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Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry.
Andreozzi G, Corvino A, Severino B, Magli E, Perissutti E, Frecentese F, Santagada V, Caliendo G, Fiorino F
Pharmaceuticals (Basel), 17(10):1320, 02 Oct 2024
Cited by: 0 articles | PMID: 39458961 | PMCID: PMC11510360
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A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation.
Corvino A, Granato E, Scognamiglio A, Fiorino F, Frecentese F, Magli E, Perissutti E, Santagada V, Cirino G, Cerqua I, Pavese R, Petti A, Pavese F, Petti F, Roviezzo F, Severino B, Caliendo G
Molecules, 29(18):4514, 23 Sep 2024
Cited by: 0 articles | PMID: 39339509 | PMCID: PMC11434587
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Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry
Andreozzi G, Corvino A, Severino B, Magli E, Perissutti E, Frecentese F, Santagada V, Caliendo G, Fiorino F
Preprints.org, 19 Jul 2024
Cited by: 0 articles | PPR: PPR885723
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Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice.
Corvino A, Caliendo G, Fiorino F, Frecentese F, Valsecchi V, Lombardi G, Anzilotti S, Andreozzi G, Scognamiglio A, Sparaco R, Perissutti E, Severino B, Gargiulo M, Santagada V, Pignataro G
ACS Pharmacol Transl Sci, 7(7):1996-2005, 22 Jun 2024
Cited by: 0 articles | PMID: 39022351
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Pills of Multi-Target H₂S Donating Molecules for Complex Diseases.
Corvino A, Scognamiglio A, Fiorino F, Perissutti E, Santagada V, Caliendo G, Severino B
Int J Mol Sci, 25(13):7014, 27 Jun 2024
Cited by: 1 article | PMID: 39000122
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Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength.
Scognamiglio A, Cerqua I, Citi V, Martelli A, Spezzini J, Calderone V, Rimoli MG, Sodano F, Caliendo G, Santagada V, Fiorino F, Frecentese F, Perissutti E, Magli E, Simonelli M, Corvino A, Roviezzo F, Severino B
Eur J Med Chem, 275:116636, 28 Jun 2024
Cited by: 0 articles | PMID: 38944936
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3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers' Absolute Configuration.
Sparaco R, Cinque P, Scognamiglio A, Corvino A, Caliendo G, Fiorino F, Magli E, Perissutti E, Santagada V, Severino B, Luciano P, Casertano M, Aiello A, Martins Viegas GY, De Nucci G, Frecentese F
Molecules, 29(7):1598, 03 Apr 2024
Cited by: 1 article | PMID: 38611877 | PMCID: PMC11013601
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Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring.
Andreozzi G, Ambrosio MR, Magli E, Maneli G, Severino B, Corvino A, Sparaco R, Perissutti E, Frecentese F, Santagada V, Leśniak A, Bujalska-Zadrożny M, Caliendo G, Formisano P, Fiorino F
Pharmaceuticals (Basel), 16(10):1483, 18 Oct 2023
Cited by: 1 article | PMID: 37895954 | PMCID: PMC10609883
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Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma.
Cerqua I, Granato E, Corvino A, Severino B, D'Avino D, Simonelli M, Perissutti E, Scognamiglio A, Mirra D, D'Agostino B, Caliendo G, Rossi A, Cirino G, Motta CM, Roviezzo F
Front Pharmacol, 14:1266934, 12 Oct 2023
Cited by: 2 articles | PMID: 37900172 | PMCID: PMC10602694
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Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol.
Sparaco R, Scognamiglio A, Corvino A, Caliendo G, Fiorino F, Magli E, Perissutti E, Santagada V, Severino B, Luciano P, Casertano M, Aiello A, De Nucci G, Frecentese F
Molecules, 28(1):57, 21 Dec 2022
Cited by: 2 articles | PMID: 36615252 | PMCID: PMC9822233
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Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H₂S Donors.
Sparaco R, Citi V, Magli E, Martelli A, Piragine E, Calderone V, Andreozzi G, Perissutti E, Frecentese F, Santagada V, Caliendo G, Severino B, Corvino A, Fiorino F
Int J Mol Sci, 23(22):13804, 09 Nov 2022
Cited by: 3 articles | PMID: 36430281 | PMCID: PMC9695456
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Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus.
Sparaco R, Kędzierska E, Kaczor AA, Bielenica A, Magli E, Severino B, Corvino A, Gibuła-Tarłowska E, Kotlińska JH, Andreozzi G, Luciano P, Perissutti E, Frecentese F, Casertano M, Leśniak A, Bujalska-Zadrożny M, Oziębło M, Capasso R, Santagada V, [...] Fiorino F
Molecules, 27(19):6492, 01 Oct 2022
Cited by: 2 articles | PMID: 36235029 | PMCID: PMC9572521
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H₂S Donors and Their Use in Medicinal Chemistry.
Magli E, Perissutti E, Santagada V, Caliendo G, Corvino A, Esposito G, Esposito G, Fiorino F, Migliaccio M, Scognamiglio A, Severino B, Sparaco R, Frecentese F
Biomolecules, 11(12):1899, 18 Dec 2021
Cited by: 26 articles | PMID: 34944543 | PMCID: PMC8699746
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New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na⁺/Ca²⁺ Exchanger Isoforms.
Magli E, Fattorusso C, Persico M, Corvino A, Esposito G, Fiorino F, Luciano P, Perissutti E, Santagada V, Severino B, Tedeschi V, Pannaccione A, Pignataro G, Caliendo G, Annunziato L, Secondo A, Frecentese F
J Med Chem, 64(24):17901-17919, 30 Nov 2021
Cited by: 5 articles | PMID: 34845907 | PMCID: PMC8713167
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Antagonizing S1P₃ Receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis.
Corvino A, Cerqua I, Lo Bianco A, Caliendo G, Fiorino F, Frecentese F, Magli E, Morelli E, Perissutti E, Santagada V, Cirino G, Granato E, Roviezzo F, Puliti E, Bernacchioni C, Lavecchia A, Donati C, Severino B
Int J Mol Sci, 22(16):8861, 17 Aug 2021
Cited by: 0 articles | PMID: 34445567 | PMCID: PMC8396189
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Hybrids between H₂S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells.
Giordano F, Corvino A, Scognamiglio A, Citi V, Gorica E, Fattorusso C, Persico M, Caliendo G, Fiorino F, Magli E, Perissutti E, Santagada V, Severino B, Pavese RC, Petti F, Martelli A, Calderone V, Frecentese F
Eur J Med Chem, 221:113517, 05 May 2021
Cited by: 8 articles | PMID: 33984803
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H₂S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma.
Corvino A, Citi V, Fiorino F, Frecentese F, Magli E, Perissutti E, Santagada V, Calderone V, Martelli A, Gorica E, Brogi S, Colombo FF, Capello CN, Araujo Ferreira HH, Rimoli MG, Sodano F, Rolando B, Pavese F, Petti A, [...] Severino B
J Adv Res, 35:267-277, 20 May 2021
Cited by: 12 articles | PMID: 35024201 | PMCID: PMC8721254
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Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands.
Magli E, Kędzierska E, Kaczor AA, Bielenica A, Severino B, Gibuła-Tarłowska E, Kotlińska JH, Corvino A, Sparaco R, Esposito G, Albrizio S, Perissutti E, Frecentese F, Leśniak A, Bujalska-Zadrożny M, Struga M, Capasso R, Santagada V, Caliendo G, Fiorino F
Arch Pharm (Weinheim), 354(5):e2000414, 05 Feb 2021
Cited by: 7 articles | PMID: 33543794
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Trends in H₂S-Donors Chemistry and Their Effects in Cardiovascular Diseases.
Corvino A, Frecentese F, Magli E, Perissutti E, Santagada V, Scognamiglio A, Caliendo G, Fiorino F, Severino B
Antioxidants (Basel), 10(3):429, 11 Mar 2021
Cited by: 28 articles | PMID: 33799669 | PMCID: PMC8002049
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Structure-activity relationships study of isothiocyanates for H₂S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent.
Citi V, Corvino A, Fiorino F, Frecentese F, Magli E, Perissutti E, Santagada V, Brogi S, Flori L, Gorica E, Testai L, Martelli A, Calderone V, Caliendo G, Severino B
J Adv Res, 27:41-53, 03 Mar 2020
Cited by: 19 articles | PMID: 33318865 | PMCID: PMC7728584
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PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy).
Ferrante MC, Di Vaio P, Magli E, Frecentese F, Meli R, Caliendo G, Corvino A, Fiorino F, Giordano F, Monnolo A, Saccone I, Santagada V, Severino B, Calabria G, Manzo C, Perissutti E
Chemosphere, 244:125478, 27 Nov 2019
Cited by: 2 articles | PMID: 31812762
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New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation.
Magli E, Severino B, Corvino A, Perissutti E, Frecentese F, Saccone I, Giordano F, Castro M, Brea J, Loza MI, Santagada V, Caliendo G, Fiorino F
Med Chem, 16(4):517-530, 01 Jan 2020
Cited by: 0 articles | PMID: 31203804
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Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration.
Severino B, Corvino A, Fiorino F, Frecentese F, Perissutti E, Caliendo G, Santagada V, Magli E, Molinaro P, Pignataro G, Annunziato L, Antunes NJ, Rojas-Moscoso J, de Freitas NL, Mendes GD, De Nucci G
Front Pharmacol, 10:432, 25 Apr 2019
Cited by: 2 articles | PMID: 31073288 | PMCID: PMC6497007
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Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation.
Zaminelli T, Magli E, Frecentese F, Lescano CH, Campos R, Saccone I, Corvino A, Di Vaio P, Giordano F, Luciano P, Fiorino F, Perissutti E, Santagada V, Severino B, Caliendo G, De Nucci G
ChemistryOpen, 8(4):464-475, 08 Apr 2019
Cited by: 0 articles | PMID: 31008011 | PMCID: PMC6454219
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Synthesis, docking studies, and pharmacological evaluation of 5HT_2C ligands containing the N'-cyanoisonicotinamidine or N'-cyanopicolinamidine nucleus.
Magli E, Kędzierska E, Kaczor AA, Severino B, Corvino A, Perissutti E, Frecentese F, Saccone I, Massarelli P, Gibuła-Tarłowska E, Kotlińska JH, Santagada V, Caliendo G, Fiorino F
Arch Pharm (Weinheim), 352(5):e1800373, 26 Apr 2019
Cited by: 3 articles | PMID: 31025433
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1-25 of 97 results

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Search life-sciences literature (45,103,589 articles, preprints and more)

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Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry.

A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation.

Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry

Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice.

Pills of Multi-Target H₂S Donating Molecules for Complex Diseases.

Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength.

3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers' Absolute Configuration.

Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring.

Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma.

Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol.

Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H₂S Donors.

Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus.

H₂S Donors and Their Use in Medicinal Chemistry.

New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na⁺/Ca²⁺ Exchanger Isoforms.

Antagonizing S1P₃ Receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis.

Hybrids between H₂S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells.

H₂S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma.

Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands.

Trends in H₂S-Donors Chemistry and Their Effects in Cardiovascular Diseases.

Structure-activity relationships study of isothiocyanates for H₂S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent.

PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy).

New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation.

Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration.

Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation.

Synthesis, docking studies, and pharmacological evaluation of 5HT_2C ligands containing the N'-cyanoisonicotinamidine or N'-cyanopicolinamidine nucleus.

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