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Search life-sciences literature (45,104,206 articles, preprints and more)

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Inflammasome activation aggravates choroidal neovascularization.
Makin RD, Apicella I, Dholkawala R, Fukuda S, Hirahara S, Hirano Y, Kim Y, Nagasaka A, Nagasaka Y, Narendran S, Pereira F, Varshney A, Wang SB, Ambati J, Gelfand BD
Angiogenesis, 27(4):919-929, 24 Sep 2024
Cited by: 0 articles | PMID: 39316206 | PMCID: PMC11563918
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Disruption of the <i>Uty</i> epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure.
Horitani K, Chavkin NW, Arai Y, Wang Y, Ogawa H, Yura Y, Evans MA, Cochran JD, Thel MC, Polizio AH, Sano M, Miura-Yura E, Arai Y, Doviak H, Arnold AP, Gelfand BD, Hirschi KK, Sano S, Walsh K
Nat Cardiovasc Res, 3(3):343-355, 08 Mar 2024
Cited by: 1 article | PMID: 39183958 | PMCID: PMC11343478
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Effects of donor-specific microvascular anatomy on hemodynamic perfusion in human choriocapillaris.
An S, Yu H, Islam MDM, Zhang X, Zhan Y, Olivieri JJ, Ambati J, Yao J, Gelfand BD
Sci Rep, 13(1):22666, 19 Dec 2023
Cited by: 1 article | PMID: 38114564 | PMCID: PMC10730623
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Haloperidol inhibits inflammasome activation via LAMTOR1 and reduces the risk of arthritides
Ambati VL, Yerramothu P, Konduri R, Nguyen J, Gelfand BD, Taylor EW, Werner BC, Wang S
medRxiv, 08 Dec 2023
Cited by: 0 articles | PPR: PPR770632
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Y chromosome proteins in female tissues.
Gelfand BD, Ambati J
Science, 382(6666):39-40, 05 Oct 2023
Cited by: 3 articles | PMID: 37797018 | PMCID: PMC11554370
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Survey of commercial antibodies targeting Y chromosome-encoded genes.
Gelfand BD, Argyle DA, Olivieri JJ, Ambati J
MedComm Futur Med, 2(4):e62, 03 Oct 2023
Cited by: 0 articles | PMID: 38645476
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Survey of commercial antibodies targeting Y chromosome-encoded genes
Gelfand BD, Argyle DA, Olivieri JJ, Ambati J
bioRxiv, 27 Jul 2023
Cited by: 0 articles | PPR: PPR699206
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Reduction of human Alzheimer’s disease risk and reversal of mouse model cognitive deficit with nucleoside analog use
Magagnoli J, Yerramothu P, Ambati K, Cummings T, Nguyen J, Thomas CC, Wang S, Cheng K, Juraev M, Dholkawala R, Nagasaka A, Ambati M, Nagasaka Y, Ban A, Ambati VL, Sutton SS, Gelfand BD, Ambati J
medRxiv, 21 Mar 2023
Cited by: 0 articles | PPR: PPR633674
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Kamuvudine-9 Protects Retinal Structure and Function in a Novel Model of Experimental Rhegmatogenous Retinal Detachment.
Huang P, Thomas CC, Ambati K, Dholkawala R, Nagasaka A, Yerramothu P, Narendran S, Pereira F, Nagasaka Y, Apicella I, Cai X, Makin RD, Magagnoli J, Stains CI, Yin R, Wang SB, Gelfand BD, Ambati J
Invest Ophthalmol Vis Sci, 64(5):3, 01 May 2023
Cited by: 1 article | PMID: 37129905 | PMCID: PMC10158986
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Response to 'Early Onset Drusen and RPE Dysfunction in a Patient with NLRP3-AID'.
Ambati J, Gelfand BD
Ocul Immunol Inflamm, 32(5):778, 12 Apr 2023
Cited by: 0 articles | PMID: 37043599
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Targeting the m6A mRNA demethylase FTO suppresses vascular endothelial growth factor release and choroidal neovascularization.
Wang SB, Nagasaka Y, Argyle D, Nagasaka A, Yerramothu P, Gelfand BD, Ambati J
Signal Transduct Target Ther, 8(1):72, 20 Feb 2023
Cited by: 5 articles | PMID: 36801892 | PMCID: PMC9939410
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Subretinal injection in mice to study retinal physiology and disease.
Huang P, Narendran S, Pereira F, Fukuda S, Nagasaka Y, Apicella I, Yerramothu P, Marion KM, Cai X, Sadda SR, Gelfand BD, Ambati J
Nat Protoc, 17(6):1468-1485, 13 Apr 2022
Cited by: 3 articles | PMID: 35418688 | PMCID: PMC11146522
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The Learning Curve of Murine Subretinal Injection Among Clinically Trained Ophthalmic Surgeons.
Huang P, Narendran S, Pereira F, Fukuda S, Nagasaka Y, Apicella I, Yerramothu P, Marion KM, Cai X, Sadda SR, Gelfand BD, Ambati J
Transl Vis Sci Technol, 11(3):13, 01 Mar 2022
Cited by: 3 articles | PMID: 35275207 | PMCID: PMC8934552
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Compartmentalized citrullination in Muller glial endfeet during retinal degeneration.
Palko SI, Saba NJ, Mullane E, Nicholas BD, Nagasaka Y, Ambati J, Gelfand BD, Ishigami A, Bargagna-Mohan P, Mohan R
Proc Natl Acad Sci U S A, 119(9):e2121875119, 01 Mar 2022
Cited by: 14 articles | PMID: 35197297 | PMCID: PMC8917347
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A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling.
Banerjee D, Langberg K, Abbas S, Odermatt E, Yerramothu P, Volaric M, Reidenbach MA, Krentz KJ, Rubinstein CD, Brautigan DL, Abbas T, Gelfand BD, Ambati J, Kerur N
Nat Commun, 12(1):6207, 27 Oct 2021
Cited by: 29 articles | PMID: 34707113 | PMCID: PMC8551335
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The learning curve of murine subretinal injection among clinically trained ophthalmic surgeons
Huang P, Narendran S, Pereira F, Fukuda S, Nagasaka Y, Apicella I, Yerramothu P, Marion KM, Cai X, Sadda SR, Gelfand BD, Ambati J
bioRxiv, 08 Nov 2021
Cited by: 0 articles | PPR: PPR417470
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Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration.
Ambati M, Apicella I, Wang SB, Narendran S, Leung H, Pereira F, Nagasaka Y, Huang P, Varshney A, Baker KL, Marion KM, Shadmehr M, Stains CI, Werner BC, Sadda SR, Taylor EW, Sutton SS, Magagnoli J, Gelfand BD
Proc Natl Acad Sci U S A, 118(41):e2102975118, 01 Oct 2021
Cited by: 25 articles | PMID: 34620711 | PMCID: PMC8522269
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DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.
Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, [...] Ambati J
Sci Immunol, 6(66):eabi4493, 03 Dec 2021
Cited by: 23 articles | PMID: 34860583 | PMCID: PMC8767314
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Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity.
Fukuda S, Narendran S, Varshney A, Nagasaka Y, Wang SB, Ambati K, Apicella I, Pereira F, Fowler BJ, Yasuma T, Hirahara S, Yasuma R, Huang P, Yerramothu P, Makin RD, Wang M, Baker KL, Marion KM, Huang X, [...] Ambati J
Sci Adv, 7(40):eabj3658, 29 Sep 2021
Cited by: 21 articles | PMID: 34586848 | PMCID: PMC8480932
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Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration.
Narendran S, Pereira F, Yerramothu P, Apicella I, Wang SB, Ambati K, Hirahara S, Kim Y, Ambati M, Ambati VL, Huang P, Varshney A, Nagasaka Y, Fukuda S, Baker KL, Marion KM, Deussing JM, Sadda SR, Gelfand BD, Ambati J
Signal Transduct Target Ther, 6(1):149, 14 Apr 2021
Cited by: 13 articles | PMID: 33850097 | PMCID: PMC8044134
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Identification of Fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration
Ambati M, Apicella I, Narendran S, Wang S, Leung H, Pereira F, Varshney A, Baker KL, Marion KM, Shadmehr M, Stains CI, Sadda SR, Taylor EW, Sutton SS, Werner BC, Magagnoli J, Gelfand BD
bioRxiv, 12 Jan 2021
Cited by: 0 articles | PPR: PPR264224
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Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration.
Fukuda S, Varshney A, Fowler BJ, Wang SB, Narendran S, Ambati K, Yasuma T, Magagnoli J, Leung H, Hirahara S, Nagasaka Y, Yasuma R, Apicella I, Pereira F, Makin RD, Magner E, Liu X, Sun J, Wang M, [...] Ambati J
Proc Natl Acad Sci U S A, 118(6):e2022751118, 01 Feb 2021
Cited by: 32 articles | PMID: 33526699 | PMCID: PMC8017980
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A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration.
Narendran S, Pereira F, Yerramothu P, Apicella I, Wang SB, Varshney A, Baker KL, Marion KM, Ambati M, Ambati VL, Ambati K, Sadda SR, Gelfand BD, Ambati J
Invest Ophthalmol Vis Sci, 61(10):4, 01 Aug 2020
Cited by: 11 articles | PMID: 32749462 | PMCID: PMC7441363
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Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development.
Ambati J, Magagnoli J, Leung H, Wang SB, Andrews CA, Fu D, Pandey A, Sahu S, Narendran S, Hirahara S, Fukuda S, Sun J, Pandya L, Ambati M, Pereira F, Varshney A, Cummings T, Hardin JW, Edun B, [...] Gelfand BD
Nat Commun, 11(1):4737, 23 Sep 2020
Cited by: 23 articles | PMID: 32968070 | PMCID: PMC7511405
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Voluntary Exercise Suppresses Choroidal Neovascularization in Mice.
Makin RD, Argyle D, Hirahara S, Nagasaka Y, Zhang M, Yan Z, Kerur N, Ambati J, Gelfand BD
Invest Ophthalmol Vis Sci, 61(5):52, 01 May 2020
Cited by: 5 articles | PMID: 32460310 | PMCID: PMC7405794
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1-25 of 47 results

1 2

Search life-sciences literature (45,104,206 articles, preprints and more)

Search results

Inflammasome activation aggravates choroidal neovascularization.

Disruption of the <i>Uty</i> epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure.

Effects of donor-specific microvascular anatomy on hemodynamic perfusion in human choriocapillaris.

Haloperidol inhibits inflammasome activation via LAMTOR1 and reduces the risk of arthritides

Y chromosome proteins in female tissues.

Survey of commercial antibodies targeting Y chromosome-encoded genes.

Survey of commercial antibodies targeting Y chromosome-encoded genes

Reduction of human Alzheimer’s disease risk and reversal of mouse model cognitive deficit with nucleoside analog use

Kamuvudine-9 Protects Retinal Structure and Function in a Novel Model of Experimental Rhegmatogenous Retinal Detachment.

Response to 'Early Onset Drusen and RPE Dysfunction in a Patient with NLRP3-AID'.

Targeting the m6A mRNA demethylase FTO suppresses vascular endothelial growth factor release and choroidal neovascularization.

Subretinal injection in mice to study retinal physiology and disease.

The Learning Curve of Murine Subretinal Injection Among Clinically Trained Ophthalmic Surgeons.

Compartmentalized citrullination in Muller glial endfeet during retinal degeneration.

A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling.

The learning curve of murine subretinal injection among clinically trained ophthalmic surgeons

Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration.

DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.

Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity.

Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration.

Identification of Fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration

Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration.

A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration.

Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development.

Voluntary Exercise Suppresses Choroidal Neovascularization in Mice.

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