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Search life-sciences literature (45,100,050 articles, preprints and more)

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Genomic profiling of circulating tumor DNA for childhood cancers.
Lei S, Jia S, Takalkar S, Chang TC, Ma X, Szlachta K, Xu K, Cheng Z, Hui Y, Koo SC, Mead PE, Gao Q, Kumar P, Bailey CP, Sunny J, Pappo AS, Federico SM, Robinson GW, Gajjar A, [...] Mullighan CG
Leukemia, 10 Nov 2024
Cited by: 0 articles | PMID: 39523434
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IKAROS facilitates antigen escape in the face of CD19- and CD22-targeted therapies for B-cell acute lymphoblastic leukemia
Domizi P, Sarno J, Jager A, Merchant M, Pacheco KZB, Yamada-Hunter SA, Rotiroti MC, Liu Y, Baskar R, Reynolds WD, Sworder BJ, Sahaf B, Bendall SC, Mullighan CG, Alizadeh AA, Leahy AB, Myers RM, Yates B, Wang H, [...] Davis KL
bioRxiv, 03 Nov 2024
Cited by: 0 articles | PPR: PPR934750
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MLL oncoprotein levels influence leukemia lineage identities.
Janssens DH, Duran M, Otto DJ, Wu W, Xu Y, Kirkey D, Mullighan CG, Yi JS, Meshinchi S, Sarthy JF, Ahmad K, Henikoff S
Nat Commun, 15(1):9341, 29 Oct 2024
Cited by: 1 article | PMID: 39472576 | PMCID: PMC11522475
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Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk.
Kimura S, Park CS, Montefiori LE, Iacobucci I, Pölönen P, Gao Q, Arnold ED, Attarbaschi A, Brown A, Buldini B, Caldwell KJ, Chang Y, Chen C, Cheng C, Cheng Z, Choi J, Conter V, Crews KR, de Groot-Kruseman HA, [...] Mullighan CG
Cancer Discov, 14(10):1838-1859, 01 Oct 2024
Cited by: 0 articles | PMID: 38916500
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Classification and risk stratification in T-lineage acute lymphoblastic leukemia.
Pölönen P, Mullighan CG, Teachey DT
Blood, blood.2023022920, 02 Oct 2024
Cited by: 0 articles | PMID: 39357057
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Outcomes in patients with ETV6::RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies.
Purvis K, Zhou Y, Karol SE, Rubnitz JE, Ribeiro RC, Lee SH, Yang JJ, Bowman WP, Wang L, Dixon SB, Roberts KG, Gao Q, Cheng C, Mullighan CG, Jeha S, Pui CH, Inaba H
Blood, blood.2024024936, 24 Sep 2024
Cited by: 0 articles | PMID: 39316653
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Genomic Determinants of Outcome in Acute Lymphoblastic Leukemia.
Chang TC, Chen W, Qu C, Cheng Z, Hedges D, Elsayed A, Pounds SB, Shago M, Rabin KR, Raetz EA, Devidas M, Cheng C, Angiolillo A, Baviskar P, Borowitz M, Burke MJ, Carroll A, Carroll WL, Chen IM, [...] Loh ML
J Clin Oncol, 42(29):3491-3503, 09 Aug 2024
Cited by: 0 articles | PMID: 39121442 | PMCID: PMC11458106
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Bootstrap Evaluation of Association Matrices (BEAM) for Integrating Multiple Omics Profiles with Multiple Outcomes
Seffernick AE, Cao X, Cheng C, Yang W, Autry RJ, Yang JJ, Pui C, Teachey DT, Lamba JK, Mullighan CG, Pounds SB
bioRxiv, 03 Aug 2024
Cited by: 0 articles | PPR: PPR890466
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The genomic basis of childhood T-lineage acute lymphoblastic leukaemia.
Pölönen P, Di Giacomo D, Seffernick AE, Elsayed A, Kimura S, Benini F, Montefiori LE, Wood BL, Xu J, Chen C, Cheng Z, Newman H, Myers J, Iacobucci I, Li E, Sussman J, Hedges D, Hui Y, Diorio C, [...] Teachey DT
Nature, 632(8027):1082-1091, 14 Aug 2024
Cited by: 2 articles | PMID: 39143224
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Impact of Age on Pharmacogenomics and Treatment Outcomes of B-Cell Acute Lymphoblastic Leukemia.
Yoshimura S, Li Z, Gocho Y, Yang W, Crews KR, Lee SHR, Roberts KG, Mullighan CG, Relling MV, Yu J, Yeoh AEJ, Loh ML, Saygin C, Litzow MR, Jeha S, Karol SE, Inaba H, Pui CH, Konopleva M, [...] Yang JJ
J Clin Oncol, 42(29):3478-3490, 05 Aug 2024
Cited by: 0 articles | PMID: 39102629
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Blinatumomab for MRD-Negative Acute Lymphoblastic Leukemia in Adults.
Litzow MR, Sun Z, Mattison RJ, Paietta EM, Roberts KG, Zhang Y, Racevskis J, Lazarus HM, Rowe JM, Arber DA, Wieduwilt MJ, Liedtke M, Bergeron J, Wood BL, Zhao Y, Wu G, Chang TC, Zhang W, Pratz KW, [...] Tallman MS
N Engl J Med, 391(4):320-333, 01 Jul 2024
Cited by: 4 articles | PMID: 39047240
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Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL.
Zhao Y, Short NJ, Kantarjian HM, Chang TC, Ghate PS, Qu C, Macaron W, Jain N, Thakral B, Phillips AH, Khoury J, Garcia-Manero G, Zhang W, Fan Y, Yang H, Garris RS, Nasr LF, Kriwacki RW, Roberts KG, [...] Mullighan CG
Blood, 144(1):61-73, 01 Jul 2024
Cited by: 1 article | PMID: 38551807
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A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia.
Klein K, Kollmann S, Hiesinger A, List J, Kendler J, Klampfl T, Rhandawa M, Trifinopoulos J, Maurer B, Grausenburger R, Betram CA, Moriggl R, Rülicke T, Mullighan CG, Witalisz-Siepracka A, Walter W, Hoermann G, Sexl V, Gotthardt D
Blood, 143(24):2474-2489, 01 Jun 2024
Cited by: 0 articles | PMID: 38498036
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Conserved epigenetic hallmarks of T cell aging during immunity and malignancy.
Mi T, Soerens AG, Alli S, Kang TG, Vasandan AB, Wang Z, Vezys V, Kimura S, Iacobucci I, Baylin SB, Jones PA, Hiner C, Mueller A, Goldstein H, Mullighan CG, Zebley CC, Masopust D, Youngblood B
Nat Aging, 4(8):1053-1063, 12 Jun 2024
Cited by: 1 article | PMID: 38867059 | PMCID: PMC11333289
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Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms.
Sumaria N, Fiala GJ, Inácio D, Curado-Avelar M, Cachucho A, Pinheiro R, Wiesheu R, Kimura S, Courtois L, Blankenhaus B, Darrigues J, Suske T, Almeida ARM, Minguet S, Asnafi V, Lhermitte L, Mullighan CG, Coffelt SB, Moriggl R, [...] Silva-Santos B
Nat Immunol, 25(7):1207-1217, 27 May 2024
Cited by: 1 article | PMID: 38802512 | PMCID: PMC11224017
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Acute lymphoblastic leukaemia.
Pagliaro L, Chen SJ, Herranz D, Mecucci C, Harrison CJ, Mullighan CG, Zhang M, Chen Z, Boissel N, Winter SS, Roti G
Nat Rev Dis Primers, 10(1):41, 13 Jun 2024
Cited by: 3 articles | PMID: 38871740
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CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia.
Cardoso BA, Duque M, Gírio A, Fragoso R, Oliveira ML, Allen JR, Martins LR, Correia NC, Silveira AB, Veloso A, Kimura S, Demoen L, Matthijssens F, Jeha S, Cheng C, Pui CH, Grosso AR, Neto JL, De Almeida SF, [...] Barata JT
Haematologica, 109(6):1713-1725, 01 Jun 2024
Cited by: 1 article | PMID: 38058200
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Proximally biased V(D)J recombination in the clonal evolution of IGH alleles in KMT2A::AFF1 BCP-ALL of all age classes.
Müller H, Dicker F, Bär C, Walter W, Hutter S, Nadarajah N, Meggendorfer M, Gao Q, Iacobucci I, Mullighan CG, Kern W, Haferlach T, Haferlach C
Hemasphere, 8(4):e71, 22 Apr 2024
Cited by: 0 articles | PMID: 38650597 | PMCID: PMC11033919
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Association of leukemic molecular profile with efficacy of inotuzumab ozogamicin in adults with relapsed/refractory ALL.
Zhao Y, Laird AD, Roberts KG, Yafawi R, Kantarjian H, DeAngelo DJ, Stelljes M, Liedtke M, Stock W, Gökbuget N, O'Brien S, Jabbour E, Cassaday RD, Loyd MR, Olsen S, Neale G, Liu X, Vandendries E, Advani A, Mullighan CG
Blood Adv, 8(12):3226-3236, 01 Jun 2024
Cited by: 0 articles | PMID: 38607410 | PMCID: PMC11225676
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Enhanced Risk Stratification for Children and Young Adults with B-Cell Acute Lymphoblastic Leukemia: A Children's Oncology Group Report.
DelRocco NJ, Loh ML, Borowitz MJ, Gupta S, Rabin KR, Zweidler-McKay P, Maloney KW, Mattano LA, Larsen E, Angiolillo A, Schore RJ, Burke MJ, Salzer WL, Wood BL, Carroll AJ, Heerema NA, Reshmi SC, Gastier-Foster JM, Harvey R, [...] Kairalla JA
Leukemia, 38(4):720-728, 15 Feb 2024
Cited by: 3 articles | PMID: 38360863 | PMCID: PMC10997503
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Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.
Nishiguchi G, Mascibroda LG, Young SM, Caine EA, Abdelhamed S, Kooijman JJ, Miller DJ, Das S, McGowan K, Mayasundari A, Shi Z, Barajas JM, Hiltenbrand R, Aggarwal A, Chang Y, Mishra V, Narina S, Thomas M, Loughran AJ, [...] Rankovic Z
Nat Commun, 15(1):482, 16 Jan 2024
Cited by: 4 articles | PMID: 38228616 | PMCID: PMC10791743
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Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AML
Zeng AG, Iacobucci I, Shah S, Mitchell A, Wong G, Bansal S, Chen D, Gao Q, Kim H, Kennedy JA, Arruda A, Minden MD, Haferlach T, Mullighan CG, Dick JE
bioRxiv, 27 Dec 2023
Cited by: 0 articles | PPR: PPR779460
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Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression.
Molina O, Ortega-Sabater C, Thampi N, Fernández-Fuentes N, Guerrero-Murillo M, Martínez-Moreno A, Vinyoles M, Velasco-Hernández T, Bueno C, Trincado JL, Granada I, Campos D, Giménez C, Boer JM, den Boer ML, Calvo GF, Camós M, Fuster JL, Velasco P, [...] Menéndez P
EMBO Mol Med, 16(1):64-92, 15 Dec 2023
Cited by: 1 article | PMID: 38177531 | PMCID: PMC10897411
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SINGLE CELL DISSECTION OF DEVELOPMENTAL ORIGINS AND TRANSCRIPTIONAL HETEROGENEITY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Iacobucci I, Zeng AG, Gao Q, Garcia-Prat L, Baviskar P, Shah S, Murison A, Voisin V, Chan-Seng-Yue M, Cheng C, Qu C, Bailey C, Lear M, Witkowski MT, Zhou X, Peraza AZ, Gangwani K, Advani AS, Luger SM, [...] Mullighan CG
bioRxiv, 09 Dec 2023
Cited by: 0 articles | PPR: PPR771693
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Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL
Zhao Y, Short NJ, Kantarjian HM, Chang T, Ghate PS, Qu C, Macaron W, Jain N, Thakral B, Phillips AH, Khoury J, Garcia-Manero G, Zhang W, Fan Y, Yang H, Garris RS, Nasr LF, Kriwacki RW, Roberts KG, [...] Mullighan CG
medRxiv, 09 Dec 2023
Cited by: 0 articles | PPR: PPR771633
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1-25 of 362 results

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Search life-sciences literature (45,100,050 articles, preprints and more)

Search results

Genomic profiling of circulating tumor DNA for childhood cancers.

IKAROS facilitates antigen escape in the face of CD19- and CD22-targeted therapies for B-cell acute lymphoblastic leukemia

MLL oncoprotein levels influence leukemia lineage identities.

Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk.

Classification and risk stratification in T-lineage acute lymphoblastic leukemia.

Outcomes in patients with ETV6::RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies.

Genomic Determinants of Outcome in Acute Lymphoblastic Leukemia.

Bootstrap Evaluation of Association Matrices (BEAM) for Integrating Multiple Omics Profiles with Multiple Outcomes

The genomic basis of childhood T-lineage acute lymphoblastic leukaemia.

Impact of Age on Pharmacogenomics and Treatment Outcomes of B-Cell Acute Lymphoblastic Leukemia.

Blinatumomab for MRD-Negative Acute Lymphoblastic Leukemia in Adults.

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL.

A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia.

Conserved epigenetic hallmarks of T cell aging during immunity and malignancy.

Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms.

Acute lymphoblastic leukaemia.

CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia.

Proximally biased V(D)J recombination in the clonal evolution of IGH alleles in KMT2A::AFF1 BCP-ALL of all age classes.

Association of leukemic molecular profile with efficacy of inotuzumab ozogamicin in adults with relapsed/refractory ALL.

Enhanced Risk Stratification for Children and Young Adults with B-Cell Acute Lymphoblastic Leukemia: A Children's Oncology Group Report.

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.

Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AML

Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression.

SINGLE CELL DISSECTION OF DEVELOPMENTAL ORIGINS AND TRANSCRIPTIONAL HETEROGENEITY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

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