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Search life-sciences literature (45,100,050 articles, preprints and more)

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The integrated stress response promotes macrophage inflammation and migration in autoimmune diabetes
Wang JE, Muralidharan C, Nargis T, Enriquez JR, Anderson RM, Mirmira RG, Tersey SA
bioRxiv, 03 Nov 2024
Cited by: 0 articles | PPR: PPR934793
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Hypusinated and unhypusinated isoforms of eIF5A exert distinct effects in models of pancreas development and function
Anderson CM, Kulkarni A, Maier B, Huang F, Figatner K, Chakraborty A, Pratuangtham S, May SC, Tersey SA, Anderson RM, Mirmira RG
bioRxiv, 27 Oct 2024
Cited by: 0 articles | PPR: PPR931654
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12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice.
Nargis T, Muralidharan C, Enriquez JR, Wang JE, Kaylan KB, Chakraborty A, Pratuangtham S, Figatner K, Nelson JB, May SC, Nadler JL, Boxer MB, Maloney DJ, Tersey SA, Mirmira RG
JCI Insight, e185299, 12 Nov 2024
Cited by: 0 articles | PMID: 39531315
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Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8<sup>+</sup> T cell activity and biomarker during the evolution of type 1 diabetes.
Rao C, Cater DT, Roy S, Xu J, De Oliveira AG, Evans-Molina C, Piganelli JD, Eizirik DL, Mirmira RG, Sims EK
Diabetologia, 07 Nov 2024
Cited by: 0 articles | PMID: 39508879
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RNA Splicing Events in Circulation Distinguish Individuals with and without New-Onset Type 1 Diabetes.
Webb-Robertson BM, Wu W, Flores JE, Bramer LM, Syed F, Tersey SA, May SC, Sims EK, Evans-Molina C, Mirmira RG
J Clin Endocrinol Metab, dgae622, 10 Sep 2024
Cited by: 0 articles | PMID: 39252615
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Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes
Rao C, Cater DT, Roy S, Xu J, Olivera ADG, Evans-Molina C, Piganelli JD, Eizirik DL, Mirmira RG, Sims EK
bioRxiv, 19 Sep 2024
Cited by: 0 articles | PPR: PPR912430
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Free fatty acids accelerate β-cell death in type 1 diabetes
Elliott EC, Sakar S, Bramer L, Burnet M, Kim Y, Yi X, Estevao IL, Rewers M, Cambronne XA, Vehik K, Arrojo e Drigo R, Metz TO, Eizirik DL, Webb-Robertson BM, Mirmira RG, Nakayasu ES
medRxiv, 16 Sep 2024
Cited by: 0 articles | PPR: PPR911405
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12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice
Nargis T, Muralidharan C, Enriquez JR, Wang JE, Kaylan K, Chakraborty A, Pratuangtham S, Figatner K, Nelson JB, May SC, Nadler JL, Boxer MB, Maloney DJ, Tersey SA, Mirmira RG
bioRxiv, 28 Jul 2024
Cited by: 0 articles | PPR: PPR888035
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Inhibition of the eukaryotic initiation factor-2α kinase PERK decreases risk of autoimmune diabetes in mice.
Muralidharan C, Huang F, Enriquez JR, Wang JE, Nelson JB, Nargis T, May SC, Chakraborty A, Figatner KT, Navitskaya S, Anderson CM, Calvo V, Surguladze D, Mulvihill MJ, Yi X, Sarkar S, Oakes SA, Webb-Robertson BM, Sims EK, [...] Mirmira RG
J Clin Invest, 134(16):e176136, 18 Jun 2024
Cited by: 0 articles | PMID: 38889047 | PMCID: PMC11324307
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Analysis of the effect of hypusination in myeloid cells on colitis and colitis-associated cancer.
Gobert AP, Finley J, Asim M, Barry DP, Allaman MM, Hawkins CV, Williams KJ, Delagado AG, Mirmira RG, Zhao S, Piazuelo MB, Washington MK, Coburn LA, Wilson KT
Heliyon, 10(13):e33838, 27 Jun 2024
Cited by: 0 articles | PMID: 39027559 | PMCID: PMC11255582
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Beta cell dedifferentiation in type 1 diabetes: sacrificing function for survival?
Webster KL, Mirmira RG
Front Endocrinol (Lausanne), 15:1427723, 06 Jun 2024
Cited by: 0 articles | PMID: 38904049 | PMCID: PMC11187278
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Proinflammatory stress activates neutral sphingomyelinase 2 based generation of a ceramide-enriched β cell EV subpopulation
Xu J, Harris-Kawano A, Enriquez JR, Mirmira RG, Sims EK
bioRxiv, 18 Apr 2024
Cited by: 0 articles | PPR: PPR840141
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Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis.
Sarkar S, Deiter C, Kyle JE, Guney MA, Sarbaugh D, Yin R, Li X, Cui Y, Ramos-Rodriguez M, Nicora CD, Syed F, Juan-Mateu J, Muralidharan C, Pasquali L, Evans-Molina C, Eizirik DL, Webb-Robertson BM, Burnum-Johnson K, Orr G, [...] Nakayasu ES
Cell Commun Signal, 22(1):141, 21 Feb 2024
Cited by: 0 articles | PMID: 38383396 | PMCID: PMC10880366
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Reduction of chemokine CXCL9 expression by omega-3 fatty acids via ADP-ribosylhydrolase ARH3 in MIN6 insulin-producing cells
You Y, Sarkar S, Deiter C, Elliott EC, Nicora CD, Mirmira RG, Sussel L, Nakayasu ES
bioRxiv, 31 Jan 2024
Cited by: 0 articles | PPR: PPR796610
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Discordant Effects of Polyamine Depletion by DENSpm and DFMO on β-cell Cytokine Stress and Diabetes Outcomes in Mice.
Hammoud B, Nelson JB, May SC, Tersey SA, Mirmira RG
Endocrinology, 165(3):bqae001, 01 Jan 2024
Cited by: 1 article | PMID: 38195178
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Leukotriene B4 receptor 2 governs macrophage migration during tissue inflammation.
Ermis E, Nargis T, Webster K, Tersey SA, Anderson RM, Mirmira RG
J Biol Chem, 300(1):105561, 12 Dec 2023
Cited by: 1 article | PMID: 38097183 | PMCID: PMC10790086
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Protection of β cells against pro-inflammatory cytokine stress by the GDF15-ERBB2 signaling
Sarkar S, Syed F, Webb-Robertson B, Melchior JT, Chang G, Gritsenko M, Wang Y, Tsai C, Liu J, Yi X, Cui Y, Eizirik DL, Metz TO, Rewers M, Evans-Molina C, Mirmira RG, Nakayasu ES
medRxiv, 27 Nov 2023
Cited by: 0 articles | PPR: PPR765222
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Stress and human health in diabetes: A report from the 19^th Chicago Biomedical Consortium symposium.
Mirmira RG, Kulkarni RN, Xu P, Drossos T, Varady K, Knutson KL, Reutrakul S, Martyn-Nemeth P, Sargis RM, Wallia A, Tuchman AM, Weissberg-Benchell J, Danielson KK, Oakes SA, Thomas CC, Layden BT, May SC, Burbea Hoffmann M, Gatta E, [...] Philipson LH
J Clin Transl Sci, 7(1):e263, 20 Nov 2023
Cited by: 0 articles | PMID: 38229904 | PMCID: PMC10790105
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A proteomic meta-analysis refinement of plasma extracellular vesicles.
Vallejo MC, Sarkar S, Elliott EC, Henry HR, Powell SM, Diaz Ludovico I, You Y, Huang F, Payne SH, Ramanadham S, Sims EK, Metz TO, Mirmira RG, Nakayasu ES
Sci Data, 10(1):837, 28 Nov 2023
Cited by: 1 article | PMID: 38017024 | PMCID: PMC10684639
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Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes.
Sims EK, Kulkarni A, Hull A, Woerner SE, Cabrera S, Mastrandrea LD, Hammoud B, Sarkar S, Nakayasu ES, Mastracci TL, Perkins SM, Ouyang F, Webb-Robertson BJ, Enriquez JR, Tersey SA, Evans-Molina C, Long SA, Blanchfield L, Gerner EW, [...] DiMeglio LA
Cell Rep Med, 4(11):101261, 01 Nov 2023
Cited by: 6 articles | PMID: 37918404 | PMCID: PMC10694631
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KDM2A Deficiency in the Liver Promotes Abnormal Liver Function and Potential Liver Damage.
Martin M, Motolani A, Kim HG, Collins AM, Alipourgivi F, Jin J, Wei H, Wood BA, Ma YY, Dong XC, Mirmira RG, Lu T
Biomolecules, 13(10):1457, 27 Sep 2023
Cited by: 0 articles | PMID: 37892137 | PMCID: PMC10604476
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Inhibition of the Eukaryotic Initiation Factor-2-α Kinase PERK Decreases Risk of Autoimmune Diabetes in Mice
Muralidharan C, Huang F, Enriquez JR, Wang JE, Nelson JB, Nargis T, May SC, Chakraborty A, Figatner KT, Navitskaya S, Anderson CM, Calvo V, Surguladze D, Mulvihill MJ, Yi X, Sarkar S, Oakes SA, Webb-Robertson BM, Sims EK, [...] Mirmira RG
bioRxiv, 06 Oct 2023
Cited by: 0 articles | PPR: PPR738089
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Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis
Sarkar S, Deiter C, Kyle JE, Guney MA, Sarbaugh D, Yin R, Li X, Cui Y, Ramos-Rodriguez M, Nicora CD, Syed F, Juan-Mateu J, Muralidharan C, Pasquali L, Evans-Molina C, Eizirik DL, Webb-Robertson BM, Burnum-Johnson K, Orr G, [...] Nakayasu E
Research Square, 17 Aug 2023
Cited by: 0 articles | PPR: PPR711647
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The Polyamine-Hypusine Circuit Controls an Oncogenic Translational Program Essential for Malignant Conversion in MYC-Driven Lymphoma.
Nakanishi S, Li J, Berglund AE, Kim Y, Zhang Y, Zhang L, Yang C, Song J, Mirmira RG, Cleveland JL
Blood Cancer Discov, 4(4):294-317, 01 Jul 2023
Cited by: 3 articles | PMID: 37070973 | PMCID: PMC10320645
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Non-Alcoholic Fatty Liver Disease: Translating Disease Mechanisms into Therapeutics Using Animal Models.
Basha A, May SC, Anderson RM, Samala N, Mirmira RG
Int J Mol Sci, 24(12):9996, 10 Jun 2023
Cited by: 2 articles | PMID: 37373143 | PMCID: PMC10298283
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