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Search life-sciences literature (45,103,589 articles, preprints and more)

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Uridine-cytidine kinase 2 potentiates the mutagenic influence of the antiviral β-d-N4-hydroxycytidine.
Xu Z, Flensburg C, Bilardi RA, Majewski IJ
Nucleic Acids Res, 51(22):12031-12042, 01 Dec 2023
Cited by: 0 articles | PMID: 37953355 | PMCID: PMC10711452
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Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition.
Abdulla HD, Alserihi R, Flensburg C, Abeysekera W, Luo MX, Gray DHD, Liu X, Smyth GK, Alexander WS, Majewski IJ, McCormack MP
J Exp Med, 220(6):e20212383, 15 Mar 2023
Cited by: 3 articles | PMID: 36920307 | PMCID: PMC10037042
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Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies.
Fang H, Yan HHN, Bilardi RA, Flensburg C, Yang H, Barbour JA, Siu HC, Turski M, Chew E, Xu Z, Lam ST, Sharma R, Xu M, Li J, Ip HW, Cheung CYM, Huen MSY, Sweet-Cordero EA, Majewski IJ, [...] Wong JWH
Genome Med, 14(1):124, 31 Oct 2022
Cited by: 5 articles | PMID: 36316687 | PMCID: PMC9620652
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Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy.
Thijssen R, Tian L, Anderson MA, Flensburg C, Jarratt A, Garnham AL, Jabbari JS, Peng H, Lew TE, Teh CE, Gouil Q, Georgiou A, Tan T, Djajawi TM, Tam CS, Seymour JF, Blombery P, Gray DHD, Majewski IJ, [...] Huang DCS
Blood, 140(20):2127-2141, 01 Nov 2022
Cited by: 32 articles | PMID: 35709339 | PMCID: PMC10653037
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ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia.
Schmidt B, Brown LM, Ryland GL, Lonsdale A, Kosasih HJ, Ludlow LE, Majewski IJ, Blombery P, Ekert PG, Davidson NM, Oshlack A
Blood Adv, 6(14):4093-4097, 01 Jul 2022
Cited by: 24 articles | PMID: 35482550 | PMCID: PMC9327546
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Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.
Palles C, West HD, Chew E, Galavotti S, Flensburg C, Grolleman JE, Jansen EAM, Curley H, Chegwidden L, Arbe-Barnes EH, Lander N, Truscott R, Pagan J, Bajel A, Sherwood K, Martin L, Thomas H, Georgiou D, Fostira F, [...] de Voer RM
Am J Hum Genet, 109(5):953-960, 22 Apr 2022
Cited by: 20 articles | PMID: 35460607 | PMCID: PMC9118112
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Detecting copy number alterations in RNA-Seq using SuperFreq.
Flensburg C, Oshlack A, Majewski IJ
Bioinformatics, 37(22):4023-4032, 01 Nov 2021
Cited by: 7 articles | PMID: 34132781
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MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data.
Cmero M, Schmidt B, Majewski IJ, Ekert PG, Oshlack A, Davidson NM
Genome Biol, 22(1):296, 22 Oct 2021
Cited by: 13 articles | PMID: 34686194 | PMCID: PMC8532352
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ALLSorts: a RNA-Seq classifier for B-Cell Acute Lymphoblastic Leukemia
Schmidt B, Brown LM, Ryland GL, Lonsdale A, Kosasih HJ, Ludlow LE, Majewski IJ, Blombery P, Ekert PG, Davidson NM, Oshlack A
bioRxiv, 01 Aug 2021
Cited by: 0 articles | PPR: PPR377337
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The crux of Cux1 in myeloid neoplasms.
Majewski IJ
Blood, 138(9):743-744, 01 Sep 2021
Cited by: 0 articles | PMID: 34473232
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CHK2 Inhibition Provides a Strategy to Suppress Hematologic Toxicity from PARP Inhibitors.
Xu Z, Vandenberg CJ, Lieschke E, Di Rago L, Scott CL, Majewski IJ
Mol Cancer Res, 19(8):1350-1360, 16 Apr 2021
Cited by: 10 articles | PMID: 33863812
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Germline loss-of-function variants in the base-excision repair geneMBD4cause a Mendelian recessive syndrome of adenomatous colorectal polyposis and acute myeloid leukaemia
Palles C, Chew E, Grolleman JE, Galavotti S, Flensburg C, Jansen EA, Curley H, Chegwidden L, Barnes EA, Bajel A, Sherwood K, Martin L, Thomas H, Georgiou D, Fostira F, Goldberg Y, Adams DJ, van der Biezen SA, Christie M, [...] de Voer RM
bioRxiv, 28 Apr 2021
Cited by: 0 articles | PPR: PPR316218
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Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias.
Thijssen R, Diepstraten ST, Moujalled D, Chew E, Flensburg C, Shi MX, Dengler MA, Litalien V, MacRaild S, Chen M, Anstee NS, Reljić B, Gabriel SS, Djajawi TM, Riffkin CD, Aubrey BJ, Chang C, Tai L, Xu Z, [...] Wei AH
Blood, 137(20):2721-2735, 01 May 2021
Cited by: 56 articles | PMID: 33824975 | PMCID: PMC8138548
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Life without mismatch repair
Sanders MA, Vöhringer H, Forster VJ, Moore L, Campbell BB, Hooks Y, Edwards M, Bianchi V, Coorens THH, Butler TM, Lee-Six H, Robinson PS, Flensburg C, Bilardi RA, Majewski IJ, Reschke A, Cairney E, Crooks B, Lindhorst S, [...] Campbell PJ
bioRxiv, 15 Apr 2021
Cited by: 0 articles | PPR: PPR312491
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Finding a suitable library size to call variants in RNA-Seq.
Quaglieri A, Flensburg C, Speed TP, Majewski IJ
BMC Bioinformatics, 21(1):553, 01 Dec 2020
Cited by: 3 articles | PMID: 33261552 | PMCID: PMC7708150
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Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy.
Chua CC, Roberts AW, Reynolds J, Fong CY, Ting SB, Salmon JM, MacRaild S, Ivey A, Tiong IS, Fleming S, Brown FC, Loo S, Majewski IJ, Bohlander SK, Wei AH
J Clin Oncol, 38(30):3506-3517, 20 Jul 2020
Cited by: 75 articles | PMID: 32687450
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MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data
Cmero M, Schmidt B, Majewski IJ, Ekert PG, Oshlack A, Davidson NM
bioRxiv, 04 Jun 2020
Cited by: 0 articles | PPR: PPR171244
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A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction.
Hildebrand JM, Kauppi M, Majewski IJ, Liu Z, Cox AJ, Miyake S, Petrie EJ, Silk MA, Li Z, Tanzer MC, Brumatti G, Young SN, Hall C, Garnish SE, Corbin J, Stutz MD, Di Rago L, Gangatirkar P, Josefsson EC, [...] Silke J
Nat Commun, 11(1):3150, 19 Jun 2020
Cited by: 59 articles | PMID: 32561755 | PMCID: PMC7305203
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CHK2 inhibition provides a strategy to suppress hematological toxicity from PARP inhibitors
Xu Z, Vandenberg CJ, Lieschke E, Scott CL, Majewski IJ
bioRxiv, 29 Jul 2020
Cited by: 0 articles | PPR: PPR194071
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SuperFreq: Integrated mutation detection and clonal tracking in cancer.
Flensburg C, Sargeant T, Oshlack A, Majewski IJ
PLoS Comput Biol, 16(2):e1007603, 13 Feb 2020
Cited by: 30 articles | PMID: 32053599 | PMCID: PMC7043783
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Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML.
DiNardo CD, Tiong IS, Quaglieri A, MacRaild S, Loghavi S, Brown FC, Thijssen R, Pomilio G, Ivey A, Salmon JM, Glytsou C, Fleming SA, Zhang Q, Ma H, Patel KP, Kornblau SM, Xu Z, Chua CC, Chen X, [...] Wei AH
Blood, 135(11):791-803, 01 Mar 2020
Cited by: 296 articles | PMID: 31932844 | PMCID: PMC7068032
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Detecting copy number alterations in RNA-Seq using SuperFreq
Flensburg C, Oshlack A, Majewski IJ
bioRxiv, 01 Jun 2020
Cited by: 0 articles | PPR: PPR169819
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The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia.
Brown LM, Lonsdale A, Zhu A, Davidson NM, Schmidt B, Hawkins A, Wallach E, Martin M, Mechinaud FM, Khaw SL, Bartolo RC, Ludlow LEA, Challis J, Brooks I, Petrovic V, Venn NC, Sutton R, Majewski IJ, Oshlack A, Ekert PG
Blood Adv, 4(5):930-942, 01 Mar 2020
Cited by: 37 articles | PMID: 32150610 | PMCID: PMC7065479
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Finding a suitable library size to call variants in RNA-seq
Quaglieri A, Flensburg C, Speed TP, Majewski IJ
bioRxiv, 19 Dec 2019
Cited by: 0 articles | PPR: PPR106358
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Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.
Birkinshaw RW, Gong JN, Luo CS, Lio D, White CA, Anderson MA, Blombery P, Lessene G, Majewski IJ, Thijssen R, Roberts AW, Huang DCS, Colman PM, Czabotar PE
Nat Commun, 10(1):2385, 03 Jun 2019
Cited by: 86 articles | PMID: 31160589 | PMCID: PMC6547681
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