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Search life-sciences literature (45,100,050 articles, preprints and more)

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Using QALYs as an Outcome for Assessing Global Prediction Accuracy in Diabetes Simulation Models.
Dakin HA, Gao N, Leal J, Holman RR, Tran-Duy A, Clarke P
Med Decis Making, 272989X241285866, 30 Oct 2024
Cited by: 0 articles | PMID: 39474832
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Younger-onset compared with later-onset type 2 diabetes: an analysis of the UK Prospective Diabetes Study (UKPDS) with up to 30 years of follow-up (UKPDS 92).
Lin B, Coleman RL, Bragg F, Maddaloni E, Holman RR, Adler AI
Lancet Diabetes Endocrinol, S2213-8587(24)00242-0, 22 Oct 2024
Cited by: 0 articles | PMID: 39461360
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Cardiovascular outcomes with exenatide in type 2 diabetes according to ejection fraction: The EXSCEL trial.
Neves JS, Leite AR, Mentz RJ, Holman RR, Zannad F, Butler J, Packer M, Ferreira JP
Eur J Heart Fail, 09 Oct 2024
Cited by: 0 articles | PMID: 39381950
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Great debate: pre-diabetes is not an evidence-based treatment target for cardiovascular risk reduction.
Marx N, Rydén L, Federici M, Marx-Schütt K, Verket M, Müller-Wieland D, Gerstein HC, Chan J, Cosentino F, Holman RR, Mellbin L, Ray KK, Standl E, Verma S, Wood D, Tuomilehto J, De Caterina R
Eur Heart J, ehae533, 10 Oct 2024
Cited by: 0 articles | PMID: 39387537
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Inflammatory proteins associated with Alzheimer's disease reduced by a GLP1 receptor agonist: a post hoc analysis of the EXSCEL randomized placebo controlled trial.
Koychev I, Reid G, Nguyen M, Mentz RJ, Joyce D, Shah SH, Holman RR
Alzheimers Res Ther, 16(1):212, 02 Oct 2024
Cited by: 0 articles | PMID: 39358806 | PMCID: PMC11448378
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Estimated glomerular filtration rate slope and risk of primary and secondary major adverse cardiovascular events and heart failure hospitalization in people with type 2 diabetes: An analysis of the EXSCEL trial.
Oulhaj A, Aziz F, Suliman A, Eller K, Bentoumi R, Buse JB, Al Mahmeed W, von Lewinski D, Coleman RL, Holman RR, Sourij H
Diabetes Obes Metab, 26(10):4602-4612, 31 Jul 2024
Cited by: 0 articles | PMID: 39086032
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Protocol for a double-blind placebo-controlled randomised controlled trial assessing the impact of oral semaglutide in amyloid positivity (ISAP) in community dwelling UK adults.
Koychev I, Adler AI, Edison P, Tom B, Milton JE, Butchart J, Hampshire A, Marshall C, Coulthard E, Zetterberg H, Hellyer P, Cormack F, Underwood BR, Mummery CJ, Holman RR
BMJ Open, 14(6):e081401, 21 Jun 2024
Cited by: 1 article | PMID: 38908839 | PMCID: PMC11328662
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Estimating Risk Factor Time Paths Among People with Type 2 Diabetes and QALY Gains from Risk Factor Management.
Gao N, Dakin HA, Holman RR, Lim LL, Leal J, Clarke P
Pharmacoeconomics, 42(9):1017-1028, 26 Jun 2024
Cited by: 0 articles | PMID: 38922488 | PMCID: PMC11344020
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Post-trial monitoring of a randomised controlled trial of intensive glycaemic control in type 2 diabetes extended from 10 years to 24 years (UKPDS 91).
Adler AI, Coleman RL, Leal J, Whiteley WN, Clarke P, Holman RR
Lancet, 404(10448):145-155, 18 May 2024
Cited by: 5 articles | PMID: 38772405
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Are the cardiovascular properties of GLP-1 receptor agonists differentially modulated by sulfonylureas? Insights from post-hoc analysis of EXSCEL.
Gooding KM, Stevens S, Lokhnygina Y, Giczewska A, Shore AC, Holman RR
Diabetes Res Clin Pract, 212:111685, 25 Apr 2024
Cited by: 0 articles | PMID: 38670496
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Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities
Loesch DP, Garg M, Matelska D, Vitsios D, Jiang X, Ritchie SC, Sun BB, Runz H, Whelan CD, Holman RR, Mentz RJ, Moura FA, Wiviott SD, Sabatine MS, Udler MS, Gause-Nilsson IA, Petrovski S, Oscarsson J, Nag A, [...] Inouye M
medRxiv, 19 Mar 2024
Cited by: 0 articles | PPR: PPR823775
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Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes.
Cardoso P, Young KG, Nair ATN, Hopkins R, McGovern AP, Haider E, Karunaratne P, Donnelly L, Mateen BA, Sattar N, Holman RR, Bowden J, Hattersley AT, Pearson ER, Jones AG, Shields BM, McKinley TJ, Dennis JM, MASTERMIND consortium
Diabetologia, 67(5):822-836, 22 Feb 2024
Cited by: 3 articles | PMID: 38388753 | PMCID: PMC10955037
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Regional variation in cause of death in patients with type 2 diabetes: Insights from EXSCEL.
Rao VN, Sharma A, Stebbins A, Buse JB, Katona BG, Pagidipati NJ, Holman RR, Hernandez A, Mentz RJ, Lopes RD
Am Heart J, 271:123-135, 22 Feb 2024
Cited by: 0 articles | PMID: 38395292
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Comparison of medical resources and costs among patients with coronary heart disease and impaired glucose tolerance in the Acarbose Cardiovascular Evaluation trial.
Morrow LM, Becker F, Coleman RL, Gerstein HC, Rydén L, Schöder S, Gray AM, Leal J, Holman RR, ACE Study Group
J Diabetes, 16(2):e13473, 01 Nov 2023
Cited by: 1 article | PMID: 37915263 | PMCID: PMC10859317
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Timing of SGLT2i initiation after acute myocardial infarction.
von Lewinski D, Kolesnik E, Aziz F, Benedikt M, Tripolt NJ, Wallner M, Pferschy PN, von Lewinski F, Schwegel N, Holman RR, Oulhaj A, Moertl D, Siller-Matula J, Sourij H
Cardiovasc Diabetol, 22(1):269, 30 Sep 2023
Cited by: 6 articles | PMID: 37777743 | PMCID: PMC10544140
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Orthostatic Hypotension, Hypertension Treatment, and Cardiovascular Disease: An Individual Participant Meta-Analysis.
Juraschek SP, Hu JR, Cluett JL, Ishak AM, Mita C, Lipsitz LA, Appel LJ, Beckett NS, Coleman RL, Cushman WC, Davis BR, Grandits G, Holman RR, Miller ER, Peters R, Staessen JA, Taylor AA, Thijs L, Wright JT, Mukamal KJ
JAMA, 330(15):1459-1471, 01 Oct 2023
Cited by: 4 articles | PMID: 37847274 | PMCID: PMC10582789
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Mitochondrial metabolites predict adverse cardiovascular events in individuals with diabetes.
Regan JA, Mentz RJ, Nguyen M, Green JB, Truby LK, Ilkayeva O, Newgard CB, Buse JB, Sourij H, Sjöström CD, Sattar N, McGarrah RW, Zheng Y, McGuire DK, Standl E, Armstrong P, Peterson ED, Hernandez AF, Holman RR, Shah SH
JCI Insight, 8(17):e168563, 08 Sep 2023
Cited by: 1 article | PMID: 37552540 | PMCID: PMC10544215
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Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes
Cardoso P, Young KG, Nair AT, Hopkins R, McGovern AP, Haider E, Karunaratne P, Donnelly L, Mateen BA, Sattar N, Holman RR, Bowden J, Hattersley AT, Pearson ER, Jones AG, Shields BM, McKinley TJ, Dennis JM
medRxiv, 08 Aug 2023
Cited by: 0 articles | PPR: PPR707009
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Aetiology of Type 2 diabetes in people with a 'normal' body mass index: testing the personal fat threshold hypothesis.
Taylor R, Barnes AC, Hollingsworth KG, Irvine KM, Solovyova AS, Clark L, Kelly T, Martin-Ruiz C, Romeres D, Koulman A, Meek CM, Jenkins B, Cobelli C, Holman RR
Clin Sci (Lond), 137(16):1333-1346, 01 Aug 2023
Cited by: 17 articles | PMID: 37593846 | PMCID: PMC10472166
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Proteomic Pathways across Ejection Fraction Spectrum in Heart Failure: an EXSCEL Substudy
Peters AE, Nguyen M, Green JB, Pearson ER, Buse J, Sourij H, Hernandez AF, Sattar N, Holman RR, Mentz RJ, Shah SH
medRxiv, 16 May 2023
Cited by: 0 articles | PPR: PPR660640
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Assessment of Cardiac Energy Metabolism, Function, and Physiology in Patients With Heart Failure Taking Empagliflozin: The Randomized, Controlled EMPA-VISION Trial.
Hundertmark MJ, Adler A, Antoniades C, Coleman R, Griffin JL, Holman RR, Lamlum H, Lee J, Massey D, Miller JJJJ, Milton JE, Monga S, Mózes FE, Nazeer A, Raman B, Rider O, Rodgers CT, Valkovič L, Wicks E, [...] Neubauer S
Circulation, 147(22):1654-1669, 18 Apr 2023
Cited by: 23 articles | PMID: 37070436 | PMCID: PMC10212585
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Time-dependent event accumulation in a cardiovascular outcome trial of patients with type 2 diabetes and established atherosclerotic cardiovascular disease.
Bethel MA, Sourij H, Stevens SR, Hannan K, Lokhnygina Y, Adler AI, Peterson ED, Holman RR, Lopes RD
Cardiovasc Diabetol, 22(1):72, 28 Mar 2023
Cited by: 0 articles | PMID: 36978066 | PMCID: PMC10054031
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Association of osteocalcin, osteoprotegerin, and osteopontin with cardiovascular disease and retinopathy in type 2 diabetes.
Maddaloni E, Coraggio L, Amendolara R, Baroni MG, Cavallo MG, Copetti M, Cossu E, D'Angelo P, D'Onofrio L, Cosmo S, Leonetti F, Morano S, Morviducci L, Napoli N, Prudente S, Pugliese G, Park K, Holman RR, Trischitta V, [...] SUMMER Study in Diabetes Group
Diabetes Metab Res Rev, 39(5):e3632, 20 Mar 2023
Cited by: 3 articles | PMID: 36880127
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11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial.
Othonos N, Pofi R, Arvaniti A, White S, Bonaventura I, Nikolaou N, Moolla A, Marjot T, Stimson RH, van Beek AP, van Faassen M, Isidori AM, Bateman E, Sadler R, Karpe F, Stewart PM, Webster C, Duffy J, Eastell R, [...] Tomlinson JW
Nat Commun, 14(1):1025, 23 Feb 2023
Cited by: 7 articles | PMID: 36823106 | PMCID: PMC9950480
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Sex differences in the complications, care and clinical outcomes of patients with type 2 diabetes in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).
Green JB, Merrill P, Lokhnygina Y, Mentz RJ, Alfredsson J, Holman RR, EXSCEL Study Group
Diabetes Obes Metab, 25(6):1473-1484, 14 Feb 2023
Cited by: 0 articles | PMID: 36700460
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