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Search life-sciences literature (45,104,206 articles, preprints and more)

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MDM2 Inhibitors for Cancer Therapy: The Past, Present, and Future.
Wang W, Albadari N, Du Y, Fowler JF, Sang HT, Xian W, McKeon F, Li W, Zhou J, Zhang R
Pharmacol Rev, 76(3):414-453, 02 May 2024
Cited by: 5 articles | PMID: 38697854 | PMCID: PMC11068841
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Editorial Expression of Concern: The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin.
Ryeom S, Greenwald RJ, Sharpe AH, McKeon F
Nat Immunol, 25(5):929, 01 May 2024
Cited by: 0 articles | PMID: 38467831
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Editorial Expression of Concern: p63 and p73 are required for p53-dependent apoptosis in response to DNA damage.
Flores ER, Tsai KY, Crowley D, Sengupta S, Yang A, McKeon F, Jacks T
Nature, 627(8004):E10, 01 Mar 2024
Cited by: 0 articles | PMID: 38418890
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Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lungs Is Not Resolved by CFTR Modulators.
Wang S, Niroula S, Hoffman A, Khorrami M, Khorrami M, Yuan F, Gasser GN, Choi S, Liu B, Li J, Metersky ML, Vincent M, Crum CP, Boucher RC, Karmouty-Quintana H, Huang HJ, Sheshadri A, Dickey BF, Parekh KR, [...] Xian W
Am J Respir Crit Care Med, 208(9):930-943, 01 Nov 2023
Cited by: 6 articles | PMID: 37695863 | PMCID: PMC10870857
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Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis.
Wang S, Rao W, Hoffman A, Lin J, Li J, Lin T, Liew AA, Vincent M, Mertens TCJ, Karmouty-Quintana H, Crum CP, Metersky ML, Schwartz DA, Davies PJA, Stephan C, Jyothula SSK, Sheshadri A, Suarez EE, Huang HJ, [...] Xian W
Sci Transl Med, 15(693):eabp9528, 26 Apr 2023
Cited by: 4 articles | PMID: 37099633 | PMCID: PMC10794039
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Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment.
Fan Y, Li Y, Yao X, Jin J, Scott A, Liu B, Wang S, Huo L, Wang Y, Wang R, Pool Pizzi M, Ma L, Shao S, Sewastjanow-Silva M, Waters R, Chatterjee D, Liu B, Shanbhag N, Peng G, [...] Song S
Gut, 72(4):624-637, 24 Aug 2022
Cited by: 22 articles | PMID: 36002248
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Molecular targeting therapies for neuroblastoma: Progress and challenges.
Zafar A, Wang W, Liu G, Wang X, Xian W, McKeon F, Foster J, Zhou J, Zhang R
Med Res Rev, 41(2):961-1021, 06 Nov 2020
Cited by: 144 articles | PMID: 33155698 | PMCID: PMC7906923
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Targeting the p53-MDM2 pathway for neuroblastoma therapy: Rays of hope.
Zafar A, Wang W, Liu G, Xian W, McKeon F, Zhou J, Zhang R
Cancer Lett, 496:16-29, 29 Sep 2020
Cited by: 46 articles | PMID: 33007410 | PMCID: PMC8351219
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Protocol for Cloning Epithelial Stem Cell Variants from Human Lung.
Rao W, Niroula S, Wang S, Vincent M, McKeon F, Xian W
STAR Protoc, 1(2):100063, 09 Jul 2020
Cited by: 3 articles | PMID: 33015646 | PMCID: PMC7529324
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Mystery Solving: Acid Reflux and Cell Mobility in Barrett's Esophagus and Esophageal Adenocarcinoma.
Mckeon F, Xian W
Cell Mol Gastroenterol Hepatol, 10(3):639-640, 27 Jun 2020
Cited by: 0 articles | PMID: 32598898 | PMCID: PMC7474153
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Cloning of ground-state intestinal stem cells from endoscopic biopsy samples.
Duleba M, Yamamoto Y, Neupane R, Rao W, Xie J, Qi Y, Liew AA, Niroula S, Zhang Y, Mahalingam R, Wang S, Goller K, Ajani JA, Vincent M, Ho KY, Hou JK, Hyams JS, Sylvester FA, Crum CP, [...] Xian W
Nat Protoc, 15(5):1612-1627, 01 Apr 2020
Cited by: 4 articles | PMID: 32238950
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Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.
Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, Mahalingam R, Neupane R, Liew AA, Vincent M, Okuda K, O'Neal WK, Boucher RC, Dickey BF, Wechsler ME, Ibrahim O, Engelhardt JF, Mertens TCJ, Wang W, [...] Xian W
Cell, 181(4):848-864.e18, 15 Apr 2020
Cited by: 64 articles | PMID: 32298651 | PMCID: PMC7294989
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Microenvironment meets lineage complexity in junctional tumorigenesis.
Xian W, McKeon F
Nat Commun, 10(1):3829, 23 Aug 2019
Cited by: 1 article | PMID: 31444324 | PMCID: PMC6707302
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Unlimited expansion of intestinal stem cells from a wide range of ages.
Duleba M, Mahalingam R, Liew AA, Qi Y, Neupane R, Vincent M, Agarwal S, Sylvester FA, Hyams JS, Ho KY, Hou JK, McKeon F, Xian W
Integr Mol Med, 6(4), 15 Jul 2019
Cited by: 1 article | PMID: 31463081 | PMCID: PMC6713279
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Circadian period 2: a missing beneficial factor in sickle cell disease by lowering pulmonary inflammation, iron overload, and mortality.
Adebiyi MG, Zhao Z, Ye Y, Manalo J, Hong Y, Lee CC, Xian W, McKeon F, Culp-Hill R, D' Alessandro A, Kellems RE, Yoo SH, Han L, Xia Y
FASEB J, 33(9):10528-10537, 29 Jun 2019
Cited by: 2 articles | PMID: 31260634 | PMCID: PMC6988849
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Ground-State Stem Cells: A Novel Approach for Adult Stem Cell Research.
Xian W, Duleba M, Qi Y, Mahalingam R, Vincent M, McKeon F
J Pediatr Pediatr Med, 2(6):7-10, 31 Dec 2018
Cited by: 0 articles | PMID: 30957106 | PMCID: PMC6448798
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The Cellular Origin of Barrett's Esophagus and Its Stem Cells.
Xian W, Duleba M, Zhang Y, Yamamoto Y, Ho KY, Crum C, McKeon F
Adv Exp Med Biol, 1123:55-69, 01 Jan 2019
Cited by: 7 articles | PMID: 31016595
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Biobanking Organoids or Ground-State Stem Cells?
Xian W, Duleba M, Yamamoto Y, Vincent M, McKeon F
J Clin Med, 7(12):E555, 16 Dec 2018
Cited by: 0 articles | PMID: 30558346 | PMCID: PMC6306851
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An Efficient Method for Cloning Gastrointestinal Stem Cells From Patients via Endoscopic Biopsies.
Duleba M, Qi Y, Mahalingam R, Liew AA, Neupane R, Flynn K, Rinaldi F, Vincent M, Crum CP, Ho KY, Hou JK, Hyams JS, Sylvester FA, McKeon F, Xian W
Gastroenterology, 156(1):20-23, 06 Oct 2018
Cited by: 4 articles | PMID: 30296437 | PMCID: PMC6309951
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Demise of lung transplants: exposing critical gaps in understanding lung stem cells.
Xian W, McKeon F
J Thorac Dis, 10(suppl 9):S1016-S1019, 01 Apr 2018
Cited by: 0 articles | PMID: 29849224 | PMCID: PMC5949424
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TAp63 as a guardian of female germ line integrity.
Xian W, McKeon F
Nat Struct Mol Biol, 25(3):201-202, 01 Mar 2018
Cited by: 4 articles | PMID: 29507403
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CEACAM 6, a novel marker for the diagnosis of Barrett's esophagus.
Sharma N, Srivastava S, Kern F, Xian W, Yeoh KG, Ming T, McKeon F, Ho KY
Dis Esophagus, 30(7):1-5, 01 Jul 2017
Cited by: 3 articles | PMID: 28475729
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FABP1 and Hepar expression levels in Barrett's esophagus and associated neoplasia in an Asian population.
Srivastava S, Kern F, Sharma N, McKeon F, Xian W, Yeoh KG, Ho KY, Teh M
Dig Liver Dis, 49(10):1104-1109, 27 Jul 2017
Cited by: 6 articles | PMID: 28807490
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A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance.
Spechler SJ, Merchant JL, Wang TC, Chandrasoma P, Fox JG, Genta RM, Goldenring JR, Hayakawa Y, Kuipers EJ, Lund PK, McKeon F, Mills JC, Odze RD, Peek RM, Pham T, Que J, Rustgi AK, Shaheen NJ, Shivdasani RA, [...] Wright NA
Gastroenterology, 153(1):e6-e13, 03 Jun 2017
Cited by: 10 articles | PMID: 28583825 | PMCID: PMC5828164
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Barrett's Stem Cells as a Unique and Targetable Entity.
Xian W, McKeon F
Cell Mol Gastroenterol Hepatol, 4(1):161-164, 26 Apr 2017
Cited by: 3 articles | PMID: 28593188 | PMCID: PMC5454139
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