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Search life-sciences literature (45,100,050 articles, preprints and more)

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An Open Letter to the Food and Drug Administration and Pharmaceutical Industry Concerning Drug Approval for Children With Inflammatory Bowel Disease.
Hyams JS, Winter HS, Mulberg AE, Zuckerman E
Inflamm Bowel Dis, izae226, 08 Oct 2024
Cited by: 0 articles | PMID: 39377256
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Partnering With School Nurses for Continuing Education in Inflammatory Bowel Disease.
Marrero J, Jerson B, Brimacombe M, Hopkins D, Hinderer KA, Hyams JS
J Contin Educ Nurs, 1-7, 02 Oct 2024
Cited by: 0 articles | PMID: 39361537
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Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have a Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn's Disease.
Olivera PA, Martinez-Lozano H, Leibovitzh H, Xue M, Neustaeter A, Espin-Garcia O, Xu W, Madsen KL, Guttman DS, Bernstein CN, Yerushalmi B, Hyams JS, Abreu MT, Marshall JK, Wrobel I, Mack DR, Jacobson K, Bitton A, Aumais G, [...] Microbial (GEM) Project Research Consortium
Gastroenterology, S0016-5085(24)05414-3, 03 Sep 2024
Cited by: 0 articles | PMID: 39236898
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Outcomes in Adult Inflammatory Bowel Disease Clinical Trials: Assessment of Similarity Among Participants with Adolescent-onset and Adult-onset Disease.
Rosh JR, Turner D, Hyams JS, Dubinsky M, Griffiths AM, Cohen SA, Hung Lo K, Kim L, Volger S, Zhang R, Strauss R, Conklin LS
J Crohns Colitis, 18(8):1250-1260, 01 Aug 2024
Cited by: 0 articles | PMID: 38408273
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Ustekinumab in paediatric patients with moderately to severely active Crohn's disease: UniStar study long-term extension results.
Turner D, Rosh JR, Cohen SA, Griffiths AM, Hyams JS, Kierkuś J, Adedokun OJ, Strauss R, Kim L, Volger S, UniStar Study Group
J Pediatr Gastroenterol Nutr, 79(2):315-324, 27 May 2024
Cited by: 0 articles | PMID: 38801079
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Identification of Arginine-Vasopressin Receptor 1a (Avpr1a/Avpr1a) as a Novel Candidate Gene for Chronic Visceral Pain Sheds Light on the Potential Role of Enteric Neurons in the Development of Visceral Hypersensitivity.
Kader L, Willits AB, Meriano S, Christianson JA, La JH, Feng B, Knight B, Kosova G, Deberry JJ, Coates MD, Hyams JS, Baumbauer KM, Young EE
J Pain, 25(9):104572, 18 May 2024
Cited by: 1 article | PMID: 38768798
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Environmental Factors Associated With Risk of Crohn's Disease Development in the Crohn's and Colitis Canada - Genetic, Environmental, Microbial Project.
Xue M, Leibovitzh H, Jingcheng S, Neustaeter A, Dong M, Xu W, Espin-Garcia O, Griffiths AM, Steinhart AH, Turner D, Huynh HQ, Dieleman LA, Panaccione R, Aumais G, Bressler B, Bitton A, Murthy S, Marshall JK, Hyams JS, [...] Croitoru K
Clin Gastroenterol Hepatol, 22(9):1889-1897.e12, 16 May 2024
Cited by: 0 articles | PMID: 38759825
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Randomized controlled trial of linaclotide in children aged 6-17 years with functional constipation.
Di Lorenzo C, Nurko S, Hyams JS, Rodriguez-Araujo G, Almansa C, Shakhnovich V, Saps M, Simon M
J Pediatr Gastroenterol Nutr, 78(5):1059-1068, 27 Mar 2024
Cited by: 0 articles | PMID: 38533633
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Fitness-for-use of Retrospective Multicenter Electronic Health Records to Conduct Outcome Analysis for Pediatric Ulcerative Colitis.
Wang Z, Song X, Waitman LR, Hyams JS, Denson LA
Medicine (Baltimore), 103(11):e37395, 01 Mar 2024
Cited by: 0 articles | PMID: 38489703 | PMCID: PMC10939680
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A comparison of Bayesian and frequentist approaches to incorporating clinical and biological information for the prediction of response to standardized pediatric colitis therapy.
Wang Z, Nie J, Song X, Denson LA, Hyams JS
PLoS One, 19(3):e0295814, 06 Mar 2024
Cited by: 0 articles | PMID: 38446811
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Recommendations for Standardizing MRI-based Evaluation of Perianal Fistulizing Disease Activity in Pediatric Crohn's Disease Clinical Trials.
Crowley E, Ma C, Guizzetti L, Zou G, Lewindon PJ, Gee MS, Hyams JS, Rosen MJ, von Allmen D, de Buck van Overstraeten A, Shackelton LM, Remillard J, Schleicher L, Dillman JR, Rimola J, Taylor SA, Fletcher JG, Church PC, Feagan BG, [...] Greer MC
Inflamm Bowel Dis, 30(3):357-369, 01 Mar 2024
Cited by: 1 article | PMID: 37524088
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Machine Learning-Based Prediction of Pediatric Ulcerative Colitis Treatment Response Using Diagnostic Histopathology.
Liu X, Prasath S, Siddiqui I, Walters TD, Denson LA, PROTECT Consortium, Dhaliwal J
Gastroenterology, 166(5):921-924.e4, 02 Feb 2024
Cited by: 4 articles | PMID: 38309631
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Efficacy and safety of linaclotide in treating functional constipation in paediatric patients: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial.
Di Lorenzo C, Khlevner J, Rodriguez-Araujo G, Xie W, Huh SY, Ando M, Hyams JS, Nurko S, Benninga MA, Simon M, Hewson ME, Saps M
Lancet Gastroenterol Hepatol, 9(3):238-250, 08 Jan 2024
Cited by: 1 article | PMID: 38211604
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Safety and efficacy of linaclotide in children aged 7-17 years with irritable bowel syndrome with constipation.
Di Lorenzo C, Nurko S, Hyams JS, Rodriguez-Araujo G, Shakhnovich V, Saps M, Simon M
J Pediatr Gastroenterol Nutr, 78(3):539-547, 28 Dec 2023
Cited by: 1 article | PMID: 38504394
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Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization.
Geem D, Hercules D, Pelia RS, Venkateswaran S, Griffiths A, Noe JD, Dotson JL, Snapper S, Rabizadeh S, Rosh JR, Baldassano RN, Markowitz JF, Walters TD, Ananthakrishnan A, Sharma G, Denson LA, Hyams JS, Kugathasan S
Clin Gastroenterol Hepatol, 22(2):368-376.e4, 05 Oct 2023
Cited by: 1 article | PMID: 37802268
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Managing pediatric Crohn's disease: recent insights.
Baldwin K, Grossi V, Hyams JS
Expert Rev Gastroenterol Hepatol, 17(10):949-958, 01 Jul 2023
Cited by: 0 articles | PMID: 37794692
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Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease.
Braun T, Sosnovski KE, Amir A, BenShoshan M, VanDussen KL, Karns R, Levhar N, Abbas-Egbariya H, Hadar R, Efroni G, Castel D, Avivi C, Rosen MJ, Grifiths AM, Walters TD, Mack DR, Boyle BM, Ali SA, Moore SR, [...] Haberman Y
JCI Insight, 8(14):e170181, 24 Jul 2023
Cited by: 7 articles | PMID: 37261910 | PMCID: PMC10443795
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The State of Clinical Trials in Pediatric Inflammatory Bowel Disease.
Hyams JS, Russell RK
Gastroenterol Clin North Am, 52(3):589-597, 20 Jun 2023
Cited by: 0 articles | PMID: 37543402
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GATA6-AS1 Regulates Intestinal Epithelial Mitochondrial Functions, and its Reduced Expression is Linked to Intestinal Inflammation and Less Favourable Disease Course in Ulcerative Colitis.
Sosnovski KE, Braun T, Amir A, Moshel D, BenShoshan M, VanDussen KL, Levhar N, Abbas-Egbariya H, Beider K, Ben-Yishay R, Asad Ali S, Moore SR, Kugathasan S, Abramovich I, Glick Saar E, Weiss B, Barshack I, Gottlieb E, Geiger T, [...] Haberman Y
J Crohns Colitis, 17(6):960-971, 01 Jun 2023
Cited by: 10 articles | PMID: 36655602 | PMCID: PMC10274303
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Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.
Raygoza Garay JA, Turpin W, Lee SH, Smith MI, Goethel A, Griffiths AM, Moayyedi P, Espin-Garcia O, Abreu M, Aumais GL, Bernstein CN, Biron IA, Cino M, Deslandres C, Dotan I, El-Matary W, Feagan B, Guttman DS, Huynh H, [...] Croitoru K
Gastroenterology, 165(3):670-681, 30 May 2023
Cited by: 30 articles | PMID: 37263307
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Paediatric Inflammatory Bowel Disease: A Multi-Stakeholder Perspective to Improve Development of Drugs for Children and Adolescents.
Croft NM, de Ridder L, Griffiths AM, Hyams JS, Ruemmele FM, Turner D, Cheng K, Lutsar I, Greco M, Gołębiewska Z, Laumond F, Cavaller-Bellaubi M, Elgreey A, Altepeter TA, Pallidis C, Norga K, Nelson R, Crandall W, Vassal G
J Crohns Colitis, 17(2):249-258, 01 Mar 2023
Cited by: 2 articles | PMID: 36130314 | PMCID: PMC10024546
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Longitudinal DNA methylation profiling of the rectal mucosa identifies cell-specific signatures of disease status, severity and clinical outcomes in ulcerative colitis cell-specific DNA methylation signatures of UC.
Venkateswaran S, Somineni HK, Matthews JD, Kilaru V, Hyams JS, Denson LA, Kellamayer R, Gibson G, Cutler DJ, Conneely KN, Smith AK, Kugathasan S
Clin Epigenetics, 15(1):50, 24 Mar 2023
Cited by: 3 articles | PMID: 36964596 | PMCID: PMC10039532
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Development and Validation of the TUMMY-UC: A Patient-Reported Outcome for Pediatric Ulcerative Colitis.
Marcovitch L, Focht G, Carmon N, Tersigni C, Ledder O, Lev-Tzion R, Church PC, Hyams JS, Baldassano RN, Bousvaros A, Mack DR, Hussey S, Otley A, Croft NM, Kappelman MD, Griffiths AM, Turner D
Gastroenterology, 164(4):610-618.e4, 17 Dec 2022
Cited by: 2 articles | PMID: 36539016
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Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis.
Clarkston K, Karns R, Jegga AG, Sharma M, Fox S, Ojo BA, Minar P, Walters TD, Griffiths AM, Mack DR, Boyle B, LeLeiko NS, Markowitz J, Rosh JR, Patel AS, Shah S, Baldassano RN, Pfefferkorn M, Sauer C, [...] Rosen MJ
J Crohns Colitis, 16(11):1735-1750, 01 Nov 2022
Cited by: 2 articles | PMID: 35665804 | PMCID: PMC9683081
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Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedolizumab clearance.
Colman RJ, Mizuno T, Fukushima K, Haslam DB, Hyams JS, Boyle B, Noe JD, D'Haens GR, Van Limbergen J, Chun K, Yang J, Denson LA, Ollberding NJ, Vinks AA, Minar P
Aliment Pharmacol Ther, 57(5):524-539, 31 Oct 2022
Cited by: 6 articles | PMID: 36314265 | PMCID: PMC9931651
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