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The "Great Debate" at Immunotherapy Bridge 2022, Naples, November 30th-December 1st, 2022.
Ascierto PA, Brentjens R, Khleif SN, Odunsi K, Rezvani K, Ruella M, Sullivan RJ, Fox BA, Puzanov I
J Transl Med, 21(1):275, 22 Apr 2023
Cited by: 1 article | PMID: 37087493 | PMCID: PMC10122806
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Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st-2nd, 2021.
Ascierto PA, Avallone A, Bhardwaj N, Bifulco C, Bracarda S, Brody JD, Buonaguro L, Demaria S, Emens LA, Ferris RL, Galon J, Khleif SN, Klebanoff CA, Laskowski T, Melero I, Paulos CM, Pignata S, Ruella M, Svane IM, [...] Puzanov I
J Transl Med, 20(1):257, 07 Jun 2022
Cited by: 2 articles | PMID: 35672823 | PMCID: PMC9172186
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IDO Vaccine Ablates Immune-Suppressive Myeloid Populations and Enhances Antitumor Effects Independent of Tumor Cell IDO Status.
Nandre R, Verma V, Gaur P, Patil V, Yang X, Ramlaoui Z, Shobaki N, Andersen MH, Pedersen AW, Zocca MB, Mkrtichyan M, Gupta S, Khleif SN
Cancer Immunol Res, 10(5):571-580, 01 May 2022
Cited by: 10 articles | PMID: 35290437 | PMCID: PMC9381100
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Clinical Evidence Generation During a Pandemic: Lessons Learned for Sustaining Progress.
Rivera DR, Kluetz PG, Abdallah K, Agrawal S, Angus DC, Califf RM, Garrett-Mayer E, Hyer R, Lowy DR, Khleif SN
Cancer J, 28(2):151-156, 01 Mar 2022
Cited by: 1 article | PMID: 35333502 | PMCID: PMC9158733
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PI3K Isoforms in CD8⁺ T Cell Development and Function.
Gaur P, Mkrtichyan M, Verma V, Jafarzadeh N, Hattar M, Gupta S, Khleif SN
Curr Top Microbiol Immunol, 436:217-234, 01 Jan 2022
Cited by: 0 articles | PMID: 36243846
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Translational Advances in Cancer Prevention Agent Development (TACPAD) Virtual Workshop on Immunomodulatory Agents: Report.
Mohammed A, Dashwood RH, Dickinson S, Disis ML, Jaffee EM, Johnson BD, Khleif SN, Pollak MN, Schlom J, Shoemaker RH, Stanton SE, Wondrak GT, You M, Zhu H, Miller MS
J Cancer Prev, 26(4):309-317, 01 Dec 2021
Cited by: 1 article | PMID: 35047458 | PMCID: PMC8749317
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Perspectives in immunotherapy: meeting report from the immunotherapy bridge (December 2nd-3rd, 2020, Italy).
Ascierto PA, Bifulco C, Ciardiello F, Demaria S, Emens LA, Ferris R, Formenti SC, Galon J, Khleif SN, Kirchhoff T, McQuade J, Odunsi K, Patnaik A, Paulos CM, Taube JM, Timmerman J, Fox BA, Hwu P, Puzanov I
J Transl Med, 19(1):238, 02 Jun 2021
Cited by: 2 articles | PMID: 34078406 | PMCID: PMC8173810
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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose?
Demaria S, Guha C, Schoenfeld J, Morris Z, Monjazeb A, Sikora A, Crittenden M, Shiao S, Khleif S, Gupta S, Formenti SC, Vikram B, Coleman CN, Ahmed MM
J Immunother Cancer, 9(4):e002038, 01 Apr 2021
Cited by: 94 articles | PMID: 33827904 | PMCID: PMC8031689
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Perspectives in immunotherapy: meeting report from the "Immunotherapy Bridge" (December 4th-5th, 2019, Naples, Italy).
Ascierto PA, Butterfield LH, Campbell K, Daniele B, Dougan M, Emens LA, Formenti S, Janku F, Khleif SN, Kirchhoff T, Morabito A, Najjar Y, Nathan P, Odunsi K, Patnaik A, Paulos CM, Reinfeld BI, Skinner HD, Timmerman J, Puzanov I
J Transl Med, 19(1):13, 06 Jan 2021
Cited by: 2 articles | PMID: 33407605 | PMCID: PMC7789268
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Shifting the Immune-Suppressive to Predominant Immune-Stimulatory Radiation Effects by SBRT-PArtial Tumor Irradiation Targeting HYpoxic Segment (SBRT-PATHY).
Tubin S, Gupta S, Grusch M, Popper HH, Brcic L, Ashdown ML, Khleif SN, Peter-Vörösmarty B, Hyden M, Negrini S, Fossati P, Hug E
Cancers (Basel), 13(1):E50, 26 Dec 2020
Cited by: 21 articles | PMID: 33375357 | PMCID: PMC7795882
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The State of Melanoma: Emergent Challenges and Opportunities.
Atkins MB, Curiel-Lewandrowski C, Fisher DE, Swetter SM, Tsao H, Aguirre-Ghiso JA, Soengas MS, Weeraratna AT, Flaherty KT, Herlyn M, Sosman JA, Tawbi HA, Pavlick AC, Cassidy PB, Chandra S, Chapman PB, Daud A, Eroglu Z, Ferris LK, [...] Melanoma Research Foundation
Clin Cancer Res, 27(10):2678-2697, 07 Jan 2021
Cited by: 38 articles | PMID: 33414132 | PMCID: PMC8127340
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MEK inhibition reprograms CD8⁺ T lymphocytes into memory stem cells with potent antitumor effects.
Verma V, Jafarzadeh N, Boi S, Kundu S, Jiang Z, Fan Y, Lopez J, Nandre R, Zeng P, Alolaqi F, Ahmad S, Gaur P, Barry ST, Valge-Archer VE, Smith PD, Banchereau J, Mkrtichyan M, Youngblood B, Rodriguez PC, [...] Khleif SN
Nat Immunol, 22(1):53-66, 23 Nov 2020
Cited by: 88 articles | PMID: 33230330 | PMCID: PMC10081014
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Early 3+3 Trial Dose-Escalation Phase I Clinical Trial Design and Suitability for Immune Checkpoint Inhibitors.
Rahma OE, Reuss JE, Giobbie-Hurder A, Shoja E Razavi G, Abu-Shawer O, Mehra P, Gupta S, Simon R, Khleif SN
Clin Cancer Res, 27(2):485-491, 20 Oct 2020
Cited by: 3 articles | PMID: 33082209
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Clinical Application of Computational Methods in Precision Oncology: A Review.
Panagiotou OA, Högg LH, Hricak H, Khleif SN, Levy MA, Magnus D, Murphy MJ, Patel B, Winn RA, Nass SJ, Gatsonis C, Cogle CR
JAMA Oncol, 6(8):1282-1286, 01 Aug 2020
Cited by: 6 articles | PMID: 32407443
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The Great Debate at 'Immunotherapy Bridge', Naples, December 5, 2019.
Ascierto PA, Bifulco C, Galon J, Garbe C, Khleif SN, McQuade J, Odunsi K, Okada H, Paulos CM, Quezada SA, Tawbi HA, Timmerman J, Trinchieri G, Butterfield LH, Puzanov I
J Immunother Cancer, 8(2):e000921, 01 Aug 2020
Cited by: 1 article | PMID: 32843491 | PMCID: PMC7449295
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Randomized Phase II Trial of Nivolumab Versus Nivolumab and Ipilimumab for Recurrent or Persistent Ovarian Cancer: An NRG Oncology Study.
Zamarin D, Burger RA, Sill MW, Powell DJ, Lankes HA, Feldman MD, Zivanovic O, Gunderson C, Ko E, Mathews C, Sharma S, Hagemann AR, Khleif S, Aghajanian C
J Clin Oncol, 38(16):1814-1823, 10 Apr 2020
Cited by: 158 articles | PMID: 32275468 | PMCID: PMC7255977
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Phase II evaluation of nivolumab in the treatment of persistent or recurrent cervical cancer (NCT02257528/NRG-GY002).
Santin AD, Deng W, Frumovitz M, Buza N, Bellone S, Huh W, Khleif S, Lankes HA, Ratner ES, O'Cearbhaill RE, Jazaeri AA, Birrer M
Gynecol Oncol, 157(1):161-166, 07 Jan 2020
Cited by: 71 articles | PMID: 31924334 | PMCID: PMC7127981
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Phase II evaluation of copanlisib, a selective inhibitor of Pi3kca, in patients with persistent or recurrent endometrial carcinoma harboring PIK3CA hotspot mutations: An NRG Oncology study (NRG-GY008).
Santin AD, Filiaci V, Bellone S, Ratner ES, Mathews CA, Cantuaria G, Gunderson CC, Rutledge T, Buttin BM, Lankes HA, Frumovitz M, Khleif SN, Huh WK, Birrer MJ
Gynecol Oncol Rep, 31:100532, 02 Jan 2020
Cited by: 5 articles | PMID: 31934607 | PMCID: PMC6951478
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Author Correction: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1⁺CD38^hi cells and anti-PD-1 resistance.
Verma V, Shrimali RK, Ahmad S, Dai W, Wang H, Lu S, Nandre R, Gaur P, Lopez J, Sade-Feldman M, Yizhak K, Bjorgaard SL, Flaherty KT, Wargo JA, Boland GM, Sullivan RJ, Getz G, Hammond SA, Tan M, [...] Khleif SN
Nat Immunol, 20(11):1555, 01 Nov 2019
Cited by: 3 articles | PMID: 31551574
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PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1⁺CD38^hi cells and anti-PD-1 resistance.
Verma V, Shrimali RK, Ahmad S, Dai W, Wang H, Lu S, Nandre R, Gaur P, Lopez J, Sade-Feldman M, Yizhak K, Bjorgaard SL, Flaherty KT, Wargo JA, Boland GM, Sullivan RJ, Getz G, Hammond SA, Tan M, [...] Khleif SN
Nat Immunol, 20(9):1231-1243, 29 Jul 2019
Cited by: 170 articles | PMID: 31358999 | PMCID: PMC7472661
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Clinical Activity, Tolerability, and Long-Term Follow-Up of Durvalumab in Patients With Advanced NSCLC.
Antonia SJ, Balmanoukian A, Brahmer J, Ou SI, Hellmann MD, Kim SW, Ahn MJ, Kim DW, Gutierrez M, Liu SV, Schöffski P, Jäger D, Jamal R, Jerusalem G, Lutzky J, Nemunaitis J, Calabrò L, Weiss J, Gadgeel S, [...] Segal NH
J Thorac Oncol, 14(10):1794-1806, 20 Jun 2019
Cited by: 51 articles | PMID: 31228626
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Safety and efficacy of durvalumab in patients with head and neck squamous cell carcinoma: results from a phase I/II expansion cohort.
Segal NH, Ou SI, Balmanoukian A, Fury MG, Massarelli E, Brahmer JR, Weiss J, Schöffski P, Antonia SJ, Massard C, Zandberg DP, Khleif SN, Xiao F, Rebelatto MC, Steele KE, Robbins PB, Angra N, Song X, Abdullah S, Butler M
Eur J Cancer, 109:154-161, 04 Feb 2019
Cited by: 44 articles | PMID: 30731276
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SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art.
Butterfield LH, Disis ML, Fox BA, Kaufman DR, Khleif SN, Wang E, Society for Immunotherapy of Cancer Immuno-Oncology Biomarkers: State of the Art workshop speakers
J Immunother Cancer, 6(1):138, 04 Dec 2018
Cited by: 12 articles | PMID: 30514399 | PMCID: PMC6278162
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Radiation, Immune Checkpoint Blockade and the Abscopal Effect: A Critical Review on Timing, Dose and Fractionation.
Buchwald ZS, Wynne J, Nasti TH, Zhu S, Mourad WF, Yan W, Gupta S, Khleif SN, Khan MK
Front Oncol, 8:612, 13 Dec 2018
Cited by: 105 articles | PMID: 30619752 | PMCID: PMC6306034
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Phase Ia study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) in patients with recurrent advanced solid tumors.
Nayak-Kapoor A, Hao Z, Sadek R, Dobbins R, Marshall L, Vahanian NN, Jay Ramsey W, Kennedy E, Mautino MR, Link CJ, Lin RS, Royer-Joo S, Liang X, Salphati L, Morrissey KM, Mahrus S, McCall B, Pirzkall A, Munn DH, [...] Khleif SN
J Immunother Cancer, 6(1):61, 20 Jun 2018
Cited by: 66 articles | PMID: 29921320 | PMCID: PMC6009946
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