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Search life-sciences literature (45,100,050 articles, preprints and more)

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Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort.
Carapito R, Li R, Helms J, Carapito C, Gujja S, Rolli V, Guimaraes R, Malagon-Lopez J, Spinnhirny P, Lederle A, Mohseninia R, Hirschler A, Muller L, Bastard P, Gervais A, Zhang Q, Danion F, Ruch Y, Schenck M, [...] Bahram S
Sci Transl Med, 14(628):eabj7521, 19 Jan 2022
Cited by: 63 articles | PMID: 34698500
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Identification of driver genes for severe forms of COVID-19 in a deeply phenotyped young patient cohort
Carapito R, Li R, Helms J, Carapito C, Gujja S, Rolli V, Guimaraes R, Malagon-Lopez J, Spinnhirny P, Mohseninia R, Hirschler A, Muller L, Bastard P, Gervais A, Zhang Q, Danion F, Ruch Y, Schenck-Dhif M, Collange O, [...] Bahram S
medRxiv, 25 Jun 2021
Cited by: 0 articles | PPR: PPR361554
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Quantum processor-inspired machine learning in the biomedical sciences.
Li RY, Gujja S, Bajaj SR, Gamel OE, Cilfone N, Gulcher JR, Lidar DA, Chittenden TW
Patterns (N Y), 2(6):100246, 28 Apr 2021
Cited by: 3 articles | PMID: 34179840 | PMCID: PMC8212142
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In silico phenotype projection of endothelial ERK1/2 signaling.
Simons M, Gulcher JR, Chittenden TW
Aging (Albany NY), 12(11):10001-10003, 12 Jun 2020
Cited by: 0 articles | PMID: 32530820 | PMCID: PMC7346033
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Chronic mTOR activation induces a degradative smooth muscle cell phenotype.
Li G, Wang M, Caulk AW, Cilfone NA, Gujja S, Qin L, Chen PY, Chen Z, Yousef S, Jiao Y, He C, Jiang B, Korneva A, Bersi MR, Wang G, Liu X, Mehta S, Geirsson A, Gulcher JR, [...] Tellides G
J Clin Invest, 130(3):1233-1251, 01 Mar 2020
Cited by: 46 articles | PMID: 32039915 | PMCID: PMC7269581
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Smooth Muscle Cell Reprogramming in Aortic Aneurysms.
Chen PY, Qin L, Li G, Malagon-Lopez J, Wang Z, Bergaya S, Gujja S, Caulk AW, Murtada SI, Zhang X, Zhuang ZW, Rao DA, Wang G, Tobiasova Z, Jiang B, Montgomery RR, Sun L, Sun H, Fisher EA, [...] Simons M
Cell Stem Cell, 26(4):542-557.e11, 01 Apr 2020
Cited by: 99 articles | PMID: 32243809 | PMCID: PMC7182079
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Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium.
Ricard N, Scott RP, Booth CJ, Velazquez H, Cilfone NA, Baylon JL, Gulcher JR, Quaggin SE, Chittenden TW, Simons M
J Exp Med, 216(8):1874-1890, 13 Jun 2019
Cited by: 33 articles | PMID: 31196980 | PMCID: PMC6683988
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Enhancing Retrosynthetic Reaction Prediction with Deep Learning Using Multiscale Reaction Classification.
Baylon JL, Cilfone NA, Gulcher JR, Chittenden TW
J Chem Inf Model, 59(2):673-688, 01 Feb 2019
Cited by: 20 articles | PMID: 30642173
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Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.
Ayers KL, Glicksberg BS, Garfield AS, Longerich S, White JA, Yang P, Du L, Chittenden TW, Gulcher JR, Roy S, Fiedorek F, Gottesdiener K, Cohen S, North KE, Schadt EE, Li SD, Chen R, Van der Ploeg LHT
J Clin Endocrinol Metab, 103(7):2601-2612, 01 Jul 2018
Cited by: 32 articles | PMID: 29726959 | PMCID: PMC7263790
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Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C, [...] Fox CS
Nat Commun, 7:10023, 21 Jan 2016
Cited by: 323 articles | PMID: 26831199 | PMCID: PMC4735748
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Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community.
Kaess BM, Preis SR, Lieb W, Beiser AS, Yang Q, Chen TC, Hengstenberg C, Erdmann J, Schunkert H, Seshadri S, Vasan RS, CARDIoGRAM, Assimes TL, Deloukas P, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, [...] Stewart AF
J Am Heart Assoc, 4(3):e001544, 11 Mar 2015
Cited by: 81 articles | PMID: 25762803 | PMCID: PMC4392437
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A common biological basis of obesity and nicotine addiction.
Thorgeirsson TE, Gudbjartsson DF, Sulem P, Besenbacher S, Styrkarsdottir U, Thorleifsson G, Walters GB, TAG Consortium, Oxford-GSK Consortium, ENGAGE consortium, Furberg H, Sullivan PF, Marchini J, McCarthy MI, Steinthorsdottir V, Thorsteinsdottir U, Stefansson K
Transl Psychiatry, 3:e308, 01 Oct 2013
Cited by: 31 articles | PMID: 24084939 | PMCID: PMC3818010
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Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels.
Holmes MV, Exeter HJ, Folkersen L, Nelson CP, Guardiola M, Cooper JA, Sofat R, Boekholdt SM, Khaw KT, Li KW, Smith AJ, Van't Hooft F, Eriksson P, Franco-Cereceda A, Asselbergs FW, Boer JM, Onland-Moret NC, Hofker M, Erdmann J, [...] CARDIoGRAM Consortium
Circ Cardiovasc Genet, 7(2):144-150, 21 Feb 2014
Cited by: 17 articles | PMID: 24563418 | PMCID: PMC4212409
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Genetic predisposition to higher blood pressure increases coronary artery disease risk.
Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP, Assimes TL, Boerwinkle E, Hall AS, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson JR, König IR, [...] CARDIoGRAM
Hypertension, 61(5):995-1001, 11 Mar 2013
Cited by: 53 articles | PMID: 23478099 | PMCID: PMC3855241
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Dysfunctional nitric oxide signalling increases risk of myocardial infarction.
Erdmann J, Stark K, Esslinger UB, Rumpf PM, Koesling D, de Wit C, Kaiser FJ, Braunholz D, Medack A, Fischer M, Zimmermann ME, Tennstedt S, Graf E, Eck S, Aherrahrou Z, Nahrstaedt J, Willenborg C, Bruse P, Brænne I, [...] Schunkert H
Nature, 504(7480):432-436, 10 Nov 2013
Cited by: 160 articles | PMID: 24213632
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Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.
Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ, CARDIoGRAM Consortium, CHARGE Inflammation Working Group, Dehghan A, Lu C, Levy D, Newton-Cheh C, [...] Wang TJ
J Clin Invest, 123(10):4208-4218, 03 Sep 2013
Cited by: 67 articles | PMID: 23999434 | PMCID: PMC3784527
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Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, Mälarstig A, Baumert J, Bis JC, Guo X, Hottenga JJ, Shin SY, Lopez LM, [...] O'Donnell CJ
Circulation, 128(12):1310-1324, 22 Aug 2013
Cited by: 101 articles | PMID: 23969696 | PMCID: PMC3842025
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Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.
Reiner AP, Hartiala J, Zeller T, Bis JC, Dupuis J, Fornage M, Baumert J, Kleber ME, Wild PS, Baldus S, Bielinski SJ, Fontes JD, Illig T, Keating BJ, Lange LA, Ojeda F, Müller-Nurasyid M, Munzel TF, Psaty BM, [...] Allayee H
Hum Mol Genet, 22(16):3381-3393, 24 Apr 2013
Cited by: 17 articles | PMID: 23620142 | PMCID: PMC3723315
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The shared allelic architecture of adiponectin levels and coronary artery disease.
Dastani Z, Johnson T, Kronenberg F, Nelson CP, Assimes TL, März W, CARDIoGRAM Consortium, ADIPOGen Consortium, Richards JB
Atherosclerosis, 229(1):145-148, 22 Apr 2013
Cited by: 25 articles | PMID: 23664276 | PMCID: PMC6139652
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A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer.
Gudmundsson J, Sulem P, Gudbjartsson DF, Masson G, Agnarsson BA, Benediktsdottir KR, Sigurdsson A, Magnusson OT, Gudjonsson SA, Magnusdottir DN, Johannsdottir H, Helgadottir HT, Stacey SN, Jonasdottir A, Olafsdottir SB, Thorleifsson G, Jonasson JG, Tryggvadottir L, Navarrete S, [...] Stefansson K
Nat Genet, 44(12):1326-1329, 28 Oct 2012
Cited by: 127 articles | PMID: 23104005 | PMCID: PMC3562711
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RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies.
Herder C, Peeters W, Illig T, Baumert J, de Kleijn DP, Moll FL, Poschen U, Klopp N, Müller-Nurasyid M, Roden M, Preuss M, CARDIoGRAM Consortium, Karakas M, Meisinger C, Thorand B, Pasterkamp G, Koenig W, Assimes TL, Deloukas P, [...] Stewart AF
PLoS One, 6(12):e25734, 06 Dec 2011
Cited by: 29 articles | PMID: 22162987 | PMCID: PMC3232218
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Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
O'Donnell CJ, Kavousi M, Smith AV, Kardia SL, Feitosa MF, Hwang SJ, Sun YV, Province MA, Aspelund T, Dehghan A, Hoffmann U, Bielak LF, Zhang Q, Eiriksdottir G, van Duijn CM, Fox CS, de Andrade M, Kraja AT, Sigurdsson S, [...] Witteman JC
Circulation, 124(25):2855-2864, 05 Dec 2011
Cited by: 196 articles | PMID: 22144573 | PMCID: PMC3397173
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Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.
Lu X, Wang L, Chen S, He L, Yang X, Shi Y, Cheng J, Zhang L, Gu CC, Huang J, Wu T, Ma Y, Li J, Cao J, Chen J, Ge D, Fan Z, Li Y, Zhao L, [...] Gu D
Nat Genet, 44(8):890-894, 01 Jul 2012
Cited by: 217 articles | PMID: 22751097 | PMCID: PMC3927410
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Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.
Clarke R, Bennett DA, Parish S, Verhoef P, Dötsch-Klerk M, Lathrop M, Xu P, Nordestgaard BG, Holm H, Hopewell JC, Saleheen D, Tanaka T, Anand SS, Chambers JC, Kleber ME, Ouwehand WH, Yamada Y, Elbers C, Peters B, [...] MTHFR Studies Collaborative Group
PLoS Med, 9(2):e1001177, 21 Feb 2012
Cited by: 112 articles | PMID: 22363213 | PMCID: PMC3283559
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Human metabolic individuality in biomedical and pharmaceutical research.
Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E, CARDIoGRAM, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, [...] Gieger C
Nature, 477(7362):54-60, 31 Aug 2011
Cited by: 649 articles | PMID: 21886157 | PMCID: PMC3832838
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1-25 of 137 results

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Search life-sciences literature (45,100,050 articles, preprints and more)

Search results

Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort.

Identification of driver genes for severe forms of COVID-19 in a deeply phenotyped young patient cohort

Quantum processor-inspired machine learning in the biomedical sciences.

In silico phenotype projection of endothelial ERK1/2 signaling.

Chronic mTOR activation induces a degradative smooth muscle cell phenotype.

Smooth Muscle Cell Reprogramming in Aortic Aneurysms.

Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium.

Enhancing Retrosynthetic Reaction Prediction with Deep Learning Using Multiscale Reaction Classification.

Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.

Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community.

A common biological basis of obesity and nicotine addiction.

Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels.

Genetic predisposition to higher blood pressure increases coronary artery disease risk.

Dysfunctional nitric oxide signalling increases risk of myocardial infarction.

Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.

The shared allelic architecture of adiponectin levels and coronary artery disease.

A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer.

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies.

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.

Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.

Human metabolic individuality in biomedical and pharmaceutical research.

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