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Search life-sciences literature (45,103,589 articles, preprints and more)

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The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis.
Smeets MF, DeLuca E, Wall M, Quach JM, Chalk AM, Deans AJ, Heierhorst J, Purton LE, Izon DJ, Walkley CR
J Clin Invest, 124(8):3551-3565, 24 Jun 2014
Cited by: 25 articles | PMID: 24960165 | PMCID: PMC4109528
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Fli-1 regulates the DN2 to DN3 thymocyte transition and promotes γδ T-cell commitment by enhancing TCR signal strength.
Smeets MF, Wiest DL, Izon DJ
Eur J Immunol, 44(9):2617-2624, 24 Jul 2014
Cited by: 6 articles | PMID: 24935715 | PMCID: PMC5242326
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Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma.
Smeets MF, Chan AC, Dagger S, Bradley CK, Wei A, Izon DJ
PLoS One, 8(5):e62346, 07 May 2013
Cited by: 18 articles | PMID: 23667468 | PMCID: PMC3646842
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This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
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Removal of myeloid cytokines from the cellular environment enhances T-cell development in vitro.
Smeets MF, Mackenzie-Kludas C, Mohtashami M, Zhang HH, Zúñiga-Pflücker JC, Izon DJ
Int Immunol, 25(10):589-599, 29 Aug 2013
Cited by: 2 articles | PMID: 23988615
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The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim.
Jurado S, Gleeson K, O'Donnell K, Izon DJ, Walkley CR, Strasser A, Tarlinton DM, Heierhorst J
J Exp Med, 209(9):1629-1639, 13 Aug 2012
Cited by: 33 articles | PMID: 22891272 | PMCID: PMC3428950
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Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia.
Glaser SP, Lee EF, Trounson E, Bouillet P, Wei A, Fairlie WD, Izon DJ, Zuber J, Rappaport AR, Herold MJ, Alexander WS, Lowe SW, Robb L, Strasser A
Genes Dev, 26(2):120-125, 01 Jan 2012
Cited by: 248 articles | PMID: 22279045 | PMCID: PMC3273836
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Taking HSCs down a Notch in leukemia.
Walkley CR, Izon DJ, Purton LE
Cell Stem Cell, 8(6):602-603, 01 Jun 2011
Cited by: 1 article | PMID: 21624800
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Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment.
Singbrant S, Russell MR, Jovic T, Liddicoat B, Izon DJ, Purton LE, Sims NA, Martin TJ, Sankaran VG, Walkley CR
Blood, 117(21):5631-5642, 18 Mar 2011
Cited by: 95 articles | PMID: 21421837
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Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms.
Oliaro J, Van Ham V, Sacirbegovic F, Pasam A, Bomzon Z, Pham K, Ludford-Menting MJ, Waterhouse NJ, Bots M, Hawkins ED, Watt SV, Cluse LA, Clarke CJ, Izon DJ, Chang JT, Thompson N, Gu M, Johnstone RW, Smyth MJ, [...] Russell SM
J Immunol, 185(1):367-375, 07 Jun 2010
Cited by: 79 articles | PMID: 20530266 | PMCID: PMC3739982
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T-cell development: thymus-settling progenitors: settled?
Izon DJ
Immunol Cell Biol, 86(7):552-553, 29 Jul 2008
Cited by: 5 articles | PMID: 18663375
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Overexpression of stem cell associated ALDH1A1, a target of the leukemogenic transcription factor TLX1/HOX11, inhibits lymphopoiesis and promotes myelopoiesis in murine hematopoietic progenitors.
Rice KL, Izon DJ, Ford J, Boodhoo A, Kees UR, Greene WK
Leuk Res, 32(6):873-883, 21 Dec 2007
Cited by: 19 articles | PMID: 18082256
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An in vivo functional genetic screen for suppressors of the Rag1-/- T-cell defect.
Chan AC, Smeets MF, Izon DJ
Mol Immunol, 45(3):682-689, 10 Sep 2007
Cited by: 0 articles | PMID: 17826832
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NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis.
Göthert JR, Brake RL, Smeets M, Dührsen U, Begley CG, Izon DJ
Blood, 110(10):3753-3762, 13 Aug 2007
Cited by: 23 articles | PMID: 17698635
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Perturbed thymopoiesis in vitro in the absence of suppressor of cytokine signalling 1 and 3.
Croom HA, Izon DJ, Chong MM, Curtis DJ, Roberts AW, Kay TW, Hilton DJ, Alexander WS, Starr R
Mol Immunol, 45(10):2888-2896, 05 Mar 2008
Cited by: 9 articles | PMID: 18321577 | PMCID: PMC4291229
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TLX1/HOX11 transcription factor inhibits differentiation and promotes a non-haemopoietic phenotype in murine bone marrow cells.
Dixon DN, Izon DJ, Dagger S, Callow MJ, Taplin RH, Kees UR, Greene WK
Br J Haematol, 138(1):54-67, 01 Jul 2007
Cited by: 12 articles | PMID: 17555447
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Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals.
Michie AM, Chan AC, Ciofani M, Carleton M, Lefebvre JM, He Y, Allman DM, Wiest DL, Zúñiga-Pflücker JC, Izon DJ
Int Immunol, 19(12):1421-1430, 01 Nov 2007
Cited by: 22 articles | PMID: 17981791
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Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia.
Glaser S, Metcalf D, Wu L, Hart AH, DiRago L, Mifsud S, D'Amico A, Dagger S, Campo C, Chan AC, Izon DJ, Robb L
Proc Natl Acad Sci U S A, 103(44):16460-16465, 23 Oct 2006
Cited by: 8 articles | PMID: 17060613 | PMCID: PMC1637604
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In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis.
Göthert JR, Gustin SE, Hall MA, Green AR, Göttgens B, Izon DJ, Begley CG
Blood, 105(7):2724-2732, 14 Dec 2004
Cited by: 114 articles | PMID: 15598809
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Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium.
Göthert JR, Gustin SE, van Eekelen JA, Schmidt U, Hall MA, Jane SM, Green AR, Göttgens B, Izon DJ, Begley CG
Blood, 104(6):1769-1777, 08 Jun 2004
Cited by: 190 articles | PMID: 15187022
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An invitation to T and more: notch signaling in lymphopoiesis.
Allman D, Punt JA, Izon DJ, Aster JC, Pear WS
Cell, 109 Suppl:S1-11, 01 Apr 2002
Cited by: 71 articles | PMID: 11983148
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Serial analysis of gene expression in murine fetal thymocyte cell lines.
Zhao FQ, Sheng ZM, Tsai MM, Hubbs AE, Wang R, O'Leary TJ, Izon DJ, Taubenberger JK
Int Immunol, 14(12):1383-1395, 01 Dec 2002
Cited by: 7 articles | PMID: 12456586
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Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1.
Izon DJ, Aster JC, He Y, Weng A, Karnell FG, Patriub V, Xu L, Bakkour S, Rodriguez C, Allman D, Pear WS
Immunity, 16(2):231-243, 01 Feb 2002
Cited by: 162 articles | PMID: 11869684
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Deciphering the role of Notch signaling in lymphopoiesis.
Izon DJ, Punt JA, Pear WS
Curr Opin Immunol, 14(2):192-199, 01 Apr 2002
Cited by: 33 articles | PMID: 11869892
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Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength.
Izon DJ, Punt JA, Xu L, Karnell FG, Allman D, Myung PS, Boerth NJ, Pui JC, Koretzky GA, Pear WS
Immunity, 14(3):253-264, 01 Mar 2001
Cited by: 122 articles | PMID: 11290335
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The COX-2 inhibitor NS-398 causes T-cell developmental disruptions independent of COX-2 enzyme inhibition.
Xu H, Izon DJ, Loftin C, Spain LM
Cell Immunol, 214(2):184-193, 01 Dec 2001
Cited by: 9 articles | PMID: 12088417
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