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Search life-sciences literature (45,100,050 articles, preprints and more)

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Acute increase of protein O-GlcNAcylation in mice leads to transcriptome changes in the brain opposite to what is observed in Alzheimer’s Disease
Bell M, Kane MS, Ouyang X, Young ME, Jegga AG, Chatham JC, Darley-Usmar V, Zhang J
bioRxiv, 20 Sep 2024
Cited by: 0 articles | PPR: PPR913064
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The protein disulfide isomerase A3 and osteopontin axis promotes influenza-induced lung remodelling.
Kumar A, Mark ZF, Carbajal MP, DeLima DS, Chamberlain N, Walzer J, Ruban M, Chandrasekaran R, Daphtary N, Aliyeva M, Poynter ME, Janssen-Heininger YMW, Bates JH, Alcorn JF, Britto CJ, Dela Cruz CS, Jegga AG, Anathy V
Br J Pharmacol, 181(22):4610-4627, 08 Aug 2024
Cited by: 0 articles | PMID: 39118388
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Specific binding sites on Rhesus rotavirus capsid protein dictate the method of endocytosis inducing the murine model of biliary atresia.
Temple H, Donnelly B, Mohanty SK, Mowery S, Poling HM, Pasula R, Hartman S, Singh A, Mourya R, Bondoc A, Meller J, Jegga AG, Oyama K, McNeal M, Spearman P, Tiao G
Am J Physiol Gastrointest Liver Physiol, 327(2):G267-G283, 11 Jun 2024
Cited by: 0 articles | PMID: 38860860
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Roles of cMyBP-C phosphorylation on cardiac contractile dysfunction in db/db mice.
Desai DA, Baby A, Ananthamohan K, Green LC, Arif M, Duncan BC, Kumar M, Singh RR, Koch SE, Natesan S, Rubinstein J, Jegga AG, Sadayappan S
J Mol Cell Cardiol Plus, 8:100075, 04 Apr 2024
Cited by: 0 articles | PMID: 38957358 | PMCID: PMC11218625
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Contribution of leukocyte telomere length to major cardiovascular diseases onset: phenotypic and genetic insights from a large-scale genome-wide cross-trait analysis
Qiao J, Wang Q, Zhao Y, Chang M, Cai L, Liu F, Yao K, Zheng L, Tan N, He P, Jegga AG, Pauklin S, Jiang L, Yang Y, Feng Y
medRxiv, 22 May 2024
Cited by: 0 articles | PPR: PPR856282
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SEMA3B inhibits TGFβ-induced extracellular matrix protein production and its reduced levels are associated with a decline in lung function in IPF.
Yombo DJK, Ghandikota S, Vemulapalli CP, Singh P, Jegga AG, Hardie WD, Madala SK
Am J Physiol Cell Physiol, 326(6):C1659-C1668, 22 Apr 2024
Cited by: 1 article | PMID: 38646784 | PMCID: PMC11371361
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Application of artificial intelligence and machine learning in drug repurposing.
Ghandikota SK, Jegga AG
Prog Mol Biol Transl Sci, 205:171-211, 31 Mar 2024
Cited by: 0 articles | PMID: 38789178
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Neuroinflammation underlies the development of social stress induced cognitive deficit in sickle cell disease
DeVeaux SA, Vyshnya S, Propsom K, Gbotosho OT, Singh AS, Horning RZ, Sharma M, Jegga AG, Niu L, Botchwey EA, Hyacinth HI
bioRxiv, 25 Jan 2024
Cited by: 0 articles | PPR: PPR793245
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Endothelial cells differentiated from patient dermal fibroblast-derived induced pluripotent stem cells resemble vascular malformations of port-wine birthmark.
Nguyen V, Gao C, Hochman ML, Kravitz J, Chen EH, Friedman HI, Wenceslau CF, Chen D, Wang Y, Nelson JS, Jegga AG, Tan W
Br J Dermatol, 189(6):780-783, 01 Nov 2023
Cited by: 2 articles | PMID: 37672656 | PMCID: PMC10653332
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Perturbations of Glutathione and Sphingosine Metabolites in Port Wine Birthmark Patient-Derived Induced Pluripotent Stem Cells.
Nguyen V, Kravitz J, Gao C, Hochman ML, Meng D, Chen D, Wang Y, Jegga AG, Nelson JS, Tan W
Metabolites, 13(9):983, 31 Aug 2023
Cited by: 0 articles | PMID: 37755263 | PMCID: PMC10537749
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BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma.
Feng Y, Cai L, Pook M, Liu F, Chang CH, Mouti MA, Nibhani R, Militi S, Dunford J, Philpott M, Fan Y, Fan GC, Liu Q, Qi J, Wang C, Hong W, Morgan H, Wang M, Sadayappan S, [...] Pauklin S
Gastroenterology, 166(1):139-154, 21 Sep 2023
Cited by: 3 articles | PMID: 37739089 | PMCID: PMC11304550
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Perturbations of glutathione and sphingosine metabolites in Port Wine Birthmark patient-derived induced pluripotent stem cells
Nguyen V, Kravitz J, Gao C, Hochman ML, Meng D, Chen D, Wang Y, Jegga AG, Nelson JS, Tan W
bioRxiv, 19 Jul 2023
Cited by: 0 articles | PPR: PPR694028
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Relationships between gene expression and behavior in mice in response to systemic modulation of the O-GlcNAcylation pathway.
Bell MB, Ouyang X, Shelton AK, Huynh NV, Mueller T, Chacko BK, Jegga AG, Chatham JC, Miller CR, Darley-Usmar V, Zhang J
J Neurochem, 165(5):682-700, 13 May 2023
Cited by: 1 article | PMID: 37129420
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Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease.
Braun T, Sosnovski KE, Amir A, BenShoshan M, VanDussen KL, Karns R, Levhar N, Abbas-Egbariya H, Hadar R, Efroni G, Castel D, Avivi C, Rosen MJ, Grifiths AM, Walters TD, Mack DR, Boyle BM, Ali SA, Moore SR, [...] Haberman Y
JCI Insight, 8(14):e170181, 24 Jul 2023
Cited by: 7 articles | PMID: 37261910 | PMCID: PMC10443795
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Supporting materials: Endothelial cells differentiated from patient dermal fibroblast-derived induced pluripotent stem cells resemble vascular malformations of Port Wine Birthmark
Nguyen V, Gao C, Hochman ML, Kravitz J, Chen EH, Friedman HI, Wenceslau CF, Chen D, Wang Y, Nelson JS, Jegga AG, Tan W
bioRxiv, 02 Jul 2023
Cited by: 0 articles | PPR: PPR685503
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Transcriptome analysis in acute gastrointestinal graft-versus host disease reveals a unique signature in children and shared biology with pediatric inflammatory bowel disease.
Khandelwal P, Lounder DT, Bartlett A, Haberman Y, Jegga AG, Ghandikota S, Koo J, Luebbering N, Leino D, Abdullah S, Loveless M, Minar P, Lake K, Litts B, Karns R, Nelson AS, Denson LA, Davies SM
Haematologica, 108(7):1803-1816, 01 Jul 2023
Cited by: 1 article | PMID: 36727399
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A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases.
Zeighami Y, Bakken TE, Nickl-Jockschat T, Peterson Z, Jegga AG, Miller JA, Schulkin J, Evans AC, Lein ES, Hawrylycz M
PLoS Biol, 21(4):e3002058, 20 Apr 2023
Cited by: 11 articles | PMID: 37079537 | PMCID: PMC10118126
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A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis.
Tsai CY, Saito T, Sarangdhar M, Abu-El-Haija M, Wen L, Lee B, Yu M, Lipata DA, Manohar M, Barakat MT, Contrepois K, Tran TH, Theoret Y, Bo N, Ding Y, Stevenson K, Ladas EJ, Silverman LB, Quadro L, [...] Husain SZ
Sci Transl Med, 15(687):eabn2110, 15 Mar 2023
Cited by: 3 articles | PMID: 36921036 | PMCID: PMC10205044
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BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma
Feng Y, Cai L, Pook M, Liu F, Chang C, Mouti MA, Nibhani R, Wu S, Deng S, Militi S, Dunford J, Philpott M, Fan Y, Fan G, Liu Q, Qi J, Sadayappan S, Jegga AG, Oppermann U, [...] Pauklin S
bioRxiv, 02 Mar 2023
Cited by: 0 articles | PPR: PPR624488
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Combination of esomeprazole and pirfenidone enhances antifibrotic efficacy in vitro and in a mouse model of TGFβ-induced lung fibrosis.
Ebrahimpour A, Ahir M, Wang M, Jegga AG, Bonnen MD, Eissa NT, Montesi SB, Raghu G, Ghebre YT
Sci Rep, 12(1):20668, 30 Nov 2022
Cited by: 3 articles | PMID: 36450789 | PMCID: PMC9712660
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Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity.
Kalim KW, Yang JQ, Wunderlich M, Modur V, Nguyen P, Li Y, Wen T, Davis AK, Verma R, Lu QR, Jegga AG, Zheng Y, Guo F
J Immunother Cancer, 10(11):e004806, 01 Nov 2022
Cited by: 6 articles | PMID: 36427906 | PMCID: PMC9703354
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Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis.
Clarkston K, Karns R, Jegga AG, Sharma M, Fox S, Ojo BA, Minar P, Walters TD, Griffiths AM, Mack DR, Boyle B, LeLeiko NS, Markowitz J, Rosh JR, Patel AS, Shah S, Baldassano RN, Pfefferkorn M, Sauer C, [...] Rosen MJ
J Crohns Colitis, 16(11):1735-1750, 01 Nov 2022
Cited by: 2 articles | PMID: 35665804 | PMCID: PMC9683081
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Personalized medicine approaches in cystic fibrosis related pancreatitis.
Mun KS, Nathan JD, Jegga AG, Wikenheiser-Brokamp KA, Abu-El-Haija M, Naren AP
Am J Transl Res, 14(10):7612-7620, 15 Oct 2022
Cited by: 0 articles | PMID: 36398272 | PMCID: PMC9641468
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GraMDTA: Multimodal Graph Neural Networks for Predicting Drug-Target Associations
Yella JK, Ghandikota SK, Jegga AG
bioRxiv, 02 Sep 2022
Cited by: 0 articles | PPR: PPR539208
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MGATRx: Discovering Drug Repositioning Candidates Using Multi-View Graph Attention.
Yella JK, Jegga AG
IEEE/ACM Trans Comput Biol Bioinform, 19(5):2596-2604, 01 Sep 2022
Cited by: 2 articles | PMID: 34014830 | PMCID: PMC10038065
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1-25 of 154 results

1 2 3 Next ...

Search life-sciences literature (45,100,050 articles, preprints and more)

Search results

Acute increase of protein O-GlcNAcylation in mice leads to transcriptome changes in the brain opposite to what is observed in Alzheimer’s Disease

The protein disulfide isomerase A3 and osteopontin axis promotes influenza-induced lung remodelling.

Specific binding sites on Rhesus rotavirus capsid protein dictate the method of endocytosis inducing the murine model of biliary atresia.

Roles of cMyBP-C phosphorylation on cardiac contractile dysfunction in db/db mice.

Contribution of leukocyte telomere length to major cardiovascular diseases onset: phenotypic and genetic insights from a large-scale genome-wide cross-trait analysis

SEMA3B inhibits TGFβ-induced extracellular matrix protein production and its reduced levels are associated with a decline in lung function in IPF.

Application of artificial intelligence and machine learning in drug repurposing.

Neuroinflammation underlies the development of social stress induced cognitive deficit in sickle cell disease

Endothelial cells differentiated from patient dermal fibroblast-derived induced pluripotent stem cells resemble vascular malformations of port-wine birthmark.

Perturbations of Glutathione and Sphingosine Metabolites in Port Wine Birthmark Patient-Derived Induced Pluripotent Stem Cells.

BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma.

Perturbations of glutathione and sphingosine metabolites in Port Wine Birthmark patient-derived induced pluripotent stem cells

Relationships between gene expression and behavior in mice in response to systemic modulation of the O-GlcNAcylation pathway.

Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease.

Supporting materials: Endothelial cells differentiated from patient dermal fibroblast-derived induced pluripotent stem cells resemble vascular malformations of Port Wine Birthmark

Transcriptome analysis in acute gastrointestinal graft-versus host disease reveals a unique signature in children and shared biology with pediatric inflammatory bowel disease.

A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases.

A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis.

BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma

Combination of esomeprazole and pirfenidone enhances antifibrotic efficacy in vitro and in a mouse model of TGFβ-induced lung fibrosis.

Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity.

Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis.

Personalized medicine approaches in cystic fibrosis related pancreatitis.

GraMDTA: Multimodal Graph Neural Networks for Predicting Drug-Target Associations

MGATRx: Discovering Drug Repositioning Candidates Using Multi-View Graph Attention.

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