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Acute Myeloid Leukemia with deletion 5q is an epigenetically distinct subgroup defined by heterozygous loss of KDM3B
Kelly K, Welte L, Sollier E, Riedel A, Browne-Burke F, Scherer M, Keer HN, Azab M, Jahn E, Doehner H, Doehner K, Lutsik P, Plass C
bioRxiv, 15 Nov 2024
Cited by: 0 articles | PPR: PPR940374
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Oral decitabine-cedazuridine versus intravenous decitabine for myelodysplastic syndromes and chronic myelomonocytic leukaemia (ASCERTAIN): a registrational, randomised, crossover, pharmacokinetics, phase 3 study.
Garcia-Manero G, McCloskey J, Griffiths EA, Yee KWL, Zeidan AM, Al-Kali A, Deeg HJ, Patel PA, Sabloff M, Keating MM, Zhu N, Gabrail NY, Fazal S, Maly J, Odenike O, Kantarjian H, DeZern AE, O'Connell CL, Roboz GJ, [...] Savona MR
Lancet Haematol, 11(1):e15-e26, 01 Jan 2024
Cited by: 4 articles | PMID: 38135371
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Guadecitabine vs TC in relapsed/refractory AML after intensive chemotherapy: a randomized phase 3 ASTRAL-2 trial.
Roboz GJ, Sanz G, Griffiths EA, Yee K, Kantarjian H, Récher C, Byrne MT, Patkowska E, Kim HJ, Thomas X, Moors I, Stock W, Illés Á, Fenaux P, Miyazaki Y, Yamauchi T, O'Connell CL, Hao Y, Keer HN, [...] Döhner H
Blood Adv, 8(8):2020-2029, 01 Apr 2024
Cited by: 1 article | PMID: 38231126 | PMCID: PMC11103175
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Correction: Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients.
Jahn E, Saadati M, Fenaux P, Gobbi M, Roboz GJ, Bullinger L, Lutsik P, Riedel A, Plass C, Jahn N, Walter C, Holzmann K, Hao Y, Naim S, Schreck N, Krzykalla J, Benner A, Keer HN, Azab M, [...] Döhner H
Leukemia, 37(11):2336-2337, 01 Nov 2023
Cited by: 0 articles | PMID: 37789148 | PMCID: PMC10624611
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Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients.
Jahn E, Saadati M, Fenaux P, Gobbi M, Roboz GJ, Bullinger L, Lutsik P, Riedel A, Plass C, Jahn N, Walter C, Holzmann K, Hao Y, Naim S, Schreck N, Krzykalla J, Benner A, Keer HN, Azab M, [...] Döhner H
Leukemia, 37(11):2187-2196, 17 Aug 2023
Cited by: 6 articles | PMID: 37591941 | PMCID: PMC10624608
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Erlotinib and Onalespib Lactate Focused on EGFR Exon 20 Insertion Non-Small Cell Lung Cancer (NSCLC): A California Cancer Consortium Phase I/II Trial (NCI 9878).
Riess JW, Reckamp KL, Frankel P, Longmate J, Kelly KA, Gandara DR, Weipert CM, Raymond VM, Keer HN, Mack PC, Newman EM, Lara PN
Clin Lung Cancer, 22(6):541-548, 15 May 2021
Cited by: 2 articles | PMID: 34140248 | PMCID: PMC9239707
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Methylomic Signatures of High Grade Serous Ovarian Cancer.
Cardenas H, Fang F, Jiang G, Perkins SM, Zhang C, Emerson RE, Hutchins G, Keer HN, Liu Y, Matei D, Nephew K
Epigenetics, 16(11):1201-1216, 08 Dec 2020
Cited by: 14 articles | PMID: 33289590 | PMCID: PMC8813084
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Guadecitabine (SGI-110) in patients with intermediate or high-risk myelodysplastic syndromes: phase 2 results from a multicentre, open-label, randomised, phase 1/2 trial.
Garcia-Manero G, Roboz G, Walsh K, Kantarjian H, Ritchie E, Kropf P, O'Connell C, Tibes R, Lunin S, Rosenblat T, Yee K, Stock W, Griffiths E, Mace J, Podoltsev N, Berdeja J, Jabbour E, Issa JJ, Hao Y, [...] Savona MR
Lancet Haematol, 6(6):e317-e327, 03 May 2019
Cited by: 36 articles | PMID: 31060979 | PMCID: PMC9012213
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Genomic and Epigenomic Signatures in Ovarian Cancer Associated with Resensitization to Platinum Drugs.
Fang F, Cardenas H, Huang H, Jiang G, Perkins SM, Zhang C, Keer HN, Liu Y, Nephew KP, Matei D
Cancer Res, 78(3):631-644, 11 Dec 2017
Cited by: 65 articles | PMID: 29229600 | PMCID: PMC5811373
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A phase I, first in human study of FP-1039 (GSK3052230), a novel FGF ligand trap, in patients with advanced solid tumors.
Tolcher AW, Papadopoulos KP, Patnaik A, Wilson K, Thayer S, Zanghi J, Gemo AT, Kavanaugh WM, Keer HN, LoRusso PM
Ann Oncol, 27(3):526-532, 08 Dec 2015
Cited by: 44 articles | PMID: 26646757
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Phase II trial of single-agent foretinib (GSK1363089) in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.
Seiwert T, Sarantopoulos J, Kallender H, McCallum S, Keer HN, Blumenschein G
Invest New Drugs, 31(2):417-424, 24 Aug 2012
Cited by: 34 articles | PMID: 22918720 | PMCID: PMC3589657
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DNA profile of nephrogenic adenoma assessed by flow cytometry.
Gaylis FD, Keer HN, Bauer KD, Kozlowski JM, Grayhack JT
Urology, 41(2):160-161, 01 Feb 1993
Cited by: 8 articles | PMID: 8497991
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Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer.
Taplin ME, Bubley GJ, Shuster TD, Frantz ME, Spooner AE, Ogata GK, Keer HN, Balk SP
N Engl J Med, 332(21):1393-1398, 01 May 1995
Cited by: 676 articles | PMID: 7723794
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Components of the plasminogen-plasmin system in human tumor cell lines.
Kwaan HC, Keer HN, Radosevich JA, Cajot JF, Ernst R
Semin Thromb Hemost, 17(3):175-182, 01 Jul 1991
Cited by: 16 articles | PMID: 1839079
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Heterogeneity in plasminogen activator (PA) levels in human prostate cancer cell lines: increased PA activity correlates with biologically aggressive behavior.
Keer HN, Gaylis FD, Kozlowski JM, Kwaan HC, Bauer KD, Sinha AA, Wilson MJ
Prostate, 18(3):201-214, 01 Jan 1991
Cited by: 37 articles | PMID: 1902292
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Plasminogen activators in human prostate cancer cell lines and tumors: correlation with the aggressive phenotype.
Gaylis FD, Keer HN, Wilson MJ, Kwaan HC, Sinha AA, Kozlowski JM
J Urol, 142(1):193-198, 01 Jul 1989
Cited by: 60 articles | PMID: 2659823
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Fibrinolysis and cancer.
Kwaan HC, Keer HN
Semin Thromb Hemost, 16(3):230-235, 01 Jul 1990
Cited by: 36 articles | PMID: 2146746
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Elevated transferrin receptor content in human prostate cancer cell lines assessed in vitro and in vivo.
Keer HN, Kozlowski JM, Tsai YC, Lee C, McEwan RN, Grayhack JT
J Urol, 143(2):381-385, 01 Feb 1990
Cited by: 57 articles | PMID: 1688956
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Effect of localized hyperthermia on TA3Ha tumor transplanted subcutaneously in the tails of mice.
Murthy MS, Keer HN, Travis JD, Cohen JD, Mollick JA, Khandekar JD, Scanlon EF
Cancer Res, 44(9):3836-3840, 01 Sep 1984
Cited by: 4 articles | PMID: 6744300
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