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Search life-sciences literature (45,103,589 articles, preprints and more)

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The role of quiescent thymic progenitors in TAL/LMO2-induced T-ALL chemotolerance.
O'Connor KW, Kishimoto K, Kuzma IO, Wagner KP, Selway JS, Roderick JE, Karna KK, Gallagher KM, Hu K, Liu H, Li R, Brehm MA, Zhu LJ, Curtis DJ, Tremblay CS, Kelliher MA
Leukemia, 38(5):951-962, 29 Mar 2024
Cited by: 1 article | PMID: 38553571 | PMCID: PMC11073972
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Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death.
Roderick JE, Gallagher KM, Murphy LC, O'Connor KW, Tang K, Zhang B, Brehm MA, Greiner DL, Yu J, Zhu LJ, Green MR, Kelliher MA
Blood, 137(4):500-512, 01 Jan 2021
Cited by: 7 articles | PMID: 33507291 | PMCID: PMC7845005
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ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia.
Gallagher KM, Roderick JE, Tan SH, Tan TK, Murphy L, Yu J, Li R, O'Connor KW, Zhu J, Green MR, Sanda T, Kelliher MA
Blood Adv, 4(13):3154-3168, 01 Jul 2020
Cited by: 9 articles | PMID: 32658986 | PMCID: PMC7362368
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NOTCH Signaling in T-Cell-Mediated Anti-Tumor Immunity and T-Cell-Based Immunotherapies.
Kelliher MA, Roderick JE
Front Immunol, 9:1718, 20 Aug 2018
Cited by: 34 articles | PMID: 30967879 | PMCID: PMC6109642
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Correction: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
O'Donnell JA, Lehman J, Roderick JE, Martinez-Marin D, Zelic M, Doran C, Hermance N, Lyle S, Pasparakis M, Fitzgerald KA, Marshak-Rothstein A, Kelliher MA
J Immunol, 200(8):3020-3021, 12 Mar 2018
Cited by: 1 article | PMID: 29531167
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RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia.
Choi A, Illendula A, Pulikkan JA, Roderick JE, Tesell J, Yu J, Hermance N, Zhu LJ, Castilla LH, Bushweller JH, Kelliher MA
Blood, 130(15):1722-1733, 08 Aug 2017
Cited by: 48 articles | PMID: 28790107 | PMCID: PMC5639483
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UFD1 contributes to MYC-mediated leukemia aggressiveness through suppression of the proapoptotic unfolded protein response.
Huiting LN, Samaha Y, Zhang GL, Roderick JE, Li B, Anderson NM, Wang YW, Wang L, Laroche F, Choi JW, Liu CT, Kelliher MA, Feng H
Leukemia, 32(11):2339-2351, 25 Apr 2018
Cited by: 21 articles | PMID: 29743725 | PMCID: PMC6202254
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RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome.
Zelic M, Roderick JE, O'Donnell JA, Lehman J, Lim SE, Janardhan HP, Trivedi CM, Pasparakis M, Kelliher MA
J Clin Invest, 128(5):2064-2075, 16 Apr 2018
Cited by: 46 articles | PMID: 29664014 | PMCID: PMC5919800
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Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
O'Donnell JA, Lehman J, Roderick JE, Martinez-Marin D, Zelic M, Doran C, Hermance N, Lyle S, Pasparakis M, Fitzgerald KA, Marshak-Rothstein A, Kelliher MA
J Immunol, 200(2):737-748, 06 Dec 2017
Cited by: 20 articles | PMID: 29212904 | PMCID: PMC5760320
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BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.
Winter GE, Mayer A, Buckley DL, Erb MA, Roderick JE, Vittori S, Reyes JM, di Iulio J, Souza A, Ott CJ, Roberts JM, Zeid R, Scott TG, Paulk J, Lachance K, Olson CM, Dastjerdi S, Bauer S, Lin CY, [...] Bradner JE
Mol Cell, 67(1):5-18.e19, 29 Jun 2017
Cited by: 237 articles | PMID: 28673542 | PMCID: PMC5663500
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Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.
Carr MI, Roderick JE, Zhang H, Woda BA, Kelliher MA, Jones SN
Proc Natl Acad Sci U S A, 113(52):15024-15029, 12 Dec 2016
Cited by: 7 articles | PMID: 27956626 | PMCID: PMC5206519
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CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells.
Lian H, Li D, Zhou Y, Landesman-Bollag E, Zhang G, Anderson NM, Tang KC, Roderick JE, Kelliher MA, Seldin DC, Fu H, Feng H
Haematologica, 102(1):e17-e21, 06 Oct 2016
Cited by: 10 articles | PMID: 27758824 | PMCID: PMC5210253
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Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis.
Carr MI, Roderick JE, Gannon HS, Kelliher MA, Jones SN
Cell Rep, 16(10):2618-2629, 25 Aug 2016
Cited by: 21 articles | PMID: 27568562 | PMCID: PMC5031082
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The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.
Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, Andreeff M, Armand P, Ballen KK, Barzaghi-Rinaudo P, [...] Weinstock DM
Cancer Cell, 30(1):183, 11 Jul 2016
Cited by: 44 articles | PMID: 27479034
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The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.
Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, Andreeff M, Armand P, Ballen KK, Barzaghi-Rinaudo P, [...] Weinstock DM
Cancer Cell, 29(4):574-586, 01 Apr 2016
Cited by: 155 articles | PMID: 27070704 | PMCID: PMC5177991
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The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis.
Anderson NM, Li D, Peng HL, Laroche FJ, Mansour MR, Gjini E, Aioub M, Helman DJ, Roderick JE, Cheng T, Harrold I, Samaha Y, Meng L, Amsterdam A, Neuberg DS, Denton TT, Sanda T, Kelliher MA, Singh A, [...] Feng H
Leukemia, 30(6):1365-1374, 15 Feb 2016
Cited by: 33 articles | PMID: 26876595 | PMCID: PMC4889531
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Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199.
Chonghaile TN, Roderick JE, Glenfield C, Ryan J, Sallan SE, Silverman LB, Loh ML, Hunger SP, Wood B, DeAngelo DJ, Stone R, Harris M, Gutierrez A, Kelliher MA, Letai A
Cancer Discov, 4(9):1074-1087, 03 Jul 2014
Cited by: 157 articles | PMID: 24994123 | PMCID: PMC4154982
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Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis.
Roderick JE, Hermance N, Zelic M, Simmons MJ, Polykratis A, Pasparakis M, Kelliher MA
Proc Natl Acad Sci U S A, 111(40):14436-14441, 22 Sep 2014
Cited by: 67 articles | PMID: 25246544 | PMCID: PMC4209989
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RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.
Wolfe AL, Singh K, Zhong Y, Drewe P, Rajasekhar VK, Sanghvi VR, Mavrakis KJ, Jiang M, Roderick JE, Van der Meulen J, Schatz JH, Rodrigo CM, Zhao C, Rondou P, de Stanchina E, Teruya-Feldstein J, Kelliher MA, Speleman F, Porco JA, [...] Wendel HG
Nature, 513(7516):65-70, 27 Jul 2014
Cited by: 364 articles | PMID: 25079319 | PMCID: PMC4492470
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Leukemia propagating cells Akt up.
Gutierrez A, Roderick JE, Kelliher MA
Cancer Cell, 25(3):263-265, 01 Mar 2014
Cited by: 2 articles | PMID: 24651006
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Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia.
Reynolds C, Roderick JE, LaBelle JL, Bird G, Mathieu R, Bodaar K, Colon D, Pyati U, Stevenson KE, Qi J, Harris M, Silverman LB, Sallan SE, Bradner JE, Neuberg DS, Look AT, Walensky LD, Kelliher MA, Gutierrez A
Leukemia, 28(9):1819-1827, 20 Feb 2014
Cited by: 36 articles | PMID: 24552990 | PMCID: PMC4139485
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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Knoechel B, Roderick JE, Williamson KE, Zhu J, Lohr JG, Cotton MJ, Gillespie SM, Fernandez D, Ku M, Wang H, Piccioni F, Silver SJ, Jain M, Pearson D, Kluk MJ, Ott CJ, Shultz LD, Brehm MA, Greiner DL, [...] Bernstein BE
Nat Genet, 46(4):364-370, 02 Mar 2014
Cited by: 234 articles | PMID: 24584072 | PMCID: PMC4086945
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Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia.
Roderick JE, Gonzalez-Perez G, Kuksin CA, Dongre A, Roberts ER, Srinivasan J, Andrzejewski C, Fauq AH, Golde TE, Miele L, Minter LM
J Exp Med, 210(7):1311-1329, 03 Jun 2013
Cited by: 49 articles | PMID: 23733784 | PMCID: PMC3698520
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c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
Roderick JE, Tesell J, Shultz LD, Brehm MA, Greiner DL, Harris MH, Silverman LB, Sallan SE, Gutierrez A, Look AT, Qi J, Bradner JE, Kelliher MA
Blood, 123(7):1040-1050, 06 Jan 2014
Cited by: 105 articles | PMID: 24394663 | PMCID: PMC3924926
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1-24 of 24 results

Search life-sciences literature (45,103,589 articles, preprints and more)

Search results

The role of quiescent thymic progenitors in TAL/LMO2-induced T-ALL chemotolerance.

Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death.

ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia.

NOTCH Signaling in T-Cell-Mediated Anti-Tumor Immunity and T-Cell-Based Immunotherapies.

Correction: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.

RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia.

UFD1 contributes to MYC-mediated leukemia aggressiveness through suppression of the proapoptotic unfolded protein response.

RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome.

Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.

Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.

CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells.

Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis.

Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199.

Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis.

RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.

Leukemia propagating cells Akt up.

Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia.

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia.

c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.

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