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Search life-sciences literature (45,104,206 articles, preprints and more)

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Individual Patient Data Analysis of Liver Lesion Dynamics: A Pan Cancer Analysis
Dickinson J, Huber HJ, Mistry HB
bioRxiv, 30 Oct 2024
Cited by: 0 articles | PPR: PPR932641
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In Silico Treatment: a computational framework for animal model selection and drug assessment
Picart-Armada S, Becker K, Kaestle M, Krenkel O, Simon E, Tenbaum S, Strobel B, Geillinger-Kaestle K, Fundel-Clemens K, Matera D, Lincoln K, Hill J, Viollet C, Streicher R, Thomas M, Jensen JN, Haslinger C, Klein H, Werner M, [...] Fernandez-Albert F
bioRxiv, 17 Jun 2024
Cited by: 0 articles | PPR: PPR869208
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Decreased eukaryotic initiation factors expression upon temozolomide treatment-potential novel implications for eIFs in glioma therapy.
Krassnig S, Leber SL, Orthmann A, Golob-Schwarzl N, Huber HJ, Wohlrab C, Skofler C, Pennauer M, Raicht A, Birkl-Toeglhofer AM, Naumann M, Mahdy-Ali K, von Campe G, Leoni M, Alcaniz J, Hoffmann J, Wälchli T, Weis S, Benesch M, Haybaeck J
J Neurooncol, 165(1):91-100, 31 Oct 2023
Cited by: 0 articles | PMID: 37907716 | PMCID: PMC10638187
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Radius additivity score: a novel combination index for tumour growth inhibition in fixed-dose xenograft studies.
Melillo N, Dickinson J, Tan L, Mistry HB, Huber HJ
Front Pharmacol, 14:1272058, 13 Oct 2023
Cited by: 0 articles | PMID: 37900154 | PMCID: PMC10603293
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Transcriptomic and Proteomic Changes Driving Pulmonary Fibrosis Resolution in Young and Old Mice.
Weckerle J, Mayr CH, Fundel-Clemens K, Lämmle B, Boryn L, Thomas MJ, Bretschneider T, Luippold AH, Huber HJ, Viollet C, Rist W, Veyel D, Ramirez F, Klee S, Kästle M
Am J Respir Cell Mol Biol, 69(4):422-440, 01 Oct 2023
Cited by: 3 articles | PMID: 37411041
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Explaining in-vitro to in-vivo efficacy correlations in oncology pre-clinical development via a semi-mechanistic mathematical model.
Huber HJ, Mistry HB
J Pharmacokinet Pharmacodyn, 51(2):169-185, 06 Nov 2023
Cited by: 0 articles | PMID: 37930506 | PMCID: PMC10982099
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Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen-specific tumor cell killing by cytotoxic T cells.
Herzfeldt AK, Gamez MP, Martin E, Boryn LM, Baskaran P, Huber HJ, Schuler M, Park JE, Swee LK
Elife, 12:e84314, 21 Sep 2023
Cited by: 0 articles | PMID: 37732732 | PMCID: PMC10586807
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Antifibrotic Drug Nintedanib Inhibits CSF1R to Promote IL-4-associated Tissue Repair Macrophages.
Watson CK, Schloesser D, Fundel-Clemens K, Lerner C, Gabler S, Baskaran P, Wohnhaas CT, Dichtl S, Huber HJ, Ask K, Gantner F, Viollet C, Thomas MJ, Ramirez F, Murray PJ, El Kasmi KC
Am J Respir Cell Mol Biol, 68(4):366-380, 01 Apr 2023
Cited by: 5 articles | PMID: 36227799
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Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen specific tumor cell killing by cytotoxic T cells
Mattes A, Gamez MP, Martin E, Boryn L, Baskaran P, Huber HJ, Schuler M, Park JE, Swee LK
bioRxiv, 27 Aug 2022
Cited by: 0 articles | PPR: PPR537041
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A method for the identification of COVID-19 biomarkers in human breath using Proton Transfer Reaction Time-of-Flight Mass Spectrometry.
Liangou A, Tasoglou A, Huber HJ, Wistrom C, Brody K, Menon PG, Bebekoski T, Menschel K, Davidson-Fiedler M, DeMarco K, Salphale H, Wistrom J, Wistrom S, Lee RJ
EClinicalMedicine, 42:101207, 20 Nov 2021
Cited by: 15 articles | PMID: 34841237 | PMCID: PMC8604657
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Graft-Versus-Host Disease Prevention by In Vitro-Generated Myeloid-Derived Suppressor Cells Is Exclusively Mediated by the CD11b+CD11c+ MDSC Subpopulation.
Scheurer J, Kitt K, Huber HJ, Fundel-Clemens K, Pflanz S, Debatin KM, Strauss G
Front Immunol, 12:754316, 14 Oct 2021
Cited by: 2 articles | PMID: 34721430 | PMCID: PMC8551363
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CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1.
Durlanik S, Fundel-Clemens K, Viollet C, Huber HJ, Lenter M, Kitt K, Pflanz S
Sci Rep, 11(1):14849, 21 Jul 2021
Cited by: 10 articles | PMID: 34290311 | PMCID: PMC8295264
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High-Yield Human Induced Pluripotent Stem Cell-Derived Monocytes and Macrophages Are Functionally Comparable With Primary Cells.
Cui D, Franz A, Fillon SA, Jannetti L, Isambert T, Fundel-Clemens K, Huber HJ, Viollet C, Ghanem A, Niwa A, Weigle B, Pflanz S
Front Cell Dev Biol, 9:656867, 13 Apr 2021
Cited by: 11 articles | PMID: 33937256 | PMCID: PMC8080307
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Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling.
Reeh H, Rudolph N, Billing U, Christen H, Streif S, Bullinger E, Schliemann-Bullinger M, Findeisen R, Schaper F, Huber HJ, Dittrich A
Cell Commun Signal, 17(1):46, 17 May 2019
Cited by: 66 articles | PMID: 31101051 | PMCID: PMC6525395
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Quantitative proteomics and systems analysis of cultured H9C2 cardiomyoblasts during differentiation over time supports a 'function follows form' model of differentiation.
Kankeu C, Clarke K, Van Haver D, Gevaert K, Impens F, Dittrich A, Roderick HL, Passante E, Huber HJ
Mol Omics, 14(3):181-196, 01 Jun 2018
Cited by: 6 articles | PMID: 29770421
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Sub-femtomolar detection of DNA and discrimination of mutant strands using microwell-array assisted digital enzyme-linked oligonucleotide assay.
Tripodi L, Witters D, Kokalj T, Huber HJ, Puers R, Lammertyn J, Spasic D
Anal Chim Acta, 1041:122-130, 30 Aug 2018
Cited by: 2 articles | PMID: 30340684
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Expression profile of translation initiation factor eIF2B5 in diffuse large B-cell lymphoma and its correlation to clinical outcome.
Unterluggauer JJ, Prochazka K, Tomazic PV, Huber HJ, Seeboeck R, Fechter K, Steinbauer E, Gruber V, Feichtinger J, Pichler M, Weniger MA, Küppers R, Sill H, Schicho R, Neumeister P, Beham-Schmid C, Deutsch AJA, Haybaeck J
Blood Cancer J, 8(9):79, 22 Aug 2018
Cited by: 3 articles | PMID: 30190479 | PMCID: PMC6127263
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The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling.
Baran P, Hansen S, Waetzig GH, Akbarzadeh M, Lamertz L, Huber HJ, Ahmadian MR, Moll JM, Scheller J
J Biol Chem, 293(18):6762-6775, 20 Mar 2018
Cited by: 104 articles | PMID: 29559558 | PMCID: PMC5936821
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Stable IL- 1β-Activation in an Inflammasome Signalling Model Depends on Positive and Negative Feedbacks and Tight Regulation of Protein Production.
Lopez-Caamal F, Huber HJ
IEEE/ACM Trans Comput Biol Bioinform, 16(2):627-637, 18 Jan 2018
Cited by: 0 articles | PMID: 29994183
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Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform.
Anilkumar U, Weisova P, Schmid J, Bernas T, Huber HJ, Düssmann H, Connolly NMC, Prehn JHM
PLoS One, 12(11):e0188343, 16 Nov 2017
Cited by: 5 articles | PMID: 29145487 | PMCID: PMC5690623
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Identifying differential miR and gene consensus patterns in peripheral blood of patients with cardiovascular diseases from literature data.
Šatrauskienė A, Navickas R, Laucevičius A, Huber HJ
BMC Cardiovasc Disord, 17(1):173, 30 Jun 2017
Cited by: 3 articles | PMID: 28666417 | PMCID: PMC5493858
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Doxorubicin-induced chronic dilated cardiomyopathy-the apoptosis hypothesis revisited.
Kankeu C, Clarke K, Passante E, Huber HJ
J Mol Med (Berl), 95(3):239-248, 08 Dec 2016
Cited by: 21 articles | PMID: 27933370
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Signal transduction analysis of the NLRP3-inflammasome pathway after cellular damage and its paracrine regulation.
Veltman D, Laeremans T, Passante E, Huber HJ
J Theor Biol, 415:125-136, 22 Dec 2016
Cited by: 7 articles | PMID: 28017802
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Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical Reactions.
Connolly NM, D'Orsi B, Monsefi N, Huber HJ, Prehn JH
PLoS One, 11(2):e0148326, 03 Feb 2016
Cited by: 3 articles | PMID: 26840769 | PMCID: PMC4740490
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Modelling tumour cell proliferation from vascular structure using tissue decomposition into avascular elements.
Besenhard MO, Jarzabek M, O'Farrell AC, Callanan JJ, Prehn JH, Byrne AT, Huber HJ
J Theor Biol, 402:129-143, 05 May 2016
Cited by: 2 articles | PMID: 27155046
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1-25 of 65 results

1 2 3

Search life-sciences literature (45,104,206 articles, preprints and more)

Search results

Individual Patient Data Analysis of Liver Lesion Dynamics: A Pan Cancer Analysis

In Silico Treatment: a computational framework for animal model selection and drug assessment

Decreased eukaryotic initiation factors expression upon temozolomide treatment-potential novel implications for eIFs in glioma therapy.

Radius additivity score: a novel combination index for tumour growth inhibition in fixed-dose xenograft studies.

Transcriptomic and Proteomic Changes Driving Pulmonary Fibrosis Resolution in Young and Old Mice.

Explaining in-vitro to in-vivo efficacy correlations in oncology pre-clinical development via a semi-mechanistic mathematical model.

Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen-specific tumor cell killing by cytotoxic T cells.

Antifibrotic Drug Nintedanib Inhibits CSF1R to Promote IL-4-associated Tissue Repair Macrophages.

Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen specific tumor cell killing by cytotoxic T cells

A method for the identification of COVID-19 biomarkers in human breath using Proton Transfer Reaction Time-of-Flight Mass Spectrometry.

Graft-Versus-Host Disease Prevention by In Vitro-Generated Myeloid-Derived Suppressor Cells Is Exclusively Mediated by the CD11b+CD11c+ MDSC Subpopulation.

CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1.

High-Yield Human Induced Pluripotent Stem Cell-Derived Monocytes and Macrophages Are Functionally Comparable With Primary Cells.

Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling.

Quantitative proteomics and systems analysis of cultured H9C2 cardiomyoblasts during differentiation over time supports a 'function follows form' model of differentiation.

Sub-femtomolar detection of DNA and discrimination of mutant strands using microwell-array assisted digital enzyme-linked oligonucleotide assay.

Expression profile of translation initiation factor eIF2B5 in diffuse large B-cell lymphoma and its correlation to clinical outcome.

The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling.

Stable IL- 1β-Activation in an Inflammasome Signalling Model Depends on Positive and Negative Feedbacks and Tight Regulation of Protein Production.

Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform.

Identifying differential miR and gene consensus patterns in peripheral blood of patients with cardiovascular diseases from literature data.

Doxorubicin-induced chronic dilated cardiomyopathy-the apoptosis hypothesis revisited.

Signal transduction analysis of the NLRP3-inflammasome pathway after cellular damage and its paracrine regulation.

Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical Reactions.

Modelling tumour cell proliferation from vascular structure using tissue decomposition into avascular elements.

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