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Search life-sciences literature (45,104,145 articles, preprints and more)

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Randomized phase II trial of lymphodepletion plus adoptive cell transfer of tumor-infiltrating lymphocytes, with or without dendritic cell vaccination, in patients with metastatic melanoma.
Saberian C, Amaria RN, Najjar AM, Radvanyi LG, Haymaker CL, Forget MA, Bassett RL, Faria SC, Glitza IC, Alvarez E, Parshottam S, Prieto V, Lizée G, Wong MK, McQuade JL, Diab A, Yee C, Tawbi HA, Patel S, [...] Bernatchez C
J Immunother Cancer, 9(5):e002449, 01 May 2021
Cited by: 17 articles | PMID: 34021033 | PMCID: PMC8144048
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COVID-19: a pandemic experience that illuminates potential reforms to health research.
Kozlowski HN, Farkouh ME, Irwin MS, Radvanyi LG, Schimmer AD, Tabori U, Rosenblum ND
EMBO Mol Med, 12(11):e13278, 19 Oct 2020
Cited by: 4 articles | PMID: 32996267 | PMCID: PMC7536940
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Utilizing T-cell Activation Signals 1, 2, and 3 for Tumor-infiltrating Lymphocytes (TIL) Expansion: The Advantage Over the Sole Use of Interleukin-2 in Cutaneous and Uveal Melanoma.
Tavera RJ, Forget MA, Kim YU, Sakellariou-Thompson D, Creasy CA, Bhatta A, Fulbright OJ, Ramachandran R, Thorsen ST, Flores E, Wahl A, Gonzalez AM, Toth C, Wardell S, Mansaray R, Radvanyi LG, Gombos DS, Patel SP, Hwu P, [...] Haymaker C
J Immunother, 41(9):399-405, 01 Nov 2018
Cited by: 20 articles | PMID: 29757889 | PMCID: PMC6177302
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Targeting the cancer mutanome of breast cancer.
Radvanyi LG
Nat Med, 24(6):703-704, 01 Jun 2018
Cited by: 5 articles | PMID: 29867234
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Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response, Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome.
Forget MA, Haymaker C, Hess KR, Meng YJ, Creasy C, Karpinets T, Fulbright OJ, Roszik J, Woodman SE, Kim YU, Sakellariou-Thompson D, Bhatta A, Wahl A, Flores E, Thorsen ST, Tavera RJ, Ramachandran R, Gonzalez AM, Toth CL, [...] Bernatchez C
Clin Cancer Res, 24(18):4416-4428, 30 May 2018
Cited by: 60 articles | PMID: 29848573 | PMCID: PMC6139043
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Multifaceted Role of BTLA in the Control of CD8⁺ T-cell Fate after Antigen Encounter.
Ritthipichai K, Haymaker CL, Martinez M, Aschenbrenner A, Yi X, Zhang M, Kale C, Vence LM, Roszik J, Hailemichael Y, Overwijk WW, Varadarajan N, Nurieva R, Radvanyi LG, Hwu P, Bernatchez C
Clin Cancer Res, 23(20):6151-6164, 28 Jul 2017
Cited by: 37 articles | PMID: 28754817 | PMCID: PMC5748156
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Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function.
Lee YH, Martin-Orozco N, Zheng P, Li J, Zhang P, Tan H, Park HJ, Jeong M, Chang SH, Kim BS, Xiong W, Zang W, Guo L, Liu Y, Dong ZJ, Overwijk WW, Hwu P, Yi Q, Kwak L, [...] Dong C
Cell Res, 27(8):1034-1045, 07 Jul 2017
Cited by: 185 articles | PMID: 28685773 | PMCID: PMC5539354
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Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells.
An X, Sendra VG, Liadi I, Ramesh B, Romain G, Haymaker C, Martinez-Paniagua M, Lu Y, Radvanyi LG, Roysam B, Varadarajan N
PLoS One, 12(8):e0181904, 24 Aug 2017
Cited by: 28 articles | PMID: 28837583 | PMCID: PMC5570329
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4-1BB-Enhanced Expansion of CD8⁺ TIL from Triple-Negative Breast Cancer Unveils Mutation-Specific CD8⁺ T Cells.
Harao M, Forget MA, Roszik J, Gao H, Babiera GV, Krishnamurthy S, Chacon JA, Li S, Mittendorf EA, DeSnyder SM, Rockwood KF, Bernatchez C, Ueno NT, Radvanyi LG, Vence L, Haymaker C, Reuben JM
Cancer Immunol Res, 5(6):439-445, 04 May 2017
Cited by: 32 articles | PMID: 28473315 | PMCID: PMC5525328
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Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.
Roszik J, Haydu LE, Hess KR, Oba J, Joon AY, Siroy AE, Karpinets TV, Stingo FC, Baladandayuthapani V, Tetzlaff MT, Wargo JA, Chen K, Forget MA, Haymaker CL, Chen JQ, Meric-Bernstam F, Eterovic AK, Shaw KR, Mills GB, [...] Woodman SE
BMC Med, 14(1):168, 25 Oct 2016
Cited by: 80 articles | PMID: 27776519 | PMCID: PMC5078889
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Defective STAT1 activation associated with impaired IFN-γ production in NK and T lymphocytes from metastatic melanoma patients treated with IL-2.
Sim GC, Wu S, Jin L, Hwu P, Radvanyi LG
Oncotarget, 7(24):36074-36091, 01 Jun 2016
Cited by: 5 articles | PMID: 27153543 | PMCID: PMC5094984
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Tumor-Infiltrating Lymphocyte Therapy: Addressing Prevailing Questions.
Radvanyi LG
Cancer J, 21(6):450-464, 01 Nov 2015
Cited by: 31 articles | PMID: 26588676
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Intrathecal Administration of Tumor-Infiltrating Lymphocytes Is Well Tolerated in a Patient with Leptomeningeal Disease from Metastatic Melanoma: A Case Report.
Glitza IC, Haymaker C, Bernatchez C, Vence L, Rohlfs M, Richard J, Lacey C, Mansaray R, Fulbright OJ, Ramachandran R, Toth C, Wardell S, Patel SP, Woodman SE, Hwu WJ, Radvanyi LG, Davies MA, Papadopoulos NE, Hwu P
Cancer Immunol Res, 3(11):1201-1206, 27 Jul 2015
Cited by: 18 articles | PMID: 26216417 | PMCID: PMC4861225
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The beneficial effects of a gas-permeable flask for expansion of Tumor-Infiltrating lymphocytes as reflected in their mitochondrial function and respiration capacity.
Forget MA, Haymaker C, Dennison JB, Toth C, Maiti S, Fulbright OJ, Cooper LJ, Hwu P, Radvanyi LG, Bernatchez C
Oncoimmunology, 5(2):e1057386, 05 Jun 2015
Cited by: 9 articles | PMID: 27057427 | PMCID: PMC4801448
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BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties.
Haymaker CL, Wu RC, Ritthipichai K, Bernatchez C, Forget MA, Chen JQ, Liu H, Wang E, Marincola F, Hwu P, Radvanyi LG
Oncoimmunology, 4(8):e1014246, 16 Mar 2015
Cited by: 38 articles | PMID: 26405566 | PMCID: PMC4570103
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Peptide-based vaccination and induction of CD8+ T-cell responses against tumor antigens in breast cancer.
Harao M, Mittendorf EA, Radvanyi LG
BioDrugs, 29(1):15-30, 01 Feb 2015
Cited by: 13 articles | PMID: 25523015
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Activation and propagation of tumor-infiltrating lymphocytes on clinical-grade designer artificial antigen-presenting cells for adoptive immunotherapy of melanoma.
Forget MA, Malu S, Liu H, Toth C, Maiti S, Kale C, Haymaker C, Bernatchez C, Huls H, Wang E, Marincola FM, Hwu P, Cooper LJ, Radvanyi LG
J Immunother, 37(9):448-460, 01 Nov 2014
Cited by: 34 articles | PMID: 25304728 | PMCID: PMC4199393
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BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma.
Bradley SD, Chen Z, Melendez B, Talukder A, Khalili JS, Rodriguez-Cruz T, Liu S, Whittington M, Deng W, Li F, Bernatchez C, Radvanyi LG, Davies MA, Hwu P, Lizée G
Cancer Immunol Res, 3(6):602-609, 20 Mar 2015
Cited by: 98 articles | PMID: 25795007 | PMCID: PMC4457616
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An Antibody-based Blood Test Utilizing a Panel of Biomarkers as a New Method for Improved Breast Cancer Diagnosis.
Yahalom G, Weiss D, Novikov I, Bevers TB, Radvanyi LG, Liu M, Piura B, Iacobelli S, Sandri MT, Cassano E, Allweis TM, Bitterman A, Engelman P, Vence LM, Rosenberg MM
Biomark Cancer, 5:71-80, 19 Nov 2013
Cited by: 12 articles | PMID: 24324350 | PMCID: PMC3855201
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MUC1 glycopeptide epitopes predicted by computational glycomics.
Song W, Delyria ES, Chen J, Huang W, Lee JS, Mittendorf EA, Ibrahim N, Radvanyi LG, Li Y, Lu H, Xu H, Shi Y, Wang LX, Ross JA, Rodrigues SP, Almeida IC, Yang X, Qu J, Schocker NS, [...] Zhou D
Int J Oncol, 41(6):1977-1984, 27 Sep 2012
Cited by: 9 articles | PMID: 23023583 | PMCID: PMC3556481
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Prognostic value of the trichorhinophalangeal syndrome-1 (TRPS-1), a GATA family transcription factor, in early-stage breast cancer.
Chen JQ, Bao Y, Lee J, Murray JL, Litton JK, Xiao L, Zhou R, Wu Y, Shen XY, Zhang H, Sahin AA, Katz RL, Bondy ML, Berinstein NL, Hortobagyi GN, Radvanyi LG
Ann Oncol, 24(10):2534-2542, 31 May 2013
Cited by: 11 articles | PMID: 23729783 | PMCID: PMC3784330
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Continuous 4-1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy.
Chacon JA, Pilon-Thomas S, Sarnaik AA, Radvanyi LG
Oncoimmunology, 2(9):e25581, 03 Jul 2013
Cited by: 16 articles | PMID: 24319633 | PMCID: PMC3850170
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New insights on the role of CD8(+)CD57(+) T-cells in cancer.
Wu RC, Hwu P, Radvanyi LG
Oncoimmunology, 1(6):954-956, 01 Sep 2012
Cited by: 21 articles | PMID: 23162769 | PMCID: PMC3489757
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Impact of clinical and pathologic features on tumor-infiltrating lymphocyte expansion from surgically excised melanoma metastases for adoptive T-cell therapy.
Joseph RW, Peddareddigari VR, Liu P, Miller PW, Overwijk WW, Bekele NB, Ross MI, Lee JE, Gershenwald JE, Lucci A, Prieto VG, McMannis JD, Papadopoulos N, Kim K, Homsi J, Bedikian A, Hwu WJ, Hwu P, Radvanyi LG
Clin Cancer Res, 17(14):4882-4891, 01 Jun 2011
Cited by: 34 articles | PMID: 21632855 | PMCID: PMC3139726
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BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice.
Liu C, Peng W, Xu C, Lou Y, Zhang M, Wargo JA, Chen JQ, Li HS, Watowich SS, Yang Y, Tompers Frederick D, Cooper ZA, Mbofung RM, Whittington M, Flaherty KT, Woodman SE, Davies MA, Radvanyi LG, Overwijk WW, [...] Hwu P
Clin Cancer Res, 19(2):393-403, 30 Nov 2012
Cited by: 249 articles | PMID: 23204132 | PMCID: PMC4120472
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