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Search life-sciences literature (45,100,050 articles, preprints and more)

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Leukemia inhibitory factor receptor inhibition by EC359 reduces atherosclerotic stenosis grade in Ldlr<sup>-/-</sup> mice.
Hemme E, Depuydt MAC, van Santbrink PJ, Wezel A, Smeets HJ, Foks AC, Kuiper J, Bot I
Eur J Pharmacol, 985:177121, 09 Nov 2024
Cited by: 0 articles | PMID: 39528103
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Sexual dimorphism in atherosclerotic plaques of aged Ldlr^-/- mice.
Smit V, de Mol J, Kleijn MNAB, Depuydt MAC, de Winther MPJ, Bot I, Kuiper J, Foks AC
Immun Ageing, 21(1):27, 02 May 2024
Cited by: 0 articles | PMID: 38698438 | PMCID: PMC11064395
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Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice.
Schaftenaar FH, van Dam AD, de Bruin G, Depuydt MAC, de Mol J, Amersfoort J, Douna H, Meijer M, Kröner MJ, van Santbrink PJ, Bernabé Kleijn MNA, van Puijvelde GHM, Florea BI, Slütter B, Foks AC, Bot I, Rensen PCN, Kuiper J
Arterioscler Thromb Vasc Biol, 44(6):1346-1364, 25 Apr 2024
Cited by: 0 articles | PMID: 38660806 | PMCID: PMC11188635
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Virus-Associated CD8<sup>+</sup> T-Cells Are Not Activated Through Antigen-Mediated Interaction Inside Atherosclerotic Lesions.
de Jong MJM, Schaftenaar FH, Depuydt MAC, Lozano Vigario F, Janssen GMC, Peeters JAHM, Goncalves L, Wezel A, Smeets HJ, Kuiper J, Bot I, van Veelen P, Slütter B
Arterioscler Thromb Vasc Biol, 44(6):1302-1314, 21 Mar 2024
Cited by: 0 articles | PMID: 38511327
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Resident Memory T Cells in the Atherosclerotic Lesion Associate With Reduced Macrophage Content and Increased Lesion Stability.
de Jong MJM, Depuydt MAC, Schaftenaar FH, Liu K, Maters D, Wezel A, Smeets HJ, Kuiper J, Bot I, van Gisbergen K, Slütter B
Arterioscler Thromb Vasc Biol, 44(6):1318-1329, 18 Apr 2024
Cited by: 0 articles | PMID: 38634281
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Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation.
Mulholland M, Depuydt MAC, Jakobsson G, Ljungcrantz I, Grentzmann A, To F, Bengtsson E, Jaensson Gyllenbäck E, Grönberg C, Rattik S, Liberg D, Schiopu A, Björkbacka H, Kuiper J, Bot I, Slütter B, Engelbertsen D
Cardiovasc Res, 120(6):581-595, 01 May 2024
Cited by: 1 article | PMID: 38563353 | PMCID: PMC11074796
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Single-cell profiling reveals age-associated immunity in atherosclerosis.
Smit V, de Mol J, Schaftenaar FH, Depuydt MAC, Postel RJ, Smeets D, Verheijen FWM, Bogers L, van Duijn J, Verwilligen RAF, Grievink HW, Bernabé Kleijn MNA, van Ingen E, de Jong MJM, Goncalves L, Peeters JAHM, Smeets HJ, Wezel A, Polansky JK, [...] Foks AC
Cardiovasc Res, 119(15):2508-2521, 01 Nov 2023
Cited by: 13 articles | PMID: 37390467 | PMCID: PMC10676459
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Female Gene Networks Are Expressed in Myofibroblast-Like Smooth Muscle Cells in Vulnerable Atherosclerotic Plaques.
Diez Benavente E, Karnewar S, Buono M, Mili E, Hartman RJG, Kapteijn D, Slenders L, Daniels M, Aherrahrou R, Reinberger T, Mol BM, de Borst GJ, de Kleijn DPV, Prange KHM, Depuydt MAC, de Winther MPJ, Kuiper J, Björkegren JLM, Erdmann J, [...] den Ruijter HM
Arterioscler Thromb Vasc Biol, 43(10):1836-1850, 17 Aug 2023
Cited by: 3 articles | PMID: 37589136 | PMCID: PMC10521798
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Identification of endothelial-to-mesenchymal transition gene signatures in single-cell transcriptomics of human atherosclerotic tissue
Slenders L, Wesseling M, Boltjes A, Kapteijn DM, Depuydt MA, Prange K, van den Dungen NA, Benavente ED, P.V. de Kleijn D, de Borst GJ, den Ruijter HM, Owens GK, Mokry M, Pasterkamp G
bioRxiv, 18 Jul 2023
Cited by: 0 articles | PPR: PPR694048
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Bruton's Tyrosine Kinase inhibition by Acalabrutinib does not affect early or advanced atherosclerotic plaque size and morphology in Ldlr^-/- mice.
Hemme E, Biskop D, Depuydt MAC, Smit V, Delfos L, Bernabé Kleijn MNA, Foks AC, Kuiper J, Bot I
Vascul Pharmacol, 150:107172, 17 Apr 2023
Cited by: 2 articles | PMID: 37075932
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Time-restricted feeding attenuates hypercholesterolaemia and atherosclerosis development during circadian disturbance in APOE∗3-Leiden.CETP mice.
In Het Panhuis W, Schönke M, Modder M, Tom HE, Lalai RA, Pronk ACM, Streefland TCM, van Kerkhof LWM, Dollé MET, Depuydt MAC, Bot I, Vos WG, Bosmans LA, van Os BW, Lutgens E, Rensen PCN, Kooijman S
EBioMedicine, 93:104680, 23 Jun 2023
Cited by: 10 articles | PMID: 37356205 | PMCID: PMC10320519
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Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation.
Mokry M, Boltjes A, Slenders L, Bel-Bordes G, Cui K, Brouwer E, Mekke JM, Depuydt MAC, Timmerman N, Waissi F, Verwer MC, Turner AW, Khan MD, Hodonsky CJ, Benavente ED, Hartman RJG, van den Dungen NAM, Lansu N, Nagyova E, [...] Pasterkamp G
Nat Cardiovasc Res, 1(12):1140-1155, 12 Dec 2022
Cited by: 10 articles | PMID: 37920851 | PMCID: PMC10621615
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Blockade of the BLT1-LTB₄ axis does not affect mast cell migration towards advanced atherosclerotic lesions in LDLr^-/- mice.
Depuydt MAC, Vlaswinkel FD, Hemme E, Delfos L, Kleijn MNAB, van Santbrink PJ, Foks AC, Slütter B, Kuiper J, Bot I
Sci Rep, 12(1):18362, 01 Nov 2022
Cited by: 2 articles | PMID: 36319730 | PMCID: PMC9626554
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Female gene networks are expressed in myofibroblast-like smooth muscle cells in vulnerable atherosclerotic plaques
Benavente ED, Karnewar S, Buono M, Mili E, Hartman RJG, Kapteijn D, Slenders L, Daniels M, Aherrahrou R, Reinberger T, Mol BM, de Borst GJ, de Kleijn DPV, Prange KHM, Depuydt MAC, de Winther MPJ, Kuiper J, Björkegren JLM, Erdmann J, [...] den Ruijter HM
bioRxiv, 11 Feb 2023
Cited by: 0 articles | PPR: PPR615511
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Single-cell T cell receptor sequencing of paired human atherosclerotic plaques and blood reveals autoimmune-like features of expanded effector T cells.
Depuydt MAC, Schaftenaar FH, Prange KHM, Boltjes A, Hemme E, Delfos L, de Mol J, de Jong MJM, Bernabé Kleijn MNA, Peeters JAHM, Goncalves L, Wezel A, Smeets HJ, de Borst GJ, Foks AC, Pasterkamp G, de Winther MPJ, Kuiper J, Bot I, Slütter B
Nat Cardiovasc Res, 2(2):112-125, 30 Jan 2023
Cited by: 24 articles | PMID: 38665903 | PMCID: PMC11041750
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Transcriptomic-based clustering of advanced atherosclerotic plaques identifies subgroups of plaques with differential underlying biology that associate with clinical presentation
Mokry M, Boltjes A, Cui K, Slenders L, Mekke JM, Depuydt MA, Timmerman N, Waissi F, Verwer MC, Turner AW, Khan MD, Hodonsky CJ, Benavente ED, Hartman RJ, van den Dungen NAM, Lansu N, Nagyova E, Prange KH, Pavlos E, [...] Pasterkamp G
medRxiv, 26 Nov 2021
Cited by: 0 articles | PPR: PPR425575
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Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis.
Slenders L, Landsmeer LPL, Cui K, Depuydt MAC, Verwer M, Mekke J, Timmerman N, van den Dungen NAM, Kuiper J, de Winther MPJ, Prange KHM, Ma WF, Miller CL, Aherrahrou R, Civelek M, de Borst GJ, de Kleijn DPV, Asselbergs FW, den Ruijter HM, [...] Mokry M
Eur Heart J Open, 2(1):oeab043, 21 Dec 2021
Cited by: 24 articles | PMID: 35174364 | PMCID: PMC8841481
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Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis
Slenders L, Landsmeer LPL, Cui K, Depuydt MA, Verwer M, Mekke J, Timmerman N, van den Dungen NA, Kuiper J, Winther MP, Prange KH, Ma WF, Miller CL, Aherrahrou R, Civelek M, de Borst GJ, de Kleijn DP, Asselbergs FW, den Ruijter HM, [...] Mokry M
medRxiv, 24 Nov 2021
Cited by: 0 articles | PPR: PPR423868
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Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics.
Depuydt MAC, Prange KHM, Slenders L, Örd T, Elbersen D, Boltjes A, de Jager SCA, Asselbergs FW, de Borst GJ, Aavik E, Lönnberg T, Lutgens E, Glass CK, den Ruijter HM, Kaikkonen MU, Bot I, Slütter B, van der Laan SW, Yla-Herttuala S, [...] Pasterkamp G
Circ Res, 127(11):1437-1455, 28 Sep 2020
Cited by: 231 articles | PMID: 32981416 | PMCID: PMC7641189
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VLDL/LDL serves as the primary source of cholesterol in the adrenal glucocorticoid response to food deprivation.
van der Sluis RJ, Depuydt MAC, Van Eck M, Hoekstra M
Biochim Biophys Acta Mol Cell Biol Lipids, 1865(7):158682, 10 Mar 2020
Cited by: 2 articles | PMID: 32169652
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B- and T-lymphocyte attenuator stimulation protects against atherosclerosis by regulating follicular B cells.
Douna H, Amersfoort J, Schaftenaar FH, Kröner MJ, Kiss MG, Slütter B, Depuydt MAC, Bernabé Kleijn MNA, Wezel A, Smeets HJ, Yagita H, Binder CJ, Bot I, van Puijvelde GHM, Kuiper J, Foks AC
Cardiovasc Res, 116(2):295-305, 01 Feb 2020
Cited by: 16 articles | PMID: 31150053
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Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis.
Kritikou E, Depuydt MAC, de Vries MR, Mulder KE, Govaert AM, Smit MD, van Duijn J, Foks AC, Wezel A, Smeets HJ, Slütter B, Quax PHA, Kuiper J, Bot I
Cells, 8(4):E334, 09 Apr 2019
Cited by: 15 articles | PMID: 30970663 | PMCID: PMC6523866
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Increased lymphocyte activation and atherosclerosis in CD47-deficient mice.
Engelbertsen D, Autio A, Verwilligen RAF, Depuydt MAC, Newton G, Rattik S, Levinsohn E, Saggu G, Jarolim P, Wang H, Velazquez F, Lichtman AH, Luscinskas FW
Sci Rep, 9(1):10608, 23 Jul 2019
Cited by: 26 articles | PMID: 31337788 | PMCID: PMC6650435
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Elimination of adrenocortical apolipoprotein E production does not impact glucocorticoid output in wild-type mice.
van der Sluis RJ, Depuydt MAC, Verwilligen RAF, Hoekstra M, Van Eck M
Mol Cell Endocrinol, 490:21-27, 03 Apr 2019
Cited by: 0 articles | PMID: 30953750
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IL-23R Deficiency Does Not Impact Atherosclerotic Plaque Development in Mice.
Engelbertsen D, Depuydt MAC, Verwilligen RAF, Rattik S, Levinsohn E, Edsfeldt A, Kuperwaser F, Jarolim P, Lichtman AH
J Am Heart Assoc, 7(8):e008257, 04 Apr 2018
Cited by: 12 articles | PMID: 29618473 | PMCID: PMC6015431
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