jul 2021
Cited by: 23 articles | PMID: 34358100 | PMCID: PMC8308841
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Distinguishing Tumor and Stromal Sources of MicroRNAs Linked to Metastasis in Cutaneous Melanoma.
Watt K, Tyryshkin K, Renwick N, Craig AWB
Transl Oncol, 13(9):100802, 28 May 2020
Cited by: 4 articles | PMID: 32474365 | PMCID: PMC7260684
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A packaged mindset: How elongated packages induce healthy mindsets.
Sheehan D, Van Ittersum K, Craig AW, Romero M
Appetite, 150:104657, 10 Mar 2020
Cited by: 0 articles | PMID: 32169595
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Mast cells enhance sterile inflammation in chronic nonbacterial osteomyelitis.
Young S, Sharma N, Lee JH, Chitu V, Neumeister V, Sohr E, Stanley ER, Hedrich CM, Craig AWB
Dis Model Mech, 12(8):dmm040097, 20 Aug 2019
Cited by: 9 articles | PMID: 31416928 | PMCID: PMC6737947
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A PKA/cdc42 Signaling Axis Restricts Angiogenic Sprouting by Regulating Podosome Rosette Biogenesis and Matrix Remodeling.
MacKeil JL, Brzezinska P, Burke-Kleinman J, Craig AW, Nicol CJB, Maurice DH
Sci Rep, 9(1):2385, 20 Feb 2019
Cited by: 6 articles | PMID: 30787359 | PMCID: PMC6382826
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Blockade of TGF-β signaling with novel synthetic antibodies limits immune exclusion and improves chemotherapy response in metastatic ovarian cancer models.
Newsted D, Banerjee S, Watt K, Nersesian S, Truesdell P, Blazer LL, Cardarelli L, Adams JJ, Sidhu SS, Craig AW
Oncoimmunology, 8(2):e1539613, 20 Nov 2018
Cited by: 31 articles | PMID: 30713798 | PMCID: PMC6343786
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Neural correlates of intertemporal choice in aggressive behavior.
Chester DS, Bell SB, DeWall CN, West SJ, Romero-Lopez M, Craig AW
Aggress Behav, 45(5):507-516, 15 Apr 2019
Cited by: 6 articles | PMID: 30989667 | PMCID: PMC7388593
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Effects of Modulating Actin Dynamics on HER2 Cancer Cell Motility and Metastasis.
Nersesian S, Williams R, Newsted D, Shah K, Young S, Evans PA, Allingham JS, Craig AW
Sci Rep, 8(1):17243, 22 Nov 2018
Cited by: 7 articles | PMID: 30467396 | PMCID: PMC6250728
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Mast Cells Enhance Sterile Inflammation in Chronic Nonbacterial Osteomyelitis
Young S, Sharma N, Lee JHP, Chitu V, Neumeister V, Sohr E, Stanley ER, Hedrich CM, Craig AW
bioRxiv, 16 Feb 2018
Cited by: 0 articles | PPR: PPR18650
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MicroRNA-206 suppresses TGF-β signalling to limit tumor growth and metastasis in lung adenocarcinoma.
Watt K, Newsted D, Voorand E, Gooding RJ, Majewski A, Truesdell P, Yao B, Tuschl T, Renwick N, Craig AW
Cell Signal, 50:25-36, 20 Jun 2018
Cited by: 17 articles | PMID: 29935234
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Endophilin A2 promotes HER2 internalization and sensitivity to trastuzumab-based therapy in HER2-positive breast cancers.
Baldassarre T, Truesdell P, Craig AW
Breast Cancer Res, 19(1):110, 03 Oct 2017
Cited by: 19 articles | PMID: 28974266 | PMCID: PMC5627411
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A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.
Ling B, Watt K, Banerjee S, Newsted D, Truesdell P, Adams J, Sidhu SS, Craig AWB
Oncotarget, 8(35):58372-58385, 09 May 2017
Cited by: 49 articles | PMID: 28938563 | PMCID: PMC5601659
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CXCL10 alters the tumour immune microenvironment and disease progression in a syngeneic murine model of high-grade serous ovarian cancer.
K Au K, Peterson N, Truesdell P, Reid-Schachter G, Khalaj K, Ren R, Francis JA, Graham CH, Craig AW, Koti M
Gynecol Oncol, 145(3):436-445, 17 Mar 2017
Cited by: 29 articles | PMID: 28318643
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STAT1-associated intratumoural T_H1 immunity predicts chemotherapy resistance in high-grade serous ovarian cancer.
Au KK, Le Page C, Ren R, Meunier L, Clément I, Tyrishkin K, Peterson N, Kendall-Dupont J, Childs T, Francis JA, Graham CH, Craig AW, Squire JA, Mes-Masson AM, Koti M
J Pathol Clin Res, 2(4):259-270, 19 Sep 2016
Cited by: 36 articles | PMID: 27917296 | PMCID: PMC5129574
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