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Search life-sciences literature (45,100,050 articles, preprints and more)

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Alternative cGAS signaling promotes Herpes simplex encephalitis
Shmuel-Galia L, Jiang Z, Stine L, Cahill S, Ng S, Wilson R, Kandasamy RK, Kurt-Jones E, Ramanjulu J, Bertin J, Kasparcova V, Pesiridis S, Fitzgerald KA, Humphries F
bioRxiv, 15 Nov 2024
Cited by: 0 articles | PPR: PPR940897
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Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.
Jena KK, Mambu J, Boehmer D, Sposito B, Millet V, de Sousa Casal J, Muendlein HI, Spreafico R, Fenouil R, Spinelli L, Wurbel S, Riquier C, Galland F, Naquet P, Chasson L, Elkins M, Mitsialis V, Ketelut-Carneiro N, Gwilt KB, [...] Zanoni I
Cell, S0092-8674(24)01158-9, 30 Oct 2024
Cited by: 0 articles | PMID: 39500322
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Amphiphile-engineered DNA adjuvants stimulate strong type I IFN production in lymph nodes via cytosolic danger-sensing to induce potent cellular and humoral immunity in mice and non-human primates
Steinbuck MP, Seenappa LM, Zhan W, Palmer E, Jakubowski A, Cabana-Puig X, Jung MM, McNeil LK, Haqq CM, Fitzgerald KA, DeMuth PC
bioRxiv, 03 Nov 2024
Cited by: 0 articles | PPR: PPR934298
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Quantifying and mitigating motor phenotypes induced by antisense oligonucleotides in the central nervous system.
Moazami MP, Rembetsy-Brown JM, Sarli SL, McEachern HR, Wang F, Ohara M, Wagh A, Kelly K, Krishnamurthy PM, Weiss A, Marosfoi M, King RM, Motwani M, Gray-Edwards H, Fitzgerald KA, Brown RH, Watts JK
Mol Ther, S1525-0016(24)00684-1, 28 Oct 2024
Cited by: 2 articles | PMID: 39460376
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DNA-sensing pathways in health, autoinflammatory and autoimmune diseases.
Dong M, Fitzgerald KA
Nat Immunol, 25(11):2001-2014, 04 Oct 2024
Cited by: 0 articles | PMID: 39367124
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer.
Chibaya L, DeMarco KD, Lusi CF, Kane GI, Brassil ML, Parikh CN, Murphy KC, Chowdhury SR, Li J, Ma B, Naylor TE, Cerrutti J, Mori H, Diaz-Infante M, Peura J, Pitarresi JR, Zhu LJ, Fitzgerald KA, Atukorale PU, Ruscetti M
Sci Transl Med, 16(762):eadj9366, 28 Aug 2024
Cited by: 2 articles | PMID: 39196958
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CRISPR editing of candidate host factors that impact influenza A virus infection
Kyawe PP, Liu P, Jiang Z, Bradley ES, Cicuto T, Trombly MI, Silverman N, Fitzgerald KA, McDougall WM, Wang JP
bioRxiv, 11 Sep 2024
Cited by: 0 articles | PPR: PPR909722
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Unmasking immune suppression.
Pitarresi JR, Fitzgerald KA
Science, 385(6705):140-142, 11 Jul 2024
Cited by: 0 articles | PMID: 38991086
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Activation of autoreactive lymphocytes in the lung by radioresistant cells expressing a STING gain-of-function mutation.
Gao KM, Chiang K, Subramanian S, Yin X, Utz PJ, Nündel K, Fitzgerald KA, Marshak-Rothstein A
JCI Insight, 9(16):e174331, 18 Jul 2024
Cited by: 0 articles | PMID: 39024563 | PMCID: PMC11343592
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Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration.
Gao KM, Chiang K, Jiang Z, Korkmaz FT, Janardhan HP, Trivedi CM, Quinton LJ, Gingras S, Fitzgerald KA, Marshak-Rothstein A
Cell Rep, 43(4):114114, 15 Apr 2024
Cited by: 6 articles | PMID: 38625791
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Differential Viral Dynamics by Sex and Body Mass Index During Acute SARS-CoV-2 Infection: Results From a Longitudinal Cohort Study.
Herbert C, Manabe YC, Filippaios A, Lin H, Wang B, Achenbach C, Kheterpal V, Hartin P, Suvarna T, Harman E, Stamegna P, Rao LV, Hafer N, Broach J, Luzuriaga K, Fitzgerald KA, McManus DD, Soni A
Clin Infect Dis, 78(5):1185-1193, 01 May 2024
Cited by: 2 articles | PMID: 37972270 | PMCID: PMC11093673
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Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease.
Johnson JL, Sargsyan D, Neiman EM, Hart A, Stojmirovic A, Kosoy R, Irizar H, Suárez-Fariñas M, Song WM, Argmann C, Avey S, Shmuel-Galia L, Vierbuchen T, Bongers G, Sun Y, Edelstein L, Perrigoue J, Towne JE, Hall AO, [...] Hoebe K
JCI Insight, 9(3):e168988, 08 Feb 2024
Cited by: 1 article | PMID: 38329124 | PMCID: PMC10967393
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Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells.
Ramalho T, Assis PA, Ojelabi O, Tan L, Carvalho B, Gardinassi L, Campos O, Lorenzi PL, Fitzgerald KA, Haynes C, Golenbock DT, Gazzinelli RT
Cell Metab, 36(3):484-497.e6, 06 Feb 2024
Cited by: 4 articles | PMID: 38325373
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Lnc-ing RNA to intestinal homeostasis and inflammation.
Fitzgerald KA, Shmuel-Galia L
Trends Immunol, 45(2):127-137, 13 Jan 2024
Cited by: 2 articles | PMID: 38220553
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The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection.
Pereira M, Ramalho T, Andrade WA, Durso DF, Souza MC, Fitzgerald KA, Golenbock DT, Silverman N, Gazzinelli RT
Cell Rep, 43(2):113795, 15 Feb 2024
Cited by: 1 article | PMID: 38367238 | PMCID: PMC11559090
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Measuring Emergency Department Staff Perceptions of Causes and Management of Violence.
Ewen J, Gaeta L, Fitzgerald KA, Ragione BL, Feil DA, Feil DA, Raio CC, Arrillaga A, Klein LR, Eckardt PA
J Trauma Nurs, 30(6):307-317, 01 Nov 2023
Cited by: 0 articles | PMID: 37937869
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Cellular nucleic acid-binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA-protein condensates.
Chen Y, Lei X, Jiang Z, Humphries F, Parsi KM, Mustone NJ, Ramos I, Mutetwa T, Fernandez-Sesma A, Maehr R, Caffrey DR, Fitzgerald KA
Proc Natl Acad Sci U S A, 120(47):e2308355120, 14 Nov 2023
Cited by: 4 articles | PMID: 37963251 | PMCID: PMC10666094
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Stream hydrology and a pulse subsidy shape patterns of fish foraging.
Fitzgerald KA, Bellmore JR, Fellman JB, Cheng MLH, Delbecq CE, Falke JA
J Anim Ecol, 92(12):2386-2398, 30 Oct 2023
Cited by: 0 articles | PMID: 37904340
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Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancer
Chibaya L, Lusi CF, DeMarco KD, Kane GI, Brassil ML, Parikh CN, Murphy KC, Li J, Naylor TE, Cerrutti J, Peura J, Pitarresi JR, Zhu LJ, Fitzgerald KA, Atukorale PU, Ruscetti M
bioRxiv, 18 Sep 2023
Cited by: 0 articles | PPR: PPR727193
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STING channels its proton power.
Dong M, Fitzgerald KA
Mol Cell, 83(19):3402-3403, 01 Oct 2023
Cited by: 0 articles | PMID: 37802022
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Development of LB244, an Irreversible STING Antagonist.
Barasa L, Chaudhuri S, Zhou JY, Jiang Z, Choudhary S, Green RM, Wiggin E, Cameron M, Humphries F, Fitzgerald KA, Thompson PR
J Am Chem Soc, 145(37):20273-20288, 11 Sep 2023
Cited by: 4 articles | PMID: 37695732 | PMCID: PMC11059204
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Targeting STING oligomerization with small-molecule inhibitors.
Humphries F, Shmuel-Galia L, Jiang Z, Zhou JY, Barasa L, Mondal S, Wilson R, Sultana N, Shaffer SA, Ng SL, Pesiridis GS, Thompson PR, Fitzgerald KA
Proc Natl Acad Sci U S A, 120(33):e2305420120, 07 Aug 2023
Cited by: 12 articles | PMID: 37549268 | PMCID: PMC10434303
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Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs
Gao KM, Chiang K, Korkmaz FT, Janardhan HP, Trivedi CM, Quinton LJ, Gingras S, Fitzgerald KA, Marshak-Rothstein A
bioRxiv, 27 Jul 2023
Cited by: 0 articles | PPR: PPR699197
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The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis.
Shmuel-Galia L, Humphries F, Vierbuchen T, Jiang Z, Santos N, Johnson J, Shklyar B, Joannas L, Mustone N, Sherman S, Ward D, Houghton J, Baer CE, O'Hara A, Henao-Mejia J, Hoebe K, Fitzgerald KA
Cell Metab, 35(8):1441-1456.e9, 25 Jul 2023
Cited by: 4 articles | PMID: 37494932
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Content Validity and Psychometric Evaluation of the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) in Patients with Crohn's Disease and Ulcerative Colitis.
Loftus EV, Ananthakrishnan AN, Lee WJ, Gonzalez YS, Fitzgerald KA, Wallace K, Zhou W, Litcher-Kelly L, Ollis SB, Su S, Danese S
Pharmacoecon Open, 7(5):823-840, 09 Jun 2023
Cited by: 3 articles | PMID: 37296268 | PMCID: PMC10471538
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