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Search life-sciences literature (45,104,145 articles, preprints and more)

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Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen.
Drabison T, Boeckman M, Yang Y, Huang KM, de Bruijn P, Nepal MR, Silvaroli JA, Chowdhury AT, Eisenmann ED, Cheng X, Pabla N, Mathijssen RHJ, Baker SD, Hu S, Sparreboom A, Talebi Z
Cancer Res Commun, 4(9):2489-2497, 01 Sep 2024
Cited by: 0 articles | PMID: 39207193 | PMCID: PMC11417675
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Pharmacokinetic assessment of low dose decitabine in combination therapies: Development and validation of a sensitive UHPLC-MS/MS method for murine plasma analysis.
Anabtawi N, Drabison T, Jin Y, Eisenmann ED, Sparreboom A, Govindarajan R, Baker SD, Ahmed E
J Chromatogr B Analyt Technol Biomed Life Sci, 1242:124209, 14 Jun 2024
Cited by: 0 articles | PMID: 38905720
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Darolutamide does not interfere with OATP-mediated uptake of docetaxel.
Buck SAJ, Talebi Z, Drabison T, Jin Y, Gibson AA, Hu P, de Bruijn P, de Ridder CMA, Stuurman D, Hu S, van Weerden WM, Koolen SLW, de Wit R, Sparreboom A, Mathijssen RHJ, Eisenmann ED
Int J Cancer, 155(2):314-323, 16 Mar 2024
Cited by: 1 article | PMID: 38491867
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Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice.
Li Y, Kazuki Y, Drabison T, Kobayashi K, Fujita KI, Xu Y, Jin Y, Ahmed E, Li J, Eisenmann ED, Baker SD, Cavaletti G, Sparreboom A, Hu S
Drug Metab Dispos, 52(2):80-85, 09 Jan 2024
Cited by: 0 articles | PMID: 38071551
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Unique Cabozantinib Dosing Considerations in People Living with HIV and Cancer.
Eisenmann ED, Sparreboom A
Clin Cancer Res, 29(24):4999-5001, 01 Dec 2023
Cited by: 0 articles | PMID: 37792442
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Exploring pharmacokinetics of talazoparib in ABCB1/ABCG2-deficient mice using a novel UHPLC-MS/MS method.
Talebi Z, Garrison DA, Eisenmann ED, Parmar K, Shapiro GI, Rudek MA, Sparreboom A, Jin Y
Heliyon, 9(11):e20972, 13 Oct 2023
Cited by: 0 articles | PMID: 37908705 | PMCID: PMC10613910
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MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia.
Uddin ME, Eisenmann ED, Li Y, Huang KM, Garrison DA, Talebi Z, Gibson AA, Jin Y, Nepal M, Bonilla IM, Fu Q, Sun X, Millar A, Tarasov M, Jay CE, Cui X, Einolf HJ, Pelis RM, Smith SA, [...] Sparreboom A
Int J Mol Sci, 23(15):8607, 03 Aug 2022
Cited by: 2 articles | PMID: 35955741 | PMCID: PMC9369325
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TP-0903 Is Active in Preclinical Models of Acute Myeloid Leukemia with TP53 Mutation/Deletion.
Eisenmann ED, Stromatt JC, Fobare S, Huang KM, Buelow DR, Orwick S, Jeon JY, Weber RH, Larsen B, Mims AS, Hertlein E, Byrd JC, Baker SD
Cancers (Basel), 15(1):29, 21 Dec 2022
Cited by: 3 articles | PMID: 36612026 | PMCID: PMC9817780
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Itraconazole-Induced Increases in Gilteritinib Exposure Are Mediated by CYP3A and OATP1B.
Garrison DA, Jin Y, Talebi Z, Hu S, Sparreboom A, Baker SD, Eisenmann ED
Molecules, 27(20):6815, 12 Oct 2022
Cited by: 3 articles | PMID: 36296409 | PMCID: PMC9610999
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BMX kinase mediates gilteritinib resistance in FLT3-mutated AML through microenvironmental factors.
Buelow DR, Bhatnagar B, Orwick SJ, Jeon JY, Eisenmann ED, Stromatt JC, Pabla NS, Blachly JS, Baker SD, Blaser BW
Blood Adv, 6(17):5049-5060, 01 Sep 2022
Cited by: 3 articles | PMID: 35797240 | PMCID: PMC9631628
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Determination of the endogenous OATP1B biomarkers glycochenodeoxycholate-3-sulfate and chenodeoxycholate-24-glucuronide in human and mouse plasma by a validated UHPLC-MS/MS method.
Jin Y, Li Y, Eisenmann ED, Figg WD, Baker SD, Sparreboom A, Hu S
J Chromatogr B Analyt Technol Biomed Life Sci, 1210:123437, 27 Aug 2022
Cited by: 3 articles | PMID: 36054985 | PMCID: PMC9588625
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A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug-Drug Interaction Liabilities.
Li Y, Jin Y, Taheri H, Schmidt KT, Gibson AA, Buck SAJ, Eisenmann ED, Mathijssen RHJ, Figg WD, Baker SD, Sparreboom A, Hu S
Pharmaceutics, 14(9):1933, 13 Sep 2022
Cited by: 0 articles | PMID: 36145680 | PMCID: PMC9502272
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Interaction of Antifungal Drugs with CYP3A- and OATP1B-Mediated Venetoclax Elimination.
Eisenmann ED, Garrison DA, Talebi Z, Jin Y, Silvaroli JA, Kim JG, Sparreboom A, Savona MR, Mims AS, Baker SD
Pharmaceutics, 14(4):694, 23 Mar 2022
Cited by: 9 articles | PMID: 35456528 | PMCID: PMC9025810
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Intentional Modulation of Ibrutinib Pharmacokinetics through CYP3A Inhibition.
Eisenmann ED, Fu Q, Muhowski EM, Jin Y, Uddin ME, Garrison DA, Weber RH, Woyach J, Byrd JC, Sparreboom A, Baker SD
Cancer Res Commun, 1(2):79-89, 09 Nov 2021
Cited by: 4 articles | PMID: 34950932 | PMCID: PMC8691714
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Boosting the oral bioavailability of anticancer drugs through intentional drug-drug interactions.
Eisenmann ED, Talebi Z, Sparreboom A, Baker SD
Basic Clin Pharmacol Toxicol, 130 Suppl 1:23-35, 28 Jun 2021
Cited by: 16 articles | PMID: 34117715 | PMCID: PMC8665934
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Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1.
Uddin ME, Garrison DA, Kim K, Jin Y, Eisenmann ED, Huang KM, Gibson AA, Hu Z, Sparreboom A, Hu S
Front Pharmacol, 12:644342, 08 Mar 2021
Cited by: 11 articles | PMID: 33790797 | PMCID: PMC8006202
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Targeting OCT3 attenuates doxorubicin-induced cardiac injury.
Huang KM, Zavorka Thomas M, Magdy T, Eisenmann ED, Uddin ME, DiGiacomo DF, Pan A, Keiser M, Otter M, Xia SH, Li Y, Jin Y, Fu Q, Gibson AA, Bonilla IM, Carnes CA, Corps KN, Coppola V, Smith SA, [...] Sparreboom A
Proc Natl Acad Sci U S A, 118(5):e2020168118, 01 Feb 2021
Cited by: 25 articles | PMID: 33495337 | PMCID: PMC7865186
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TP-0903 is active in models of drug-resistant acute myeloid leukemia.
Jeon JY, Buelow DR, Garrison DA, Niu M, Eisenmann ED, Huang KM, Zavorka Thomas ME, Weber RH, Whatcott CJ, Warner SL, Orwick SJ, Carmichael B, Stahl E, Brinton LT, Lapalombella R, Blachly JS, Hertlein E, Byrd JC, Bhatnagar B, Baker SD
JCI Insight, 5(23):140169, 03 Dec 2020
Cited by: 13 articles | PMID: 33268594 | PMCID: PMC7714403
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Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice.
Huang KM, Leblanc AF, Uddin ME, Kim JY, Chen M, Eisenmann ED, Gibson AA, Li Y, Hong KW, DiGiacomo D, Xia SH, Alberti P, Chiorazzi A, Housley SN, Cope TC, Sprowl JA, Wang J, Loprinzi CL, Noonan A, [...] Sparreboom A
J Clin Invest, 130(9):4601-4606, 01 Sep 2020
Cited by: 32 articles | PMID: 32484793 | PMCID: PMC7456253
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Influence of Probenecid on the Pharmacokinetics and Pharmacodynamics of Sorafenib.
Hussaarts KGAM, van Doorn L, Eechoute K, Damman J, Fu Q, van Doorn N, Eisenmann ED, Gibson AA, Oomen-de Hoop E, de Bruijn P, Baker SD, Koolen SLW, van Gelder T, van Leeuwen RWF, Mathijssen RHJ, Sparreboom A, Bins S
Pharmaceutics, 12(9):E788, 20 Aug 2020
Cited by: 7 articles | PMID: 32825359 | PMCID: PMC7559746
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Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors.
Garrison DA, Talebi Z, Eisenmann ED, Sparreboom A, Baker SD
Pharmaceutics, 12(9):E856, 09 Sep 2020
Cited by: 18 articles | PMID: 32916864 | PMCID: PMC7559291
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Development and validation of a sensitive UHPLC-MS/MS analytical method for venetoclax in mouse plasma, and its application to pharmacokinetic studies.
Eisenmann ED, Jin Y, Weber RH, Sparreboom A, Baker SD
J Chromatogr B Analyt Technol Biomed Life Sci, 1152:122176, 20 May 2020
Cited by: 6 articles | PMID: 32534260
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Sorafenib Population Pharmacokinetics and Skin Toxicities in Children and Adolescents with Refractory/Relapsed Leukemia or Solid Tumor Malignancies.
Inaba H, Panetta JC, Pounds SB, Wang L, Li L, Navid F, Federico SM, Eisenmann ED, Vasilyeva A, Wang YD, Shurtleff S, Pui CH, Gruber TA, Ribeiro RC, Rubnitz JE, Baker SD
Clin Cancer Res, 25(24):7320-7330, 27 Aug 2019
Cited by: 8 articles | PMID: 31455680 | PMCID: PMC6911639
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Myocardial hypersensitivity to ischemic injury is not reversed by clonidine or propranolol in a predator-based rat model of posttraumatic stress disorder.
Rorabaugh BR, Bui AD, Seeley SL, Eisenmann ED, Rose RM, Johnson BL, Huntley MR, Heikkila ME, Zoladz PR
Prog Neuropsychopharmacol Biol Psychiatry, 89:117-124, 05 Sep 2018
Cited by: 3 articles | PMID: 30194949 | PMCID: PMC6249040
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Predator-based psychosocial stress model of PTSD differentially influences voluntary ethanol consumption depending on methodology.
Zoladz PR, Eisenmann ED, Rose RM, Kohls BA, Johnson BL, Robinson KL, Heikkila ME, Mucher KE, Huntley MR
Alcohol, 70:33-41, 08 Jan 2018
Cited by: 6 articles | PMID: 29775837
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1-25 of 28 results

1 2

Search life-sciences literature (45,104,145 articles, preprints and more)

Search results

Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen.

Pharmacokinetic assessment of low dose decitabine in combination therapies: Development and validation of a sensitive UHPLC-MS/MS method for murine plasma analysis.

Darolutamide does not interfere with OATP-mediated uptake of docetaxel.

Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice.

Unique Cabozantinib Dosing Considerations in People Living with HIV and Cancer.

Exploring pharmacokinetics of talazoparib in ABCB1/ABCG2-deficient mice using a novel UHPLC-MS/MS method.

MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia.

TP-0903 Is Active in Preclinical Models of Acute Myeloid Leukemia with TP53 Mutation/Deletion.

Itraconazole-Induced Increases in Gilteritinib Exposure Are Mediated by CYP3A and OATP1B.

BMX kinase mediates gilteritinib resistance in FLT3-mutated AML through microenvironmental factors.

Determination of the endogenous OATP1B biomarkers glycochenodeoxycholate-3-sulfate and chenodeoxycholate-24-glucuronide in human and mouse plasma by a validated UHPLC-MS/MS method.

A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug-Drug Interaction Liabilities.

Interaction of Antifungal Drugs with CYP3A- and OATP1B-Mediated Venetoclax Elimination.

Intentional Modulation of Ibrutinib Pharmacokinetics through CYP3A Inhibition.

Boosting the oral bioavailability of anticancer drugs through intentional drug-drug interactions.

Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1.

Targeting OCT3 attenuates doxorubicin-induced cardiac injury.

TP-0903 is active in models of drug-resistant acute myeloid leukemia.

Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice.

Influence of Probenecid on the Pharmacokinetics and Pharmacodynamics of Sorafenib.

Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors.

Development and validation of a sensitive UHPLC-MS/MS analytical method for venetoclax in mouse plasma, and its application to pharmacokinetic studies.

Sorafenib Population Pharmacokinetics and Skin Toxicities in Children and Adolescents with Refractory/Relapsed Leukemia or Solid Tumor Malignancies.

Myocardial hypersensitivity to ischemic injury is not reversed by clonidine or propranolol in a predator-based rat model of posttraumatic stress disorder.

Predator-based psychosocial stress model of PTSD differentially influences voluntary ethanol consumption depending on methodology.

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