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Pan African Vivax and Ovale Network (PAVON) Malaria Diagnostic Competency Training: Offering Training Opportunities to Impact Malaria Elimination Strategies in Sub-Saharan Africa
Diarra A, Ayivase J, Mompati DG, Soulama I, CISSE M, Duah-Quashie NO, Gyan B, Dongdem AZ, Takramah WK, Ababio GK, Oeuvray C, Mulry J, Greco B, Reinhard-Rupp J, Quaye IK
Preprints.org, 30 Oct 2024
Cited by: 0 articles | PPR: PPR932869
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Towards clinically relevant dose ratios for Cabamiquine and Pyronaridine combination using P. falciparum field isolate data.
Maiga M, Dembele L, Courlet P, Khandelwal A, Dara A, Sogore F, Diakité O, Maiga FO, Dao F, Sissoko S, Barre Y, Goita S, Diakite M, Diakite SAS, Djimde AA, Oeuvray C, Spangenberg T, Wicha SG, Demarta-Gatsi C
Nat Commun, 15(1):7659, 03 Sep 2024
Cited by: 0 articles | PMID: 39227370 | PMCID: PMC11372057
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Absence of developmental and reproductive toxicity in rats, rabbits, and zebrafish embryos exposed to antimalarial drug cabamiquine.
Gado A, Hewitt P, Ballard P, Tornesi B, Baeurle THH, Oeuvray C, Spangenberg T, Demarta-Gatsi C
Birth Defects Res, 116(8):e2389, 01 Aug 2024
Cited by: 0 articles | PMID: 39192608
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Gut microbiota alterations are associated with phenotype and genotype in familial Mediterranean fever.
Delplanque M, Benech N, Rolhion N, Oeuvray C, Straube M, Galbert C, Brot L, Henry T, Jamilloux Y, Savey L, Grateau G, Sokol H, Georgin-Lavialle S
Rheumatology (Oxford), 63(4):1039-1048, 01 Apr 2024
Cited by: 0 articles | PMID: 37402619
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Insulation of ribosomal promoter activity by Fis, H-NS or a divergent promoter within the packed E. coli genome.
Brambilla E, Yousuf M, Zhang Q, Mbemba G, Oeuvray C, Mektepbayeva D, Olliver A, Lagomarsino MC, Sclavi B
bioRxiv, 28 Mar 2024
Cited by: 0 articles | PPR: PPR828850
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Semi-mechanistic population pharmacokinetic/pharmacodynamic modeling of a Plasmodium elongation factor 2 inhibitor cabamiquine for prevention and cure of malaria.
Courlet P, Wilkins JJ, Oeuvray C, Gao W, Khandelwal A
Antimicrob Agents Chemother, 67(12):e0089123, 15 Nov 2023
Cited by: 2 articles | PMID: 37966273 | PMCID: PMC10720512
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Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine.
Stadler E, Maiga M, Friedrich L, Thathy V, Demarta-Gatsi C, Dara A, Sogore F, Striepen J, Oeuvray C, Djimdé AA, Lee MCS, Dembélé L, Fidock DA, Khoury DS, Spangenberg T
Nat Commun, 14(1):5447, 06 Sep 2023
Cited by: 0 articles | PMID: 37673924 | PMCID: PMC10482846
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Propensity of selecting mutant parasites for the antimalarial drug cabamiquine.
Stadler E, Maiga M, Friedrich L, Thathy V, Demarta-Gatsi C, Dara A, Sogore F, Striepen J, Oeuvray C, Djimdé AA, Lee MCS, Dembélé L, Fidock DA, Khoury DS, Spangenberg T
Nat Commun, 14(1):5205, 25 Aug 2023
Cited by: 7 articles | PMID: 37626093 | PMCID: PMC10457284
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Malaria Elimination in Africa: Rethinking Strategies for Plasmodium vivax and Lessons from Botswana.
Quaye IK, Aleksenko L, Paganotti GM, Peloewetse E, Haiyambo DH, Ntebela D, Oeuvray C, Greco B, The Pavon Consortium
Trop Med Infect Dis, 8(8):392, 31 Jul 2023
Cited by: 1 article | PMID: 37624330 | PMCID: PMC10458071
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The delayed bloodstream clearance of Plasmodium falciparum parasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts.
Parkyn Schneider M, Looker O, Rebelo M, Khoury DS, Dixon MWA, Oeuvray C, Crabb BS, McCarthy J, Gilson PR
Front Cell Infect Microbiol, 13:1211613, 29 Jun 2023
Cited by: 2 articles | PMID: 37457953
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Evaluation of a multiphasic parasite clearance profile after treatment of experimental human infection with the investigational anti-malarial M5717 using segmented mixed effect models.
Yin X, Li Y, Bagchus W, Yalkinoglu Ö, Bezuidenhout D, Tappert A, McCarthy J, Marquart L, Oeuvray C
Malar J, 22(1):199, 28 Jun 2023
Cited by: 1 article | PMID: 37381013 | PMCID: PMC10303793
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Malaria Elimination in Africa: Rethinking Strategies for P. vivax and Lessons From Botswana
Quaye IK, Aleksenko L, Paganotti GM, Peloewetse E, Haiyambo DH, Ntebela D, Oeuvray C, Greco B
Preprints.org, 26 Jun 2023
Cited by: 0 articles | PPR: PPR681169
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Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands.
van der Plas JL, Kuiper VP, Bagchus WM, Bödding M, Yalkinoglu Ö, Tappert A, Seitzinger A, Spangenberg T, Bezuidenhout D, Wilkins J, Oeuvray C, Dhingra SK, Thathy V, Fidock DA, Smidt LCA, Roozen GVT, Koopman JPR, Lamers OAC, Sijtsma J, [...] Khandelwal A
Lancet Infect Dis, 23(10):1164-1174, 03 Jul 2023
Cited by: 9 articles | PMID: 37414066
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The delayed bloodstream clearance ofPlasmodium falciparumparasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts
Schneider MP, Looker O, Rebelo M, Khoury DK, Dixon MW, Oeuvray C, Crabb BS, McCarthy J, Gilson PR
bioRxiv, 24 Apr 2023
Cited by: 0 articles | PPR: PPR650266
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Human CD4+CD8α+ Tregs induced by Faecalibacterium prausnitzii protect against intestinal inflammation.
Touch S, Godefroy E, Rolhion N, Danne C, Oeuvray C, Straube M, Galbert C, Brot L, Alonso Salgueiro I, Chadi S, Ledent T, Chatel JM, Langella P, Jotereau F, Altare F, Sokol H
JCI Insight, 7(12):e154722, 22 Jun 2022
Cited by: 20 articles | PMID: 35536673 | PMCID: PMC9309064
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Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases.
Michaudel C, Danne C, Agus A, Magniez A, Aucouturier A, Spatz M, Lefevre A, Kirchgesner J, Rolhion N, Wang Y, Lavelle A, Galbert C, Da Costa G, Poirier M, Lapière A, Planchais J, Nádvorník P, Illes P, Oeuvray C, [...] Sokol H
Gut, 72(7):1296-1307, 21 Oct 2022
Cited by: 50 articles | PMID: 36270778 | PMCID: PMC10314090
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Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside.
Khandelwal A, Arez F, Alves PM, Badolo L, Brito C, Fischli C, Fontinha D, Oeuvray C, Prudêncio M, Rottmann M, Wilkins J, Yalkinoglu Ö, Bagchus WM, Spangenberg T
Malar J, 21(1):151, 15 May 2022
Cited by: 4 articles | PMID: 35570264 | PMCID: PMC9107587
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CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival.
Danne C, Michaudel C, Skerniskyte J, Planchais J, Magniez A, Agus A, Michel ML, Lamas B, Da Costa G, Spatz M, Oeuvray C, Galbert C, Poirier M, Wang Y, Lapière A, Rolhion N, Ledent T, Pionneau C, Chardonnet S, [...] Sokol H
Gut, 72(6):1081-1092, 27 Sep 2022
Cited by: 14 articles | PMID: 36167663
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An innovative study design with intermittent dosing to generate a GLP-regulatory package in preclinical species for long lasting molecule M5717, inhibitor of Plasmodium eukaryotic translation elongation factor 2.
Hewitt P, Abla N, Lignet F, Oeuvray C, Bagchus W, Bebrevska L
Toxicol Appl Pharmacol, 443:116006, 31 Mar 2022
Cited by: 0 articles | PMID: 35367236
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Human CD4⁺/CD8α⁺ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation
Touch S, Godefroy E, Rolhion N, Danne C, Oeuvray C, Straube M, Galbert C, Brot L, Salgueiro IA, Chadi S, Ledent T, Chatel J, Langella P, Jotereau F, Altare F, Sokol H
bioRxiv, 23 Mar 2022
Cited by: 0 articles | PPR: PPR472033
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CARD9 in Neutrophils Protects from Colitis and Controls Mitochondrial Metabolism and Cell Survival
Danne C, Michaudel C, Skerniskyte J, Planchais J, Magniez A, Agus A, Michel M, Lamas B, Da-Costa G, Spatz M, Oeuvray C, Galbert C, Poirier M, Wang Y, Lapiere A, Rolhion N, Ledent T, Pionneau C, Chardonnet S, [...] Sokol H
bioRxiv, 15 Jan 2022
Cited by: 0 articles | PPR: PPR443271
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Butyrate acts through HDAC inhibition to enhance aryl hydrocarbon receptor activation by gut microbiota-derived ligands.
Modoux M, Rolhion N, Lefevre JH, Oeuvray C, Nádvorník P, Illes P, Emond P, Parc Y, Mani S, Dvorak Z, Sokol H
Gut Microbes, 14(1):2105637, 01 Jan 2022
Cited by: 26 articles | PMID: 35895845 | PMCID: PMC9336500
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Reproducibility of malaria sporozoite challenge model in humans for evaluating efficacy of vaccines and drugs: a systematic review.
Shibeshi W, Bagchus W, Yalkinoglu Ö, Tappert A, Engidawork E, Oeuvray C
BMC Infect Dis, 21(1):1274, 20 Dec 2021
Cited by: 3 articles | PMID: 34930178 | PMCID: PMC8686662
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Fecal microbiota and bile acids in IBD patients undergoing screening for colorectal cancer.
Lavelle A, Nancey S, Reimund JM, Laharie D, Marteau P, Treton X, Allez M, Roblin X, Malamut G, Oeuvray C, Rolhion N, Dray X, Rainteau D, Lamaziere A, Gauliard E, Kirchgesner J, Beaugerie L, Seksik P, Peyrin-Biroulet L, Sokol H
Gut Microbes, 14(1):2078620, 01 Jan 2022
Cited by: 18 articles | PMID: 35638103 | PMCID: PMC9176255
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Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study and volunteer infection study.
McCarthy JS, Yalkinoglu Ö, Odedra A, Webster R, Oeuvray C, Tappert A, Bezuidenhout D, Giddins MJ, Dhingra SK, Fidock DA, Marquart L, Webb L, Yin X, Khandelwal A, Bagchus WM
Lancet Infect Dis, 21(12):1713-1724, 26 Oct 2021
Cited by: 29 articles | PMID: 34715032 | PMCID: PMC8612936
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1-25 of 50 results

1 2

Search life-sciences literature (45,100,050 articles, preprints and more)

Search results

Pan African Vivax and Ovale Network (PAVON) Malaria Diagnostic Competency Training: Offering Training Opportunities to Impact Malaria Elimination Strategies in Sub-Saharan Africa

Towards clinically relevant dose ratios for Cabamiquine and Pyronaridine combination using P. falciparum field isolate data.

Absence of developmental and reproductive toxicity in rats, rabbits, and zebrafish embryos exposed to antimalarial drug cabamiquine.

Gut microbiota alterations are associated with phenotype and genotype in familial Mediterranean fever.

Insulation of ribosomal promoter activity by Fis, H-NS or a divergent promoter within the packed E. coli genome.

Semi-mechanistic population pharmacokinetic/pharmacodynamic modeling of a Plasmodium elongation factor 2 inhibitor cabamiquine for prevention and cure of malaria.

Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine.

Propensity of selecting mutant parasites for the antimalarial drug cabamiquine.

Malaria Elimination in Africa: Rethinking Strategies for Plasmodium vivax and Lessons from Botswana.

The delayed bloodstream clearance of Plasmodium falciparum parasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts.

Evaluation of a multiphasic parasite clearance profile after treatment of experimental human infection with the investigational anti-malarial M5717 using segmented mixed effect models.

Malaria Elimination in Africa: Rethinking Strategies for P. vivax and Lessons From Botswana

Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands.

The delayed bloodstream clearance ofPlasmodium falciparumparasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts

Human CD4+CD8α+ Tregs induced by Faecalibacterium prausnitzii protect against intestinal inflammation.

Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases.

Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside.

CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival.

An innovative study design with intermittent dosing to generate a GLP-regulatory package in preclinical species for long lasting molecule M5717, inhibitor of Plasmodium eukaryotic translation elongation factor 2.

Human CD4⁺/CD8α⁺ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation

CARD9 in Neutrophils Protects from Colitis and Controls Mitochondrial Metabolism and Cell Survival

Butyrate acts through HDAC inhibition to enhance aryl hydrocarbon receptor activation by gut microbiota-derived ligands.

Reproducibility of malaria sporozoite challenge model in humans for evaluating efficacy of vaccines and drugs: a systematic review.

Fecal microbiota and bile acids in IBD patients undergoing screening for colorectal cancer.

Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study and volunteer infection study.

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