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Search life-sciences literature (45,104,206 articles, preprints and more)

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Pillars Article: Molecular Cloning of cDNA Encoding a Murine Haematopoietic Growth Regulator, Granulocyte-Macrophage Colony Stimulating Factor. Nature. 1984. 309: 763-767.
Gough NM, Gough J, Metcalf D, Kelso A, Grail D, Nicola NA, Burgess AW, Dunn AR
J Immunol, 198(7):2522-2526, 01 Apr 2017
Cited by: 0 articles | PMID: 28320912
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STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.
Ernst M, Najdovska M, Grail D, Lundgren-May T, Buchert M, Tye H, Matthews VB, Armes J, Bhathal PS, Hughes NR, Marcusson EG, Karras JG, Na S, Sedgwick JD, Hertzog PJ, Jenkins BJ
J Clin Invest, 118(5):1727-1738, 01 May 2008
Cited by: 226 articles | PMID: 18431520 | PMCID: PMC2323192
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IL-6 regulates neutrophil trafficking during acute inflammation via STAT3.
Fielding CA, McLoughlin RM, McLeod L, Colmont CS, Najdovska M, Grail D, Ernst M, Jones SA, Topley N, Jenkins BJ
J Immunol, 181(3):2189-2195, 01 Aug 2008
Cited by: 244 articles | PMID: 18641358
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Mice lacking both G-CSF and IL-6 are more susceptible to Candida albicans infection: critical role of neutrophils in defense against Candida albicans.
Basu S, Quilici C, Zhang HH, Grail D, Dunn AR
Growth Factors, 26(1):23-34, 01 Feb 2008
Cited by: 29 articles | PMID: 18365876
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Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.
Jenkins BJ, Grail D, Nheu T, Najdovska M, Wang B, Waring P, Inglese M, McLoughlin RM, Jones SA, Topley N, Baumann H, Judd LM, Giraud AS, Boussioutas A, Zhu HJ, Ernst M
Nat Med, 11(8):845-852, 24 Jul 2005
Cited by: 201 articles | PMID: 16041381
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Pathologic consequences of STAT3 hyperactivation by IL-6 and IL-11 during hematopoiesis and lymphopoiesis.
Jenkins BJ, Roberts AW, Greenhill CJ, Najdovska M, Lundgren-May T, Robb L, Grail D, Ernst M
Blood, 109(6):2380-2388, 02 Nov 2006
Cited by: 55 articles | PMID: 17082315
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Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferation.
Yeoh GC, Ernst M, Rose-John S, Akhurst B, Payne C, Long S, Alexander W, Croker B, Grail D, Matthews VB
Hepatology, 45(2):486-494, 01 Feb 2007
Cited by: 69 articles | PMID: 17256754
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IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.
McLoughlin RM, Jenkins BJ, Grail D, Williams AS, Fielding CA, Parker CR, Ernst M, Topley N, Jones SA
Proc Natl Acad Sci U S A, 102(27):9589-9594, 23 Jun 2005
Cited by: 204 articles | PMID: 15976028 | PMCID: PMC1172246
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Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.
Howlett M, Judd LM, Jenkins B, La Gruta NL, Grail D, Ernst M, Giraud AS
Gastroenterology, 129(3):1005-1018, 01 Sep 2005
Cited by: 43 articles | PMID: 16143138
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Vascular endothelial growth factor D is dispensable for development of the lymphatic system.
Baldwin ME, Halford MM, Roufail S, Williams RA, Hibbs ML, Grail D, Kubo H, Stacker SA, Achen MG
Mol Cell Biol, 25(6):2441-2449, 01 Mar 2005
Cited by: 165 articles | PMID: 15743836 | PMCID: PMC1061605
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The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis.
Jenkins BJ, Roberts AW, Najdovska M, Grail D, Ernst M
Blood, 105(9):3512-3520, 13 Jan 2005
Cited by: 54 articles | PMID: 15650055
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Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos.
Stenvers KL, Tursky ML, Harder KW, Kountouri N, Amatayakul-Chantler S, Grail D, Small C, Weinberg RA, Sizeland AM, Zhu HJ
Mol Cell Biol, 23(12):4371-4385, 01 Jun 2003
Cited by: 146 articles | PMID: 12773577 | PMCID: PMC156130
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Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy.
Kaczmarczyk SJ, Andrikopoulos S, Favaloro J, Domenighetti AA, Dunn A, Ernst M, Grail D, Fodero-Tavoletti M, Huggins CE, Delbridge LM, Zajac JD, Proietto J
J Mol Endocrinol, 31(3):449-459, 01 Dec 2003
Cited by: 35 articles | PMID: 14664706
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Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.
Jenkins BJ, Grail D, Inglese M, Quilici C, Bozinovski S, Wong P, Ernst M
Mol Cell Biol, 24(4):1453-1463, 01 Feb 2004
Cited by: 28 articles | PMID: 14749363 | PMCID: PMC344172
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Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.
Judd LM, Alderman BM, Howlett M, Shulkes A, Dow C, Moverley J, Grail D, Jenkins BJ, Ernst M, Giraud AS
Gastroenterology, 126(1):196-207, 01 Jan 2004
Cited by: 123 articles | PMID: 14699500
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Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling.
Jenkins BJ, Quilici C, Roberts AW, Grail D, Dunn AR, Ernst M
Exp Hematol, 30(11):1248-1256, 01 Nov 2002
Cited by: 16 articles | PMID: 12423677
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Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice.
Tebbutt NC, Giraud AS, Inglese M, Jenkins B, Waring P, Clay FJ, Malki S, Alderman BM, Grail D, Hollande F, Heath JK, Ernst M
Nat Med, 8(10):1089-1097, 09 Sep 2002
Cited by: 305 articles | PMID: 12219085
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Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sites.
Gugasyan R, Quilici C, I ST, Grail D, Verhagen AM, Roberts A, Kitamura T, Dunn AR, Lock P
J Cell Biol, 158(1):115-125, 01 Jul 2002
Cited by: 27 articles | PMID: 12093790 | PMCID: PMC2173016
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This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
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Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage.
Harder KW, Parsons LM, Armes J, Evans N, Kountouri N, Clark R, Quilici C, Grail D, Hodgson GS, Dunn AR, Hibbs ML
Immunity, 15(4):603-615, 01 Oct 2001
Cited by: 115 articles | PMID: 11672542
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Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk.
Halford MM, Armes J, Buchert M, Meskenaite V, Grail D, Hibbs ML, Wilks AF, Farlie PG, Newgreen DF, Hovens CM, Stacker SA
Nat Genet, 25(4):414-418, 01 Aug 2000
Cited by: 116 articles | PMID: 10932185
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Functional deficiencies of peritoneal cells from gene-targeted mice lacking G-CSF or GM-CSF.
Zhan Y, Basu S, Lieschke GJ, Grail D, Dunn AR, Cheers C
J Leukoc Biol, 65(2):256-264, 01 Feb 1999
Cited by: 13 articles | PMID: 10088609
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Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice.
Campbell IK, Rich MJ, Bischof RJ, Dunn AR, Grail D, Hamilton JA
J Immunol, 161(7):3639-3644, 01 Oct 1998
Cited by: 147 articles | PMID: 9759887
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Characterization of tumor necrosis factor-deficient mice.
Marino MW, Dunn A, Grail D, Inglese M, Noguchi Y, Richards E, Jungbluth A, Wada H, Moore M, Williamson B, Basu S, Old LJ
Proc Natl Acad Sci U S A, 94(15):8093-8098, 01 Jul 1997
Cited by: 482 articles | PMID: 9223320 | PMCID: PMC21562
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Essential roles for granulocyte-macrophage colony-stimulating factor (GM-CSF) and G-CSF in the sustained hematopoietic response of Listeria monocytogenes-infected mice.
Zhan Y, Lieschke GJ, Grail D, Dunn AR, Cheers C
Blood, 91(3):863-869, 01 Feb 1998
Cited by: 106 articles | PMID: 9446646
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Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor.
Horwood NJ, Udagawa N, Elliott J, Grail D, Okamura H, Kurimoto M, Dunn AR, Martin T, Gillespie MT
J Clin Invest, 101(3):595-603, 01 Feb 1998
Cited by: 122 articles | PMID: 9449693 | PMCID: PMC508603
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1-25 of 42 results

1 2

Search life-sciences literature (45,104,206 articles, preprints and more)

Search results

Pillars Article: Molecular Cloning of cDNA Encoding a Murine Haematopoietic Growth Regulator, Granulocyte-Macrophage Colony Stimulating Factor. Nature. 1984. 309: 763-767.

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

IL-6 regulates neutrophil trafficking during acute inflammation via STAT3.

Mice lacking both G-CSF and IL-6 are more susceptible to Candida albicans infection: critical role of neutrophils in defense against Candida albicans.

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

Pathologic consequences of STAT3 hyperactivation by IL-6 and IL-11 during hematopoiesis and lymphopoiesis.

Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferation.

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.

Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.

Vascular endothelial growth factor D is dispensable for development of the lymphatic system.

The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis.

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos.

Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy.

Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.

Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.

Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling.

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice.

Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sites.

Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage.

Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk.

Functional deficiencies of peritoneal cells from gene-targeted mice lacking G-CSF or GM-CSF.

Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice.

Characterization of tumor necrosis factor-deficient mice.

Essential roles for granulocyte-macrophage colony-stimulating factor (GM-CSF) and G-CSF in the sustained hematopoietic response of Listeria monocytogenes-infected mice.

Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor.

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