AUTH:"Horlings HM" - Search results

An explainable longitudinal multi-modal fusion model for predicting neoadjuvant therapy response in women with breast cancer.

Gao Y, Ventura-Diaz S, Wang X, He M, Xu Z, Weir A, Zhou HY, Zhang T, van Duijnhoven FH, Han L, Li X, D'Angelo A, Longo V, Liu Z, Teuwen J, Kok M, Beets-Tan R, Horlings HM, Tan T, Mann R

Nat Commun, 15(1):9613, 07 Nov 2024

Cited by: 0 articles | PMID: 39511143 | PMCID: PMC11544255

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Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.

Nederlof I, Isaeva OI, de Graaf M, Gielen RCAM, Bakker NAM, Rolfes AL, Garner H, Boeckx B, Traets JJH, Mandjes IAM, de Maaker M, van Brussel T, Chelushkin M, Champanhet E, Lopez-Yurda M, van de Vijver K, van den Berg JG, Hofland I, Klioueva N, [...] Kok M

Nat Med, 30(11):3223-3235, 16 Sep 2024

Cited by: 1 article | PMID: 39284953 | PMCID: PMC11564107

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High expression of phosphoglycerate dehydrogenase predicts poor outcome in patients with high-grade serous ovarian cancer.

van Wagensveld L, Van Nyen T, Annibali D, Sonke GS, Kruitwagen RFPM, Amant F, Horlings HM

Oncologist, 29(9):e1231-e1234, 01 Sep 2024

Cited by: 0 articles | PMID: 38920311 | PMCID: PMC11379630

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Tumor-Infiltrating Lymphocytes in Patients With Stage I Triple-Negative Breast Cancer Untreated With Chemotherapy.

Geurts VCM, Balduzzi S, Steenbruggen TG, Linn SC, Siesling S, Badve SS, DeMichele A, Ignatiadis M, Leon-Ferre RA, Goetz MP, Wolff AC, Klar N, Michiels S, Loi S, Adams S, Horlings HM, Sonke GS, Salgado R, Kok M

JAMA Oncol, 10(8):1077-1086, 01 Aug 2024

Cited by: 3 articles | PMID: 38935352

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Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial.

Opdam M, van Rossum AGJ, Hoogstraat M, Bounova G, Horlings HM, van Werkhoven E, Mandjes IAM, van Leeuwen-Stok AE, Canisius S, van Tinteren H, Imholz ALT, Portielje JEA, Bos MEMM, Bakker S, Wesseling J, Kester L, van Rheenen J, Rutgers EJ, de Menezes RX, [...] MATADOR trialists’ group for the Dutch Breast Cancer Research Group (BOOG)

iScience, 27(8):110425, 29 Jun 2024

Cited by: 0 articles | PMID: 39206149 | PMCID: PMC11357803

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Tumour microenvironment characterisation to stratify patients for hyperthermic intraperitoneal chemotherapy in high-grade serous ovarian cancer (OVHIPEC-1).

Aronson SL, Walker C, Thijssen B, van de Vijver KK, Horlings HM, Sanders J, Alkemade M, Koole SN, Lopez-Yurda M, Lok CAR, OVHIPEC-1 Study Group, Rottenberg S, van Rheenen J, Sonke GS, van Driel WJ, Kester LA, Hahn K

Br J Cancer, 131(3):565-576, 12 Jun 2024

Cited by: 0 articles | PMID: 38866963

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PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

Walker C, Talawalla T, Toth R, Ambekar A, Rea K, Chamian O, Fan F, Berezowska S, Rottenberg S, Madabhushi A, Maillard M, Barisoni L, Horlings HM, Janowczyk A

NPJ Digit Med, 7(1):164, 20 Jun 2024

Cited by: 0 articles | PMID: 38902336 | PMCID: PMC11190251

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Evaluating the effectiveness of pre-operative diagnosis of ovarian cancer using minimally invasive liquid biopsies by combining serum human epididymis protein 4 and cell-free DNA in patients with an ovarian mass.

Gaillard DHK, Lof P, Sistermans EA, Mokveld T, Horlings HM, Mom CH, Reinders MJT, Amant F, van den Broek D, Wessels LFA, Lok CAR, HE4 Study Group, Study group

Int J Gynecol Cancer, 34(5):713-721, 06 May 2024

Cited by: 0 articles | PMID: 38388177

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The Information Technology (IT) Infrastructure of the Multicenter Archipelago of Ovarian Cancer Research Biobank: A Potential Blueprint for Other Biobanks.

Zelisse HS, de Ridder S, van Gent MDJM, Mom CH, Wisman GBA, Roes EM, Reyners AKL, Piek JM, Nieuwenhuyzen-de Boer GM, Lok CAR, de Kroon CD, Kooreman LFS, Janssen MJ, Jansen MP, Horlings HM, Collée M, Broeks A, Boere IA, Bart J, [...] Archipelago of Ovarian Cancer Research Consortium

Biopreserv Biobank, 29 Apr 2024

Cited by: 0 articles | PMID: 38682281

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Tumor-infiltrating lymphocytes in HER2-positive breast cancer treated with neoadjuvant chemotherapy and dual HER2-blockade.

Liefaard MC, van der Voort A, van Seijen M, Thijssen B, Sanders J, Vonk S, Mittempergher L, Bhaskaran R, de Munck L, van Leeuwen-Stok AE, Salgado R, Horlings HM, Lips EH, Sonke GS

NPJ Breast Cancer, 10(1):29, 18 Apr 2024

Cited by: 4 articles | PMID: 38637568 | PMCID: PMC11026378

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Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.

Jahangir CA, Page DB, Broeckx G, Gonzalez CA, Burke C, Murphy C, Reis-Filho JS, Ly A, Harms PW, Gupta RR, Vieth M, Hida AI, Kahila M, Kos Z, van Diest PJ, Verbandt S, Thagaard J, Khiroya R, Abduljabbar K, [...] Rahman A

J Pathol, 262(3):271-288, 17 Jan 2024

Cited by: 2 articles | PMID: 38230434 | PMCID: PMC11288342

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PROACTING: predicting pathological complete response to neoadjuvant chemotherapy in breast cancer from routine diagnostic histopathology biopsies with deep learning.

Aswolinskiy W, Munari E, Horlings HM, Mulder L, Bogina G, Sanders J, Liu YH, van den Belt-Dusebout AW, Tessier L, Balkenhol M, Stegeman M, Hoven J, Wesseling J, van der Laak J, Lips EH, Ciompi F

Breast Cancer Res, 25(1):142, 13 Nov 2023

Cited by: 1 article | PMID: 37957667 | PMCID: PMC10644597

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Characterization of the Tumor Microenvironment of De Novo Oligometastatic Breast Cancer in a Nationwide Cohort.

Steenbruggen TG, Wolf DM, Thijssen B, Sanders J, Cornelissen S, Salgado R, Mittempergher L, Bhaskaran R, Broeks A, Lips EH, Siesling S, Sonke GS, Horlings HM, van 't Veer LJ

JCO Precis Oncol, 7:e2200670, 01 Sep 2023

Cited by: 0 articles | PMID: 37738542

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B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast cancer.

Steenbruggen TG, Wolf DM, Campbell MJ, Sanders J, Cornelissen S, Thijssen B, Salgado RA, Yau C, O-Grady N, Basu A, Bhaskaran R, Mittempergher L, Hirst GL, Coppe JP, Kok M, Sonke GS, van 't Veer LJ, Horlings HM

Breast Cancer Res, 25(1):117, 04 Oct 2023

Cited by: 2 articles | PMID: 37794508 | PMCID: PMC10552219

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CMTM6 shapes antitumor T cell response through modulating protein expression of CD58 and PD-L1.

Miao B, Hu Z, Mezzadra R, Hoeijmakers L, Fauster A, Du S, Yang Z, Sator-Schmitt M, Engel H, Li X, Broderick C, Jin G, Gomez-Eerland R, Rozeman L, Lei X, Matsuo H, Yang C, Hofland I, Peters D, [...] Sun C

Cancer Cell, 41(10):1817-1828.e9, 07 Sep 2023

Cited by: 6 articles | PMID: 37683639

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Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer

Thagaard J, Broeckx G, Page DB, Jahangir CA, Verbandt S, Kos Z, Gupta R, Khiroya R, Abduljabbar K, Acosta Haab G, Acs B, Akturk G, Almeida JS, Alvarado-Cabrero I, Amgad M, Azmoudeh-Ardalan F, Badve S, Baharun NB, Balslev E, [...] Specht Stovgaard E

J Pathol, 260(5):498-513, 23 Aug 2023

Cited by: 6 articles | PMID: 37608772 | PMCID: PMC10518802

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Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

Page DB, Broeckx G, Jahangir CA, Verbandt S, Gupta RR, Thagaard J, Khiroya R, Kos Z, Abduljabbar K, Acosta Haab G, Acs B, Akturk G, Almeida JS, Alvarado-Cabrero I, Azmoudeh-Ardalan F, Badve S, Baharun NB, Bellolio ER, Bheemaraju V, [...] Specht Stovgaard E

J Pathol, 260(5):514-532, 23 Aug 2023

Cited by: 2 articles | PMID: 37608771 | PMCID: PMC11288334

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BluePrint molecular subtypes predict response to neoadjuvant pertuzumab in HER2-positive breast cancer.

Liefaard MC, van der Voort A, van Ramshorst MS, Sanders J, Vonk S, Horlings HM, Siesling S, de Munck L, van Leeuwen AE, Kleijn M, Mittempergher L, Kuilman MM, Glas AM, Wesseling J, Lips EH, Sonke GS

Breast Cancer Res, 25(1):71, 19 Jun 2023

Cited by: 0 articles | PMID: 37337299 | PMCID: PMC10280902

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RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease.

Zhang T, Tan T, Wang X, Gao Y, Han L, Balkenende L, D'Angelo A, Bao L, Horlings HM, Teuwen J, Beets-Tan RGH, Mann RM

Cell Rep Med, 4(8):101131, 24 Jul 2023

Cited by: 3 articles | PMID: 37490915 | PMCID: PMC10439251

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Immune landscape of breast tumors with low and intermediate estrogen receptor expression.

Voorwerk L, Sanders J, Keusters MS, Balduzzi S, Cornelissen S, Duijst M, Lips EH, Sonke GS, Linn SC, Horlings HM, Kok M

NPJ Breast Cancer, 9(1):39, 13 May 2023

Cited by: 11 articles | PMID: 37179445 | PMCID: PMC10182974

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Unleashing NK- and CD8 T cells by combining monalizumab and trastuzumab for metastatic HER2-positive breast cancer: Results of the MIMOSA trial.

Geurts VCM, Voorwerk L, Balduzzi S, Salgado R, Van de Vijver K, van Dongen MGJ, Kemper I, Mandjes IAM, Heuver M, Sparreboom W, Haanen JBAG, Sonke GS, Horlings HM, Kok M

Breast, 70:76-81, 27 Jun 2023

Cited by: 8 articles | PMID: 37393645 | PMCID: PMC10336326

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Predicting breast cancer types on and beyond molecular level in a multi-modal fashion.

Zhang T, Tan T, Han L, Appelman L, Veltman J, Wessels R, Duvivier KM, Loo C, Gao Y, Wang X, Horlings HM, Beets-Tan RGH, Mann RM

NPJ Breast Cancer, 9(1):16, 22 Mar 2023

Cited by: 9 articles | PMID: 36949047 | PMCID: PMC10033710

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PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial.

Voorwerk L, Isaeva OI, Horlings HM, Balduzzi S, Chelushkin M, Bakker NAM, Champanhet E, Garner H, Sikorska K, Loo CE, Kemper I, Mandjes IAM, de Maaker M, van Geel JJL, Boers J, de Boer M, Salgado R, van Dongen MGJ, Sonke GS, [...] Kok M

Nat Cancer, 4(4):535-549, 10 Apr 2023

Cited by: 7 articles | PMID: 37038006 | PMCID: PMC10132987

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Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

Boshuizen J, Vredevoogd DW, Krijgsman O, Ligtenberg MA, Blankenstein S, de Bruijn B, Frederick DT, Kenski JCN, Parren M, Brüggemann M, Madu MF, Rozeman EA, Song JY, Horlings HM, Blank CU, van Akkooi ACJ, Flaherty KT, Boland GM, Peeper DS

Nat Commun, 14(1):672, 07 Feb 2023

Cited by: 0 articles | PMID: 36750559 | PMCID: PMC9905532

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CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.

Kang EY, Weir A, Meagher NS, Farrington K, Nelson GS, Ghatage P, Lee CH, Riggan MJ, Bolithon A, Popovic G, Leung B, Tang K, Lambie N, Millstein J, Alsop J, Anglesio MS, Ataseven B, Barlow E, Beckmann MW, [...] Köbel M

Cancer, 129(5):697-713, 26 Dec 2022

Cited by: 9 articles | PMID: 36572991 | PMCID: PMC10107112

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An explainable longitudinal multi-modal fusion model for predicting neoadjuvant therapy response in women with breast cancer.

Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.

High expression of phosphoglycerate dehydrogenase predicts poor outcome in patients with high-grade serous ovarian cancer.

Tumor-Infiltrating Lymphocytes in Patients With Stage I Triple-Negative Breast Cancer Untreated With Chemotherapy.

Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial.

Tumour microenvironment characterisation to stratify patients for hyperthermic intraperitoneal chemotherapy in high-grade serous ovarian cancer (OVHIPEC-1).

PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

Evaluating the effectiveness of pre-operative diagnosis of ovarian cancer using minimally invasive liquid biopsies by combining serum human epididymis protein 4 and cell-free DNA in patients with an ovarian mass.

The Information Technology (IT) Infrastructure of the Multicenter Archipelago of Ovarian Cancer Research Biobank: A Potential Blueprint for Other Biobanks.

Tumor-infiltrating lymphocytes in HER2-positive breast cancer treated with neoadjuvant chemotherapy and dual HER2-blockade.

Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.

PROACTING: predicting pathological complete response to neoadjuvant chemotherapy in breast cancer from routine diagnostic histopathology biopsies with deep learning.

Characterization of the Tumor Microenvironment of De Novo Oligometastatic Breast Cancer in a Nationwide Cohort.

B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast cancer.

CMTM6 shapes antitumor T cell response through modulating protein expression of CD58 and PD-L1.

Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer

Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

BluePrint molecular subtypes predict response to neoadjuvant pertuzumab in HER2-positive breast cancer.

RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease.

Immune landscape of breast tumors with low and intermediate estrogen receptor expression.

Unleashing NK- and CD8 T cells by combining monalizumab and trastuzumab for metastatic HER2-positive breast cancer: Results of the MIMOSA trial.

Predicting breast cancer types on and beyond molecular level in a multi-modal fashion.

PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial.

Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.

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