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Search life-sciences literature (45,104,145 articles, preprints and more)

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Tofacitinib Safety and Effectiveness in Canadian Patients with Rheumatoid Arthritis by Cardiovascular Risk Enrichment: Subanalysis of the CANTORAL Study.
Haraoui B, Khraishi M, Choquette D, Fortin I, Kinch CD, Galos C, Roy P, Gruben D, Vaillancourt J, Sampalis JS, Keystone EC
Rheumatol Ther, 11(6):1629-1648, 01 Nov 2024
Cited by: 0 articles | PMID: 39485671 | PMCID: PMC11557792
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Pharmacokinetics and Safety of Intravenous Candidate Biosimilar CT-P47 and Reference Tocilizumab: A Randomized, Double-Blind, Phase 1 Study.
Haranaka M, Eto T, Tanaka T, Yazawa R, Burmester G, Keystone E, Kim S, Bae Y, Suh J, Yang G, Kim Y, Lee J, Smolen JS
J Clin Pharmacol, 16 Oct 2024
Cited by: 0 articles | PMID: 39415551
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Efficacy and safety of CT-P47 versus reference tocilizumab: 32-week results of a randomised, active-controlled, double-blind, phase III study in patients with rheumatoid arthritis, including 8 weeks of switching data from reference tocilizumab to CT-P47.
Smolen JS, Trefler J, Racewicz A, Jaworski J, Zielińska A, Krogulec M, Jeka S, Wojciechowski R, Kolossa K, Dudek A, Krajewska-Włodarczyk M, Hrycaj P, Klimiuk PA, Burmester GR, Kim S, Bae Y, Yang G, Jung Y, Hong J, Keystone E
RMD Open, 10(4):e004514, 18 Oct 2024
Cited by: 0 articles | PMID: 39424404 | PMCID: PMC11492937
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Pharmacokinetics and safety of candidate tocilizumab biosimilar CT-P47 administered by auto-injector or pre-filled syringe: a randomized, open‑label, single-dose phase I study.
Yu KS, Ryu H, Shin D, Park M, Hwang J, Moon SJ, Kim MG, Keystone E, Smolen JS, Kim S, Bae Y, Jeon D, Jang J, Yang G, Bae J, Lee J, Burmester GR
Expert Opin Biol Ther, 24(7):681-689, 21 Jun 2024
Cited by: 0 articles | PMID: 38905143
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Impact of anti-rheumatic treatment on the individual components of the ACR composite score in patients with rheumatoid arthritis: real-world data.
Movahedi M, Choquette D, Coupal L, Keystone E, Bombardier C, Bessette L
Clin Exp Rheumatol, 42(9):1820-1829, 06 Jun 2024
Cited by: 0 articles | PMID: 38855967
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Risk factors for prevalent and incident hypertension in rheumatoid arthritis: data from the Canadian Early Arthritis Cohort.
Hadwen B, Stranges S, Pope JE, Bartlett S, Boire G, Bessette L, Hitchon CA, Hazlewood G, Keystone EC, Schieir O, Thorne C, Tin D, Valois MF, Bykerk V, Barra L, CATCH Investigators
Rheumatol Adv Pract, 8(2):rkae066, 22 May 2024
Cited by: 0 articles | PMID: 38895593 | PMCID: PMC11183658
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Having More Tender Than Swollen Joints Is Associated With Worse Patient-Reported Outcomes in Patients With Early RA.
Meng CF, Lee YC, Schieir O, Valois MF, Butler MA, Boire G, Hazlewood G, Hitchon C, Keystone E, Tin D, Thorne C, Bessette L, Pope J, Bartlett SJ, Bykerk VP, Canadian Early Arthritis Cohort Investigators
J Clin Rheumatol, 30(5):193-199, 01 May 2024
Cited by: 0 articles | PMID: 38689390
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Effects of nintedanib in patients with limited cutaneous systemic sclerosis and interstitial lung disease.
Allanore Y, Khanna D, Smith V, Aringer M, Hoffmann-Vold AM, Kuwana M, Merkel PA, Stock C, Sambevski S, Denton CP, SENSCIS Trial Investigators
Rheumatology (Oxford), 63(3):639-647, 01 Mar 2024
Cited by: 1 article | PMID: 37294870 | PMCID: PMC10907814
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Having More Tender Than Swollen Joints is Associated With Worse Function and Work Impairment in Patients With Early Rheumatoid Arthritis.
Meng CF, Lee Y, Schieir O, Valois MF, Butler M, Boire G, Hazlewood G, Hitchon C, Keystone E, Tin D, Thorne C, Bessette L, Pope J, Bartlett S, Bykerk V
ACR Open Rheumatol, 6(6):347-355, 06 Mar 2024
Cited by: 1 article | PMID: 38446125
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Does the Type of Failure and the Choice of the Second Biologic Influence Response and Persistence on Medication in Rheumatoid Arthritis?
Bessette L, Movahedi M, Reed G, Kremer JM, Kane K, Keystone E
J Clin Rheumatol, 29(7):332-340, 24 Aug 2023
Cited by: 0 articles | PMID: 37644656
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Efficacy of subcutaneous vs intravenous infliximab in rheumatoid arthritis: a post-hoc analysis of a randomized phase III trial.
Constantin A, Caporali R, Edwards CJ, Fonseca JE, Iannone F, Keystone E, Schulze-Koops H, Kwon T, Kim S, Yoon S, Kim DH, Park G, Yoo DH
Rheumatology (Oxford), 62(8):2838-2844, 01 Aug 2023
Cited by: 1 article | PMID: 36534825 | PMCID: PMC10393429
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Safety and efficacy of filgotinib for Japanese patients with RA and inadequate response to MTX: FINCH 1 52-week results and FINCH 4 48-week results.
Tanaka Y, Matsubara T, Atsumi T, Amano K, Ishiguro N, Sugiyama E, Yamaoka K, Combe BG, Kivitz AJ, Bae SC, Keystone EC, Nash P, Genovese M, Matzkies F, Bartok B, Pechonkina A, Kondo A, Ye L, Gong Q, [...] Takeuchi T
Mod Rheumatol, 33(4):668-679, 01 Jul 2023
Cited by: 2 articles | PMID: 35920102
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Pharmacokinetics and safety of candidate tocilizumab biosimilar CT-P47 versus reference tocilizumab: a randomized, double-blind, single-dose phase I study.
Yu KS, Kim B, Shin D, Park MK, Hwang JG, Kim MG, Chung H, Ghim J, Chung JY, Smolen JS, Burmester GR, Kim S, Bae Y, Jeon D, Yoo J, Yang G, Bae J, Keystone E
Expert Opin Investig Drugs, 32(5):429-439, 26 May 2023
Cited by: 2 articles | PMID: 37231670
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Impact of the COVID-19 pandemic on patients with rheumatoid arthritis: data from the Ontario Best Practices Research Initiative (OBRI).
Wong-Pack M, Hepworth E, Movahedi M, Kuriya B, Pope J, Keystone E, Thorne C, Ahluwalia V, Cesta A, Mously C, Bombardier C, Lau A, Aydin SZ
Rheumatol Adv Pract, 7(2):rkad042, 26 Apr 2023
Cited by: 0 articles | PMID: 37179654 | PMCID: PMC10172034
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Discontinuation of tofacitinib and TNF inhibitors in patients with rheumatoid arthritis: analysis of pooled data from two registries in Canada.
Movahedi M, Choquette D, Coupal L, Cesta A, Li X, Keystone EC, Bombardier C, Investigators O
BMJ Open, 13(3):e063198, 06 Mar 2023
Cited by: 4 articles | PMID: 36878650 | PMCID: PMC9990670
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The Proportion of Patients With Rheumatoid Arthritis Achieving ACR20/50/70; Consistent Patterns of a 60/40/20 as Demonstrated by a Systematic Review and Meta-analysis.
Mokbel A, Movahedi M, Philippopoulos E, Ojani P, Keystone EC
J Clin Rheumatol, 29(4):183-189, 06 Mar 2023
Cited by: 0 articles | PMID: 36870081
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Reducing cardiovascular risk with immunomodulators: a randomised active comparator trial among patients with rheumatoid arthritis.
Solomon DH, Giles JT, Liao KP, Ridker PM, Rist PM, Glynn RJ, Broderick R, Lu F, Murray MT, Vanni K, Santacroce LM, Abohashem S, Robson PM, Fayad Z, Mani V, Tawakol A, Bathon J, TARGET Trial Consortium
Ann Rheum Dis, 82(3):324-330, 30 Nov 2022
Cited by: 16 articles | PMID: 36450449 | PMCID: PMC9933165
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Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.
Ishigaki K, Sakaue S, Terao C, Luo Y, Sonehara K, Yamaguchi K, Amariuta T, Too CL, Laufer VA, Scott IC, Viatte S, Takahashi M, Ohmura K, Murasawa A, Hashimoto M, Ito H, Hammoudeh M, Emadi SA, Masri BK, [...] Raychaudhuri S
Nat Genet, 54(11):1640-1651, 04 Nov 2022
Cited by: 82 articles | PMID: 36333501 | PMCID: PMC10165422
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Effectiveness and Safety of Tofacitinib in Canadian Patients With Rheumatoid Arthritis: Primary Results From a Prospective Observational Study.
Haraoui B, Khraishi M, Choquette D, Lisnevskaia L, Teo M, Kinch C, Galos C, Roy P, Gruben D, Woolcott JC, Vaillancourt J, Sampalis JS, Keystone EC, Canadian Tofacitinib for Rheumatoid Arthritis Observational Investigators
Arthritis Care Res (Hoboken), 75(2):240-251, 10 Oct 2022
Cited by: 2 articles | PMID: 35678771 | PMCID: PMC10091934
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"From Where I Stand": using multiple anchors yields different benchmarks for meaningful improvement and worsening in the rheumatoid arthritis flare questionnaire (RA-FQ).
Bartlett SJ, Bykerk VP, Schieir O, Valois MF, Pope JE, Pope JE, Boire G, Hitchon C, Hazlewood G, Bessette L, Keystone E, Thorne C, Tin D, Bingham CO, CATCH Investigators
Qual Life Res, 32(5):1307-1318, 08 Sep 2022
Cited by: 0 articles | PMID: 36074252
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Medical cannabis use by rheumatology patients in routine clinical care: results from The Ontario Best Practices Research Initiative.
Rampakakis E, Thorne C, Cesta A, Movahedi M, Li X, Mously C, Ahluwalia V, Brophy J, Ciaschini P, Keystone E, Lau A, Major G, Pavlova V, Pope JE, Bombardier C
Clin Exp Rheumatol, 41(1):118-125, 23 May 2022
Cited by: 2 articles | PMID: 35616591
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Statin Use for Primary Cardiovascular Disease Prevention Is Low in Inflammatory Arthritis.
Kuriya B, Akhtari S, Movahedi M, Udell JA, Lawler PR, Farkouh ME, Keystone EC, Hanneman K, Nguyen E, Harvey PJ, Eder L
Can J Cardiol, 38(8):1244-1252, 13 Apr 2022
Cited by: 0 articles | PMID: 35429590
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Differential influence of Clinical Disease Activity Index components based on disease state in rheumatoid arthritis patients: real-world results from the Ontario Best Practices Research Initiative.
Keystone E, Movahedi M, Cesta A, Bombardier C, Sampalis JS, Rampakakis E
Clin Exp Rheumatol, 40(11):2147-2152, 30 Mar 2022
Cited by: 1 article | PMID: 35383561
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Efficacy and safety of switching from reference adalimumab to CT-P17 (100 mg/ml): 52-week randomized, double-blind study in rheumatoid arthritis.
Furst DE, Jaworski J, Wojciechowski R, Wiland P, Dudek A, Krogulec M, Jeka S, Zielinska A, Trefler J, Bartnicka-Maslowska K, Krajewska-Wlodarczyk M, Klimiuk PA, Lee SJ, Kim SH, Bae YJ, Yang GE, Yoo JK, Kay J, Keystone E
Rheumatology (Oxford), 61(4):1385-1395, 01 Apr 2022
Cited by: 5 articles | PMID: 34142111 | PMCID: PMC8996790
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Predictors of Influenza Vaccination in Early Rheumatoid Arthritis 2017-2021: Results From the Canadian Early Arthritis Cohort.
Ta V, Schieir O, Valois MF, Colmegna I, Hitchon C, Bessette L, Hazlewood G, Thorne C, Pope J, Boire G, Tin D, Keystone EC, Bykerk VP, Bartlett SJ
ACR Open Rheumatol, 4(7):566-573, 29 Mar 2022
Cited by: 1 article | PMID: 35349768 | PMCID: PMC9274339
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