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Transcriptional Responses of Pseudomonas aeruginosa to Inhibition of Lipoprotein Transport by a Small Molecule Inhibitor.
Lorenz C, Dougherty TJ, Lory S
J Bacteriol, 202(24):e00452-20, 19 Nov 2020
Cited by: 2 articles | PMID: 32989085 | PMCID: PMC7685553
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Correct Sorting of Lipoproteins into the Inner and Outer Membranes of Pseudomonas aeruginosa by the Escherichia coli LolCDE Transport System.
Lorenz C, Dougherty TJ, Lory S
mBio, 10(2):e00194-19, 16 Apr 2019
Cited by: 9 articles | PMID: 30992347 | PMCID: PMC6469965
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Transcriptional Responses of Escherichia coli to a Small-Molecule Inhibitor of LolCDE, an Essential Component of the Lipoprotein Transport Pathway.
Lorenz C, Dougherty TJ, Lory S
J Bacteriol, 198(23):3162-3175, 04 Nov 2016
Cited by: 13 articles | PMID: 27645386 | PMCID: PMC5105897
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Editorial overview: Antimicrobials: fighting bacterial infections in the 21st century-thinking outside of the box.
Pucci MJ, Dougherty TJ
Curr Opin Microbiol, 33:v-vii, 24 Aug 2016
Cited by: 1 article | PMID: 27567402
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Novel antibacterial targets and compounds revealed by a high-throughput cell wall reporter assay.
Nayar AS, Dougherty TJ, Ferguson KE, Granger BA, McWilliams L, Stacey C, Leach LJ, Narita S, Tokuda H, Miller AA, Brown DG, McLeod SM
J Bacteriol, 197(10):1726-1734, 02 Mar 2015
Cited by: 59 articles | PMID: 25733621 | PMCID: PMC4402386
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Target-based resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a novel bacterial type II topoisomerase inhibitor.
Nayar AS, Dougherty TJ, Reck F, Thresher J, Gao N, Shapiro AB, Ehmann DE
Antimicrob Agents Chemother, 59(1):331-337, 27 Oct 2014
Cited by: 15 articles | PMID: 25348539 | PMCID: PMC4291369
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Optimization of physicochemical properties and safety profile of novel bacterial topoisomerase type II inhibitors (NBTIs) with activity against Pseudomonas aeruginosa.
Reck F, Ehmann DE, Dougherty TJ, Newman JV, Hopkins S, Stone G, Agrawal N, Ciaccio P, McNulty J, Barthlow H, O'Donnell J, Goteti K, Breen J, Comita-Prevoir J, Cornebise M, Cronin M, Eyermann CJ, Geng B, Carr GR, [...] Bezdenejnih-Snyder N
Bioorg Med Chem, 22(19):5392-5409, 04 Aug 2014
Cited by: 8 articles | PMID: 25155913
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NBTI 5463 is a novel bacterial type II topoisomerase inhibitor with activity against gram-negative bacteria and in vivo efficacy.
Dougherty TJ, Nayar A, Newman JV, Hopkins S, Stone GG, Johnstone M, Shapiro AB, Cronin M, Reck F, Ehmann DE
Antimicrob Agents Chemother, 58(5):2657-2664, 24 Feb 2014
Cited by: 29 articles | PMID: 24566174 | PMCID: PMC3993248
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Photodynamic therapy (PDT) using HPPH for the treatment of precancerous lesions associated with Barrett's esophagus.
Nava HR, Allamaneni SS, Dougherty TJ, Cooper MT, Tan W, Wilding G, Henderson BW
Lasers Surg Med, 43(7):705-712, 01 Sep 2011
Cited by: 31 articles | PMID: 22057498 | PMCID: PMC3218433
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Introduction.
Dougherty TJ
Methods Mol Biol, 635:1-6, 01 Jan 2010
Cited by: 3 articles | PMID: 20552336
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Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.
Magee TV, Ripp SL, Li B, Buzon RA, Chupak L, Dougherty TJ, Finegan SM, Girard D, Hagen AE, Falcone MJ, Farley KA, Granskog K, Hardink JR, Huband MD, Kamicker BJ, Kaneko T, Knickerbocker MJ, Liras JL, Marra A, [...] Flanagan ME
J Med Chem, 52(23):7446-7457, 01 Dec 2009
Cited by: 18 articles | PMID: 19775168
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Purification of the large ribosomal subunit via its association with the small subunit.
Simons SP, McLellan TJ, Aeed PA, Zaniewski RP, Desbonnet CR, Wondrack LM, Marr ES, Subashi TA, Dougherty TJ, Xu Z, Wang IK, LeMotte PK, Maguire BA
Anal Biochem, 395(1):77-85, 30 Jul 2009
Cited by: 4 articles | PMID: 19646947
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Comparative genome analysis of high-level penicillin resistance in Streptococcus pneumoniae.
Tait-Kamradt AG, Cronan M, Dougherty TJ
Microb Drug Resist, 15(2):69-75, 01 Jun 2009
Cited by: 11 articles | PMID: 19432519
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Photodynamic therapy for the treatment of periocular squamous cell carcinoma in horses: a pilot study.
Giuliano EA, MacDonald I, McCaw DL, Dougherty TJ, Klauss G, Ota J, Pearce JW, Johnson PJ
Vet Ophthalmol, 11 Suppl 1:27-34, 01 Sep 2008
Cited by: 11 articles | PMID: 19046267
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Identification of an inhibitor of the MurC enzyme, which catalyzes an essential step in the peptidoglycan precursor synthesis pathway.
Zawadzke LE, Norcia M, Desbonnet CR, Wang H, Freeman-Cook K, Dougherty TJ
Assay Drug Dev Technol, 6(1):95-103, 01 Feb 2008
Cited by: 14 articles | PMID: 18315498
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A method to assay penicillin-binding proteins.
Pucci MJ, Dougherty TJ
Methods Mol Med, 142:131-141, 01 Jan 2008
Cited by: 1 article | PMID: 18437311
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Nucleotide sequence changes between Streptococcus pneumoniae R6 and D39 strains determined by an oligonucleotide hybridization DNA sequencing technology.
Williams SP, Tait-Kamradt AG, Norton JE, Albert TJ, Dougherty TJ
J Microbiol Methods, 70(1):65-74, 30 Mar 2007
Cited by: 5 articles | PMID: 17477996
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Purpurinimide carbohydrate conjugates: effect of the position of the carbohydrate moiety in photosensitizing efficacy.
Pandey SK, Zheng X, Morgan J, Missert JR, Liu TH, Shibata M, Bellnier DA, Oseroff AR, Henderson BW, Dougherty TJ, Pandey RK
Mol Pharm, 4(3):448-464, 21 Mar 2007
Cited by: 23 articles | PMID: 17373821
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Extensive and genome-wide changes in the transcription profile of Staphylococcus aureus induced by modulating the transcription of the cell wall synthesis gene murF.
Sobral RG, Jones AE, Des Etages SG, Dougherty TJ, Peitzsch RM, Gaasterland T, Ludovice AM, de Lencastre H, Tomasz A
J Bacteriol, 189(6):2376-2391, 28 Dec 2006
Cited by: 48 articles | PMID: 17194794 | PMCID: PMC1899396
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Cyclopentanone ring-cleaved pleuromutilin derivatives.
Springer DM, Bunker A, Luh BY, Sorenson ME, Goodrich JT, Bronson JJ, DenBleyker K, Dougherty TJ, Fung-Tomc J
Eur J Med Chem, 42(1):109-113, 06 Dec 2006
Cited by: 6 articles | PMID: 17156897
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Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy.
Pandey RK, Goswami LN, Chen Y, Gryshuk A, Missert JR, Oseroff A, Dougherty TJ
Lasers Surg Med, 38(5):445-467, 01 Jun 2006
Cited by: 60 articles | PMID: 16788930
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Clinical pharmacokinetics of the PDT photosensitizers porfimer sodium (Photofrin), 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (Photochlor) and 5-ALA-induced protoporphyrin IX.
Bellnier DA, Greco WR, Loewen GM, Nava H, Oseroff AR, Dougherty TJ
Lasers Surg Med, 38(5):439-444, 01 Jun 2006
Cited by: 36 articles | PMID: 16634075
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A dose ranging study of photodynamic therapy with porfimer sodium (Photofrin) for treatment of basal cell carcinoma.
Oseroff AR, Blumenson LR, Wilson BD, Mang TS, Bellnier DA, Parsons JC, Frawley N, Cooper M, Zeitouni N, Dougherty TJ
Lasers Surg Med, 38(5):417-426, 01 Jun 2006
Cited by: 18 articles | PMID: 16788928
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Microbial genomics and drug discovery: exploring innovative routes of drug discovery in the postgenomic era.
Dougherty TJ, Miller PF
IDrugs, 9(6):420-422, 01 Jun 2006
Cited by: 5 articles | PMID: 16752312
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Mild skin photosensitivity in cancer patients following injection of Photochlor (2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a; HPPH) for photodynamic therapy.
Bellnier DA, Greco WR, Nava H, Loewen GM, Oseroff AR, Dougherty TJ
Cancer Chemother Pharmacol, 57(1):40-45, 05 Nov 2005
Cited by: 49 articles | PMID: 16001178
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